INHIBITOR of BACTERIAL PROTEIN SYNTHESIS
... • They are important drugs for the treatment of serious infections caused by aerobic gr(-) bacteria • When used alone they are not reliably effective in the treatment of gr(+) cocci • Antibacterial synergy may occur with the combination of wall synthesis inhibitors • Streptomycintuberculosis • Spec ...
... • They are important drugs for the treatment of serious infections caused by aerobic gr(-) bacteria • When used alone they are not reliably effective in the treatment of gr(+) cocci • Antibacterial synergy may occur with the combination of wall synthesis inhibitors • Streptomycintuberculosis • Spec ...
Drug Discovery 3
... Screening synthetic banks • Pharmaceutical companies have prepared thousands of compounds • These are stored (in the freezer!), cataloged and screened on new targets as these new targets are identified ...
... Screening synthetic banks • Pharmaceutical companies have prepared thousands of compounds • These are stored (in the freezer!), cataloged and screened on new targets as these new targets are identified ...
New Trends in Substance Abuse Youth Substance Abuse
... especially motivation and emotions. The ways in which the nerve cells communicate are changed because of damage to neurotransmitters and to the shapes of brain cells. The damage alters the way people behave. Drug interaction poses another risk. If the physician or pharmacist is not aware of everythi ...
... especially motivation and emotions. The ways in which the nerve cells communicate are changed because of damage to neurotransmitters and to the shapes of brain cells. The damage alters the way people behave. Drug interaction poses another risk. If the physician or pharmacist is not aware of everythi ...
Management of Parkinson`s Disease
... starting in one arm) with bradykinesia (slowing of movement) and rigidity (which may manifest as cogwheel rigidity particularly in the arms). Patients often display a generalised lack of movement both in terms of facial expression and general body movement. They often have reduced arm swing (usually ...
... starting in one arm) with bradykinesia (slowing of movement) and rigidity (which may manifest as cogwheel rigidity particularly in the arms). Patients often display a generalised lack of movement both in terms of facial expression and general body movement. They often have reduced arm swing (usually ...
PENICILLIN G
... Use higher than standard doses in Group B Strep (GBS) infections. Use Benzathine Pen G or Procaine Pen G for gonococci or asymptomatic congenital syphilis. ...
... Use higher than standard doses in Group B Strep (GBS) infections. Use Benzathine Pen G or Procaine Pen G for gonococci or asymptomatic congenital syphilis. ...
Important side effects to be considered when choosing antipsychotic
... Other effects: Blockade of -adrenergic receptors causes orthostatic hypotension and light-headedness. The neuroleptics also alter temperature-regulating mechanisms and can produce poikilothermia (body temperature varies with the environment). In the pituitary, neuroleptics block D2 receptors, lea ...
... Other effects: Blockade of -adrenergic receptors causes orthostatic hypotension and light-headedness. The neuroleptics also alter temperature-regulating mechanisms and can produce poikilothermia (body temperature varies with the environment). In the pituitary, neuroleptics block D2 receptors, lea ...
DRUGS THAT AFFECT CARDIOVASCULAR FUNCTIONS
... feedback inhibition of noradrenaline release is maintained resulting in antihypertensive effect making the drug antihypertensive drug, • Phentolamine is a non-selective α-adrenoceptor antagonist, and directly cause vasodilation and cardiac inotropic action. It is used for management of adrenergic hy ...
... feedback inhibition of noradrenaline release is maintained resulting in antihypertensive effect making the drug antihypertensive drug, • Phentolamine is a non-selective α-adrenoceptor antagonist, and directly cause vasodilation and cardiac inotropic action. It is used for management of adrenergic hy ...
Introduction to Drugs and Pharmacy
... • (5) FDA Drug Classification system • Upon receipt and examination of an IND or NDA, the FDA classifies the drug by chemical type and therapeutic potential. Page 49 • (6) Phases of a Clinical Investigation • An IND may be submitted for one or more phases of a clinical investigation,namely Phase 1, ...
... • (5) FDA Drug Classification system • Upon receipt and examination of an IND or NDA, the FDA classifies the drug by chemical type and therapeutic potential. Page 49 • (6) Phases of a Clinical Investigation • An IND may be submitted for one or more phases of a clinical investigation,namely Phase 1, ...
drugs that affect cardiovascular system
... feedback inhibition of noradrenaline release is maintained resulting in antihypertensive effect making the drug antihypertensive drug, • Phentolamine is a non-selective α-adrenoceptor antagonist, and directly cause vasodilation and cardiac inotropic action. It is used for management of adrenergic hy ...
