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Chapter 8
Chapter 8

... Stimulant Use and Abuse Cocaine and amphetamines are among the major stimulants abused in the U.S.  Cocaine comes in two forms: powder and crack  23 million people in U.S. over 12 years old have tried cocaine  Men more likely to use than women ...
generic prescribing - when not to do it!
generic prescribing - when not to do it!

... Generic Prescribing: When not to do to do it! Generic prescribing is generally more cost-effective than prescribing by brand name. There are some circumstances however in which it is preferable to prescribe by brand name. Some common examples are given below but note that this list is not exhaustive ...
Drug Discovery Pipeline Brief Report 2011
Drug Discovery Pipeline Brief Report 2011

... Rationale for the Approach: The major cause of resistance to Gleevec is a secondary mutation in the kinase domain of target gene expression products. Research indicates that the common point mutation sites related to Gleevec resistance include E255K, E255V, T315I and D276G of Bcr-Abl and D816 of c-K ...
Word file - SLT by Ellex
Word file - SLT by Ellex

... an option for most patients, but is especially suited for patients who cannot tolerate or are unable to self-administer glaucoma medications. Highly effective, SLT is used as primary treatment for early stages of open angle glaucoma, and can also be used in combination with drug therapy or as an alt ...
Antipsychotics in the Pipeline
Antipsychotics in the Pipeline

... contrary, the concept that plasma protein binding displacement is a common cause of clinically significant interactions may still be widely taught in some medical schools, often appears in textbooks and is accepted by many in the medical community and by drug regulators.” Sansom LN & Evans AM. Drug ...
Phases of Drug Action
Phases of Drug Action

... • This is the time required for the concentration of drug in the blood to decrease by 50%. • Half-life affects the frequency of administration • Drugs with short half-lives are quickly eliminated from the body. ( Ex: PCN given several X per day ) • Drugs with longer half-lives stay in the body longe ...
User`s ​​​Guide - BC Cancer Agency
User`s ​​​Guide - BC Cancer Agency

... Interim monographs are provided for parenteral non-benefit antineoplastic drugs which are made available at BCCA through the BCCA Compassionate Access Program, including drugs which are not yet marketed in Canada and are accessible through the Health Canada Special Access Program. Drug information i ...
Acetaminophen
Acetaminophen

... Advise patient: • to abstain from alcohol while taking this medication. • to report signs of liver dysfunction including jaundice, itching, fatigue. *Monitor renal function tests and intake and Advise patient: output (due to the ability of acetaminophen to • that lab tests to assess renal function m ...
Adverse Effects of Antibiotics
Adverse Effects of Antibiotics

... End-of Treatment ...
TB Review (Click Here)
TB Review (Click Here)

... The boundaries and names shown and the designations used on this map do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its fro ...
Ototoxic Medications
Ototoxic Medications

... (Antifungal preparations) • capreomycin (Capestat) (Anti-tuberculosis medication) ...
prodrug concept PPT
prodrug concept PPT

... 2. Cyclophosphamide does not possess alkylating properties and consequently is not a tissue vesicant ...
presentation
presentation

... Signs that US, EU citizens increasing demand for cheaper drugs Online pharmacies, Obama 2014 proposed budget Stories of cancer patients in Greece, AIDS patients in Spain unable to afford treatments Switzerland recently announced deal with pharma industry to reduce drug prices in return for faster ap ...
What are some other side effects of this drug?
What are some other side effects of this drug?

