Clinical and experimental studies on theophylline
... Reverse Pharmacology • Experimental evaluation/documentation of clinically observed findings • Reverse pharmacology is an alternative strategy for new drug development • Reverse pharmacology can play an important role in safety pharmacology studies ...
... Reverse Pharmacology • Experimental evaluation/documentation of clinically observed findings • Reverse pharmacology is an alternative strategy for new drug development • Reverse pharmacology can play an important role in safety pharmacology studies ...
Population Pharmacokinetic Evaluation of Eslicarbazepine Acetate
... Statement of Purpose, Innovation or Hypothesis: Eslicarbazepine acetate (ESL), a once-daily antiepileptic drug (AED), is converted to eslicarbazepine, the primary active metabolite of ESL, after oral administration. The population pharmacokinetics (PK) of eslicarbazepine were investigated, including ...
... Statement of Purpose, Innovation or Hypothesis: Eslicarbazepine acetate (ESL), a once-daily antiepileptic drug (AED), is converted to eslicarbazepine, the primary active metabolite of ESL, after oral administration. The population pharmacokinetics (PK) of eslicarbazepine were investigated, including ...
Anabolic Laboratories : Policosanol
... inspected pharmaceutical facility. Our in-house laboratories and manufacturing facilities are routinely inspected by the United States Food and Drug Administration (FDA) and Drug Enforcement Administration (DEA). We also maintain a Good Manufacturing Practice (GMP) certification from the Natural Pro ...
... inspected pharmaceutical facility. Our in-house laboratories and manufacturing facilities are routinely inspected by the United States Food and Drug Administration (FDA) and Drug Enforcement Administration (DEA). We also maintain a Good Manufacturing Practice (GMP) certification from the Natural Pro ...
Review of Psychotropic Drugs 2009
... is aware of the need to avoid consuming such drugs as those containing dextromethorphan (Robitussin©), nasal decongestants, hay-fever, sinus, and asthma medication; and foods with high tyramine or dopamine content such as beer, wine (including those that have little-to-no alcohol), pickled herring, ...
... is aware of the need to avoid consuming such drugs as those containing dextromethorphan (Robitussin©), nasal decongestants, hay-fever, sinus, and asthma medication; and foods with high tyramine or dopamine content such as beer, wine (including those that have little-to-no alcohol), pickled herring, ...
Bridion (sugammadex)
... Used for adults undergoing general surgery for the reversal of neuromuscular blockade induced by vecuronium or rocuronium Hypersensitivity to sugammadex or any component of the product None Use not recommended with severe renal impairment or dialysisdependent patients Pregnancy: no adequate or well- ...
... Used for adults undergoing general surgery for the reversal of neuromuscular blockade induced by vecuronium or rocuronium Hypersensitivity to sugammadex or any component of the product None Use not recommended with severe renal impairment or dialysisdependent patients Pregnancy: no adequate or well- ...
appendix - iii
... anesthesia. The study consists of 120 women were allocated randomly to one of three groups (n = 40 in each) to receive saline (control), 0.1 mg oral ramosetron (PO), or 0.3 mg IV ramosetron (IV). Total intravenous anesthesia (TIVA) with propofol and remifentanil was used in all patients. The results ...
... anesthesia. The study consists of 120 women were allocated randomly to one of three groups (n = 40 in each) to receive saline (control), 0.1 mg oral ramosetron (PO), or 0.3 mg IV ramosetron (IV). Total intravenous anesthesia (TIVA) with propofol and remifentanil was used in all patients. The results ...
ARBS (if unable to tolerate ACE`s) with evidence in Heart Failure
... Remember: Patients who are clinically “dry” may be more prone to renal failure when ACE/ARB dose is up‐titrated ...
... Remember: Patients who are clinically “dry” may be more prone to renal failure when ACE/ARB dose is up‐titrated ...
- Minapharm Pharmaceuticals
... with diabetes mellitus and alcoholic liver disease. In noninsulin dependent diabetes mellitus (type 2) and associated chronic liver disease, plasma levels of glucose, insulin, and triglycerides are high, with increased lipid peroxidation and reduction in natural antioxidant reserves. It was hypothes ...
