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Optimization of neuronal cultures derived from human
Optimization of neuronal cultures derived from human

... presynaptic proteins and the sypHy reporter. Reporter Viral Transduction. For analysis of presynaptic function, cultures were infected with an adeno-associated virus (AAV) used to deliver a synaptophysin-pHluorin fusion fluorescent reporter construct (sypHy). The synaptophysin-pHluorin reporter and ...
A Simple Biophysically Plausible Model for Long Time
A Simple Biophysically Plausible Model for Long Time

... perfect integrator with an infinite time constant; the basic idea of this article is to use a similar approach to generate leaky integrators with a range of finite time constants. We show that for a realistic choice of the parameters the firing rate decays approximately exponentially. The time const ...
Where is Pain Percieved?
Where is Pain Percieved?

... Pain is an inescapable sensation that every human being has experienced at least once in their lifetimes. The sensation of pain has two ways of being graded on its severity. The first is the objective intensity of pain, and the second is the subjective pain that the subject feels. Pain is one of the ...
Text S1.
Text S1.

... axonal polarization along L1 at 3 DIV but, initially, any of the 4 growing neurites could have differentiated into an axon. The discrepancy between random choice at 1-2 DIV and axonal preference along L1 at 3 DIV corresponds to failures of polarization along curved lines. It is thus possible to calc ...
Optical Illusion - CS 229: Machine Learning
Optical Illusion - CS 229: Machine Learning

... The goal of this project is to explain some of the illusory phenomena using sparse coding and whitening model. Instead of the sparse coding method proposed by Olshausen in [1], transient invariant sparse coding is used. Transient in variant sparse coding can learn larger bases compared to ordinary s ...
UNIT 4 – HOMEOSTASIS 8.1 – Human Body Systems and H
UNIT 4 – HOMEOSTASIS 8.1 – Human Body Systems and H

... to dilate  this increases blood flow to the surface of the skin. The warm blood heats up the sweat droplets on the surface of the skin and loses heat to evaporate them, returning to the core of the body much cooler. Unfortunately, sweat carries valuable salts with it, so when the body sweats, it lo ...
Sensory systems
Sensory systems

... • stimuli arriving through the sensory systems might induce reflexes at the level of the spinal cord, brain stem or cortex • we can become conscious of incoming information, it may be stored in the form of memory and it can evoke emotional reactions • the prerequisite to become aware of a stimulus i ...
The cells of the nervous system
The cells of the nervous system

... – re-uptake - this occurs with norepinephrine, which is reabsorbed by presynaptic membrane. • The continual synthesis and removal of neurotransmitters requires a very large amount of energy. • Neurones contain a large number of mitochondria to provide ATP. • This is why the brain is so easily damage ...
Frog Vision
Frog Vision

... • The four tectal sheets of neurons essentially provide a recoding of the retinal image. • The retinal image is specified in terms of luminance at each receptor - this description is redundant and not useful to frog. • Tectal neurons recode each small region on retina in terms of 4 basic features or ...
Neuromuscular Adaptations During the Acquisition of Muscle
Neuromuscular Adaptations During the Acquisition of Muscle

... the Acquisition of a Motor Task • The results showed much less variability in force at 60 % MVC • At 60 % MVC, changes in firing rate give much better control of force than would recruitment. • IIa or IIb when recruited would result in large force variations • Significant increases in MPF after exte ...
Electrophysiological recordings from behaving animals—going
Electrophysiological recordings from behaving animals—going

... The availability of high dimensional data also requires analysis tools that enable extraction of high order interaction between the recorded units (for review see [24] and [25]). Another direction is trying to extrapolate information on intrinsic properties of the units from extracellular waveforms ...
Sensory systems - somatosensation
Sensory systems - somatosensation

... • stimuli arriving through the sensory systems might induce reflexes at the level of the spinal cord, brain stem or cortex • we can become conscious of incoming information, it may be stored in the form of memory and it can evoke emotional reactions • the prerequisite to become aware of a stimulus i ...
A Point Process Model for Auditory Neurons Considering
A Point Process Model for Auditory Neurons Considering

