ISHIK UNIVERSITY FACULTY OF DENTISTRY
... The pKa for most local anesthetics is in the range of 8.0-9.0. A balance of charged and uncharged forms is present in the body. The ratio between the cationic and uncharged forms of these drugs is determined by the HendersonHasselbalch equation (Log (cationic form/uncharged form) = pKa-pH). The unch ...
... The pKa for most local anesthetics is in the range of 8.0-9.0. A balance of charged and uncharged forms is present in the body. The ratio between the cationic and uncharged forms of these drugs is determined by the HendersonHasselbalch equation (Log (cationic form/uncharged form) = pKa-pH). The unch ...
Eating Disorders Leaflet
... Eating Disorders are common in young people. Anorexia usually starts in early adolescence and children as young as seven could have the illness. Bulimia starts in late adolescence. ...
... Eating Disorders are common in young people. Anorexia usually starts in early adolescence and children as young as seven could have the illness. Bulimia starts in late adolescence. ...
11/5/2014 Cannabinoids Activate CB Receptors
... CB1 and CB2 subtypes identified to‐date; potentially additional receptors exist Involved in appetite, mood, pain sensation and memory Present on cells in brain that repress neurotransmitter release, as well as peripheral cells ...
... CB1 and CB2 subtypes identified to‐date; potentially additional receptors exist Involved in appetite, mood, pain sensation and memory Present on cells in brain that repress neurotransmitter release, as well as peripheral cells ...
Lexical Plasticity in Early Bilinguals Does Not Alter Phoneme
... neurons, organized in functional populations (henceforth, pools), whose interactions can account for the behavior observed. We propose two competing network architectures, each representing a specific cognitive hypothesis. One model supposes an interaction at the phonemic level as the main mechanism ...
... neurons, organized in functional populations (henceforth, pools), whose interactions can account for the behavior observed. We propose two competing network architectures, each representing a specific cognitive hypothesis. One model supposes an interaction at the phonemic level as the main mechanism ...
Ascending Sensory Pathways
... medial lemniscus) relays discriminative (fine) tactile sense, vibratory sense, and position sense (Table 10.1). The somatosensory pathways to the cerebellum, which include the anterior, posterior, and rostral spinocerebellar, as well as the cuneocerebellar tracts, relay primarily proprioceptive (but ...
... medial lemniscus) relays discriminative (fine) tactile sense, vibratory sense, and position sense (Table 10.1). The somatosensory pathways to the cerebellum, which include the anterior, posterior, and rostral spinocerebellar, as well as the cuneocerebellar tracts, relay primarily proprioceptive (but ...
PDF+Links
... 1996; Castel-Barthe et al., 1996), suggesting that age-related pathological brain dysfunction might be ameliorated by treatment with neurotrophic factor. Most of earlier studies usually estimated degenerative or atrophic changes in morphology of the cholinergic neurons. However, recently attention h ...
... 1996; Castel-Barthe et al., 1996), suggesting that age-related pathological brain dysfunction might be ameliorated by treatment with neurotrophic factor. Most of earlier studies usually estimated degenerative or atrophic changes in morphology of the cholinergic neurons. However, recently attention h ...
Sherman_PPT_Chapter2
... • The parasympathetic nervous system slows the processes that have been accelerated by activation of the sympathetic nervous system. • These effects return the body to a more normal or balanced state of functioning characterized by an optimal range of physiological processes called homeostasis. Copy ...
... • The parasympathetic nervous system slows the processes that have been accelerated by activation of the sympathetic nervous system. • These effects return the body to a more normal or balanced state of functioning characterized by an optimal range of physiological processes called homeostasis. Copy ...
Microconnectomics of the Pretectum and Ventral Thalamus in the
... Crossland and Uchwat, 1979; Vega-Zuniga et al., 2014). Although the role of the GLv is still unclear, it has been implicated in optokinetic reflex modulation and head and eye orienting movements (Pateromichelakis, 1979; Guiloff et al., 1987; Gioanni et al., 1991). Apart from these general studies, d ...
... Crossland and Uchwat, 1979; Vega-Zuniga et al., 2014). Although the role of the GLv is still unclear, it has been implicated in optokinetic reflex modulation and head and eye orienting movements (Pateromichelakis, 1979; Guiloff et al., 1987; Gioanni et al., 1991). Apart from these general studies, d ...
