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... correlation between the functional imaging data and the clinical picture. When the patient is craving for alcohol, her brain is characterized by beta activity in the ACC and PCC in comparison to non-addicted brains, and these areas are phase synchronized (lagged), meaning co-activated. Normally thes ...
Endpoints in Clinical Trials
Endpoints in Clinical Trials

... Measures taken to minimizing bias Treatment groups (drug & control), ...
Pharmacoresistant Epilepsy: How..!? How to define? How to
Pharmacoresistant Epilepsy: How..!? How to define? How to

... family has recently been described, RLIP76 (RALBP1), which may have a predominant role in resistance to AEDs. It has been shown that it is expressed exclusively in brain endothelial cells, and is especially prominent in epileptic tissue of patients operated on for RE. ...
At the root of embodied cognition: Cognitive science meets
At the root of embodied cognition: Cognitive science meets

... whatever he looks at’’ (Gibson, 1979, p. 223). The concept of affordance implies interaction between characteristics in the environment and an organismÕs sensorimotor capacity. The mere observation of an object, even in absence of any explicit behavior directed at it, allows an organism to directly p ...
33 Pleura
33 Pleura

... posterior diameter of the thorax. Contraction of intercostal muscles results in the rotation of the second to the seventh rib arches at the costosternal and costovertebral joints. This movement referred to as the bucket-handle movement describes the elevation of the ribs and the eversion of their l ...
NIH Public Access
NIH Public Access

... nutrient in vivo. In SHR stroke study #1, experimental stroke outcome data revealed that the Tocomin-fed rats tended (p = 0.057, Fig. 5E) to have reduced injury following stroke than the control group. The study was repeated with a modified experimental design including a more pure form of the suppl ...
An Optogenetic Approach to Understanding the Neural Circuits of Fear
An Optogenetic Approach to Understanding the Neural Circuits of Fear

... here). This approach has not been demonstrated for PV interneurons, however, and can be nonoptimal for targeting specific cell populations. This is because most viruses have limited packaging capacity, making it necessary to use truncated versions of tissue specific promoters, which can reduce cell- ...
Auditory Brain Development in Children With Hearing Loss– Part One
Auditory Brain Development in Children With Hearing Loss– Part One

... riving higher-order meaning from the sound we hear is cerareas of the brain. Specifically, activity in response to auditory tainly a complex process. “Fundamentally, everything that stimulation was observed both in primary and secondary audicomes into our minds reduces to patterns of neural activity ...
High-performance genetically targetable optical neural
High-performance genetically targetable optical neural

... indicated; n 5 16 neurons), and after light cessation, Arch currents fell with an 85–15% offset time of 19.3 6 2.9 ms. Under continuous yellow illumination, Arch photocurrent declined (Fig. 1d, e), as did the photocurrents of all of the opsins in our screen. However, unlike all of the halorhodopsins ...
Impaired associative learning in schizophrenia: behavioral and
Impaired associative learning in schizophrenia: behavioral and

... In the human brain, the interplay between evolutionarily mature prefrontal and hippocampal regions underlies associative learning. Whereas the precise contributions of each of these regions is the subject of debate (McClelland et al. 1995), conscious associative encoding may involve persistent prefr ...
notes as
notes as

... Is preprocessing cheating? • It seems like cheating if the aim to show how powerful learning is. The really hard bit is done by the preprocessing. • Its not cheating if we learn the non-linear preprocessing. – This makes learning much more difficult and much more interesting.. • Its not cheating if ...
Carlson (7e) PowerPoint Lecture Outline Chapter 3: Structure of the
Carlson (7e) PowerPoint Lecture Outline Chapter 3: Structure of the

... This multimedia product and its contents are protected under copyright law. The following are prohibited by law: •any public performance or display, including transmission of any image over a network; •preparation of any derivative work, including extraction, in whole or in part, of any images; •any ...
Douglas B. Webster and Molly Webster
Douglas B. Webster and Molly Webster

... than auditory supports the concept that neuronal change is likely.” ...
Dissecting appetite
Dissecting appetite

... A picture of the anatomical configuration of this complex web of neurons is of little value, however, if the function of a particular neuron, and where it fits in the wiring diagram, is unknown. In the 1980s, there were few ways of doing mechanistic studies in the brain other than making cuts. But i ...
The fish: What potential for awareness?
The fish: What potential for awareness?

