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Axonal conduction properties of antidromically identified neurons in
Axonal conduction properties of antidromically identified neurons in

... of neurons outside of layer IV, particularly those in layers V and VI. One such approach for distinguishing among different local circuits in these layers may be to identify the projection target of neurons whose axon collaterals contribute to the local network. In vivo, this can be accomplished usi ...
Mechanism for propagation of rate signals through a 10
Mechanism for propagation of rate signals through a 10

... can exhibit coherence resonance in response to noise only.[8] Here, the mean firing rate of layer 2, f2 is a single-peaked function of τsyn , with a maximum at τsyn = 3 ms. Accordingly, the output rate is also peaked at τsyn = 3 ms, suggesting that the propagation of rate signals can be modulated by ...
Enhanced intrinsic excitability and EPSP
Enhanced intrinsic excitability and EPSP

... Running head: Environmental enrichment and hippocampal plasticity Keywords: Contextual fear learning; action potential threshold; theta-burst stimulation; miniature excitatory postsynaptic currents, after-hyperpolarization ...
Interactions between Adjacent Ganglia Bring About the Bilaterally
Interactions between Adjacent Ganglia Bring About the Bilaterally

... mM HEPES (pH 7.4)] to which 10 mM glucose was added. Nerve cords were treated for 3-5 min at room temperature with 0.25% collagenase (Sigma, type I) in this same solution to soften the ganglion capsule for microelectrode penetration, then washed. Neuronal cell bodies were visualized with Nomarski op ...
Wider Than the Sky: The Phenomenal Gift of Consciousness
Wider Than the Sky: The Phenomenal Gift of Consciousness

... ent areas of the brain. That an area may be essential or necessary for consciousness does not mean it is sufficient. Furthermore, a given neuron may contribute to conscious activity at one moment and not at the next. There are a number of other important aspects of consciousness as a process that m ...
The basic Hebb rule
The basic Hebb rule

... enhancement or depression of particular inputs to intercalated neurons is accompanied by inverse modifications at heterosynaptic sites, which contributes to total synaptic weight ...
Your Brain
Your Brain

... Manipulating the Brain Now, however, scientists need not wait for brain injuries to occur randomly. They can electrically stimulate the brain. Or they can surgically produce a brain lesion (destruction of tissue) in specific brain areas in animals. For example, a lesion in one well-defined region of ...
The Journal of Neuroscience, June 1, 2003 • 23(11):4657– 4666
The Journal of Neuroscience, June 1, 2003 • 23(11):4657– 4666

... Ilan A. Kerman1,2,3 Lynn W. Enquist,4 Stanley J. Watson,3 and Bill J. Yates Previous physiological investigations have suggested the existence of a neural circuit that coordinates activation of motor and autonomic efferents before or at the onset of exercise. Traditionally these circuits have been p ...
Chapter 2: The Brain and Behavior
Chapter 2: The Brain and Behavior

... scale is exaggerated here. Such measurements require ultra-small electrodes, as described later in this chapter.) The inside of an axon at rest is about -60 to -70 millivolts, compared with the outside. Electrochemical changes in a neuron generate an action potential. When positively charged sodium ...
MS Word Version - Interactive Physiology
MS Word Version - Interactive Physiology

... a. The binding of ACh opens ion channels in the dendrites or cell body that permits both _______ and ____________ to move through them. b. Which ion would move into the cell? ______________ out of the cell? ______________ c. Which ion has the greatest electrochemical gradient? ______________ d. The ...
Early Neural Patterning •Neural induction
Early Neural Patterning •Neural induction

... -In albino amphibian embryos, every single cell is non-pigmented (tagging of cell possible to trace lineage) -Noted tissue immediately adjacent to dorsal lip of blastula is important → dorsal mesoderm -Transplant donor tissue to where ventral mesoderm is in the recipient embryo -Recipient has 2 patc ...
Synchronization and coordination of sequences in two neural
Synchronization and coordination of sequences in two neural

... 共Received 12 August 2004; published 21 June 2005兲 There are many types of neural networks involved in the sequential motor behavior of animals. For high species, the control and coordination of the network dynamics is a function of the higher levels of the central nervous system, in particular the c ...
Metabolic acidosis inhibits hypothalamic warm
Metabolic acidosis inhibits hypothalamic warm

... (11). Do metabolic disturbances in acid-base balance alter various behavioral and physiological mechanisms of thermoregulation? For example, are there differences in the effects of hypercapnic acidosis or metabolic acidosis on evaporative heat loss versus increased skin blood flow? At the cellular l ...
Voltage-Gated Ion Channels and the Propagation of Action
Voltage-Gated Ion Channels and the Propagation of Action

