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The Role of Neurotrophins in Neurotransmitter Release
The Role of Neurotrophins in Neurotransmitter Release

No Slide Title
No Slide Title

... Are action potentials always propagated between cells? Action potentials in pre-synaptic terminal don’t always result in an action potential on the postsynaptic membrane… ________ ___________ ...
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Brain

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Neuroscience Journal Club
Neuroscience Journal Club

... • Hebb rule for Synaptic Plasticity (1946): synaptic facilitation can derive from each experience • The trace (persistence or repetition of a reverberatory activity) tends to induce lasting cellular changes that adds to its stability and that can be retrieved several years later through an electrica ...
Synapse and acetylcholine receptor synthesis by
Synapse and acetylcholine receptor synthesis by

... Three types of synapses were identified in the neurite regions. Conventional synapses (Fig. 5A) which resemble amacrineamacrine synapses of the intact retina and which are similar to those reported by Stefanelli et al. (2) were observed most frequently. At these synapses, synaptic vesicles were abun ...
Action potentials
Action potentials

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Chemical Messengers
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Anat 1: Ch 17 (SS99)

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Answer Key Chapter 28 - Scarsdale Public Schools

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Synaptic vesicles really do kiss and run
Synaptic vesicles really do kiss and run

... cells loaded with a fluorescent dye that accumulates in vesicles also illustrates allor-none exocytosis: the fluorescent vesicles can be seen to approach the plasma membrane and then completely lose their fluorescence7 (Fig. 1a). The kiss-and-run mechanism was clearly shown in mast cells by capacita ...
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STRUCTURE AND FUNCTION OF THE NERVOUS SYSTEM
STRUCTURE AND FUNCTION OF THE NERVOUS SYSTEM

... synapse: Mechanisms of neuromuscular transmission. Neuromuscular transmission disorders. The motor unit: concept. Neurotransmitter secretion: Transport of neurotransmitters and their precursors. Quantal neurotransmitter secretion: The role of calcium in neurotransmitter secretion. The synaptic vesic ...
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... stimulant that causes actual physical changes to the brain. It effects the level of dopamine in the brain and is highly addictive. Stimulants will increase the activity of the Central ...
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Chemical synapse



Chemical synapses are specialized junctions through which neurons signal to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to form circuits within the central nervous system. They are crucial to the biological computations that underlie perception and thought. They allow the nervous system to connect to and control other systems of the body.At a chemical synapse, one neuron releases neurotransmitter molecules into a small space (the synaptic cleft) that is adjacent to another neuron. The neurotransmitters are kept within small sacs called vesicles, and are released into the synaptic cleft by exocytosis. These molecules then bind to receptors on the postsynaptic cell's side of the synaptic cleft. Finally, the neurotransmitters must be cleared from the synapse through one of several potential mechanisms including enzymatic degradation or re-uptake by specific transporters either on the presynaptic cell or possibly by neuroglia to terminate the action of the transmitter.The adult human brain is estimated to contain from 1014 to 5 × 1014 (100–500 trillion) synapses. Every cubic millimeter of cerebral cortex contains roughly a billion (short scale, i.e. 109) of them.The word ""synapse"" comes from ""synaptein"", which Sir Charles Scott Sherrington and colleagues coined from the Greek ""syn-"" (""together"") and ""haptein"" (""to clasp""). Chemical synapses are not the only type of biological synapse: electrical and immunological synapses also exist. Without a qualifier, however, ""synapse"" commonly means chemical synapse.
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