... What do I need to tell my doctor BEFORE I take this drug? • If you have an allergy to levodopa, carbidopa, or any other part of this drug. • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like ra ...
The common drugs of abuse in Hong Kong
The common drugs of abuse in Hong Kong

... GHB (Liquid Ecstasy) Gamma Hydroxybutyrate (GHB) was originally synthesized in 1960 as an anesthetic agent.22 It was not widely used because of its poor analgesic properties and seizure-like EEG pattern.23 It became popular with the bodybuilder in the 1980s for its ability to improve sleep and induc ...
Spinout Equinox Pharma speeds up and reduces the cost of drug
Spinout Equinox Pharma speeds up and reduces the cost of drug

... Existing high-throughput conventional screening is expensive and limited to a few compounds at a time. Computer-based virtual screening does not have these limitations, but not all in silico approaches are as effective as the one developed by Equinox. Some only achieve a 15% (or lower) hit rate, whe ...
Lysergic Acid Diethylamide (LSD)
Lysergic Acid Diethylamide (LSD)

... that is so strong that a single flake can cause actions similar to mental illness. There are many factors involved in the effects hallucinogens will have. For example, the size of the dose, emotional state of mind of the user, and the surroundings all play a role in determining whether the user has ...
Sick Day Medications In the Elderly
Sick Day Medications In the Elderly

... • Stopping may be justified due to short life expectancy, low risk of CV event, adverse effects, falling • PROSPER study was done with subjects aged 7082 with either history of CV disease and stroke or risk factors for same. Showed decreases in Coronary death, and non fatal MIs at 3 years ...
It`s not just marijuana anymore: A review of illicit drugs. Ahna Brutlag
It`s not just marijuana anymore: A review of illicit drugs. Ahna Brutlag

... forms—powder or crystal. The white powdered product (cocaine HCl) is commonly called “coke,” “C” or “blow” and is usually insufflated (snorted) or dissolved and injected IV. Cocaine can be further processed into the free alkaloid form (“free base”) often referred to as “crack”. “Crack” is a purer, m ...
the toxic family & addiction - MI-PTE
the toxic family & addiction - MI-PTE

... benzodiazepines (e.g., diazepam, alprazolam, clonazepam, and lorazepam) 100,784 drug abuse cases in 2002 opioid pain relievers (e.g., oxycodone, hydrocodone, morphine, methadone, and combinations that include these drugs). 119,000 Taken due to Drug addiction and desired psychoactive effects ...
lec#8 done by Ghaida`a Abuzahra and Nahla
lec#8 done by Ghaida`a Abuzahra and Nahla

... Potency is the strength of the drug. It’s a term that is used whenever we compare the dose of two drugs from the same category or the same class. NOTE: Potency is comparable only for drugs within the same class. As an example, we can’t compare the potency for Beta blockers with calcium channel bloc ...
December 2016
December 2016

... Xanax Abuse on the Rise Xanax is the most popular psychiatric drug on the market. It’s also one of the most abused. In the United States, doctors write nearly 50 million prescriptions for Xanax every year. That’s more than one prescription written every second. Xanax is in a class of drugs called be ...
Drugs for Gastrointestinal Disorders Duodenal Ulcer Gastric Ulcers
Drugs for Gastrointestinal Disorders Duodenal Ulcer Gastric Ulcers

... If erosion progresses deeper into the mucosa, bleeding will occur Many duodenal ulcers heal spontaneously Most frequent in the 30- to 50-year-old age group ...
Vol. 8, No. 3, March 2012 “Happy Trials to You” Adverse Event and
Vol. 8, No. 3, March 2012 “Happy Trials to You” Adverse Event and

... In addition to an ATC Classification and Drug Code, the Uppsala Monitoring Centre also assigns a unique Medicinal Product ID (MP_ID) to each medicinal product. For example, the Medicinal Product ID of Zomig is 64641, when marketed (by AstraZeneca) in Denmark and consisting of 2.5 mg of zolmitriptan ...
DRUG RECEPTORS AND PHARMACODYNAMICS
DRUG RECEPTORS AND PHARMACODYNAMICS

...  Receptors have a life cycle (as other proteins do). Receptors can be modified in numbers (long-term regulation) and in sensitivity. – Receptors can up-regulate: increase in numbers (chronic absence of agonist) – Down-regulate: decrease in numbers (chronic presence of ...
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