Hox Genes - Wyoming Scholars Repository
... the quantities of Hox gene protein products are off - either too much or too little is created.15 While Hox genes have been implicated in dozens of different types of cancer, only colon, breast, and prostate cancer will be directly addressed for clarity and simplicity. In colon cancer the HOXA famil ...
... the quantities of Hox gene protein products are off - either too much or too little is created.15 While Hox genes have been implicated in dozens of different types of cancer, only colon, breast, and prostate cancer will be directly addressed for clarity and simplicity. In colon cancer the HOXA famil ...
Tracking the evolution of 3D gene organization demonstrates its
... Previous results have implied that 3D organization, function and expression co-evolve (4). However, almost all studies to date have analyzed one organism. Recent studies that analyzed more than one organism have analyzed each of them independently from others (3,4,19–21). For example, some degree of ...
... Previous results have implied that 3D organization, function and expression co-evolve (4). However, almost all studies to date have analyzed one organism. Recent studies that analyzed more than one organism have analyzed each of them independently from others (3,4,19–21). For example, some degree of ...
AzotoOxidativePhosphorylation
... Azotobacter vinelandii exhibits redundancy for two ATP synthase F1 sector subunits, alpha and beta. Avin19740 shows strong similarity (e-105) to the alpha subunit Avin52180. Avin19670 shows strong similarity (e-114 ) to the beta subunit Avin52160. Redundancy is seen for some F0 subunits, but with ...
... Azotobacter vinelandii exhibits redundancy for two ATP synthase F1 sector subunits, alpha and beta. Avin19740 shows strong similarity (e-105) to the alpha subunit Avin52180. Avin19670 shows strong similarity (e-114 ) to the beta subunit Avin52160. Redundancy is seen for some F0 subunits, but with ...
The Role of Mutation Rate Variation and Genetic Diversity in the
... Replication time data were from Chen et al. [18] and Hansen et al. [19]. Qualitatively similar results were obtained using each of four replication time datasets, so we only present the analysis using data from an embryonic stem cell line BG02 [19]. Germ-line expression data were from a study by McV ...
... Replication time data were from Chen et al. [18] and Hansen et al. [19]. Qualitatively similar results were obtained using each of four replication time datasets, so we only present the analysis using data from an embryonic stem cell line BG02 [19]. Germ-line expression data were from a study by McV ...
Managing Polygenic Disease: Canine Hip Dysplasia as an Example
... on a high liability for dysplasia through their contributing high numbers of the additive genes. A trigger gene in one breed or family may be different from the gene in others. Consequently, if a test for a trigger gene is developed in one breed or family, it may not provide useful information for a ...
... on a high liability for dysplasia through their contributing high numbers of the additive genes. A trigger gene in one breed or family may be different from the gene in others. Consequently, if a test for a trigger gene is developed in one breed or family, it may not provide useful information for a ...
Genome-scale profiling of histone H3.3 replacement patterns
... RNA polymerase II (Pol II; using an antibody to the C-terminal domain) had patterns that corresponded closely with those of H3.3 (Fig. 2e,f). We also observed this similarity between H3.3 and markers of active chromatin and transcription for other gene-rich regions. Therefore, replication-independen ...
... RNA polymerase II (Pol II; using an antibody to the C-terminal domain) had patterns that corresponded closely with those of H3.3 (Fig. 2e,f). We also observed this similarity between H3.3 and markers of active chromatin and transcription for other gene-rich regions. Therefore, replication-independen ...
Biomarkers for Epithelial Ovarian Cancers
... the genes are ranked according to the MPEs. The lower the MPE, the better is the gene. This method of gene selection technique uses the ideas from Bayesian decision theory and probability density estimation techniques. Unlike most other methods (e.g., correlation-based methods), this method performs ...
... the genes are ranked according to the MPEs. The lower the MPE, the better is the gene. This method of gene selection technique uses the ideas from Bayesian decision theory and probability density estimation techniques. Unlike most other methods (e.g., correlation-based methods), this method performs ...
Comprehension Questions
... Conversely, a negative interference value, where more double crossovers occur than expected, suggests that a crossover event can stimulate additional crossover events in the same region of the chromosome. 11. List some of the methods for physically mapping genes and explain how they are used to posi ...
