Effects of a perindopril-based blood pressure lowering regimen on
... congestive heart failure each by about one-quarter and the risk of total coronary events, including coronary revascularisation and hospitalisation for unstable angina, by about one-fifth. These benefits were observed against a background of standard care that included antiplatelet agents and nonstud ...
... congestive heart failure each by about one-quarter and the risk of total coronary events, including coronary revascularisation and hospitalisation for unstable angina, by about one-fifth. These benefits were observed against a background of standard care that included antiplatelet agents and nonstud ...
Cardiac Catheterisation
... 3. What is going to be done? Cardiac catheterisation is an invasive test. This means we need to go inside the body to the heart. It is usually done under general anaesthetic. We need to find detailed information about your child’s heart function. This information determines how your child is treated ...
... 3. What is going to be done? Cardiac catheterisation is an invasive test. This means we need to go inside the body to the heart. It is usually done under general anaesthetic. We need to find detailed information about your child’s heart function. This information determines how your child is treated ...
View PDF - CiteSeerX
... end of ventricular depolarisation and repolarisation. The T wave is the result of ventricular repolarisation. This wave in a normal ECG is asymmetrical as the first part of this wave is more gradual than the subsequent part. The QT interval is measured from the beginning of the QRS complex to the en ...
... end of ventricular depolarisation and repolarisation. The T wave is the result of ventricular repolarisation. This wave in a normal ECG is asymmetrical as the first part of this wave is more gradual than the subsequent part. The QT interval is measured from the beginning of the QRS complex to the en ...
Assessment of Heart Rate Variabilit in Hypertrophic
... Methods and Results. To determine the clinical significance of HRV and its relation to markers of electrical and hemodynamic instability in 1CM, the 24-hour Holter recordings of 104 patients in sinus rhythm and off medication were analyzed. Five nonspectral measures of HRV were computed. The frequen ...
... Methods and Results. To determine the clinical significance of HRV and its relation to markers of electrical and hemodynamic instability in 1CM, the 24-hour Holter recordings of 104 patients in sinus rhythm and off medication were analyzed. Five nonspectral measures of HRV were computed. The frequen ...
Cardiac Pacemaker
... • The conducting bands around the circumference of the solid intraluminal probe contact the internal surface of the heart wall and electrically stimulate it. • The intramyocardial electrode is placed on the exterior surface of the heart. • A puncture wound is made in the wall of the heart, and the h ...
... • The conducting bands around the circumference of the solid intraluminal probe contact the internal surface of the heart wall and electrically stimulate it. • The intramyocardial electrode is placed on the exterior surface of the heart. • A puncture wound is made in the wall of the heart, and the h ...
Feline Cardiomyopathies
... Hypertrophic cardiomyopathy refers to an underlying problem of the heart muscle at a microscopic level which causes the muscle to become thickened. A gene mutation causing HCM has been identified in Maine Coon and Ragdoll Cats. There are likely numerous gene mutations in cats which cause this diseas ...
... Hypertrophic cardiomyopathy refers to an underlying problem of the heart muscle at a microscopic level which causes the muscle to become thickened. A gene mutation causing HCM has been identified in Maine Coon and Ragdoll Cats. There are likely numerous gene mutations in cats which cause this diseas ...
The Pacemaker Current: From Basics to the Clinics
... of working myocardium (negative inotropism) due to inhibition of Ca2+ entry. In the absence of alternative pharmacological interventions and despite the adverse side effects, β-blockers and Ca2+ antagonists are of large use in therapies requiring heart rate reduction. It is therefore not surprising ...
... of working myocardium (negative inotropism) due to inhibition of Ca2+ entry. In the absence of alternative pharmacological interventions and despite the adverse side effects, β-blockers and Ca2+ antagonists are of large use in therapies requiring heart rate reduction. It is therefore not surprising ...
draft - ACCP
... 2. Eligibility: licensed pharmacy practitioners, fellows, and residents. 3. Length: three – four weeks. Trainees can be accepted January through mid-August and October. 1 trainee at a time 4. Site/Program Description: The University of Illinois Medical Center (UIMCC) includes a 450-bed tertiary care ...
... 2. Eligibility: licensed pharmacy practitioners, fellows, and residents. 3. Length: three – four weeks. Trainees can be accepted January through mid-August and October. 1 trainee at a time 4. Site/Program Description: The University of Illinois Medical Center (UIMCC) includes a 450-bed tertiary care ...