... and the Propagation of Action Potentials in Nerve Cells In the previous section, we examined how different transport proteins work together to absorb nutrients across the intestinal epithelium and to acidify the stomach. The nervous system, however, provides the most striking example of the interpla ...
Endocrine and nervous systems
Endocrine and nervous systems

... 9. A person with a vitamin A deficiency may have night blindness. The glare from the headlights of an approaching car will temporarily reduce that person’s visual capacity. The primary structures associated with this change are the A. B. C. D. ...
Methods of Studying The Nervous System - U
Methods of Studying The Nervous System - U

... horizontal sections where radio-activity has accumulated, and thus it indicates what areas were particularly active during the test Pinel's Biopsychology, 5th Ed. ...
1 The Brain and Behavior
1 The Brain and Behavior

... Two Opposing Views Have Been Advanced on the Relationship Between Brain and Behavior Our current views about nerve cells, the brain, and behavior have emerged over the last century from a convergence of five experimental traditions: anatomy, embryology, physiology, pharmacology, and psychology. Befo ...
embj201488977-sup-0010-Suppl
embj201488977-sup-0010-Suppl

... engagement in CRH neurons. (A) Secretagogin can affect CRH release either indirectly, by affecting the function of key proteins involved in the vesicle formation and cargo along the axons to the median eminence (“vesicle logistics”), or more directly, by Ca2+-dependent modulation of the exocytosis m ...
High-performance genetically targetable optical neural
High-performance genetically targetable optical neural

... tolerated because pH excursions created by Arch illumination are minimized by self-limiting mechanisms to levels comparable to those mediated by channelrhodopsins2,3 or natural spike firing. To highlight how proton pump ecological and genomic diversity may support new innovation, we show that the bl ...
Nervous System - Princeton ISD
Nervous System - Princeton ISD

... Axosomatic – synapses between the axon of one neuron and the soma of another Other types of synapses include: ...
brain –computer interface - Nexus Academic Publishers
brain –computer interface - Nexus Academic Publishers

... materECoG is a very promising intermediate BCI modality because it has higher spatial resolution, better signal-to-noise ratio, wider frequency range, and lesser training requirements than scalp-recorded EEG, and at the same time has lower technical difficulty, lower clinical risk, and probably sup ...
Project Report: Investigating topographic neural map development
Project Report: Investigating topographic neural map development

... where r0 is some bias spontaneous firing rate and F represents, at minimum, a rectifying function, but it usually involves a more sophisticated manipulation by processing it through an integrate and fire (IAF) neuron model, Hodgkin-Huxley model, or some variant of a stochastic process (e.g. Poisson) ...
Millisecond-Timescale Optical Control of Neural Dynamics in the
Millisecond-Timescale Optical Control of Neural Dynamics in the

... promoter enables cell-specific targeting and efficient expression of ChR2-GFP in excitatory neurons of the monkey frontal cortex. Given the extended duration of nonhuman primate experiments, and the prospect of using cell-specific optical neuroprosthetics for therapy, we assessed the safety of ChR2- ...
Harris KD. Neural signatures of cell assembly organization. Nat Rev
Harris KD. Neural signatures of cell assembly organization. Nat Rev

... is no causal influence from one brain to the other, the response of two neurons recorded in the two brains will be independent, for any given stimulus presentation (conditional independence). Nevertheless, because both animals experience the same stimuli, an overall correlation (marginal dependence) ...
The 18th European Conference on Artificial - CEUR
The 18th European Conference on Artificial - CEUR

... Space, 2008] games engine. It is a black and white 3D environment with an agent, a user, four rooms connected by four corridors, and a unique object in each room (see Figure 4); the objects were vertically or horizontally striped pyramids or stalactites (down facing pyramids). The agent and user can ...
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Single-unit recording

In neuroscience, single-unit recordings provide a method of measuring the electro-physiological responses of single neurons using a microelectrode system. When a neuron generates an action potential, the signal propagates down the neuron as a current which flows in and out of the cell through excitable membrane regions in the soma and axon. A microelectrode is inserted into the brain, where it can record the rate of change in voltage with respect to time. These microelectrodes must be fine-tipped, high-impedance conductors; they are primarily glass micro-pipettes or metal microelectrodes made of platinum or tungsten. Microelectrodes can be carefully placed within (or close to) the cell membrane, allowing the ability to record intracellularly or extracellularly.Single-unit recordings are widely used in cognitive science, where it permits the analysis of human cognition and cortical mapping. This information can then be applied to brain machine interface (BMI) technologies for brain control of external devices.
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