... It is the contention of this school of thought that there are no areas of the fish brain of sufficient complexity, to replace the neocortex, that are not already committed to other functions (Rose 2002). In addition, the neocortical argument contends that avoidance learning, or fear conditioning ...
Altered States of Consciousness
Altered States of Consciousness

... – “sweeping or scanning” total a rate of 40 times per second – Each sweep results in a single image or “moment of consciousness” – Intralaminar nucleus, a kind of doughnut of cells within the thalamus, has nerve cells that send out long axons that reach to every part of the cerebral cortex. Signific ...
Insights into schizophrenia using positron emission tomography
Insights into schizophrenia using positron emission tomography

... poor performance on working memory tasks related to the prefrontal cortex.9 An explanation of these cognitive distortions might be the inability to modify behaviour effectively with the demands of a task, resulting in inflexibility and impulsivity in performance in schizophrenia. It has been difficu ...
perceptionlecture5
perceptionlecture5

... Is a set of Reichardt detectors is sensitive to motion in one direction and only in a particular speed? It seems like an inefficient design since a great number of neurons will be required to encode motion in all possible directions and speed, unless each of them can actually encode for a small ran ...
Running head: AGING BRAIN
Running head: AGING BRAIN

... When brains of people over the age of 60 were compared with those of adults under 35, clear differences emerged (Reuter-Lorenz, 2000) that were not contradictory to what behavioral studies have suggested. For instance, one of the areas of the brain that suffers the most atrophy is the hippocampus (R ...
Methods of Studying The Nervous System - U
Methods of Studying The Nervous System - U

... – in an electrooculogram (EOG) eye movements are recorded by placing four electrodes around the eye; the signals result from the fact that the front of the eye is more positively charged than the back – The direction of movement can be inferred from the relation between the activity recorded on two ...
Specialized Neurotransmitters Dopamine
Specialized Neurotransmitters Dopamine

... gap and attach themselves to SPECIAL RECEPTORS on the membrane of the neuron receiving the impulse. This now causes the electrical impulse to be regenerated. After the neurotransmitter relays it message it is rapidly REMOVED or DESTROYED, thus halting its effect. ENZYMES, taken up again by the axon ...
learning objectives for nervous tissue and nervous system
learning objectives for nervous tissue and nervous system

... 7. Give the names of the lobes of the cerebrum. Identify the names for the divisions which separate the lobes. 8. What are four generalizations that can be made about cerebral cortex functions? 9. Where are the cortical areas controlling motor functions? Describe basic function of primary (somatic) ...
FREE Sample Here
FREE Sample Here

...  The myelin sheath, the fatty white coating of the axon, prevents impulses from being misdirected. 2.3 Neurotransmitters: The Neuron's Messengers: What are neurotransmitters, and what do they contribute to nervous system functioning?  Neurotransmitters are chemicals released into the synaptic clef ...
Viewpoint - Columbia University
Viewpoint - Columbia University

... Furthermore, we continually receive noisy sensory cues about objects in the world. We must reliably integrate such noisy evidence over time in order to make perceptual decisions. Both attentional shifting and decision making require robust temporal control and hence place stringent constraints on th ...
Specialized Neurons, Their Characteristics And
Specialized Neurons, Their Characteristics And

... This article introduces a fresh theory of consciousness based on complex neural circuitry, as envisioned from the novel perspective of electrical circuit science. Circuit science goes well beyond molecular science to show a need for certain specialized neurons during everyday brain operations. For e ...
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Metastability in the brain

In the field of computational neuroscience, the theory of metastability refers to the human brain’s ability to integrate several functional parts and to produce neural oscillations in a cooperative and coordinated manner, providing the basis for conscious activity.Metastability, a state in which signals (such as oscillatory waves) fall outside their natural equilibrium state but persist for an extended period of time, is a principle that describes the brain’s ability to make sense out of seemingly random environmental cues. In the past 25 years, interest in metastability and the underlying framework of nonlinear dynamics has been fueled by advancements in the methods by which computers model brain activity.
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