Atrial fibrillation progression and management: A 5-year
... rule out atrial thrombi and annually in patients with comorbidities. After the first paroxysmal episode, no antiarrhythmic drug therapy was administered. Recurrent symptomatic episodes were pharmacologically managed by conventional antiarrhythmic drug therapy (propafenone, flecainide, and/or sotalol ...
... rule out atrial thrombi and annually in patients with comorbidities. After the first paroxysmal episode, no antiarrhythmic drug therapy was administered. Recurrent symptomatic episodes were pharmacologically managed by conventional antiarrhythmic drug therapy (propafenone, flecainide, and/or sotalol ...
Resolution of left ventricular postinfarction thrombi in patients
... The twice daily 2.5 mg dose of rivaroxaban resulted in significantly lower rates of all-cause and cardiovascular mortality, which was not observed with the twice daily 5.0 mg dose. The HAS-BLED score was 1–2 for the abovementioned patients, who had normal creatinine clearance and based on the above a ...
... The twice daily 2.5 mg dose of rivaroxaban resulted in significantly lower rates of all-cause and cardiovascular mortality, which was not observed with the twice daily 5.0 mg dose. The HAS-BLED score was 1–2 for the abovementioned patients, who had normal creatinine clearance and based on the above a ...
Department of Cardiothoracic Surgery
... Particularly encouraging are results for neonatal surgery – mortality of 8.2% comparing favourably to European (10.3 %), mostly because all types of malformations were treated, some with undeniable innovation, as the hybrid treatment for hypoplastic left heart syndrome, managed at first stage by the ...
... Particularly encouraging are results for neonatal surgery – mortality of 8.2% comparing favourably to European (10.3 %), mostly because all types of malformations were treated, some with undeniable innovation, as the hybrid treatment for hypoplastic left heart syndrome, managed at first stage by the ...
Studying Systemic Oxidative Stress in Heart Failure
... redox-sensitive signal transduction pathways, such as the pathway of NF kB and AP1. 1,7 Via these effects, ROS can regulate cell proliferation or apoptosis, tissue inflammation, and overall cellular function. Despite the significant progress in understanding the mechanisms of cardiovascular diseases ...
... redox-sensitive signal transduction pathways, such as the pathway of NF kB and AP1. 1,7 Via these effects, ROS can regulate cell proliferation or apoptosis, tissue inflammation, and overall cellular function. Despite the significant progress in understanding the mechanisms of cardiovascular diseases ...
- Sand Run Pharmacy
... such side effects as vomiting, anoThe primary side effects are hypotenrexia, and diarrhea. Dobermans apsion, rash at site of application, and pear to be most sensitive to these ad- tolerance that can develop with reverse effects. The second group in peated use. It’s very important that this ...
... such side effects as vomiting, anoThe primary side effects are hypotenrexia, and diarrhea. Dobermans apsion, rash at site of application, and pear to be most sensitive to these ad- tolerance that can develop with reverse effects. The second group in peated use. It’s very important that this ...
EFFECT OF EXTERNALLY APPLIED LOAD ON THE WORK DONE
... during the filling phase. This pressure may, therefore, be compared to the pre-loading skeletal muscle as suggested by Sonnenblick and Downing (5). It determines the resting I of the muscle fibres and, thereby, regul~tes the force of the ensuing contraction. S· the arterial pressure against which bl ...
... during the filling phase. This pressure may, therefore, be compared to the pre-loading skeletal muscle as suggested by Sonnenblick and Downing (5). It determines the resting I of the muscle fibres and, thereby, regul~tes the force of the ensuing contraction. S· the arterial pressure against which bl ...
Neurogenic atrial fibrillation
... post-prandial states and alcohol are also precipitating factors.8 Vagally mediated AF rarely, if ever, progresses to permanent AF. A 24-hour ECG can confirm the role of the ANS by showing progressive slowing of the heart rate over a few hours, or even a few beats, before the onset of arrhythmia.3 An ...
... post-prandial states and alcohol are also precipitating factors.8 Vagally mediated AF rarely, if ever, progresses to permanent AF. A 24-hour ECG can confirm the role of the ANS by showing progressive slowing of the heart rate over a few hours, or even a few beats, before the onset of arrhythmia.3 An ...
THE CARDIAC CYCLE
... Blood arriving at the heart cannot enter the atrium so it flows back up the jugular vein, causing the first discernible wave in the jugular venous pulse. Atrial pressure drops when the atria stop contracting. During atrial systole the atrium contracts and tops off the volume in the ventricle with on ...
