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Breakthrough Seizures—Approach to Prevention
Breakthrough Seizures—Approach to Prevention

... association between periods of non-adherence and significantly higher incidence of visits to emergency departments, hospitalizations, fractures, and injuries related to motor vehicle accidents compared with periods of adherence. Furthermore, patients non-adherent to AEDs exhibited a threefold increa ...
A. Treating acute gout
A. Treating acute gout

... treated with indomethacin to decrease movement of granulocytes into the affected area; NSAIDs other than indomethacin are also effective at decreasing pain and inflammation. [Note: Aspirin is contraindicated, because it competes with uric acid for the organic acid secretion mechanism in the proximal ...
Certified Medication Technician Student Manual
Certified Medication Technician Student Manual

... body. While it is in the body the drug can act either locally or systemically. In order to safely administer medications in a long term care setting, the medication technician must have an understanding of basic pharmacology including the steps in the drug cycle, drug effects, and how drugs are clas ...
Schizophrenia II - Psychiatry Training
Schizophrenia II - Psychiatry Training

... • Atypical antipsychotic drugs – clozapine: antipsychotic without associated EPS or increases in serum prolactin; active at low levels of D2 occupancy (<60%) – “atypical” term later expanded to include its unique activity in treating treatmentresistant patients – newer atypicals (quetiapine, olanzap ...
Current Concepts in Antiretroviral Therapy Failure - IAS-USA
Current Concepts in Antiretroviral Therapy Failure - IAS-USA

... being greater in patients in whom optimal PI concentrations were maintained than in those who had suboptimal concentrations and a regimen selected via genotyping. The greatest decreases occurred in patients with optimized PI levels and genotypic test results. Some retrospective studies have shown a ...
Reactive Metabolites - New England Drug Metabolism Discussion
Reactive Metabolites - New England Drug Metabolism Discussion

... • Unrelated to primary pharmacology • Dose independent (with the exception of some drugs) – can occur at any dose within the therapeutic range • Temporal relationship - Symptoms subsides after cessation of treatment; rapid onset upon re-challenge • Can be severe - maybe fatal - most common cause for ...
Antibiotics in Endodontics
Antibiotics in Endodontics

...  Patient’s health. Is the patient in good health? If not, it is more likely that antibiotics will be needed.  Development of symptoms: How rapidly did the symptoms occur? Swelling or fever that escalates within a 24-to 72- hour period may indicate that an infection is spreading, and antibiotics ar ...
Metabolic Activation and Idiosycratic Drug Toxicity
Metabolic Activation and Idiosycratic Drug Toxicity

... •  Unrelated to primary pharmacology •  Dose independent (with the exception of some drugs) – can occur at any dose within the therapeutic range •  Temporal relationship - Symptoms subsides after cessation of treatment; rapid onset upon re-challenge •  Can be severe - maybe fatal - most common cause ...
Supplemental Table 2. 2015 American Geriatrics Society Beers
Supplemental Table 2. 2015 American Geriatrics Society Beers

... benign prostatic antimuscarinic for retention hyperplasia urinary incontinence (see Table 7 in full criteria available on www.geriatricscareonli ne.org). The primary target audience is the practicing clinician. The intentions of the criteria include 1) improving the selection of prescription drugs b ...
Cognitive therapies
Cognitive therapies

... • Drugs used to control anxiety and agitation • Depress central nervous system activity • Calm anxiety as person learns to cope with fear-triggering stimuli • Made reduce symptoms without resolving underlying problems ...
OL Chapter 13 - NSCC NetID: Personal Web Space
OL Chapter 13 - NSCC NetID: Personal Web Space

... • Drugs used to control anxiety and agitation • Depress central nervous system activity • Calm anxiety as person learns to cope with fear-triggering stimuli • Made reduce symptoms without resolving underlying problems ...
8: Malignant disease and immunosuppression
8: Malignant disease and immunosuppression

... http://www.ncn.nhs.uk/hpSite/groups/networkcrosscuttinggroups/chemotherapy This handbook lists all the approved chemotherapy protocols, which contain details of prescribing issues, management of toxic effects and supportive care. When oral cytotoxic drugs are used for the treatment of malignant dise ...
Cognitive therapies
Cognitive therapies

