Senior Scientist Computational Biology - Pharma
... approach integrates both small molecule and cell-based therapies and spans the key functions required to generate a broad, deep and diverse pipeline of new drugs and cell therapy candidates, including: cell biology, genomics, proteomics and informatics technologies for identifying and validating cli ...
... approach integrates both small molecule and cell-based therapies and spans the key functions required to generate a broad, deep and diverse pipeline of new drugs and cell therapy candidates, including: cell biology, genomics, proteomics and informatics technologies for identifying and validating cli ...
Fatal intoxication due to tramadol alone Case report and review of
... whom death could be attributed to tramadol poisoning alone is limited to 8, including this case, as summarized in Table 1 [3,8,13–15]. In only one other case than ours, the clinical course before death was known [15]. As blood concentrations in tramadol-associated deaths overlap with subjects arrest ...
... whom death could be attributed to tramadol poisoning alone is limited to 8, including this case, as summarized in Table 1 [3,8,13–15]. In only one other case than ours, the clinical course before death was known [15]. As blood concentrations in tramadol-associated deaths overlap with subjects arrest ...
Peer-reviewed Article PDF
... process of cycloserine in lung is similar to that in blood. To kill Mycobacterium tuberculosis often requires combined action of multiple medications. So the treatment effect is very difficult to be judged by single effect of medicines. Treatment of multidrug resistant TB needs of long-term use of d ...
... process of cycloserine in lung is similar to that in blood. To kill Mycobacterium tuberculosis often requires combined action of multiple medications. So the treatment effect is very difficult to be judged by single effect of medicines. Treatment of multidrug resistant TB needs of long-term use of d ...
QA135_4chondroitin_DI
... origin but may be from other sources (5). The quality of chondroitin sulphate in several nutraceuticals has been found to be poor therefore it has been recommended that pharmaceutical-grade chondroitin is used (2). ...
... origin but may be from other sources (5). The quality of chondroitin sulphate in several nutraceuticals has been found to be poor therefore it has been recommended that pharmaceutical-grade chondroitin is used (2). ...
Inconspicuous and Miscalculated Opioid Risks
... *These agents lack the 6-OH group of morphine, possibly decreasing cross-sensitivity within the phenanthrene group. Reisine T, Pasternak G. Opioid analgesics and antagonists. In: Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Gilman AG, eds. Goodman and Gilman’s The Pharmacological Basis of Therape ...
... *These agents lack the 6-OH group of morphine, possibly decreasing cross-sensitivity within the phenanthrene group. Reisine T, Pasternak G. Opioid analgesics and antagonists. In: Hardman JG, Limbird LE, Molinoff PB, Ruddon RW, Gilman AG, eds. Goodman and Gilman’s The Pharmacological Basis of Therape ...
2-16-17 PPT
... True OR False • A patient taking Cefdinir may experience a lowering of her INR due to the gut flora being altered. • The interaction of aspirin and warfarin is due to warfarin being displaced from protein binding sites causing an increased INR. • A chronic alcoholic can be expected to have consiste ...
... True OR False • A patient taking Cefdinir may experience a lowering of her INR due to the gut flora being altered. • The interaction of aspirin and warfarin is due to warfarin being displaced from protein binding sites causing an increased INR. • A chronic alcoholic can be expected to have consiste ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... pain. Pain is experienced as having qualities such as sharp, throbbing, dull, nauseating, burning and shooting. Pain receptors are free nerve endings. There are mechanical, thermal and chemical pain receptors. Nociceptor A and C fibers mediate fast and slow pain. Thin myelinated A fibers transmit si ...
... pain. Pain is experienced as having qualities such as sharp, throbbing, dull, nauseating, burning and shooting. Pain receptors are free nerve endings. There are mechanical, thermal and chemical pain receptors. Nociceptor A and C fibers mediate fast and slow pain. Thin myelinated A fibers transmit si ...
Quetiapine and extrapyramidal effects
... Literature and mechanism The older generation of antipsychotics is associated with extrapyramidal effects, because of their dopaminergic inhibition. The blockade of nigrostriatal dopamine tracts results in a relative increase in cholinergic activity. Atypical antipsychotics, like quetiapine, have du ...