Phenylketonuria (PKU)
... Prenatal diagnosis is done by detecting gene mutation in fetus Neonatal diagnosis in infants is done by measuring blood phe levels Treatment: Life ...
... Prenatal diagnosis is done by detecting gene mutation in fetus Neonatal diagnosis in infants is done by measuring blood phe levels Treatment: Life ...
SPINAL CORD II
... Contralateral loss of pain and temperature sensation below the level of lesion ...
... Contralateral loss of pain and temperature sensation below the level of lesion ...
A Fast, Reciprocal Pathway between the Lateral Geniculate Nucleus
... collision trials (red traces). In a collision trial, a spontaneous spike from the recorded cortical neuron triggers the electrical shock. If the neuron is a GR neuron that receives feedforward input from the LGN, then the spontaneous spike will not affect the propagation of the orthodromic spike and ...
... collision trials (red traces). In a collision trial, a spontaneous spike from the recorded cortical neuron triggers the electrical shock. If the neuron is a GR neuron that receives feedforward input from the LGN, then the spontaneous spike will not affect the propagation of the orthodromic spike and ...
Biosynthesis of Amino Acids
... carbon skeletons come from intermediates of glycolysis, the pentose phosphate pathway and the citric acid cycle. On the basis of the starting points the 20 amino acids can be group into 6 categories depending on the precursor: oxaloacetate, PEP, α-ketoglutarate, pyruvate, 3-phosphoglycerate, ribose- ...
... carbon skeletons come from intermediates of glycolysis, the pentose phosphate pathway and the citric acid cycle. On the basis of the starting points the 20 amino acids can be group into 6 categories depending on the precursor: oxaloacetate, PEP, α-ketoglutarate, pyruvate, 3-phosphoglycerate, ribose- ...
Evolution of Nervous Systems and Brains
... many features of nerve cells such as membrane potential, transmitters and other neuroactive substances, membrane receptors, ion channels, many chemical processes relevant for “neuronal information processing”, and even action potentials – all of which being more than 1 billion years old and thus old ...
... many features of nerve cells such as membrane potential, transmitters and other neuroactive substances, membrane receptors, ion channels, many chemical processes relevant for “neuronal information processing”, and even action potentials – all of which being more than 1 billion years old and thus old ...
Controlling subcellular delivery to optimize
... led Gunter Blobel to win a Nobel Prize [1–3] . Blobel predicted that ‘zip codes’ were responsible for targeting certain proteins to subcellular compartments such as the cytoplasm, nucleus, nucleolus, mitochondria, endoplasmic reticulum (ER), Golgi and peroxisomes (Figure 1) . The intracellular deli ...
... led Gunter Blobel to win a Nobel Prize [1–3] . Blobel predicted that ‘zip codes’ were responsible for targeting certain proteins to subcellular compartments such as the cytoplasm, nucleus, nucleolus, mitochondria, endoplasmic reticulum (ER), Golgi and peroxisomes (Figure 1) . The intracellular deli ...
as NT
... Monoamine NT do not directly open ion channels. Act through second messenger, such as cAMP. Binding of norepinephrine stimulates dissociation of Gprotein alpha subunit. Alpha subunit binds to adenylate cyclase, converting ATP to cAMP. cAMP activates protein kinase, phosphorylating other proteins. Op ...
... Monoamine NT do not directly open ion channels. Act through second messenger, such as cAMP. Binding of norepinephrine stimulates dissociation of Gprotein alpha subunit. Alpha subunit binds to adenylate cyclase, converting ATP to cAMP. cAMP activates protein kinase, phosphorylating other proteins. Op ...
Article Conserved Higher-Order Chromatin Regulates NMDA Receptor Gene Expression and Cognition Neuron
... binding around the distal arm of GRIN2BTSS+449kb (Figures 2A, S1A, and S1B). CTCF and associated proteins function as insulators and anchors for promoter-enhancer interactions and often bind to sequences in direct proximity and overlap with enhancer elements (Ghavi-Helm et al., 2014). Using 3C-ChIPl ...
