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A Learning Rule for the Emergence of Stable Dynamics and Timing
A Learning Rule for the Emergence of Stable Dynamics and Timing

... FIG. 3. Recurrency and fixed synaptic ratios contribute to the lack of convergence. A: average number of spikes per cell (not Ai) over 2,000 training trials, in networks in which each neurons received 1 (black), 2 (red), or 4 (blue) from other excitatory neurons. With nEx 3 Ex ⫽ 1, synaptic scaling ...
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... to muscles and glands. Interneurons process the information from sensory neurons and send commands to other interneurons or motor neurons ...
Chem*3560 Lecture 26: Cell adhesion and membrane fusion
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... _____________ axon per cell arises from the axon hillock. (Slide 36) The end of the Axon can have 10,000 or more branches called ________________________. ...
Release of Acetylcholine: Signal at nerve terminal causes CA2+
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... 3- It should mimic the action of its presynaptic stimulation when applied postsynaptically. 4- It must have antagonists to prevent its effect. 5- There should be a mechanism available to terminate its effect. Therefore, the categories of neurotransmitters are classified according to the extent which ...
Abstract View OPTICAL RECORDING OF THE TRITONIA SWIMMING CENTRAL PATTERN GENERATOR. ;
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... We recorded action potential activity from the isolated brain of the nudibranch seaslug Tritonia diomedea during fictive swimming. Candidate central pattern generator (CPG) interneurons were identified by their bursting patterns and positions in the brain. Previously identifed populations of interne ...
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... simultaneously. (B) Region of the somatosensory cortex where lly imaged plane (coloured according to their orientation preference, c, Three-dimensional rendering of the arbors and cell bodies of functionally recordings were carried out. (C) Connectivity diagram of neurons in D. (D) as in Fig. 1b), a ...
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... Figure 9.5 Scheme showing functional roles of gap junction channels between astrocytes. Regions of highly active neurons release into the extracellular fluid that can induce hyperexcitability and neuronal apoptosis. Surrounding Astroglia take up both the K+ (blue dots) and glutamate (orange dots) e ...
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...  q(t) net charge inside the neuron at t  I(t) current of positive ions into neuron at t  g(v) conductance of membrane at voltage v  C capacitance of the membrane  Subscripts Na, K and L used to denote specific currents or conductances (L=“other”) ...
Q24 Describe the mechanism of action of the
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... mechanisms  above,  as  well  as  sedation,  euphoria  and  dysphoria  (likely  due  to  supraspinal  actions,  possibly  at  the   level  of  the  limbic  system).    The  euphoria  is  often  useful  in  attenuating  the  emotional  a ...


... the neural and immunological synapses is in the basic “wiring” of the systems. The central nervous system (CNS) is to a great extent hardwired and retains precise connectivity patterns throughout adult life, with neurons projecting long axonal processes that form synapses on complex dendritic trees ...
Nervous and Endocrine Systems
Nervous and Endocrine Systems

... • Allow messages to cross the synapse to the next neuron. • The synapse is the gap between two neurons. • Without neurotransmitters messages do not get sent or may not be received. ...
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indirect pathway

... Inhibits voltage-sensitive Ca2+ channels Activates K+ channels ...
Flyer
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... favoring ATP release and generation of preconditioning. If the stimulus is deleterious, microglia become overactivated and release bioactive molecules that increase the activity of hemichannels and reduce gap-junctional communication in astroglial networks, depriving neurons of astrocytic protective ...
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Neurons (aka Nerve Cells)

... Biology 12 The Nervous System ...
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Ch. 3 S. 1

... hand, yawns, or thinks about a friend, neurotransmitters are involved. Some diseases and psychological disorders may also be caused by the presence of too much or too little of various neurotransmitters. Researchers have identified dozens of neurotransmitters and their functions. Examples: noradrena ...
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LTP

... • "when an axon of cell A ... excite a cell B and repeatedly or persistently takes part in firing it, some growth process or metabolic change takes place in one or both cells such that A's efficiency, as one of the cells firing B, is increased" (Hebb, 1949) • Cells that fire together, wire together ...
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Chemical synapse



Chemical synapses are specialized junctions through which neurons signal to each other and to non-neuronal cells such as those in muscles or glands. Chemical synapses allow neurons to form circuits within the central nervous system. They are crucial to the biological computations that underlie perception and thought. They allow the nervous system to connect to and control other systems of the body.At a chemical synapse, one neuron releases neurotransmitter molecules into a small space (the synaptic cleft) that is adjacent to another neuron. The neurotransmitters are kept within small sacs called vesicles, and are released into the synaptic cleft by exocytosis. These molecules then bind to receptors on the postsynaptic cell's side of the synaptic cleft. Finally, the neurotransmitters must be cleared from the synapse through one of several potential mechanisms including enzymatic degradation or re-uptake by specific transporters either on the presynaptic cell or possibly by neuroglia to terminate the action of the transmitter.The adult human brain is estimated to contain from 1014 to 5 × 1014 (100–500 trillion) synapses. Every cubic millimeter of cerebral cortex contains roughly a billion (short scale, i.e. 109) of them.The word ""synapse"" comes from ""synaptein"", which Sir Charles Scott Sherrington and colleagues coined from the Greek ""syn-"" (""together"") and ""haptein"" (""to clasp""). Chemical synapses are not the only type of biological synapse: electrical and immunological synapses also exist. Without a qualifier, however, ""synapse"" commonly means chemical synapse.
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