... Literature and mechanism The older generation of antipsychotics is associated with extrapyramidal effects, because of their dopaminergic inhibition. The blockade of nigrostriatal dopamine tracts results in a relative increase in cholinergic activity. Atypical antipsychotics, like quetiapine, have du ...
section 1: treatment of depression
... Patients prescribed short half-life drugs (e.g. paroxetine); patients who have taken an antidepressant for more than 8 weeks; patients who developed anxiety at the start of antidepressant therapy (particularly SSRI’s); patients taking other centrally acting drugs (e.g. antihypertensives, antihistami ...
... Patients prescribed short half-life drugs (e.g. paroxetine); patients who have taken an antidepressant for more than 8 weeks; patients who developed anxiety at the start of antidepressant therapy (particularly SSRI’s); patients taking other centrally acting drugs (e.g. antihypertensives, antihistami ...
Neurobiological substrates for the dark side of compulsivity in
... a composite addiction cycle comprised of three stagesd preoccupation/anticipation, binge/intoxication, and withdrawal/ negative affectdwhere impulsivity often dominates at the early stages and compulsivity dominates at terminal stages. As an individual moves from impulsivity to compulsivity, a shift ...
... a composite addiction cycle comprised of three stagesd preoccupation/anticipation, binge/intoxication, and withdrawal/ negative affectdwhere impulsivity often dominates at the early stages and compulsivity dominates at terminal stages. As an individual moves from impulsivity to compulsivity, a shift ...
DANGERS OF PHARMACEUTICAL SUBSTITUTES FOR NICOTINE
... your nicotine fix, but at the higher cost because drugs are more expensive then cigarettes and you are still hooked! Furthermore the harmful effects of nicotine on the body continue. Nicotine Inhaler The Nicotrol® Inhaler (nicotine inhalation system) consists of a mouthpiece and plastic cartridges, ...
... your nicotine fix, but at the higher cost because drugs are more expensive then cigarettes and you are still hooked! Furthermore the harmful effects of nicotine on the body continue. Nicotine Inhaler The Nicotrol® Inhaler (nicotine inhalation system) consists of a mouthpiece and plastic cartridges, ...
Metabolic Syndrome
... • LV dysfunction (along with new blocker) • Previous MI (along with new blocker) ...
... • LV dysfunction (along with new blocker) • Previous MI (along with new blocker) ...
The diagnosis and management of benzodiazepine dependence Heather Ashton
... range of actions – sedative/hypnotic, anxiolytic, anticonvulsant and muscle relaxant – combined with low toxicity and alleged lack of dependence potential seemed to make them ideal medications for many common conditions (Table 1). The drugs were prescribed long term, often for many years, for compla ...
... range of actions – sedative/hypnotic, anxiolytic, anticonvulsant and muscle relaxant – combined with low toxicity and alleged lack of dependence potential seemed to make them ideal medications for many common conditions (Table 1). The drugs were prescribed long term, often for many years, for compla ...
Synergistic Interaction between Fentanyl and
... the advantage of reducing the dose that would be necessary if either drug were used alone, thus potentially decreasing the incidence and severity of associated side effects such as hypotension and motor block.1 However, the nature of the pharmacologic interaction between opioids and local anesthetic ...
... the advantage of reducing the dose that would be necessary if either drug were used alone, thus potentially decreasing the incidence and severity of associated side effects such as hypotension and motor block.1 However, the nature of the pharmacologic interaction between opioids and local anesthetic ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... The term seizure is derived from the latin word Sacire, ‘to take possession of’ .An epileptic seizure is a paroxysmal event due to abnormal excessive or synchronous neuronal activity in the brain. Depending upon the distribution of the discharges, this abnormal brain activity may have various manife ...
... The term seizure is derived from the latin word Sacire, ‘to take possession of’ .An epileptic seizure is a paroxysmal event due to abnormal excessive or synchronous neuronal activity in the brain. Depending upon the distribution of the discharges, this abnormal brain activity may have various manife ...
Diabetic Hypertension targetted Rx. by Dr. Sarma
... • LV dysfunction (along with new blocker) • Previous MI (along with new blocker) ...
... • LV dysfunction (along with new blocker) • Previous MI (along with new blocker) ...