... with diabetes mellitus and alcoholic liver disease. In noninsulin dependent diabetes mellitus (type 2) and associated chronic liver disease, plasma levels of glucose, insulin, and triglycerides are high, with increased lipid peroxidation and reduction in natural antioxidant reserves. It was hypothes ...
Familial Cold Autoinflammatory Syndrome
... FCAS, but can also be triggered by other stimuli. In most cases, MWS patients develop progressive hearing loss. In some MWS cases amyloidosis develops later in life, a disease in which an abnormal accumulation of the protein amyloid occurs in a patient's tissues and organs. Accumulation of amyloi ...
... FCAS, but can also be triggered by other stimuli. In most cases, MWS patients develop progressive hearing loss. In some MWS cases amyloidosis develops later in life, a disease in which an abnormal accumulation of the protein amyloid occurs in a patient's tissues and organs. Accumulation of amyloi ...
Complex Cases-Neurology_handout
... Parkinson’s disease case continued… After an additional two years, the clinic receives a call from the patient’s husband stating that she keeps telling him that her mother (who has been deceased for 11 years) has been visiting her in the evenings. HB is very distressed by these visits, and becomes ...
... Parkinson’s disease case continued… After an additional two years, the clinic receives a call from the patient’s husband stating that she keeps telling him that her mother (who has been deceased for 11 years) has been visiting her in the evenings. HB is very distressed by these visits, and becomes ...
What`s the Latest in Stable Ischemic Heart Disease?
... hypertension, diabetes mellitus, LV systolic dysfunction, or CKD and have indications for, but are intolerant of, ACE inhibitors. (Level of Evidence: A) ...
... hypertension, diabetes mellitus, LV systolic dysfunction, or CKD and have indications for, but are intolerant of, ACE inhibitors. (Level of Evidence: A) ...
or Nicotine Exposure in Adult Male
... a role in inducing dependence to smoking. Animals also show upregulation of nAChRs after chronic nicotine exposure. However, these studies use nicotine alone to model tobacco dependence, ignoring the other 8,000 constituents found in cigarette smoke whose contribution to tobacco dependence have not ...
... a role in inducing dependence to smoking. Animals also show upregulation of nAChRs after chronic nicotine exposure. However, these studies use nicotine alone to model tobacco dependence, ignoring the other 8,000 constituents found in cigarette smoke whose contribution to tobacco dependence have not ...
ascot-lla
... with or at high risk of CVD; in HPS 6, simvastatin 40mg daily reduced MI & non-fatal CHD in elderly male patients (age 40-80yrs) morbidity & mortality in male and female patients with or at high risk of CVD. ♦ ASCOT-LLA supports the use of atorvastatin 10mg daily for primary prevention of CHD & stro ...
... with or at high risk of CVD; in HPS 6, simvastatin 40mg daily reduced MI & non-fatal CHD in elderly male patients (age 40-80yrs) morbidity & mortality in male and female patients with or at high risk of CVD. ♦ ASCOT-LLA supports the use of atorvastatin 10mg daily for primary prevention of CHD & stro ...
Antibiotic Safety Assessment
... adverse reactions are identified and investigated. Some are well known, such as the hydroxylamine metabolite of chloramphenicol (responsible for bone marrow aplasia in one in 20 000 treated patients), and quinoneimine, the toxic metabolite of amodiaquine. Use of this latter antimalarial saw a reviva ...
... adverse reactions are identified and investigated. Some are well known, such as the hydroxylamine metabolite of chloramphenicol (responsible for bone marrow aplasia in one in 20 000 treated patients), and quinoneimine, the toxic metabolite of amodiaquine. Use of this latter antimalarial saw a reviva ...
Comparative effects of levosimendan and
... Aim: We aimed to evaluate the comparative effects of levosimendan and dobutamine on P-wave dispersion (PWD) in the patients with acute decompensated heart failure (ADHF). Materials and methods: The study population consisted of 40 patients (mean age = 68 years, 23 men, NYHA class IIIIV) presented wi ...
... Aim: We aimed to evaluate the comparative effects of levosimendan and dobutamine on P-wave dispersion (PWD) in the patients with acute decompensated heart failure (ADHF). Materials and methods: The study population consisted of 40 patients (mean age = 68 years, 23 men, NYHA class IIIIV) presented wi ...