... feedback inhibition of noradrenaline release is maintained resulting in antihypertensive effect making the drug antihypertensive drug, • Phentolamine is a non-selective α-adrenoceptor antagonist, and directly cause vasodilation and cardiac inotropic action. It is used for management of adrenergic hy ...
Local Anaesthesia
... Vascularity of the tissues. The route of administration. The presence of vasoconstrictor. ...
... Vascularity of the tissues. The route of administration. The presence of vasoconstrictor. ...
Injectable Anesthetics
... Passes into the brain cells more quickly=faster onset of action High solubility results in rapid tissue redistribution Short-acting drugs are moderately lipid solublemetabolized by the liver – takes longer then redistribution Long-acting drugs have low lipid solubility- excreted primarily thro ...
... Passes into the brain cells more quickly=faster onset of action High solubility results in rapid tissue redistribution Short-acting drugs are moderately lipid solublemetabolized by the liver – takes longer then redistribution Long-acting drugs have low lipid solubility- excreted primarily thro ...
1B Ulcer Medicines
... 1920's surge in use because also a syphilis treatment Use rebounded in 1980's: Peptic ulcer patients have larger than normal amounts of BACTERIUM ‘Helicobacter pylori’ (H. pylori), especially type O blood, where bacterium links to stomach wall via a sugar. Bismuth salts(*) inhibit this linking, and ...
... 1920's surge in use because also a syphilis treatment Use rebounded in 1980's: Peptic ulcer patients have larger than normal amounts of BACTERIUM ‘Helicobacter pylori’ (H. pylori), especially type O blood, where bacterium links to stomach wall via a sugar. Bismuth salts(*) inhibit this linking, and ...
Titrimetric and Spectrophotometric Determinations of
... reliability of the assay methods was established by parallel determination by the BP method. ...
... reliability of the assay methods was established by parallel determination by the BP method. ...
Nimulid Tablet - Panacea Biotec
... developing a GI bleed than patients with neither of these risk factors. In addition to a past history of ulcer disease, pharmaco-epidemiological studies have identified several other co-therapies or co-morbid conditions that may increase the risk for GI bleeding such as: treatment with oral corticos ...
... developing a GI bleed than patients with neither of these risk factors. In addition to a past history of ulcer disease, pharmaco-epidemiological studies have identified several other co-therapies or co-morbid conditions that may increase the risk for GI bleeding such as: treatment with oral corticos ...
Ecstasy and Club Drugs
... considered to be the most commonly used club (or “designer” drug). Ecstasy is an illegal drug (it was declared illegal by the federal government in 1985) 90% of which is manufactured in the Netherlands and Belgium. In its most common form, Ecstasy is a small tablet that is impressed with any one of ...
... considered to be the most commonly used club (or “designer” drug). Ecstasy is an illegal drug (it was declared illegal by the federal government in 1985) 90% of which is manufactured in the Netherlands and Belgium. In its most common form, Ecstasy is a small tablet that is impressed with any one of ...
GI system - WEB БАЗИРАНО ОБУЧЕНИЕ ПО
... Treatment of infective diarrhoeas needs proper diagnosis and suitable antibiotic and/or antiprotozoal drug. For symptomatic relief of non-specific diarrhoes are used: (1) Antimotility and Antisecretory Agents a) Opioid agonists which does not cross BBB • Loperamide (Imodium®) and Racecadotril (Hidr ...
... Treatment of infective diarrhoeas needs proper diagnosis and suitable antibiotic and/or antiprotozoal drug. For symptomatic relief of non-specific diarrhoes are used: (1) Antimotility and Antisecretory Agents a) Opioid agonists which does not cross BBB • Loperamide (Imodium®) and Racecadotril (Hidr ...
Table of Antidotes (Word Document, 20kB)
... Amyl nitrite is the first step in a three-step treatment protocol for cyanide poisoning. After the administration of amyl nitrite, administer sodium nitrite, followed by sodium thiosulfate The duration of action of naloxone is shorter than that of narcotics. Therfore, repeat dose of naloxone may be ...
... Amyl nitrite is the first step in a three-step treatment protocol for cyanide poisoning. After the administration of amyl nitrite, administer sodium nitrite, followed by sodium thiosulfate The duration of action of naloxone is shorter than that of narcotics. Therfore, repeat dose of naloxone may be ...