The diagnosis and management of benzodiazepine dependence
... range of actions – sedative/hypnotic, anxiolytic, anticonvulsant and muscle relaxant – combined with low toxicity and alleged lack of dependence potential seemed to make them ideal medications for many common conditions (Table 1). The drugs were prescribed long term, often for many years, for compla ...
... range of actions – sedative/hypnotic, anxiolytic, anticonvulsant and muscle relaxant – combined with low toxicity and alleged lack of dependence potential seemed to make them ideal medications for many common conditions (Table 1). The drugs were prescribed long term, often for many years, for compla ...
MS_Word ~ 89 KB
... single 10 mg tablet. The intramuscular form has a bioavailability of 100% and a mean peak plasma concentration of 2.2 microgram/mL occurs an average of 50 minutes after a single 30 mg dose. Ketorolac is expensive, and its efficacy is no better than that of other orally or rectally administered NSAID ...
... single 10 mg tablet. The intramuscular form has a bioavailability of 100% and a mean peak plasma concentration of 2.2 microgram/mL occurs an average of 50 minutes after a single 30 mg dose. Ketorolac is expensive, and its efficacy is no better than that of other orally or rectally administered NSAID ...
... The K. vesicatoria extract was tested against two different drug-resistant strains of M. tuberculosis, which resulted in an MIC of 50.00 μg/mL on both strains. The combination of K. vesicatoria with INH exhibited the best synergistic antimycobacterial activity with a fractional inhibitory concentrati ...
Phenolphthalein Report on Carcinogens, Thirteenth Edition CAS No. 77-09-8
... population has been exposed to phenolphthalein through its common use as an over-the-counter drug, particularly as a laxative. The typical oral dose of phenolphthalein as an over-the-counter laxative was 30 to 200 mg for adults and children aged 12 years or older; the recommended dose was not to ex ...
... population has been exposed to phenolphthalein through its common use as an over-the-counter drug, particularly as a laxative. The typical oral dose of phenolphthalein as an over-the-counter laxative was 30 to 200 mg for adults and children aged 12 years or older; the recommended dose was not to ex ...
File - Ms. Walajtys` Pharmacy Tech Class Sidekick
... • Blocks reabsorption of GABA, allowing it to bind to nerve cells which enhances normal brain activity • Should be taken with food • Can cause seizures if patients who do not have epilepsy use it off-label ...
... • Blocks reabsorption of GABA, allowing it to bind to nerve cells which enhances normal brain activity • Should be taken with food • Can cause seizures if patients who do not have epilepsy use it off-label ...
Development of directly compressible metformin hydrochloride by
... typical example of this type of drugs. Metformin hydrochloride is an oral anti-hyperglycemic agent of the biguanide class used in the treatment of non-insulin dependent diabetes mellitus (2). Metformin hydrochloride is highly water soluble (> 300 mg mL–1 at 25 °C), hygroscopic and shows stability pr ...
... typical example of this type of drugs. Metformin hydrochloride is an oral anti-hyperglycemic agent of the biguanide class used in the treatment of non-insulin dependent diabetes mellitus (2). Metformin hydrochloride is highly water soluble (> 300 mg mL–1 at 25 °C), hygroscopic and shows stability pr ...
Dermatology Workshop
... • Combine a topical retinoid plus an antimicrobial • Limit the use of antibiotics to short periods and discontinue when there is no further improvement or the improvement is only slight • Co-prescribe a BPO-containing product or use as washout • Oral and topical antibiotics should not be used as mon ...
... • Combine a topical retinoid plus an antimicrobial • Limit the use of antibiotics to short periods and discontinue when there is no further improvement or the improvement is only slight • Co-prescribe a BPO-containing product or use as washout • Oral and topical antibiotics should not be used as mon ...
Opioid Prescribing Tool Kit
... prescribe any available opioid to treat any patient who suffers from pain. This still applies even if the patient has a drug addiction problem (although this is not always the best clinical course). However, physicians cannot prescribe any opioid for the maintenance treatment of addiction (even if t ...
... prescribe any available opioid to treat any patient who suffers from pain. This still applies even if the patient has a drug addiction problem (although this is not always the best clinical course). However, physicians cannot prescribe any opioid for the maintenance treatment of addiction (even if t ...