Mechanisms of Heart Failure
... Pathophysiological mechanisms that causes raised filling pressures and/ poor tissue perfusion: HF • Afterload: – Systemic and pulmonary resistance – Physical characteristics of the vessel walls – The volume of blood that is ejected. Increase in after load decreases CO with an increase in end-diasto ...
... Pathophysiological mechanisms that causes raised filling pressures and/ poor tissue perfusion: HF • Afterload: – Systemic and pulmonary resistance – Physical characteristics of the vessel walls – The volume of blood that is ejected. Increase in after load decreases CO with an increase in end-diasto ...
- Wiley Online Library
... genes, the alpha-dystrobrevin gene, the lamin A/C gene, and the tafazzin gene have been identified in association with LVNC.17 Thus, it is increasingly recognized that certain gene mutations encoding for sarcomeric proteins can lead to a range of disease phenotypes including LVNC as well as hypertrop ...
... genes, the alpha-dystrobrevin gene, the lamin A/C gene, and the tafazzin gene have been identified in association with LVNC.17 Thus, it is increasingly recognized that certain gene mutations encoding for sarcomeric proteins can lead to a range of disease phenotypes including LVNC as well as hypertrop ...
Don`t Always Blame CREST Syndrome for Heart Problems
... ventricular tachycardia (VT).7 In early disease, the presence of VT is secondary to ARVC and may be a harbinger for sudden cardiac death or heart failure. In late disease, ARVC may lead to heart failure, which itself can produce VT. The ventricular arrhythmias predominantly originate in the RV,but a ...
... ventricular tachycardia (VT).7 In early disease, the presence of VT is secondary to ARVC and may be a harbinger for sudden cardiac death or heart failure. In late disease, ARVC may lead to heart failure, which itself can produce VT. The ventricular arrhythmias predominantly originate in the RV,but a ...
Clinical Decision Making - Test 2
... ○ Chest Exam Lung Exam Signs and Symptoms ○ Dyspnea – shortness of breath (grade IV is the worst) ○ Orthopnea – shortness of breath when lying down ○ Paroxysmal Nocturnal Dyspnea – typically associated with pulmonary edema ○ Cough – classify as productive vs. non-productive Productive – sugges ...
... ○ Chest Exam Lung Exam Signs and Symptoms ○ Dyspnea – shortness of breath (grade IV is the worst) ○ Orthopnea – shortness of breath when lying down ○ Paroxysmal Nocturnal Dyspnea – typically associated with pulmonary edema ○ Cough – classify as productive vs. non-productive Productive – sugges ...
summary / samenVattInG Louis BW.indd 125 06-05-10 11:21
... Lessons from the left heart The right ventricle as a potential treatment target Pulmonary arterial hypertension (PH) is a rare disease, which is characterized by excessive remodeling of the pulmonary vasculature, resulting in increased pulmonary vascular resistance and right ventricular (RV) afterlo ...
... Lessons from the left heart The right ventricle as a potential treatment target Pulmonary arterial hypertension (PH) is a rare disease, which is characterized by excessive remodeling of the pulmonary vasculature, resulting in increased pulmonary vascular resistance and right ventricular (RV) afterlo ...
Suspected Post-Chemotherapy Cardiomyopathy Hiding Severe
... Anthracycline medications are effective for the treatment of many malignancies but their use is limited by their possible cardiotoxicity as well as other hematological, gastroenteric and cutaneous disorders, so that guidelines for the monitoring of adverse effects should be strictly followed (1). Ca ...
... Anthracycline medications are effective for the treatment of many malignancies but their use is limited by their possible cardiotoxicity as well as other hematological, gastroenteric and cutaneous disorders, so that guidelines for the monitoring of adverse effects should be strictly followed (1). Ca ...
Cardiac muscle tissue
... Coronary artery disease (CAD) is a condition in which plaque builds up inside the coronary arteries that supply heart muscle with oxygenrich blood. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. When plaque builds up in the arteries, the condition is called ...
... Coronary artery disease (CAD) is a condition in which plaque builds up inside the coronary arteries that supply heart muscle with oxygenrich blood. Plaque is made up of fat, cholesterol, calcium, and other substances found in the blood. When plaque builds up in the arteries, the condition is called ...
The Fetal Heart – above and beyond the Four Chamber View!
... Aorta sweeps to fetal right – ballerina’s foot Pulmonary artery crosses over aorta and runs from sternum to spine, continuing as arterial duct ...
... Aorta sweeps to fetal right – ballerina’s foot Pulmonary artery crosses over aorta and runs from sternum to spine, continuing as arterial duct ...
