12146005
... extended period of time. This characteristic of the dosage form further decreases frequency of drug intake ensuring better patient compliance and often reduces adverse effects associated with drug. The aim of the present study was to design and develop an optimized once daily oral sustained release ...
... extended period of time. This characteristic of the dosage form further decreases frequency of drug intake ensuring better patient compliance and often reduces adverse effects associated with drug. The aim of the present study was to design and develop an optimized once daily oral sustained release ...
EFFECT OF TWO DIFFERENT DILUENTS ON RELEASE PROFILE OF ACECLOFENAC FROM SUSTAINED RELEASE MATRIX TABLETS USING GUM DAMAR AS RELEASE RETARDANT
... In the present work the effect of two different diluents namely dicalcium phosphate (DCP) and maize starch (MS) on the release of aceclofenac from sustained release matrix tablets has been studied. Gum damar (GD), a hydrophobic polymer with significant binding property was used as a release retard ...
... In the present work the effect of two different diluents namely dicalcium phosphate (DCP) and maize starch (MS) on the release of aceclofenac from sustained release matrix tablets has been studied. Gum damar (GD), a hydrophobic polymer with significant binding property was used as a release retard ...
Basic concepts of Pharmacology. Pharmacokinetics of drugs.
... 6. The characteristic of direct and indirect, reversible and irreversible, main and adverse (side) action. 7. Dependence of action of drugs on external factors. A doze (definition, classification). a therapeutic index. 8. Dependence of action of drugs on physical and chemical properties (solubility, ...
... 6. The characteristic of direct and indirect, reversible and irreversible, main and adverse (side) action. 7. Dependence of action of drugs on external factors. A doze (definition, classification). a therapeutic index. 8. Dependence of action of drugs on physical and chemical properties (solubility, ...
RATIONALIZATION OF TWO DOSAGE FORMS OF A MODEL COMPOUND ALPRAZOLAM,
... characteristics phenotypic criteria like metabolism and therapeutic effects are influenced by environmental factors such as age, disease, drug interactions due to co-administration etc [3,4,11]. Based on these pharmaco-metabonomic phenotyping has been used in the individualization of drug dosages [5 ...
... characteristics phenotypic criteria like metabolism and therapeutic effects are influenced by environmental factors such as age, disease, drug interactions due to co-administration etc [3,4,11]. Based on these pharmaco-metabonomic phenotyping has been used in the individualization of drug dosages [5 ...
Urine Drug Screening: Practical Guide for Clinicians
... Practical Guide for Clinicians KAREN E. MOELLER, PHARMD, BCPP; KELLY C. LEE, PHARMD, BCPP; AND JULIE C. KISSACK, PHARMD, BCPP Drug testing, commonly used in health care, workplace, and criminal settings, has become widespread during the past decade. Urine drug screens have been the most common metho ...
... Practical Guide for Clinicians KAREN E. MOELLER, PHARMD, BCPP; KELLY C. LEE, PHARMD, BCPP; AND JULIE C. KISSACK, PHARMD, BCPP Drug testing, commonly used in health care, workplace, and criminal settings, has become widespread during the past decade. Urine drug screens have been the most common metho ...
Urine Drug Screening: Practical Guide for Clinicians
... Practical Guide for Clinicians KAREN E. MOELLER, PHARMD, BCPP; KELLY C. LEE, PHARMD, BCPP; AND JULIE C. KISSACK, PHARMD, BCPP Drug testing, commonly used in health care, workplace, and criminal settings, has become widespread during the past decade. Urine drug screens have been the most common metho ...
... Practical Guide for Clinicians KAREN E. MOELLER, PHARMD, BCPP; KELLY C. LEE, PHARMD, BCPP; AND JULIE C. KISSACK, PHARMD, BCPP Drug testing, commonly used in health care, workplace, and criminal settings, has become widespread during the past decade. Urine drug screens have been the most common metho ...
WHO Drug Information - World Health Organization
... to the normal INN system, the naming of individual components of each series requires specific decisions on the extent of supplementary information to be included in the name. Those issues may vary for individual groups, but the following remarks apply to all situations. General rules for the constr ...
... to the normal INN system, the naming of individual components of each series requires specific decisions on the extent of supplementary information to be included in the name. Those issues may vary for individual groups, but the following remarks apply to all situations. General rules for the constr ...
DEVELOPMENT AND VALIDATION OF A RP-HPLC METHOD FOR THE DETECTION... MEROPENEM AS A PURE COMPOUND, IN A PHARMACEUTICAL DOSAGE FORM...
