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TUSSIONEX Pennkinetic (hydrocodone polistirex
TUSSIONEX Pennkinetic (hydrocodone polistirex

... used with caution in elderly or debilitated patients and those with severe impairment of hepatic or renal function, hypothyroidism, Addison's disease, prostatic hypertrophy, or urethral stricture. The usual precautions should be observed and the possibility of respiratory depression should be kept i ...
Name: Paracetamol
Name: Paracetamol

... for their children and also when to seek medical attention. It is clearly stated on the pack that the medication is not to be used for more than 48 hours without seeking medical advice and dose should be given every 4 to 6 hours as required with not more than 4 doses in 24 hours. This change also me ...
Phytochemicals for Diabetes Management
Phytochemicals for Diabetes Management

... from the roots of Talinum paniculatum Gaertner (Portulacaceae). These alkaloids are the inhibitors of TNF- production by macrophages and fat cells. It has also been reported that T. paniculatum is useful as a dietary supplement and for the prevention of diabetes [26, 27]. Lepidine and semilepidine, ...
CLARITIN® Rapid Dissolve
CLARITIN® Rapid Dissolve

... Loratadine is a long-acting tricyclic antihistamine with selective peripheral H 1 receptor antagonistic activity. It exhibits a dose-related inhibition of the histamine-induced skin wheal and flare response in humans which is rapid in onset, is apparent at two hours and persists throughout the 24 ho ...
Opioid Tolerance and Dependence in Infants and Children
Opioid Tolerance and Dependence in Infants and Children

... affect a decrease in the action potential duration and a decrease in neurotransmitter release. Activation of these intracellular events results analgesia.(6,7) A tolerance/hyperalgesia cascade occurs at a thousand fold lower (pM-nM) concentrations, Opioid agonists have been shown to elicit an excita ...
Cardiovascular Active Medications
Cardiovascular Active Medications

... • Many drugs are used to manage hemodynamic before, during and after any operation ...
AAPM Report No 121
AAPM Report No 121

... persons, to review applications for human investigational studies. The Board weighs the safety of the study with the benefit that might come from the study. The protocol, consent procedure, and evaluation methodology must all be approved for any research using human subjects. When medical products a ...
Diabetes Mellitus (DM) PHCL 442
Diabetes Mellitus (DM) PHCL 442

... action of short & intermediate acting insulin administered at different times of the day • This enables the clinician to evaluate the effect of various insulin components on meals & to identify nocturnal hypoglycemia ...
- Thieme Connect
- Thieme Connect

... comparison to the placebo group with respect to NYHA functional classification, LVEF, 6-min walking distance, and quality of life. The detailed mechanism of the qili-qiangxin capsule in treating heart failure is not well established yet. An animal study showed that the qili-qiangxin capsule could do ...
Two Brain Sites for Cannabinoid Reward
Two Brain Sites for Cannabinoid Reward

... strations of rewarding effects of ⌬9THC appear to be very much dependent on the experimental conditions (Parolaro et al., 2005), the brain sites at which ⌬9THC can trigger these actions are not known. In the present study, we used microinjections into subregions of the VTA and nucleus accumbens to d ...
Zopiclone Orion film-coated tablet ENG PL
Zopiclone Orion film-coated tablet ENG PL

... rebound symptoms (see section 2, Warnings and precautions). You should not take Zopiclone Orion for longer than 4 weeks including the tapering off phase. Ask your doctor for advice if your symptoms do not improve within this period. If you take more Zopiclone Orion than you should If you have taken ...
paper of Dermatophyte Nail Infection-nowrozi_h-2013-01-07
paper of Dermatophyte Nail Infection-nowrozi_h-2013-01-07

... not used in a widespread way.12 Ketoconazole was the first orally active imidazole but it is known for its hepatotoxicity as well.7 Terbinafine is highly effective against dermatophyte infections and acts by blocking ergosterol synthesis.10 ...
Canine idiopathic epilepsy - Veterinary Ireland Journal
Canine idiopathic epilepsy - Veterinary Ireland Journal

... frequent than every two months. Treatment should also be started if there is a trend towards more frequent or severe seizures. Epilepsy is a progressive disorder and repeated seizures damage the brain making further seizures more likely (Sakurai and others 2013). The number and frequency of seizures ...
Pseudomonas aeruginosa infection in cystic fibrosis Infection and Drug Resistance Dove
Pseudomonas aeruginosa infection in cystic fibrosis Infection and Drug Resistance Dove

