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An Introduction to the Cardiovascular System
An Introduction to the Cardiovascular System

... 20-1 Anatomy of the Heart • Heart Disease - Coronary Artery Disease • Myocardial infarction (MI), or heart attack • Consequences depend on the site and nature of the circulatory blockage • If it occurs near the start of one of the coronary arteries: • The damage will be widespread and the heart may ...
Chapter 20 The Heart An Introduction to the Cardiovascular System
Chapter 20 The Heart An Introduction to the Cardiovascular System

... 20-1 Anatomy of the Heart • Heart Disease - Coronary Artery Disease • Myocardial infarction (MI), or heart attack • Consequences depend on the site and nature of the circulatory blockage • If it occurs near the start of one of the coronary arteries: • The damage will be widespread and the heart may ...
Patent Ductus Arteriosus - Association of Surgical Technologists
Patent Ductus Arteriosus - Association of Surgical Technologists

... thus permitting the placement of a suture (3-0 silk) through the edges of the pleura. rhe assistant applies a hemostat to the ends of the suture and retracts the pleura. The surgeon carefully dissects between the aorta and pulmonary artery with Metzenbaurn scissors to expose the ductus. A heavy silk ...
Löffler`s Endocarditis: First Report of Successful Mitral and
Löffler`s Endocarditis: First Report of Successful Mitral and

... eosinophilopoetic cytokines. Complex HES is used to describe patients who cannot be classified under primary or secondary HES but who present with clinical stigmata of HES. Eosinophils tend to be polyclonal in these cases. Some experts have called for the elimination of the classification of idiopat ...
Resolution of Left Bundle Branch Block–Induced Cardiomyopathy
Resolution of Left Bundle Branch Block–Induced Cardiomyopathy

... These observations support the existence of a specific LBBB-induced cardiomyopathy resolved by CRT. Its prevalence, time course, and risk factors need to be prospectively studied. (J Am Coll Cardiol 2013;xx:xxx) © 2013 by the American College of Cardiology Foundation ...
electrocardiographic diagnosis of left ventricular hypertrophy
electrocardiographic diagnosis of left ventricular hypertrophy

... however, sensitivity can be increased by combining Sokolow Lyons voltage criteria and Cornell voltage criteria with Romhilt-Estes point score. ECG is however still recommended as a routine investigation because of its cost effectiveness and easy availability. Key words: Left ventricular hypertrophy, ...
Cardiac structure and function in humans: a new cardiovascular
Cardiac structure and function in humans: a new cardiovascular

... Medical Instruments, $2,500) to measure arterial pressure and electronically calculate mean arterial pressure (while the pressure cuff also measured heart rate, this was mostly collected from the echo). The total expense was a one-time cost of $15,000. Experimental setup and the need for a good echo ...
Pseudoaneurysm in the Left Ventricular Outflow Tract
Pseudoaneurysm in the Left Ventricular Outflow Tract

... of MDCT to detect and evaluate left ventricular outflow tract (LVOT) pseudoaneurysms in patients who have undergone aortic valve replacement with prosthetic valves. We used MDCT to scan 21 such patients, 3 of whom had a small pseudoaneurysm in the LVOT. Each pseudoaneurysm projected away from the LV ...
Myxomatous degeneration ofmitral valve
Myxomatous degeneration ofmitral valve

... application of this technique will depend upon improving its resolution and studying its sensitivity and specificity in a large population of patients with suspected mitral valve prolapse. Although the absolute diagnostic criteria for mitral valve prolapse have not been established, the left ventric ...
Sympathovagal Balance Prior to Onset of
Sympathovagal Balance Prior to Onset of

... 40 bpm; median VT run length: 4 cycles) with RMIVT. A total of 36 clusters of nonsustained episodes of RMIVT preceded by ≥1 hour of sinus rhythm without VT were analyzed (25 minutes before the onset of RMIVT divided into five 5-minute periods; 8 minutes before onset of RIMVT divided into eight 1-min ...
Diastolic Heart Failure Is A Cardiac Problem-Debate - sha
Diastolic Heart Failure Is A Cardiac Problem-Debate - sha

... preserved left ventricular ejection fraction (LVEF), variably  defined as an LVEF ≥ 40%, ≥45%, or ≥ 50%. • When these patients have invasive or non‐invasive evidence of  abnormal diastolic function (either abnormal relaxation, filling or  stiffness) they are said to have ‘‘diastolic HF’ Gaasch WH. D ...
First-in-Man Implantation of Left Ventricular
First-in-Man Implantation of Left Ventricular