Short QT syndrome
... symptoms (syncope and palpitations) and family history of syncope, sudden death or atrial fibrillation at a young age. Secondary causes of short QT must also be excluded and include hyperthermia, hyperkalemia, hypercalcemia, acidosis and alterations of the autonomic tone. When evaluating the ECG (fi ...
... symptoms (syncope and palpitations) and family history of syncope, sudden death or atrial fibrillation at a young age. Secondary causes of short QT must also be excluded and include hyperthermia, hyperkalemia, hypercalcemia, acidosis and alterations of the autonomic tone. When evaluating the ECG (fi ...
Sudden Cardiac Death in Young Athletes
... Interscholastic Head Injury Safety Training Program by the 2011-2012 school year. • All school districts, charter, and non-public schools that participate in interscholastic sports will distribute annually this educational fact to all student athletes and obtain a signed acknowledgement from each pa ...
... Interscholastic Head Injury Safety Training Program by the 2011-2012 school year. • All school districts, charter, and non-public schools that participate in interscholastic sports will distribute annually this educational fact to all student athletes and obtain a signed acknowledgement from each pa ...
Sympathetic denervation in the treatment of fatal arrhythmias in long
... a treatment method recommended following the ICD implantation, as it is more effective compared to the catheter ablation.[2] In conclusion, long QT syndrome may present with a varying clinical features. Although such patients may be asymptomatic, they may also present with uncontrolled ventricular a ...
... a treatment method recommended following the ICD implantation, as it is more effective compared to the catheter ablation.[2] In conclusion, long QT syndrome may present with a varying clinical features. Although such patients may be asymptomatic, they may also present with uncontrolled ventricular a ...
Cardiomyopathies - Society of Cardiovascular Anesthesiologists
... develop with greater involvement of the MV and TV subvalvular apparatus producing valve insufficiency and/or stenosis. Involvement of the ventricular apex results in obliteration of the cavity, which may be further complicated by thrombus formation. Echocardiography demonstrates bi-atrial enlargemen ...
... develop with greater involvement of the MV and TV subvalvular apparatus producing valve insufficiency and/or stenosis. Involvement of the ventricular apex results in obliteration of the cavity, which may be further complicated by thrombus formation. Echocardiography demonstrates bi-atrial enlargemen ...
managing disease together
... Quadripolar Pacing Indications: St. Jude Medical™ ICDs and CRT-Ds are intended to provide ventricular antitachycardia pacing and ventricular defibrillation for automated treatment of life-threatening ventricular arrhythmias. AF Suppression™ pacing is indicated for suppression of paroxysmal or persis ...
... Quadripolar Pacing Indications: St. Jude Medical™ ICDs and CRT-Ds are intended to provide ventricular antitachycardia pacing and ventricular defibrillation for automated treatment of life-threatening ventricular arrhythmias. AF Suppression™ pacing is indicated for suppression of paroxysmal or persis ...
Acute Myocardial Infarction/Complications
... LVEF should be measured in all patients (LOE: C). Patients with an initially reduced LVEF who are possible candidates for ICD therapy should undergo re-evaluation of LVEF ≥40days after discharge (LOE: B). Suspected complications of MI (LOE: C). Noninvasive testing for ischemia should be performed be ...
... LVEF should be measured in all patients (LOE: C). Patients with an initially reduced LVEF who are possible candidates for ICD therapy should undergo re-evaluation of LVEF ≥40days after discharge (LOE: B). Suspected complications of MI (LOE: C). Noninvasive testing for ischemia should be performed be ...
Pediatric Dysrhythmias Board Review
... Third degree AV block May be asymptomatic – follow clinically Slower the heart rate, and wide QRS escape rhythms place into high risk group May need implantable pacemaker: significant bradycardias, syncope, exercise intolerance, ventricular dysrhythmias, or ventricular arrhythmias, structural d ...
... Third degree AV block May be asymptomatic – follow clinically Slower the heart rate, and wide QRS escape rhythms place into high risk group May need implantable pacemaker: significant bradycardias, syncope, exercise intolerance, ventricular dysrhythmias, or ventricular arrhythmias, structural d ...
Right ventricular function in critically ill patients
... for maintaining hemodynamic stability in critically ill patients who suffer from sudden increases of right ventricular pressure overload and/or severely decreased right ventricular contractility. The morphological and functional assessment of the right ventricle is usually performed by bedside echoc ...
... for maintaining hemodynamic stability in critically ill patients who suffer from sudden increases of right ventricular pressure overload and/or severely decreased right ventricular contractility. The morphological and functional assessment of the right ventricle is usually performed by bedside echoc ...