... • Drugs used to control anxiety and agitation • Depress central nervous system activity • Calm anxiety as person learns to cope with fear-triggering stimuli • Made reduce symptoms without resolving underlying problems ...
Therapeutic Drug Monitoring (TDM)
Therapeutic Drug Monitoring (TDM)

... dosage must, therefore, be adjusted on the basis of the plasma lithium concentration 6–12 hours post-dose. The plasma lithium should then be monitored 3–4 monthly to ensure that dosage is still optimal.3 As indicated above a very important general point in TDM is the time the sample is taken in rela ...
March 06, 2014 Meeting Summary - Posted 03/24/2014
March 06, 2014 Meeting Summary - Posted 03/24/2014

... Dr. Linda Catanzaro presented a report on Hepatitis C Virus clinical criteria that discussed the place in therapy for the new medications, simeprevir (Olysio) and sofosbuvir (Sovaldi). Their place in therapy and monitoring required for use of these medications were considered. The Medicaid FFS clini ...
Epilepsy - Back to Medical School
Epilepsy - Back to Medical School

... ADR other drugs Social aspects ...
Profile of female patients seeking in-patient treatment for
Profile of female patients seeking in-patient treatment for

... disorders has been reported to be high among women abusing prescription opioids. More specifically, the association between depressive and anxiety disorders and abuse of prescription opioids among women has been supported in earlier studies from west6,7. Choice of psychoactive substance, reasons for ...
Drugs of Abuse - EMS Update 2017
Drugs of Abuse - EMS Update 2017

... Synthesized for treatment of pain/nausea Hard to separate psychoactive effects Many have been developed – HU-210 – CP series (i.e., CP-47,497) – J.W. Huffman (i.e., JWH 018) ...
Benzodiazepine Pharmacology and Central Nervous System
Benzodiazepine Pharmacology and Central Nervous System

... generally necessary for an agent to be eliminated from the body, making the number of hours that a drug is in the body considerably longer. The table lists various BZDs and their characteristics.2 Another way to characterize BZDs is by relative potency. The first BZDs were low to medium potency. The ...
Once-Daily Aptiom ® (eslicarbazepine acetate)
Once-Daily Aptiom ® (eslicarbazepine acetate)

... (eslicarbazepine acetate), a once-daily antiepileptic drug (AED) indicated for use as adjunctive treatment of partial-onset seizures, is now available by prescription in pharmacies across the United States. APTIOM, a voltage-gated sodium channel blocker, is a new chemical entity approved by the U.S. ...
PDF (Injection of synthetic cathinones)
PDF (Injection of synthetic cathinones)

... Helsinki area. Of a sample of 100 ‘marginalised drug users’, 54 reported using MDPV in the past year and of these 96 % had injected the drug (Tammi et al., 2011). There is additional limited data on the use of cathinones or more generally of NPS by people who inject drugs, but where the route of adm ...
PHARMACEUTICAL STUDIES ON FLASH TABLETS OFA HIGHLY SOLUBLE METFORMIN HYDROCHLORIDE
PHARMACEUTICAL STUDIES ON FLASH TABLETS OFA HIGHLY SOLUBLE METFORMIN HYDROCHLORIDE

... Metformin is a biguanide type insulin sensitizing drug used to treat type-2 diabetes [1]. It is used in drug discovery in vivo models to assess the anti-diabetic potential of other drugs. Metformin became commercially available in 1957.Therapeutic doses of metformin do not produce hypoglycemia, and ...
Review notes
Review notes

... pH, but becomes insoluble and forms precipitates at neutral pH after SC administration long lasting (similar to Lente) ...
Managing the Treatment
Managing the Treatment

... either initiation or dose adjustments of insulin or oral hypoglycemic agents for treatment of these events. In some cases, diabetic ketoacidosis has occurred. In those patients who discontinued protease inhibitor therapy, hyperglycemia persisted in some cases. Because these events have been reported ...
Hallucinogens
Hallucinogens

... MDMA and amphetamine) act on the synapse to increase the activity of dopamine, noradrenaline and serotonin. ...
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