Roles for miRNAs in Timing Developmental Progression Within
... developmental time for defined classes of neurons in vivo, temporally restricted patterns of expression have been documented for many miRNAs (Kosik and Krichevsky, 2005). Additionally, some miRNAs are enriched in dendrites (Kye et al., 2007); given that axons and dendrites of an individual neuron de ...
... developmental time for defined classes of neurons in vivo, temporally restricted patterns of expression have been documented for many miRNAs (Kosik and Krichevsky, 2005). Additionally, some miRNAs are enriched in dendrites (Kye et al., 2007); given that axons and dendrites of an individual neuron de ...
Topographic Organization of Sensory Projection to the Olfactory Bulb
... within a species. These data support a model in which exposure to a given odorant may result in the stimulation of a spatially restricted set of glomeruli, such that the individual odorants would be associated with specific topographic patterns of activity within the olfactory bulb. Introduction in ...
... within a species. These data support a model in which exposure to a given odorant may result in the stimulation of a spatially restricted set of glomeruli, such that the individual odorants would be associated with specific topographic patterns of activity within the olfactory bulb. Introduction in ...
Afferents to the Optic Tectum of the Leopard Frog: An HRP Study
... Scalia and Colman, '75 . Apparently forebrain visual areas do not influence the tectum directly, although a pretectal or tegmental relay may exist. Neary ('76) recently demonstrated ipsilateral retinotectals in several families of anurans. Our study did not reveal this pathway. However, in ranid fro ...
... Scalia and Colman, '75 . Apparently forebrain visual areas do not influence the tectum directly, although a pretectal or tegmental relay may exist. Neary ('76) recently demonstrated ipsilateral retinotectals in several families of anurans. Our study did not reveal this pathway. However, in ranid fro ...
Career of Dennis Dougherty: Ion Channels
... ! Complex: regulated by active pumps, cotransporters, Ca2+, phosphorylation, lipids ! Widespread: all membranes have a potential and use ion channels; also organelles (mitochondria, ER) ...
... ! Complex: regulated by active pumps, cotransporters, Ca2+, phosphorylation, lipids ! Widespread: all membranes have a potential and use ion channels; also organelles (mitochondria, ER) ...
Aggregate Input-Output Models of Neuronal Populations
... order statistics such as cross-correlation and coherence measures are often used to gauge the relationship between the spiking activity of pairs of neurons [4], [5]. However, these are limited measures that provide snapshots of interactions between individual neurons from different regions. They she ...
... order statistics such as cross-correlation and coherence measures are often used to gauge the relationship between the spiking activity of pairs of neurons [4], [5]. However, these are limited measures that provide snapshots of interactions between individual neurons from different regions. They she ...
Brainstem (II)
... ‐‐ silent during sleep, active during wakefulness ‐‐ form part of the ascending reticular activating system ‐ Reticular formation in the lateral part of medulla ‐‐ send fibers to spinal cord ‐ Solitary nucleus and dorsal motor nucleus of vagus ...
... ‐‐ silent during sleep, active during wakefulness ‐‐ form part of the ascending reticular activating system ‐ Reticular formation in the lateral part of medulla ‐‐ send fibers to spinal cord ‐ Solitary nucleus and dorsal motor nucleus of vagus ...
- Warwick WRAP
... Recently, an abundance of research has been carried out into the use of polypeptide-based vehicles as drug delivery systems. Assemblies such as micelles, vesicles, hydrogels, nanogels, capsules, fibres, dendritic and macromolecular drug conjugates, nucleic acid complexes and polyplexes have all bee ...
... Recently, an abundance of research has been carried out into the use of polypeptide-based vehicles as drug delivery systems. Assemblies such as micelles, vesicles, hydrogels, nanogels, capsules, fibres, dendritic and macromolecular drug conjugates, nucleic acid complexes and polyplexes have all bee ...
REVIEWS - Ping Pong
... minutes. However, the magnitude of each of these rapid fluctuations of insulin is directly proportional to the size of the adipose mass. So, insulin provides the brain with information about ongoing glucose availability and use, as well as about body fat. Another difference is that leptin is a bette ...
... minutes. However, the magnitude of each of these rapid fluctuations of insulin is directly proportional to the size of the adipose mass. So, insulin provides the brain with information about ongoing glucose availability and use, as well as about body fat. Another difference is that leptin is a bette ...
Patients with Ehlers Danlos syndrome and CRPS
... Received I September 2005; received in revised form 6 February 2006; accepted 7 February 2006 ...