... containing the most salient factors to neural spiking activity and use the fitted model to evaluate the relative importance of the factors. Two key factors or covariates to consider in standard neurophysiology experiments are the intrinsic dynamics of the neuron such as the absolute and relative ref ...
PDF of article - Janelia Research Campus
PDF of article - Janelia Research Campus

... hand side of Figure 2f to b). LPTCs, however, still respond to both rotation and translation of the fly, whereas the gaze-stabilization system is primarily tuned for rotations [12]. This ambiguity is partially resolved by neck motor neurons (NMNs) [31!] and some descending neurons (DNs) [32] which i ...
Rapid Taste Responses in the Gustatory Cortex
Rapid Taste Responses in the Gustatory Cortex

... returned to baseline in tens of milliseconds. Tastant-responsive neurons were broadly tuned and responded to increasing tastant concentrations by either increasing or decreasing their firing rates. In addition, some responses were only evoked at intermediate tastant concentrations. In summary, these ...
Rapid Taste Responses in the Gustatory Cortex during Licking
Rapid Taste Responses in the Gustatory Cortex during Licking

Large-scale spatiotemporal spike patterning consistent with
Large-scale spatiotemporal spike patterning consistent with

... labelled above each plot is with respect to the onset of the visual target. The red arrow in the bottom right panel shows the propagation direction of the wave. (b) Temporal evolution of the GOF measure of planar wave activity (PGD in blue ranging from 0.295 to 0.335, as well as the mean hand speed ...
Reconstruction of Natural Scenes from Ensemble Responses in the
Reconstruction of Natural Scenes from Ensemble Responses in the

SENSORY SYSTEMS
SENSORY SYSTEMS

Nervous System - Serrano High School AP Biology
Nervous System - Serrano High School AP Biology

... rabies virus is transported this way through the PNS neurons to the CNS neurons to the brain. Neural impulses are transmitted both chemically and electrically. This can happen because the cell membrane has the ability to pump out certain molecules that have an electrical charge and allow other charg ...
neural basis of deciding, choosing and acting
neural basis of deciding, choosing and acting

... brain processes and associated body movements ‘happening’ from the agent ‘acting’? To answer this question, we must understand the basic properties of decisions, choices and actions, and how they arise from brain processes. We are beginning to reach such a level of understanding of how the brain mak ...
Biology 2401 Anatomy and Physiology I notes
Biology 2401 Anatomy and Physiology I notes

... - synapse between neuron and other cells called neuro____ junction (for example with muscle cell it is called neuromuscular junction) - axons branch and each branch ends in an expanded tip called a synaptic terminal or synaptic knob ( maybe as many as 1,000) - synaptic knobs contain membrane sacs ca ...
fluctuations in somatosensory responsiveness and baseline firing
fluctuations in somatosensory responsiveness and baseline firing

... administered in the second group of experiments (N⫽30 neurons). In the third group, injection manipulations with the empty device on the rat’s head were simulated (N⫽24 neurons). The latter two groups did not statistically differ from each other in any parameter, which made it possible to combine th ...
temporal visual event recognition
temporal visual event recognition

... in the ventral visual pathway [2]. How the brain creates prediction signals in general relates to the fundamental question of how the brain represents time. Buonomano [4] discussed the two prevalent views of how this may be – “labeled lines”, in which each neuron’s firing can represent events on dif ...
Spinal Cord and Spinal Nerves
Spinal Cord and Spinal Nerves

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Neural coding

Neural coding is a neuroscience-related field concerned with characterizing the relationship between the stimulus and the individual or ensemble neuronal responses and the relationship among the electrical activity of the neurons in the ensemble. Based on the theory thatsensory and other information is represented in the brain by networks of neurons, it is thought that neurons can encode both digital and analog information.
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