... patients. Aminoglycosides have been widely studied trying to optimize their therapeutic concentrations and minimize ­toxicity. The bactericidal efficacy of this antibiotic family is peak dependent (postdose drug concentration) while the main adverse effects such as nephrotoxicity are trough dependen ...
PRODUCT MONOGRAPH ACCUTANE™ ROCHE isotretinoin
PRODUCT MONOGRAPH ACCUTANE™ ROCHE isotretinoin

... small or absent external auditory canals, microphthalmia, facial dysmorphia, cleft palate); cardiac (septal defects, aortic arch abnormalities, tetralogy of Fallot); thymus gland abnormalities; and parathyroid hormone deficiency. Cases of IQ scores less than 85 with or without other abnormalities ha ...
Importance of NMDA Receptor Activation During Initial
Importance of NMDA Receptor Activation During Initial

... response is the product of a complex and well‐regulated set of processes in the body  that assist in coping with the stress in an adaptive manner.  Two endocrine systems  in the body react to a stress stimulus.  The sympathetic nervous system (SNS)  stimulates release of epinephrine from the adrenal ...
Protective Effect of Honey on Acetaminophen Induced Liver Toxicity
Protective Effect of Honey on Acetaminophen Induced Liver Toxicity

... al., 2007). However, since some of these diseases are a consequence of oxidative damage, it seems that part of the therapeutical properties of honey products is due to their antioxidant capacity (Hegazi and Abd El-Hady, 2009). Furthermore, honey as a source of antioxidants, has been proven to be eff ...
Self-Learning Module Added Nursing Competency Patient
Self-Learning Module Added Nursing Competency Patient

Diapositive 1
Diapositive 1

... a 32-yr old woman treated for GD with PTU (200 mg/d) for 3-4 months before developing acute liver failure. Upon hospitalization, it was found that she was 10week pregnant. Outcome: death. Personal Note: I was disappointed by the paucity of cases related to pregnancy. The 2 patients are almost incide ...
14. Narayanan S. et al. Antioxidant activities of Seabuckthorn
14. Narayanan S. et al. Antioxidant activities of Seabuckthorn

... the serum levels of LN (Laminin), HA (Hyaluronic acid), collagen types III and IV, total bile acid (TBA). So Seabuckthorn may be a hopeful drug for prevention and treatment of liver fibrosis.25 ...
Recent advances in knowledge about beta
Recent advances in knowledge about beta

... beta-adrenergic receptors appear to be distinct molecular entities (29). Biochemical studies, therefore, have verified at the molecular level the concept of beta-adrenergic receptor subtypes that was originally deduced only from indirect pharmacologic studies. Elucidation of changes in responsivenes ...
DOCEtaxel - Cancer Care Ontario
DOCEtaxel - Cancer Care Ontario

... Docetaxel-induced fluid retention is cumulative in severity and incidence, generally reversible but may be severe with ascites, pleural or pericardial effusions.  Peripheral edema can be treated with standard measures (e.g. sodium restriction, diuretics).  Premedication with oral corticosteroids has ...
Inhibition of N-Nitrosodimethylamine Metabolism
Inhibition of N-Nitrosodimethylamine Metabolism

... studied the blood concentration appeared to decline in a concentrations obtained by extrapolating the data to time zero monoexponential manner with an initial concentration of approx were similar for the 2 groups. This indicates that brief ether imately 0.4 ^g/ml and a half-life of 11 min. The calcu ...
Note for Guidance on Pk in renal impairment
Note for Guidance on Pk in renal impairment

... A pharmacokinetic study in patients with impaired renal function is recommended when renal impairment is likely to significantly alter the pharmacokinetics of the drug and/or its active metabolites and a posology adjustment may be needed for such patients taking into account the PK/PD relationship. ...
Studies on Variability in Olanzapine Disposition  
Studies on Variability in Olanzapine Disposition  

... collected from 29 out of them. Because of very low OLA and DMO concentrations in CSF, a new liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for determination of OLA and DMO in serum and CSF was developed. We found a strong correlation between serum and CSF concentrations of OLA and ...
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Bilastine



Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
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