... approach to the remodeling itself is a mechanical intervention to decrease the LV volume or constrain the ventricle from further enlargement. Several surgical approaches have been advocated in patients with a dilated LV, including partial left ventriculectomy (Batista procedure), cardiomyoplasty, an ...
Echocardiographic Effects of Eplerenone and Aldosterone in
Echocardiographic Effects of Eplerenone and Aldosterone in

... Figure 3. interval plot Cardiac index comparison between SHR and WKY strains over time. criteria for Grade I diastolic dysfunction (12). The calculation of index of myocardial performance (Tei Index) used aortic ejection time (ET) and mitral valve closure to opening time (MCO) (12). MCO is the sum o ...
File - Wk 1-2
File - Wk 1-2

... ahead of ventricles, acting as primer pumps, with the ventricles then providing the major source of power for moving the blood through the vascular system - diastole – relaxation where heart fills with blood - systole – contraction ...
Dispersion of QT interval in premature ventricular beats
Dispersion of QT interval in premature ventricular beats

... cardiac death. T h e presence of late potentials on t h e signalaveraged ECG [13,14] as well as reduced heart rate variability [15,16] and increased QT interval dispersion in sinus beats [2,17] have been shown to predict spontaneous sustained ventricular tachycardia and suddcn cardiac death. However ...
Cardiovascular Ultrasound
Cardiovascular Ultrasound

... with angiotensin-converting enzyme (ACE) inhibitors diminish LV dyssynchrony during the progression of pacing-induced HF, and beta-blocker therapy stimulates increases in local contractility and decreases in intraventricular dyssynchrony [6,19]. However, the relationship between RSD and LV dyssynchr ...
2010 Pediatric Cardiac and PVD Imaging Guidelines
2010 Pediatric Cardiac and PVD Imaging Guidelines

...  Systematic screening is usually not indicated for first-degree relatives who are younger than age 12 unless there is a high-risk family history or the child is involved in particularly intense competitive sports.  Affected individuals identified through family screening or otherwise should be eva ...
Diastolic Dysfunction and Its Management in Elderly Patients
Diastolic Dysfunction and Its Management in Elderly Patients

... surrounds cardiomyocytes.7 In addition, local myocardial neuroendocrine activation can impair relaxation and increase stiffness. Activation of neurohormones (eg, the renin-angiotensin-aldosterone system) can act directly to alter diastolic properties or can act indirectly by disturbing calcium hemos ...
Sudden Cardiac Death in Thrombotic Thrombocytopenic Purpura
Sudden Cardiac Death in Thrombotic Thrombocytopenic Purpura

... de pointes was hypocalcemia induced by plasma exchange. Therefore, we think that hypocalcemia, namely, complication of plasma exchange may contribute to sudden cardiac death. In conclusion, TTP is an uncommon disorder that carries a high fatality rate. Its cardiac involvement is always present by se ...
Cardiovascular Features of Heart Failure With Preserved Ejection
Cardiovascular Features of Heart Failure With Preserved Ejection

... Manuscript received January 18, 2006; revised manuscript received August 8, 2006, accepted August 14, 2006. ...
insight review articles
insight review articles

... its restriction to the heart. Although the affected K+ channel genes are expressed in various tissues, the phenotype hints that the physiological roles of these genes are most crucial in the heart. In contrast, a rare genetic disease known as Andersen’s syndrome, in which long-QT syndrome is associa ...
Summer 2015, Volume XXV, No. 2
Summer 2015, Volume XXV, No. 2

... patients. Five-year results of the PARTNER 1B trial, which compared TAVR with medical treatment in this population, were presented at this year’s annual scientific session of the American College of Cardiology (ACC) and simultaneously published in The Lancet (2015 Mar 15). In this study, TAVR result ...
Atrioventricular Communication in the Wolff-Parkin son
Atrioventricular Communication in the Wolff-Parkin son

... ROSENBERG ET AL. ...
The Heart: Part One
The Heart: Part One

... and intraventricular pressure falls, blood flows back from arteries, filling the cusps of semilunar valves and forcing them to close. (b) Semilunar valves closed ...
Point of View The Long QT Interval Syndrome
Point of View The Long QT Interval Syndrome

... suppress arrhythmias. Not all QT interval prolongation is arrhythmogenic, nor is all QT interval shortening antiarrhythmic. Uniform changes in refractoriness throughout the ventricle are probably more important. Whether such dispersion in recovery of excitability causes arrhythmias in patients with ...
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Hypertrophic cardiomyopathy



Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.
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