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I Current Eomments” EUGENE GARFIELD
I Current Eomments” EUGENE GARFIELD

... water resulted in slower declines in infection prevalence and intensity that only slowly affected the disease. Jordan warns, however, that no endemic area of schistosomiasis can be considered a typical area since ecology, transmission patterns, and population vary. But principles of control can be c ...
PHYSICOCHEMICAL PROPERTIES OF HESPERIDIN NANOCRYSTAL Research Article RACHMAT MAULUDIN
PHYSICOCHEMICAL PROPERTIES OF HESPERIDIN NANOCRYSTAL Research Article RACHMAT MAULUDIN

... were located in a thermostated storage at 25 ± 0.01oC, shielded from light to prevent any degradation of the molecules. Then shaker was moved at 100 rpm and at certain time samples were withdrawn. An aliquot was filtered using Sartorius® 0.1 μm filters (Sartorius AG, Goettingen Germany) and then tra ...
Lansoprazole/C02-039 A Phase 2, Open-Label Multicenter
Lansoprazole/C02-039 A Phase 2, Open-Label Multicenter

... status or completeness of the information contained. Data should not be used in any publication or statistical analysis (including meta analysis) without prior approval from the sponsor. Patients should consult their health care professional for advice about their specific situation. ...
Vaccines and Antiviral Drugs in Pandemic
Vaccines and Antiviral Drugs in Pandemic

... predated molecular analysis of the hemagglutinin of the viruses and was based as a classification system derived from their epidemiologic characteristics. As shown in the Table, the concern that swine influenza would appear in 1976 was supported by seroarcheology, evidence in serum samples collected ...
Dow Corning Silicones in Pharmaceutical Applications
Dow Corning Silicones in Pharmaceutical Applications

... This addition reaction requires very low levels of a platinum complex as catalyst (5 20 ppm as Pt) and does not generate any by-products, hence its advantages in pharmaceutical applications (3). Using a polymer carrying many SiH groups, many vinyl endblocked chains can be crosslinked together. A lar ...
PHL 322 Antiepilepti..
PHL 322 Antiepilepti..

... Megaloplastic anemia. (corrected by folic acid) Decreased serum concentrations of folic acid, thyroxine, and vitamin K with long-term use. ...
Treatment Options for Wet Macular Degeneration (MD)
Treatment Options for Wet Macular Degeneration (MD)

... chemical groups responsible for side effects, such as the development of cataracts and elevated intraocular pressure leading to glaucoma, while preserving potency against angiogenesis. ...
NBER WORKING PAPER SERIES PHARMACEUTICAL PRICING IN EMERGING MARKETS:
NBER WORKING PAPER SERIES PHARMACEUTICAL PRICING IN EMERGING MARKETS:

... originator prices and high income countries (for example, Danzon and Chao 2000, 2004).  Danzon and Furukawa (2003, 2008) found that average drug prices vary roughly in  proportion to income across HICs, but for Brazil, Mexico and Chile drug prices are 2‐3 fold  higher relative to PCI. Empirical evid ...
The Place of Drug Product Critical Quality Parameters in Quality by
The Place of Drug Product Critical Quality Parameters in Quality by

... Along with the fast developments in the drug production and control technologies, it has been easier to comment on the drug and its production, as well as observing/seeing the defects. These developments have brought within new arrangements in the regulations. Recently added ICH Q8, Q9, Q10 and Q11 ...
Drugs of Abuse, Driving and Traffic Safety
Drugs of Abuse, Driving and Traffic Safety

... outcome measure of the driving test is the standard deviation of the lateral position (SDLP), i.e. the weaving of the car. Subjects are allowed to take over slower vehicles and are accompanied by a driving instructor with dual controls. In more than 60 on-the-road driving studies, dose-dependent imp ...
Cleaning Verification / Validation of Pharmaceutical Manufacturing
Cleaning Verification / Validation of Pharmaceutical Manufacturing

... An API supplier of Cholestyramine Resin recall the product, due to contamination with low levels of intermediates and degradants from the production of agricultural pesticides. This cross-contamination attributed to drums used to recover solvent from agricultural pesticides manufacture at another lo ...
Slide 1
Slide 1

... Copyright © 2009 Turquoise Consulting. All Rights Reserved ...
ASHP Guidelines on Pharmacy-Prepared Ophthalmic Products
ASHP Guidelines on Pharmacy-Prepared Ophthalmic Products

... 1 0. The final container should be appropriate for the ophthalmic product and its intended use and should not interfere with the stability and efficacy of the preparation.10 Many ophthalmic liquids can be packaged in sterile plastic bottles with self-contained dropper tips or in glass bottles with ...
Exposure to antidepressants and the risk of cryptogenic
Exposure to antidepressants and the risk of cryptogenic

... of CFA recorded anywhere in the GPRD record, and the date of diagnosis defined as the date of this condition. The authors have previously reviewed hospital clinic letters for a subsample of these cases and established that the diagnosis of CFA in the GPRD is reliable [15]. Six controls were individu ...
Protocol S1.
Protocol S1.