Rivaroxaban—Once daily, oral, direct factor Xa
... required with rivaroxaban. Results from the phase III RECORD program, which investigated rivaroxaban for the prevention of venous thromboembolism (VTE) after total hip replacement (THR) and total knee replacement (TKR), demonstrated that rivaroxaban, 10 mg od, was significantly superior to enoxapari ...
... required with rivaroxaban. Results from the phase III RECORD program, which investigated rivaroxaban for the prevention of venous thromboembolism (VTE) after total hip replacement (THR) and total knee replacement (TKR), demonstrated that rivaroxaban, 10 mg od, was significantly superior to enoxapari ...
Use of Tantum Rosa - 2008 Elisad Meeting
... Overall, these phases last for about 6…8 hours, with a possible slight revival in the next day Music seems to dramatically increase the effects; recommended music – psychedelic The memory seems to be able to trace up to 100% of these experiences; still, this figure decreases with the dose of Tantum ...
... Overall, these phases last for about 6…8 hours, with a possible slight revival in the next day Music seems to dramatically increase the effects; recommended music – psychedelic The memory seems to be able to trace up to 100% of these experiences; still, this figure decreases with the dose of Tantum ...
DRUG NAME : Clexane (enoxaparin) Pre
... clexane and its inactivation, if it were taken orally its absorption into breast milk will be insignificant. For comprehensive information please refer to the current British National Formulary and Summary of Product Characteristics. SHARED CARE Shared care guideline: is a document which provides in ...
... clexane and its inactivation, if it were taken orally its absorption into breast milk will be insignificant. For comprehensive information please refer to the current British National Formulary and Summary of Product Characteristics. SHARED CARE Shared care guideline: is a document which provides in ...
Clinical Focus - Orbis Biosciences
... The results of the study showed that Orbis’ liquid formulation and powder formulation were preferable over the reference listed drug (Roxane Liquid) in every category, especially taste. The main conclusion of the report was that the Orbis powder and the Placebo (which was an Orbis microsphere with n ...
... The results of the study showed that Orbis’ liquid formulation and powder formulation were preferable over the reference listed drug (Roxane Liquid) in every category, especially taste. The main conclusion of the report was that the Orbis powder and the Placebo (which was an Orbis microsphere with n ...
What is SierraSil
... Mountain Minerals, Inc. Joint or Joint Plus Formulas. We recommend that you take the capsules on an empty stomach, at least one-half before or one hour after meals. Return to Top 7. Are there any human clinical trials involving SierraSil? Yes. SierraSil has been used in a number of clinical trials, ...
... Mountain Minerals, Inc. Joint or Joint Plus Formulas. We recommend that you take the capsules on an empty stomach, at least one-half before or one hour after meals. Return to Top 7. Are there any human clinical trials involving SierraSil? Yes. SierraSil has been used in a number of clinical trials, ...
Diltiazem - The Royal Children`s Hospital
... Diltiazem helps to reduce blood pressure by relaxing and widening blood vessels. It also helps the heart to pump more effectively. It is also sometimes used it to increase cyclosporin levels. HOW TO TAKE THIS MEDICINE Give the medicine as ordered by the doctor. Diltiazem can be given in a tablet or ...
... Diltiazem helps to reduce blood pressure by relaxing and widening blood vessels. It also helps the heart to pump more effectively. It is also sometimes used it to increase cyclosporin levels. HOW TO TAKE THIS MEDICINE Give the medicine as ordered by the doctor. Diltiazem can be given in a tablet or ...
Cats with Runny Eyes. Treatment of Feline Herpes Virus Infections
... Famciclovir, a prodrug of penciclovir, is a very safe and effective oral drug for the treatment of FeHV-1 (16-22). Due to complex pharmacokinetics of famciclovir and penciclovir in cats, and the variable target penciclovir concentrations needed to produce a clinical effect, the accurate oral dose is ...
... Famciclovir, a prodrug of penciclovir, is a very safe and effective oral drug for the treatment of FeHV-1 (16-22). Due to complex pharmacokinetics of famciclovir and penciclovir in cats, and the variable target penciclovir concentrations needed to produce a clinical effect, the accurate oral dose is ...
Bilastine
Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.