... Blood arriving at the heart cannot enter the atrium so it flows back up the jugular vein, causing the first discernible wave in the jugular venous pulse. Atrial pressure drops when the atria stop contracting. During atrial systole the atrium contracts and tops off the volume in the ventricle with on ...
THE CARDIAC CYCLE
... Blood arriving at the heart cannot enter the atrium so it flows back up the jugular vein, causing the first discernible wave in the jugular venous pulse. Atrial pressure drops when the atria stop contracting. During atrial systole the atrium contracts and tops off the volume in the ventricle with on ...
... Blood arriving at the heart cannot enter the atrium so it flows back up the jugular vein, causing the first discernible wave in the jugular venous pulse. Atrial pressure drops when the atria stop contracting. During atrial systole the atrium contracts and tops off the volume in the ventricle with on ...
Understanding Heart Rhythm Disorders
... • Ventricular arrhythmia, which starts from the ventricle (the lower chamber where blood is pushed out of the heart) and takes over for the natural pacemaker. Some arrhythmias are benign and don’t cause problems or symptoms. Others may lead to life-threatening conditions such as stroke and heart fa ...
... • Ventricular arrhythmia, which starts from the ventricle (the lower chamber where blood is pushed out of the heart) and takes over for the natural pacemaker. Some arrhythmias are benign and don’t cause problems or symptoms. Others may lead to life-threatening conditions such as stroke and heart fa ...
Indications and Recommendations for Pacemaker Therapy
... types of neurocardiogenic syncopal syndromes. Classically, it is preceded by a prodrome of nausea and diaphoresis and is associated with severe bradycardia. Episodes usually are triggered by pain, anxiety, or stress. A family history of syncope may be present. Pacing therapy for patients with refrac ...
... types of neurocardiogenic syncopal syndromes. Classically, it is preceded by a prodrome of nausea and diaphoresis and is associated with severe bradycardia. Episodes usually are triggered by pain, anxiety, or stress. A family history of syncope may be present. Pacing therapy for patients with refrac ...
Left ventricular systolic and diastolic dyssynchrony
... ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; CCS, Canadian Cardiovascular Society; DVD, double-vessel disease; LMD, left main stem disease; NS, not significant; SVD, single-vessel disease; TVD, triple-vessel disease. CAD patients with Preserved EF (n = 94) ...
... ACEI, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; CCS, Canadian Cardiovascular Society; DVD, double-vessel disease; LMD, left main stem disease; NS, not significant; SVD, single-vessel disease; TVD, triple-vessel disease. CAD patients with Preserved EF (n = 94) ...
Anterior MI
... (but not in the SA node), therefore the contour of the P wave, the PR interval, and the timing are different than a normally generated pulse from the SA node. ...
... (but not in the SA node), therefore the contour of the P wave, the PR interval, and the timing are different than a normally generated pulse from the SA node. ...
ATRIAL SYSTOLE
... Blood arriving at the heart cannot enter the atrium so it flows back up the jugular vein, causing the first discernible wave in the jugular venous pulse. Atrial pressure drops when the atria stop contracting. During atrial systole the atrium contracts and tops off the volume in the ventricle with on ...
... Blood arriving at the heart cannot enter the atrium so it flows back up the jugular vein, causing the first discernible wave in the jugular venous pulse. Atrial pressure drops when the atria stop contracting. During atrial systole the atrium contracts and tops off the volume in the ventricle with on ...
The haplotype of the growth-differentiation factor 15 gene is
... GDF15 (growth-differentiation factor 15) is a novel antihypertrophic factor which is induced in the heart in response to pressure overload and plays an important regulatory role in the process of hypertrophy. In the present study, we have investigated the relationship between GDF15 gene variants and ...
... GDF15 (growth-differentiation factor 15) is a novel antihypertrophic factor which is induced in the heart in response to pressure overload and plays an important regulatory role in the process of hypertrophy. In the present study, we have investigated the relationship between GDF15 gene variants and ...
Assessment of T-Wave Alternans Used to Predict Lethal Arrhythmia
... Comparison of the Predictivity of TWA With the Spectral and MMA Methods - Spectral Method: one-half of the average TWA magnitude across the entire JT interval for 128 beats - MMA method: the peak TWA level at any point within the JT interval for each 10 to 15-s interval • Hazard ratios for predicti ...
... Comparison of the Predictivity of TWA With the Spectral and MMA Methods - Spectral Method: one-half of the average TWA magnitude across the entire JT interval for 128 beats - MMA method: the peak TWA level at any point within the JT interval for each 10 to 15-s interval • Hazard ratios for predicti ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.