... binding around the distal arm of GRIN2BTSS+449kb (Figures 2A, S1A, and S1B). CTCF and associated proteins function as insulators and anchors for promoter-enhancer interactions and often bind to sequences in direct proximity and overlap with enhancer elements (Ghavi-Helm et al., 2014). Using 3C-ChIPl ...
Nutrient Profile of Renal Specific Formula
... Kelly is also a Registered Nutritionist (RNutr.) through the Association for Nutrition in the UK. Prior to joining Abbott Nutrition, Dr. Kelly worked as an Assistant Professor at Texas Woman’s University where he lectured to dietetic and nursing students. Currently a Research Scientist in Abbott Nut ...
... Kelly is also a Registered Nutritionist (RNutr.) through the Association for Nutrition in the UK. Prior to joining Abbott Nutrition, Dr. Kelly worked as an Assistant Professor at Texas Woman’s University where he lectured to dietetic and nursing students. Currently a Research Scientist in Abbott Nut ...
Vibration Sensitivity and a Computational Theory for Prey
... source is calculated up to 20 cm distance. By ablating slit sensilla in various combinations on the eight legs, the contribution each makes in computing target location can be assessed. Other behavioral experiments show that differential timing of surface wave arrival at each sensor is most likely t ...
... source is calculated up to 20 cm distance. By ablating slit sensilla in various combinations on the eight legs, the contribution each makes in computing target location can be assessed. Other behavioral experiments show that differential timing of surface wave arrival at each sensor is most likely t ...
Altered Fronto-Striatal and Fronto-Cerebellar Circuits in Heroin
... upon which normal brain functions is primarily dependent [18], these researches mentioned above are all characterized with separately or isolatedly focusing on the effects of CHU either on regional brain activity or on a set of brain regions within a network. So, it is still difficult to generalize ...
... upon which normal brain functions is primarily dependent [18], these researches mentioned above are all characterized with separately or isolatedly focusing on the effects of CHU either on regional brain activity or on a set of brain regions within a network. So, it is still difficult to generalize ...
Causes, Diagnosis, and Treatment of Extravasation
... occurs as a temporary phlebitis along the affected vein. Extravasation of vesicant drugs such as anthracyclines, however, may cause severe reactions including progressive tissue damage that may continue to progress over days and weeks. Frequently observed symptoms are pain, redness, swelling, tissue ...
... occurs as a temporary phlebitis along the affected vein. Extravasation of vesicant drugs such as anthracyclines, however, may cause severe reactions including progressive tissue damage that may continue to progress over days and weeks. Frequently observed symptoms are pain, redness, swelling, tissue ...
Fulltext - Brunel University Research Archive
... This technical report pooled data from three studies that measured TPD thresholds bilaterally over the lumbar spine of healthy volunteers. Analyses of these data suggest that there is minimal difference between sides when tactile acuity is assessed horizontally or vertically. Clinicians may wish to ...
... This technical report pooled data from three studies that measured TPD thresholds bilaterally over the lumbar spine of healthy volunteers. Analyses of these data suggest that there is minimal difference between sides when tactile acuity is assessed horizontally or vertically. Clinicians may wish to ...
motor systems
... the descending brainstem pathways, which- originate in many parts of the reticular formation, the vestibular nuclei and some midbrain areas. All movements are influenced by these pathways, which are also of special importance for the regulation of muscle tone and the maintenance of erect posture. Tw ...
... the descending brainstem pathways, which- originate in many parts of the reticular formation, the vestibular nuclei and some midbrain areas. All movements are influenced by these pathways, which are also of special importance for the regulation of muscle tone and the maintenance of erect posture. Tw ...
Failure to mobilize cognitive control for
... et al., 2004; McDowell et al., 2008). This body of work establishes the dACC, DLPFC and VLPFC as key anatomical components of the cognitive control network for volitional saccades. In a prior magnetoencephalography (MEG) study, we found that compared with healthy individuals, schizophrenia patients ...
... et al., 2004; McDowell et al., 2008). This body of work establishes the dACC, DLPFC and VLPFC as key anatomical components of the cognitive control network for volitional saccades. In a prior magnetoencephalography (MEG) study, we found that compared with healthy individuals, schizophrenia patients ...
Clinical neurochemistry
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.