... Received I September 2005; received in revised form 6 February 2006; accepted 7 February 2006 ...
identification of a cell surface glycoprotein family of olfactory
... and Warren, 1982), as well as the reciprocal distribution (Vulliamy et al., 1981), to retinal photoreceptor cells (Barnstable, 1980), and to cat CNS neuronal subclasses (McKay and Hockfield, 1982). We have developed an Mab, 2B8, which binds to cell surface antigens on primary sensory neurons of the ...
... and Warren, 1982), as well as the reciprocal distribution (Vulliamy et al., 1981), to retinal photoreceptor cells (Barnstable, 1980), and to cat CNS neuronal subclasses (McKay and Hockfield, 1982). We have developed an Mab, 2B8, which binds to cell surface antigens on primary sensory neurons of the ...
Pallidal Origin of GABA Release within the Substantia Nigra Pars
... in isopentane at ⫺30°C. All animals bearing 6-OHDA lesions (n ⫽ 30) were perfused transcardially under chloral hydrate anesthesia with 100 ml of 0.9% NaCl, pH 7.2, supplemented with heparin (5 ⫻ 10 4 IU/ml), followed by 350 ml of cold fixative consisting of 4% paraformaldehyde in 0.1 M PBS, pH 7.3 ( ...
... in isopentane at ⫺30°C. All animals bearing 6-OHDA lesions (n ⫽ 30) were perfused transcardially under chloral hydrate anesthesia with 100 ml of 0.9% NaCl, pH 7.2, supplemented with heparin (5 ⫻ 10 4 IU/ml), followed by 350 ml of cold fixative consisting of 4% paraformaldehyde in 0.1 M PBS, pH 7.3 ( ...
Hydrodynamic Studies on the Manganese
... mg/mL yielded a calculated molecular mass for the manganese-stabilizing protein of 26.65 and 26.52 kDa, respectively, using V ) 0.7317 mL/g. These values are in excellent agreement with the actual molecular mass of 26.531 kDa as determined by analysis of the derived amino acid sequence and as experi ...
... mg/mL yielded a calculated molecular mass for the manganese-stabilizing protein of 26.65 and 26.52 kDa, respectively, using V ) 0.7317 mL/g. These values are in excellent agreement with the actual molecular mass of 26.531 kDa as determined by analysis of the derived amino acid sequence and as experi ...
Neural ensemble coding and statistical periodicity: Speculations on
... Certainly changes in the inter-spike interval histograms of neurons can be readily demonstrated [64], for example, in cortical neurons between sleep and wake [21], and in retinal ganglion cells as the ambient light level changes [76]. However, the clearest evidence for spatio-temporal distribution c ...
... Certainly changes in the inter-spike interval histograms of neurons can be readily demonstrated [64], for example, in cortical neurons between sleep and wake [21], and in retinal ganglion cells as the ambient light level changes [76]. However, the clearest evidence for spatio-temporal distribution c ...
Stress - Neuroanatomy
... 1. Which of the following is FALSE regarding lesions of the amygdala? A. TRUE a lesion would affect emotional memories! JKH note of interest: Imagine driving down the road and having an accident. You hit your head on the steering wheel and the horn gets stuck on. You're bleeding and in pain. It's aw ...
... 1. Which of the following is FALSE regarding lesions of the amygdala? A. TRUE a lesion would affect emotional memories! JKH note of interest: Imagine driving down the road and having an accident. You hit your head on the steering wheel and the horn gets stuck on. You're bleeding and in pain. It's aw ...
PDF
... of the growth cones directly to its target area and the elimination of the others (Kuwada, 1982; Kuwada & Kramer, 1983). Consistent with this hypothesis are the two main findings of this investigation. 1) The primary growth cone of the PD neuron is the first growth cone to traverse the DP pathway an ...
... of the growth cones directly to its target area and the elimination of the others (Kuwada, 1982; Kuwada & Kramer, 1983). Consistent with this hypothesis are the two main findings of this investigation. 1) The primary growth cone of the PD neuron is the first growth cone to traverse the DP pathway an ...
The Physiology of the Afferent and Efferent Arterioles
... • The kidney receives sympathetic innervation that extends to the vascular smooth muscle cells, juxtaglomerular renin-secreting cells, and mesangium as well as the proximal and distal tubules and the loop of Henle. • The afferent arterioles are threefold more densely innervated than the efferent art ...
... • The kidney receives sympathetic innervation that extends to the vascular smooth muscle cells, juxtaglomerular renin-secreting cells, and mesangium as well as the proximal and distal tubules and the loop of Henle. • The afferent arterioles are threefold more densely innervated than the efferent art ...