... Conversely, a negative interference value, where more double crossovers occur than expected, suggests that a crossover event can stimulate additional crossover events in the same region of the chromosome. 11. List some of the methods for physically mapping genes and explain how they are used to posi ...
Chapter 14
... A phage infective cycle is divided into the early period (before replication) and the late period (after the onset of replication). A phage infection generates a pool of progeny phage genomes that replicate and recombine. ...
... A phage infective cycle is divided into the early period (before replication) and the late period (after the onset of replication). A phage infection generates a pool of progeny phage genomes that replicate and recombine. ...
Individual eukaryotic genomes
... Individual eukaryotic genomes: the mouse Mus musculus M. musculus is the second mammal to have its genome sequenced. Mouse diverged from human 75 MYA. Distinguishing features: only 300 of 30,000 annotated genes have no human orthologs Genome size: 2.5 Gb (euchromatic portion)(cf. 2.9 Gb human) Chro ...
... Individual eukaryotic genomes: the mouse Mus musculus M. musculus is the second mammal to have its genome sequenced. Mouse diverged from human 75 MYA. Distinguishing features: only 300 of 30,000 annotated genes have no human orthologs Genome size: 2.5 Gb (euchromatic portion)(cf. 2.9 Gb human) Chro ...
Studies of codon usage and tRNA genes of 18 unicellular organisms
... We examined codon usage in Bacillus subtilis genes by multivariate analysis, quantified its cellular levels of individual tRNAs, and found a clear constraint of tRNA contents on synonymous codon choice. Individual tRNA levels were proportional to the copy number of the respective tRNA genes. This in ...
... We examined codon usage in Bacillus subtilis genes by multivariate analysis, quantified its cellular levels of individual tRNAs, and found a clear constraint of tRNA contents on synonymous codon choice. Individual tRNA levels were proportional to the copy number of the respective tRNA genes. This in ...
Novel Antibacterials: A Genomics Approach to Drug Discovery
... bacterial species, is introduced into the organism and drugresistant colonies identified. The plasmid DNA is only maintained following homologous recombination into the target gene, and will therefore disrupt it. The method is efficient, but has caveats: in many cases significant portions of the "di ...
... bacterial species, is introduced into the organism and drugresistant colonies identified. The plasmid DNA is only maintained following homologous recombination into the target gene, and will therefore disrupt it. The method is efficient, but has caveats: in many cases significant portions of the "di ...
Genome Analysis of Cyanobacteria
... group of prokaryotes. Although their phylogenetic position in the bacterial kingdom is still uncertain, cyanobacteria are believed to be genetically related to gram-positive bacteria. Cyanobacteria are capable of photosynthesis but are distinct from other photosynthetic bacteria, such as purple and ...
... group of prokaryotes. Although their phylogenetic position in the bacterial kingdom is still uncertain, cyanobacteria are believed to be genetically related to gram-positive bacteria. Cyanobacteria are capable of photosynthesis but are distinct from other photosynthetic bacteria, such as purple and ...
Document
... dictated the function of the models, not gene participation, and because technically and theoretically it turned out to be simpler. However, information from the gene-based approach (e.g. listings of reactions that each gene participated in in the models) was also deemed valuable to the reconciliati ...
... dictated the function of the models, not gene participation, and because technically and theoretically it turned out to be simpler. However, information from the gene-based approach (e.g. listings of reactions that each gene participated in in the models) was also deemed valuable to the reconciliati ...
Analysis of mutant strains
... known, and scientists faced the challenge of associating genes with enzymatic activities. You can see from the pathway that mutations in 11 different MET genes would produce a phenotype in which strains would grow in the presence of methionine, but not in its absence. The scientists narrowed down po ...
... known, and scientists faced the challenge of associating genes with enzymatic activities. You can see from the pathway that mutations in 11 different MET genes would produce a phenotype in which strains would grow in the presence of methionine, but not in its absence. The scientists narrowed down po ...
HSLS3-3 - North Bergen School District
... end up in the same egg with the chromosome that has the W allele or with the chromosome that has the w allele. (This is illustrated in the figure on page 2.) In this activity, when you dropped the two chromosome Popsicle sticks, each stick independently landed with one particular side up, and this c ...