... minutes. Observations were made for interfering peaks generated by degradation products during the analyses. RESULTS The most suitable isocratic condition to resolve Meropenem with a C-18 column after the chromatographic conditions were optimised for specificity, resolution and retention timewas a m ...
... minutes. Observations were made for interfering peaks generated by degradation products during the analyses. RESULTS The most suitable isocratic condition to resolve Meropenem with a C-18 column after the chromatographic conditions were optimised for specificity, resolution and retention timewas a m ...
Medications in the Breast-Feeding Mother
... is considered safe for use during breast-feeding.10 Based on studies of the distribution of first-generation sulfonylureas into breast milk, the AAP considers tolbutamide (Orinase) to be compatible with breast-feeding.6,11 Information on other diabetic agents is less complete. Glyburide (Micronase) ...
... is considered safe for use during breast-feeding.10 Based on studies of the distribution of first-generation sulfonylureas into breast milk, the AAP considers tolbutamide (Orinase) to be compatible with breast-feeding.6,11 Information on other diabetic agents is less complete. Glyburide (Micronase) ...
Nanotechnology in Drug Discovery-Development and
... • The additional information about effectiveness and safety that is needed to evaluate the overall benefit-risk relationship of the drug. • Phase 3 studies usually include several hundred to several thousand people. ...
... • The additional information about effectiveness and safety that is needed to evaluate the overall benefit-risk relationship of the drug. • Phase 3 studies usually include several hundred to several thousand people. ...
Children Tylenol with Flavor Creator
... TORONTO - The majority of Canadians are unaware of the health risks posed by certain common pain relievers, according to a national survey released today. More than threequarters (76 per cent) are unaware that certain common pain relievers can cause serious gastrointestinal side effects, particularl ...
... TORONTO - The majority of Canadians are unaware of the health risks posed by certain common pain relievers, according to a national survey released today. More than threequarters (76 per cent) are unaware that certain common pain relievers can cause serious gastrointestinal side effects, particularl ...
SOLID LIPID NANOPARTICLES: A REVIEW
... Solid lipid nanoparticles (SLN) introduced in 1991 represent an alternative carrier system to tradition colloidal carriers such as - emulsions, liposomes and polymeric micro – and nanoparticles1. Nanoparticles made from solid lipids are attracting major attention as novel colloidal drug carrier for ...
... Solid lipid nanoparticles (SLN) introduced in 1991 represent an alternative carrier system to tradition colloidal carriers such as - emulsions, liposomes and polymeric micro – and nanoparticles1. Nanoparticles made from solid lipids are attracting major attention as novel colloidal drug carrier for ...
Misc topic, Medicine and Drugs
... and interfere with the signal flowing through the nervous system. ...
... and interfere with the signal flowing through the nervous system. ...
pharmaceutical calculations in prescription compounding
... Before proceeding with any calculation, pharmacists should do the following: (a) read the entire formula or prescription carefully; (b) determine which materials are needed; and then (c) select the appropriate methods of preparation and the appropriate calculation. There are often several ways to so ...
... Before proceeding with any calculation, pharmacists should do the following: (a) read the entire formula or prescription carefully; (b) determine which materials are needed; and then (c) select the appropriate methods of preparation and the appropriate calculation. There are often several ways to so ...
Simulated Biological Fluids with Possible Application in Dissolution
... generally much lower than that of parenteral therapy (1). Nevertheless, the oral route is not without disadvantages, particularly with respect to labile drugs such as peptide- and oligonucleotide-based pharmaceuticals. During the last decades, numerous novel oral drug delivery systems such as mucoad ...
... generally much lower than that of parenteral therapy (1). Nevertheless, the oral route is not without disadvantages, particularly with respect to labile drugs such as peptide- and oligonucleotide-based pharmaceuticals. During the last decades, numerous novel oral drug delivery systems such as mucoad ...
Reassessing Bioavailability of Silymarin
... hepatoprotection by silymarin liposomes compared to 33- and 24 percent by non-liposomal silymarin and liposomes without silymarin, respectively.30 Liposomes, even without silymarin, can convey some hepatoprotective effects because of their liver supportive phospholipid content. Xiao et al studied ph ...
... hepatoprotection by silymarin liposomes compared to 33- and 24 percent by non-liposomal silymarin and liposomes without silymarin, respectively.30 Liposomes, even without silymarin, can convey some hepatoprotective effects because of their liver supportive phospholipid content. Xiao et al studied ph ...