Volitional enhancement of firing synchrony and oscillation
... accompanied by a correlated increase in the synchrony of the entrained neurons. This relation of LFP and neuronal firing can be explained by the fact that LFPs are produced by postsynaptic potentials, and periodicity in neuronal firing would be associated with periodicity in LFPs. They also document ...
... accompanied by a correlated increase in the synchrony of the entrained neurons. This relation of LFP and neuronal firing can be explained by the fact that LFPs are produced by postsynaptic potentials, and periodicity in neuronal firing would be associated with periodicity in LFPs. They also document ...
A local circuit approach to understanding integration of
... and suppression effects tend to be strongest for iso-orientation surrounds. (a) Typical data from a cell in cat V1 obtained by Toth et al. (1996) but presented here for the first time. Increasing the contrast of an optimally oriented grating stimulus (presented to the classical receptive field in co ...
... and suppression effects tend to be strongest for iso-orientation surrounds. (a) Typical data from a cell in cat V1 obtained by Toth et al. (1996) but presented here for the first time. Increasing the contrast of an optimally oriented grating stimulus (presented to the classical receptive field in co ...
Molecular modeling of HIV-1 reverse
... resistance, although the specific mutants that are responsible differ for the most part between the two classes of drugs (Boyer et al., 1994a,b). In order to combat this problem, combination therapy, which combines inhibitors from both classes, is now being used as a means to enhance virus suppressi ...
... resistance, although the specific mutants that are responsible differ for the most part between the two classes of drugs (Boyer et al., 1994a,b). In order to combat this problem, combination therapy, which combines inhibitors from both classes, is now being used as a means to enhance virus suppressi ...
Serotonin - Meridian Kinesiology
... Tissues) are antagonized by Antigens that are responsible for Allergies and Inflammation, they "burst" and release Serotonin (amongst other substances) as part of their defence response. Serotonin released in response to Inflammation is involved in the sensation Pain associated with Inflammation. Ne ...
... Tissues) are antagonized by Antigens that are responsible for Allergies and Inflammation, they "burst" and release Serotonin (amongst other substances) as part of their defence response. Serotonin released in response to Inflammation is involved in the sensation Pain associated with Inflammation. Ne ...
Full Text
... similar in all case but varied based on disease duration (Table 1). In all cases frontal white matter was devastated. In case 3 a brain biopsy preformed early in the disease course, 10 months prior to death, demonstrated ill-defined areas of white matter destruction with numerous axonal spheroid and ...
... similar in all case but varied based on disease duration (Table 1). In all cases frontal white matter was devastated. In case 3 a brain biopsy preformed early in the disease course, 10 months prior to death, demonstrated ill-defined areas of white matter destruction with numerous axonal spheroid and ...
Document
... mechanisms of acupuncture involve the spinal cord grey matter, hypothalamic-pituitary axis, midbrain periaqueductal grey matter, medulla oblongata, limbic system, cerebral cortex, and autonomic nervous system. Electroacupuncture (EA) stimulation of these sites results in activation of descending pat ...
... mechanisms of acupuncture involve the spinal cord grey matter, hypothalamic-pituitary axis, midbrain periaqueductal grey matter, medulla oblongata, limbic system, cerebral cortex, and autonomic nervous system. Electroacupuncture (EA) stimulation of these sites results in activation of descending pat ...
Slide 1
... plasma membrane supports the prediction that PERK1 is an integral membrane protein protein…these kinases have been implicated in early stages of wound ...
... plasma membrane supports the prediction that PERK1 is an integral membrane protein protein…these kinases have been implicated in early stages of wound ...
The Olfactory Sensory Map in Drosophila
... domain proteins42‑44 to identify candidate Drosophila ORs. There are a total of 62 ORs, encoded by a family of 60 genes through alternative splicing.45 The fly OR genes encode a highly divergent family of membrane‑associated proteins that are selectively expressed in Drosophila OSNs.42‑44 These prot ...
... domain proteins42‑44 to identify candidate Drosophila ORs. There are a total of 62 ORs, encoded by a family of 60 genes through alternative splicing.45 The fly OR genes encode a highly divergent family of membrane‑associated proteins that are selectively expressed in Drosophila OSNs.42‑44 These prot ...
Clinical neurochemistry
Clinical neurochemistry is the field of neurological biochemistry which relates biochemical phenomena to clinical symptomatic manifestations in humans. While neurochemistry is mostly associated with the effects of neurotransmitters and similarly-functioning chemicals on neurons themselves, clinical neurochemistry relates these phenomena to system-wide symptoms. Clinical neurochemistry is related to neurogenesis, neuromodulation, neuroplasticity, neuroendocrinology, and neuroimmunology in the context of associating neurological findings at both lower and higher level organismal functions.