... Currently, medication and surgical ligation are valiated effective. Surgical ligation may be performed if the patient remains symptomatic after one or two courses of COX inhibitor or if COX inhibitor treatment is contraindicated. However, pharmacologic therapy remains the preferred initial treatmen ...
Aspirin® – an unparalleled “career”
Aspirin® – an unparalleled “career”

... Then, in 1971, British pharmacologist Professor John Vane discovered that the antiinflammatory properties of acetylsalicylic acid result from its ability to inhibit the body’s production of certain chemical mediators (prostaglandins) that promote inflammation and, therefore, cause pain. His research ...
Drug induced hyperpigmentation
Drug induced hyperpigmentation

...  Edema –related symptoms (lower limb swelling and heaviness) ocurred significantly more often with amlodipine ...
Short-Term Fasting Alters Cytochrome P450–Mediated Drug
Short-Term Fasting Alters Cytochrome P450–Mediated Drug

... The effects of fasting on drug metabolism in experimental models can be explained by the altered activity of nuclear transcription factors. The nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (Klein et al., 1993) serve as xenosensors, which regulate the activity of m ...
Premarin
Premarin

... Portions of this text, originally from Wikipedia, were modified and the information independently verified. Text is available under the Creative Commons  Attribution‐ShareAlike License; additional terms may apply. See Terms of Use for details. ‐ http://creativecommons.org/licenses/by‐sa/3.0/  ...
Opioid Drugs in Patients With Liver Disease: A Systematic Review
Opioid Drugs in Patients With Liver Disease: A Systematic Review

... contribution of the liver to the metabolism of carbohydrates, protein, drugs and toxins, fats and cholesterol and many other biological processes are still unknown. Liver disorders are classified into two types: acute and chronic. Different drugs are used in liver diseases to treat and control pain. ...
Front Matter
Front Matter

... incidence had greatly increased since 1870, especially among those living in barracks and prisons for more than three months. Two views prevailed as to its aetiology, namely that it was either of bacterial origin or else caused by a toxin in the rice that formed the staple diet of all those who were ...
For The Greater Good
For The Greater Good

... what should happen. The latter involves human decisions about the use of knowledge. Understanding basic concepts and principles of science and technology should precede active debate about the economcis, policies, politics, and ethics of various science - and technology-related challenges. However, ...
iCup®/ iCup® - Drug testing supplies from CLIA waived,Inc, drug tests
iCup®/ iCup® - Drug testing supplies from CLIA waived,Inc, drug tests

... Opiate refers to any drug that is derived from the opium poppy, including the natural products, morphine and codeine, and the semi-synthetic drugs such as heroin. Opioid is more general, referring to any drug that acts on the opioid receptor. Opioid analgesics comprise a large group of substances wh ...
Buprenorphine: A New Alternative in the Treatment of Opioid Addiction
Buprenorphine: A New Alternative in the Treatment of Opioid Addiction

... agonist action at opioid receptors, buprenorphine has a risk of abuse, however is lower than the other full opioid agonists. Intravenous, intranasal, even rectal administrations of pills were reported by patients who mostly prefer Subutex® which does not contain naloxone. A formulation containing bu ...
Heparin
Heparin

... sulfate can only effectively counteract heparin if 1mg of protamine sulfate is administered for every 100 IU of active heparin received. • It's important to note that Vitamin K, which is effective at promoting blood clotting, is not an effective heparin antidote, as Vitamin K cannot stop heparin fro ...
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Pharmaceutical industry



The pharmaceutical industry develops, produces, and markets drugs or pharmaceuticals for use as medications. Pharmaceutical companies may deal in generic or brand medications and medical devices. They are subject to a variety of laws and regulations that govern the patenting, testing, safety, efficacy and marketing of drugs.
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