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What is real? How do you define real?
What is real? How do you define real?

... what are they !responding to"? Action potentials convey information through their timing. Although ac• sensory neuroscience: activity as a function of sensory stimulus (eg. tion potentials can vary somewhat in duration, amplitude, and shape, image, skin stimulation, sound, odor etc..). they visual a ...
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... – changes in charge can affect membrane proteins such as channels, – other membrane channels allow for ions to flow down concentration gradients, creating a change that can affect other membrane potentials. – Excitable tissues have Na+ & K+ channels that operate at a threshold level ...
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... the cell can be excited again. • Wave wider or narrower- do to the propagation of the action potential. When all parts of the membrane excite at the same time it creates a stronger pulse. Like when you throw a pebble to the ocean as compared to a big stone. • Graph are not identical, and different p ...
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... A neuron is resting when its membrane forms a partial barrier between the inside and outside of the neuron. The solution contains electrically charged particles called ions. When the neuron is at rest, there are more negative ions on the outside which is called the resting potential. A resting neuro ...
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... there are other ways of storing information. However, these other ways were not discussed. What other ways of storing information are there in the brain? A: 1. geometry of neurons 2. short term information may be stored in the temporal differences in the oscillation of neurons, 3. 4. How do synapses ...
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ppt - UK College of Arts & Sciences

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... to a change in membrane potential. • When a stimulus depolarizes the membrane, Na+ channels open, allowing Na+ to diffuse into the cell. • The movement of Na+ into the cell increases the depolarization and causes even more Na+ channels to open. • A strong stimulus results in a massive change in memb ...
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...  Active transport mechanism in plasma membrane that transports sodium (Na+) and potassium (K+) ions in opposite directions and at different rates  Maintains an imbalance in the distribution of positive ions, resulting in the inside surface becoming slightly negative compared with its outer surface ...
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... B) regenerating cell bodies for the neurons. C) forming a cellular tube that directs axonal regeneration. D) clearing away cellular debris. E) producing more satellite cells that fuse to form new axons. 16) Opening of sodium channels in the axon membrane causes A) depolarization. B) repolarization. ...
Ion Channel Structure and Function (part 1)
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... Function: as a generalization, Kir help maintain the resting membrane potential and control excitability of neurons and muscle cells; transepithelial K+ transport (Kir1.1, Kir7.1), G protein coupled (serotonin, metabotropic glutamate, etc.) receptor-dependent membrane hyperpolarization, regulation o ...
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Action potential



In physiology, an action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and endocrine cells, as well as in some plant cells. In neurons, they play a central role in cell-to-cell communication. In other types of cells, their main function is to activate intracellular processes. In muscle cells, for example, an action potential is the first step in the chain of events leading to contraction. In beta cells of the pancreas, they provoke release of insulin. Action potentials in neurons are also known as ""nerve impulses"" or ""spikes"", and the temporal sequence of action potentials generated by a neuron is called its ""spike train"". A neuron that emits an action potential is often said to ""fire"".Action potentials are generated by special types of voltage-gated ion channels embedded in a cell's plasma membrane. These channels are shut when the membrane potential is near the resting potential of the cell, but they rapidly begin to open if the membrane potential increases to a precisely defined threshold value. When the channels open (in response to depolarization in transmembrane voltage), they allow an inward flow of sodium ions, which changes the electrochemical gradient, which in turn produces a further rise in the membrane potential. This then causes more channels to open, producing a greater electric current across the cell membrane, and so on. The process proceeds explosively until all of the available ion channels are open, resulting in a large upswing in the membrane potential. The rapid influx of sodium ions causes the polarity of the plasma membrane to reverse, and the ion channels then rapidly inactivate. As the sodium channels close, sodium ions can no longer enter the neuron, and then they are actively transported back out of the plasma membrane. Potassium channels are then activated, and there is an outward current of potassium ions, returning the electrochemical gradient to the resting state. After an action potential has occurred, there is a transient negative shift, called the afterhyperpolarization or refractory period, due to additional potassium currents. This mechanism prevents an action potential from traveling back the way it just came.In animal cells, there are two primary types of action potentials. One type is generated by voltage-gated sodium channels, the other by voltage-gated calcium channels. Sodium-based action potentials usually last for under one millisecond, whereas calcium-based action potentials may last for 100 milliseconds or longer. In some types of neurons, slow calcium spikes provide the driving force for a long burst of rapidly emitted sodium spikes. In cardiac muscle cells, on the other hand, an initial fast sodium spike provides a ""primer"" to provoke the rapid onset of a calcium spike, which then produces muscle contraction.
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