Lecture Notes
... 1. Preload stretch - Frank - Starling law - the greater the stretch on cardiac fibers just before they contract (draws myosin fibers closer together) increases their force of contraction, the more blood is ejected from the ventricle the heart is filled during diastole the greater the force of contra ...
... 1. Preload stretch - Frank - Starling law - the greater the stretch on cardiac fibers just before they contract (draws myosin fibers closer together) increases their force of contraction, the more blood is ejected from the ventricle the heart is filled during diastole the greater the force of contra ...
Hypertension Systolic ≥140 or Diastolic ≥ 90 Stage I systolic=140
... Palpitations, fatigue or poor exercise tolerance, mild dyspnea, presyncope. Less common symptoms o Angina, profound dyspnea, or syncope. o Tachycardia may or may not be present, depending on the degree of AV block associated with the atrial flutter activity The heart rate is often approximatel ...
... Palpitations, fatigue or poor exercise tolerance, mild dyspnea, presyncope. Less common symptoms o Angina, profound dyspnea, or syncope. o Tachycardia may or may not be present, depending on the degree of AV block associated with the atrial flutter activity The heart rate is often approximatel ...
Cong HD Patho Samia 1 of 2
... factors affecting anaesthetic risk in congenital heart disease Pulmonary ...
... factors affecting anaesthetic risk in congenital heart disease Pulmonary ...
Progression from hypertrophic to dilated cardiomyopathy in mice
... generating muscle force. These mutations are predominantly missense mutations or short deletions that do not disrupt the genetic reading frame, but they instead appear to produce full-length mutated myosin molecules that become incorporated into the sarcomere (40). The advent of mouse models for HCM ...
... generating muscle force. These mutations are predominantly missense mutations or short deletions that do not disrupt the genetic reading frame, but they instead appear to produce full-length mutated myosin molecules that become incorporated into the sarcomere (40). The advent of mouse models for HCM ...
Name of presentation
... • Prognosis depends on severity – Mild – 0-50 mm Hg – Moderate – 50-100 mm Hg – Severe - >100 mm Hg ...
... • Prognosis depends on severity – Mild – 0-50 mm Hg – Moderate – 50-100 mm Hg – Severe - >100 mm Hg ...
Dunwoody AED
... external defibrillators). After determining that Fleetwood’s heart was in a fatal rhythm known as ventricular fibrillation--or VF-- the device prompted the officer to push the shock button. The man’s wife and 31-year-old daughter watched as the deputy delivered the shock and started CPR. ...
... external defibrillators). After determining that Fleetwood’s heart was in a fatal rhythm known as ventricular fibrillation--or VF-- the device prompted the officer to push the shock button. The man’s wife and 31-year-old daughter watched as the deputy delivered the shock and started CPR. ...
Title: The determinants of right ventricular failure in patients admitted
... RV failure has been shown to be a strong predictor of poor outcome. It has been shown that pulmonary hypertension, which may lead to RV failure, is not related to the degree of LV systolic dysfunction, but is strongly associated with diastolic dysfunction, suggesting that the severity or the degree ...
... RV failure has been shown to be a strong predictor of poor outcome. It has been shown that pulmonary hypertension, which may lead to RV failure, is not related to the degree of LV systolic dysfunction, but is strongly associated with diastolic dysfunction, suggesting that the severity or the degree ...
Medical Coverage Policy Wearable and Portable Cardioverter
... treatment, and left ventricular ejection fraction of 35% or less; or o Ischemic cardiomyopathy with NYHA functional Class I symptoms, a history of myocardial infarction at least 40 days before ICD treatment, and left ventricular ejection fraction of 30% or less; or o Nonischemic dilated cardiomy ...
... treatment, and left ventricular ejection fraction of 35% or less; or o Ischemic cardiomyopathy with NYHA functional Class I symptoms, a history of myocardial infarction at least 40 days before ICD treatment, and left ventricular ejection fraction of 30% or less; or o Nonischemic dilated cardiomy ...
Fall 2011 - Steven M. Gootter Foundation
... In an unparalleled move to prevent avoidable deaths from sudden cardiac arrest, the Steven M. Gootter Foundation has provided automated external defibrillators (AEDs) to more than 40 local schools, places of worship, and recreational centers. Organizations the Foundation has donated AEDs to include ...
... In an unparalleled move to prevent avoidable deaths from sudden cardiac arrest, the Steven M. Gootter Foundation has provided automated external defibrillators (AEDs) to more than 40 local schools, places of worship, and recreational centers. Organizations the Foundation has donated AEDs to include ...
Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.