Urine Drug Testing Practices - Canadian Nuclear Safety Commission
... The screening and confirmation cut-off values used in different programmes are not always identical and these cut-off values are modified over time as new information about drug metabolism and excretion is published and technological advances are available in the laboratory. It is important to appre ...
... The screening and confirmation cut-off values used in different programmes are not always identical and these cut-off values are modified over time as new information about drug metabolism and excretion is published and technological advances are available in the laboratory. It is important to appre ...
BioInvent Financial Statement
... complement to, the n-CoDeR platform, is garnering great interest. F.I.R.S.T™ is our new function-based platform for the simultaneous identification of disease-associated target structures and antibody-based drugs. F.I.R.S.T™ provides a unique method to make an early identification of the target stru ...
... complement to, the n-CoDeR platform, is garnering great interest. F.I.R.S.T™ is our new function-based platform for the simultaneous identification of disease-associated target structures and antibody-based drugs. F.I.R.S.T™ provides a unique method to make an early identification of the target stru ...
Perspective Herb–Drug Interactions: Challenges and Opportunities
... Irreversible Inhibition. Inhibition by perpetrators that do not associate and dissociate rapidly from the enzyme is termed timedependent inhibition (TDI). Mechanism-based inhibition (MBI), often observed as TDI, is characterized by irreversible or quasi-irreversible noncovalent binding of a reactive ...
... Irreversible Inhibition. Inhibition by perpetrators that do not associate and dissociate rapidly from the enzyme is termed timedependent inhibition (TDI). Mechanism-based inhibition (MBI), often observed as TDI, is characterized by irreversible or quasi-irreversible noncovalent binding of a reactive ...
Sonophoresis - International Journal of Pharmacy and Technology
... kHz–16 MHz with intensities of up to 3W/cm2 has been used for sonophoresis8, 11. Ultrasound parameters such as treatment duration, intensity, and frequency are all known to affect percutaneous absorption, with the later being the most important12. Sonophoresis occurs because ultrasound waves stimula ...
... kHz–16 MHz with intensities of up to 3W/cm2 has been used for sonophoresis8, 11. Ultrasound parameters such as treatment duration, intensity, and frequency are all known to affect percutaneous absorption, with the later being the most important12. Sonophoresis occurs because ultrasound waves stimula ...
REVIEW Chiral Toxicology: It`s the Same Thing...Only Different
... toxicities. R()-salbutamol (albuterol) is responsible for bronchodilator effects. S(þ)-salbutamol has little bronchodilating activity, actually causes hyperkalemia, and has been implicated in eosinophil activation and pro-inflammatory properties (Vakily et al., 2002). Unfortunately, R()-salbutamol ...
... toxicities. R()-salbutamol (albuterol) is responsible for bronchodilator effects. S(þ)-salbutamol has little bronchodilating activity, actually causes hyperkalemia, and has been implicated in eosinophil activation and pro-inflammatory properties (Vakily et al., 2002). Unfortunately, R()-salbutamol ...
SENATE BILL 15-053 BY SENATOR(S) Aguilar, Crowder, Guzman
... PRACTICE NURSE WHO HAS PRESCRIPTIVE AUTHORITY PURSUANT TO SECTION 12-38-111.6, C.R.S., physician assistant, or pharmacist; or (e) "Opiate-related drug overdose event" means an acute condition, including but not limited to a decreased level of consciousness or respiratory depression, resulting THAT: ...
... PRACTICE NURSE WHO HAS PRESCRIPTIVE AUTHORITY PURSUANT TO SECTION 12-38-111.6, C.R.S., physician assistant, or pharmacist; or (e) "Opiate-related drug overdose event" means an acute condition, including but not limited to a decreased level of consciousness or respiratory depression, resulting THAT: ...
(Zofran) Training Module - Nor
... Zofran may have value in the treatment of schizophrenia, as an adjunct to haloperidol. Parkinson’s: Studies have indicated that Zofran may be a possible treatment for psychosis resulting from advanced Parkinson’s disease. Alcoholism: Zofran has been found to lower the cravings for alcohol, espec ...
... Zofran may have value in the treatment of schizophrenia, as an adjunct to haloperidol. Parkinson’s: Studies have indicated that Zofran may be a possible treatment for psychosis resulting from advanced Parkinson’s disease. Alcoholism: Zofran has been found to lower the cravings for alcohol, espec ...