... end up in the same egg with the chromosome that has the W allele or with the chromosome that has the w allele. (This is illustrated in the figure on page 2.) In this activity, when you dropped the two chromosome Popsicle sticks, each stick independently landed with one particular side up, and this c ...
Quantitative Inheritance
... number, etc. A spectrum of phenotypic classes occur which contain continuous variations . Each quantitative trait is governed by many non-allelic genes or polygenes. Environmental conditions effect the phenotypic expression of polygenes variously. It concerns with a population of organisms consistin ...
... number, etc. A spectrum of phenotypic classes occur which contain continuous variations . Each quantitative trait is governed by many non-allelic genes or polygenes. Environmental conditions effect the phenotypic expression of polygenes variously. It concerns with a population of organisms consistin ...
Gene Loss and Evolutionary Rates Following Whole
... Out of 2,371 human genes with a clear orthology relation to mapped Tetraodon genes, 364 have a phylogenetic profile typical of the WGD in Tetraodon (see Materials and Methods). This gives an estimate of 15% of gene pairs retained after the WGD, that is, loss of one of the paralogs in 85% of pairs. T ...
... Out of 2,371 human genes with a clear orthology relation to mapped Tetraodon genes, 364 have a phylogenetic profile typical of the WGD in Tetraodon (see Materials and Methods). This gives an estimate of 15% of gene pairs retained after the WGD, that is, loss of one of the paralogs in 85% of pairs. T ...
F. nucleatum - California State University, Long Beach
... The incorporation of Neu5Ac into F. nucleatum LPS can hinder the function of the host defenses via disruption of the complement pathway as has been shown in the case of N. gonorrhoeae, which is resistant to complement activation due to the presence of Neu5Ac in the bacterium LPS. Siaylation of F ...
... The incorporation of Neu5Ac into F. nucleatum LPS can hinder the function of the host defenses via disruption of the complement pathway as has been shown in the case of N. gonorrhoeae, which is resistant to complement activation due to the presence of Neu5Ac in the bacterium LPS. Siaylation of F ...
Dragon Genetics - Chester Upland School District
... 4. To illustrate how the Law of Independent Assortment applies to humans, consider the inheritance of the recessive allele for sickle cell anemia (s, located on chromosome 11) and the SRY gene (the gene that results in male development, which is located on the Y chromosome). Suppose that a father an ...
... 4. To illustrate how the Law of Independent Assortment applies to humans, consider the inheritance of the recessive allele for sickle cell anemia (s, located on chromosome 11) and the SRY gene (the gene that results in male development, which is located on the Y chromosome). Suppose that a father an ...
Extraction of correlated gene clusters from multiple genomic data by
... multiple datasets is likely to be due to some hidden biological phenomenon. Moreover, by selecting the genes responsible for the correlation, one can expect to select groups of genes which play a special role in or are affected by the underlying biological phenomenon. As an example, the existence of ...
... multiple datasets is likely to be due to some hidden biological phenomenon. Moreover, by selecting the genes responsible for the correlation, one can expect to select groups of genes which play a special role in or are affected by the underlying biological phenomenon. As an example, the existence of ...
Using metaMA for differential gene expression analysis from
... biological replicates available. Meta-analyses have increased sensitivity by combining different studies but it is expected that even more sensitivity can be obtained using shrinkage approaches when the number of samples is small in each individual study. metaMA proposes a method to calculate modera ...
... biological replicates available. Meta-analyses have increased sensitivity by combining different studies but it is expected that even more sensitivity can be obtained using shrinkage approaches when the number of samples is small in each individual study. metaMA proposes a method to calculate modera ...
Essential gene
Essential genes are those genes of an organism that are thought to be critical for its survival. However, being essential is highly dependent on the circumstances in which an organism lives. For instance, a gene required to digest starch is only essential if starch is the only source of energy. Recently, systematic attempts have been made to identify those genes that are absolutely required to maintain life, provided that all nutrients are available. Such experiments have led to the conclusion that the absolutely required number of genes for bacteria is on the order of about 250-300. These essential genes encode proteins to maintain a central metabolism, replicate DNA, translate genes into proteins, maintain a basic cellular structure, and mediate transport processes into and out of the cell. Most genes are not essential but convey selective advantages and increased fitness.