CYP2D6 - PGXL Laboratories
... CYP2C19 Poor Metabolizer (PM): This patient’s genotype is consistent with significantly reduced CYP2C19 enzymatic activity. PMs are at increased risk of drug-induced side effects due to diminished drug elimination of active drugs. Patients with no CYP2C19 function (PMs) taking clopidogrel lack adequ ...
... CYP2C19 Poor Metabolizer (PM): This patient’s genotype is consistent with significantly reduced CYP2C19 enzymatic activity. PMs are at increased risk of drug-induced side effects due to diminished drug elimination of active drugs. Patients with no CYP2C19 function (PMs) taking clopidogrel lack adequ ...
The Pharmaceutical Industry Presented to Geoffrey Poitras Bus 417
... NDA contains data supporting the efficacy and safety of the drug Approval can take 2 month to several years, but on average, it takes around 18 to 24 months Drugs are subject to ongoing review, making sure no adverse side effects appear from the drug. After FDA’s approval, the drug can be marketed a ...
... NDA contains data supporting the efficacy and safety of the drug Approval can take 2 month to several years, but on average, it takes around 18 to 24 months Drugs are subject to ongoing review, making sure no adverse side effects appear from the drug. After FDA’s approval, the drug can be marketed a ...
Lecture 5
... Some of the ____________________________________ (the parts that they break down into) are active substances that can cause more effects Tolerance Typically develops as the liver becomes better at processing the drug ____________________________________reverse tolerance Older people need less of the ...
... Some of the ____________________________________ (the parts that they break down into) are active substances that can cause more effects Tolerance Typically develops as the liver becomes better at processing the drug ____________________________________reverse tolerance Older people need less of the ...
Patients Perspective Towards Mail Order Services
... Current Place in Therapy • FDA approved as adjunct to diet and exercise to control blood glucose. • Also studied in combination with metformin, SU, insulin, pioglitazone • Can be used as second line, after metformin ( because metformin is more studied and approved as first line), however, its cost ...
... Current Place in Therapy • FDA approved as adjunct to diet and exercise to control blood glucose. • Also studied in combination with metformin, SU, insulin, pioglitazone • Can be used as second line, after metformin ( because metformin is more studied and approved as first line), however, its cost ...
Centrally Acting Agents
... Clonidine can cause sedation and drowsiness, dry mouth and sexual dysfunction in men. In addition, this agent is associated with rapid rebound in hypertension on abrupt cessation of high doses presumably as a consequence of receptor up-regulation. ...
... Clonidine can cause sedation and drowsiness, dry mouth and sexual dysfunction in men. In addition, this agent is associated with rapid rebound in hypertension on abrupt cessation of high doses presumably as a consequence of receptor up-regulation. ...
H2 antagonists and proton pumb inhibitors (1435 H).
... Which one (s) produce (s) constipation? AL (OH)3 Which one (s) produce (s) diarrhea? Mg (OH)2 Which one is used for Rx metabolic acidosis? Ca CO3 Why their uses have been declined in peptic Ulcer? ...
... Which one (s) produce (s) constipation? AL (OH)3 Which one (s) produce (s) diarrhea? Mg (OH)2 Which one is used for Rx metabolic acidosis? Ca CO3 Why their uses have been declined in peptic Ulcer? ...
Technical Paper III - Pharmacy - Bhutan Civil Service Examinations
... 3. What are the signs and symptoms of seizures? What type of seizure is consistent with Dema’s symptoms? (7) 4. Comment on the pharmacological management of epilepsy. What is the mode of action of valproate and what side effects are associated with its use? (10) 5. Give three examples of drugs recom ...
... 3. What are the signs and symptoms of seizures? What type of seizure is consistent with Dema’s symptoms? (7) 4. Comment on the pharmacological management of epilepsy. What is the mode of action of valproate and what side effects are associated with its use? (10) 5. Give three examples of drugs recom ...
Predicting new molecular targets for known drugs
... Although drugs are intended to be selective, at least some bind to several physiological targets, explaining side effects and efficacy. Because many drug–target combinations exist, it would be useful to explore possible interactions computationally. Here we compared 3,665 US Food and Drug Administra ...
... Although drugs are intended to be selective, at least some bind to several physiological targets, explaining side effects and efficacy. Because many drug–target combinations exist, it would be useful to explore possible interactions computationally. Here we compared 3,665 US Food and Drug Administra ...