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antidepressant drug overdoses
antidepressant drug overdoses

... 2,200 calls concerning accidental ingestion of antidepressant medications by pets. Most cases involved dogs, but cats, birds, and potbellied pigs were also exposed. Antidepressants are divided into groups depending on their effects on the central nervous system (CNS) neurotransmitters dopamine, epin ...
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Pharmacokinetic profile and safety of 150 mg of

... associated with an increased risk for postural hypotension. Furthermore, due to sparse pharmacokinetic sampling, this may be an under-representation of the true peak concentrations, as sampling near the time of maximal exposure may have been missed in many subjects. However, we did not observe any p ...
Guidelines for Opioids EN
Guidelines for Opioids EN

... Guidelines for the Conversion from p.o. to Transdermal Route and from Transdermal Route to p.o.  From 12 hours sustained release p.o. to Transdermal:  Apply the patch and give last p.o. dose  From Transdermal to 12 hours sustained p.o.:  Remove the patch and give the first p.o. dose after 8 hour ...
Annex 4 EPI Forms v4
Annex 4 EPI Forms v4

... Cured: An MDR TB patient who has completed the treatment according to programme protocol and has at least five consecutive negative cultures from samples collected at least 30 days apart. If only one positive culture is reported during that time, and there is no concomitant clinical evidence of dete ...
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sult4a1-1 positive - PGXL Laboratories

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Long-term Anticonvulsant Therapy in the Canine Idiopathic Epileptic
Long-term Anticonvulsant Therapy in the Canine Idiopathic Epileptic

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ß-endorphins as Possible Markers for Therapeutic Drug Monitoring
ß-endorphins as Possible Markers for Therapeutic Drug Monitoring

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... Silymarin is able to neutralise the hepatotoxicity of several agents, including Amanita phalloides, ethanol, paracetamol (acetaminophen) and carbon tetrachloride in animal models. The protection against A phalloides is inversely proportional to the time that has elapsed since administration of the t ...
Rapid tranquillisation - The British Journal of Psychiatry
Rapid tranquillisation - The British Journal of Psychiatry

... administered an intramuscular antipsychotic. These reactions can be severe, and extremely unpleasant; they may exacerbate disturbed behaviour (Royal College of Psychiatrists Psychopharmacology Subgroup, 1997) and in newly diagnosed cases of schizophrenia may have long-term consequences due to lack o ...
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Product Information: Dolutegravir (as sodium)

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Lipodystrophy in Patients with Acromegaly Receiving Pegvisomant
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... after initiating pegvisomant therapy. A total of 60 patients have received pegvisomant therapy in our centers. Patient 1 developed extensive, firm anterior abdominal wall swelling that interfered with her ability to dress with her jeans. She had also injected pegvisomant into her thighs and buttocks ...
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... products to replace eye drops and provide sustained therapy for major eye diseases, including glaucoma, dry eye, and allergy. The phase 1b data were collected from a multicenter, prospective, single-arm, open-label, pooled analysis of the bimatoprost ocular insert. In an analysis of 27 subjects, the ...
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... suggested that ACE inhibitors—perindopril specifically—can improve clinical outcome beyond the context of an acute myocardial infarction, as patients in the EUROPA trial were considered to be ‘stable’ and ‘low risk’. Although the benefits of perindopril were apparently due to blood pressure lowering ...
Drug Therapy of Urinary Tract Infections
Drug Therapy of Urinary Tract Infections

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Joint National Committee VII and European Society of Hypertension
Joint National Committee VII and European Society of Hypertension

... physician, yet this assessment may be necessary to take the most appropriate decision about a patient’s treatment. For example, only if patients are at high total cardiovascular risk should effective treatment be instituted quickly and drugs given at lower BP thresholds with the goal of achieving lo ...
guidelines for the use of atypical antipsychotics
guidelines for the use of atypical antipsychotics

... 1) Antipsychotic monotherapy is the recognized standard for the treatment schizophrenia; pharmacological justification for polypharmacy is weak. Combining medications adds to cost of treatment, increases potential for adverse effects, may make adherence more challenging, and increases possibility of ...
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Bilastine



Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
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