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Methylphenidate - Hawkes Bay District Health Board
Methylphenidate - Hawkes Bay District Health Board

... Methylphenidate works best in ADHD patients as part of an overall treatment plan which includes psychological, social and educational measures. Methylphenidate increases the amount of a natural chemical in the brain, called dopamine. Dopamine is responsible for self-control and attention span in the ...
Drugs for Coagulation disorders - Suny-perfusion
Drugs for Coagulation disorders - Suny-perfusion

... • LMW heparins are ONLY administered SC, have a rapid onset of action, generally peak within 3-6 hours, and have a duration of 12-24 hours depending on the agent. Specific LMW heparins include: ...
ULTRAM C IV (tramadol hydrochloride)
ULTRAM C IV (tramadol hydrochloride)

... Not applicable d Not measured ...
Comparative study on the efficacy of - MiVEGEC
Comparative study on the efficacy of - MiVEGEC

... were used simultaneously in the same climatic chamber, one serving as the control. Each net sample was used no more than once, within the same week and then was discarded. ...
MM DD YY 0636 Drugs requiring detailed coding J0585 XXX
MM DD YY 0636 Drugs requiring detailed coding J0585 XXX

... produce symptoms consistent with botulinum toxin effects. These may include asthenia, generalized muscle weakness, diplopia, ptosis, dysphagia, dysphonia, dysarthria, urinary incontinence, and breathing difficulties. These symptoms have been reported hours to weeks after injection. Swallowing and br ...
New therapeutic agents marketed in 2014: Part 3 - learn
New therapeutic agents marketed in 2014: Part 3 - learn

... exists for alteration of the absorption and activity of concomitantly administered oral medications. Although clinically important changes of this type were not identified in several studies, caution should be exercised when oral medications are used concurrently, particularly if their absorption is ...
(Pennsaid) in the management - Brunel University Research Archive
(Pennsaid) in the management - Brunel University Research Archive

... joint [1, 2, 3]. It is postulated that OA will become a global cause of disability by the year 2020 [4] OA is a disorder of middle aged people, predominantly women and is a disease that progresses with advancing age [2,5,6]. Although it is common for radiographic evidence of OA to be present in indi ...
KPGA Formulary Update August 2012
KPGA Formulary Update August 2012

... the electrical activity of the heart (QT interval prolongation), which could pre-dispose patients to develop an abnormal and potentially fatal heart rhythm known as Torsades de Pointes.” ...
JAMA - Medscape
JAMA - Medscape

... second drug from one of the classes in recommendation 6 (thiazide-type diuretic, CCB, ACEI, or ARB). The clinician should continue to assess BP and adjust the treatment regimen until goal BP is reached. If goal BP cannot be reached with 2 drugs, add and titrate a third drug from the list provided. D ...
February-March 2015 - Medical Arts Pharmacy
February-March 2015 - Medical Arts Pharmacy

... duration possible and at failure when compared with the general population. Elderly patients are the lowest effective dose. also more likely to be taking more medications than a healthy adult and are more likely to be at risk from drug interactions with NSAIDs. Elderly individuals are generally at a ...
Glossary - CHRISTUS Health
Glossary - CHRISTUS Health

... manager, research nurse or protocol nurse. Clinical Research - Study of drug, biologic or device in human subjects with the intent to discover potential beneficial effects and/or determine its safety and efficacy. Also called clinical study and clinical investigation. Note that in this manual, this ...
dose-effect relationship
dose-effect relationship

... ④Side effects vary with different therapeutic goals. For example, atropine is used as an antisecretory agent to block secretions in the upper and lower respiratory tracts prior to surgery . ⑤Usually drug in combination is the best way to prevent from side effects. ...
two new third-generation antiepileptic drugs
two new third-generation antiepileptic drugs

... [3,19]. Breveracetam’s renal clearance is low (0,06 mL/min/ kg) and it is eliminated by hepatic metabolism. The major metabolic pathways of BRI include hydrolysis of the acetamide groups and CYP2C8 (microsomal liver cytochrome) – mediated hydroxylation [3,4]. The briveracetam’s half-life elimination ...
February 2008, Number 2
February 2008, Number 2

... regulation. The lack of administration guidelines has the potential to cause patient harm. Examples of harm include additive respiratory depression, excessive daily doses of acetaminophen resulting in liver toxicity, and additive hypotensive effects from antihypertensive medications. A policy has be ...
HIGHLIGHTS OF PRESCRIBING INFORMATION ------------------------ WARNINGS and PRECAUTIONS ------------------------
HIGHLIGHTS OF PRESCRIBING INFORMATION ------------------------ WARNINGS and PRECAUTIONS ------------------------

... fluid retention be minimized. The recommended starting dose of COREG is 3.125 mg twice daily for 2 weeks. If tolerated, patients may have their dose increased to 6.25, 12.5, and 25 mg twice daily over successive intervals of at least 2 weeks. Patients should be maintained on lower doses if higher do ...
Coreg - GSK Source
Coreg - GSK Source

... be minimized. The recommended starting dose of COREG is 3.125 mg twice daily for 2 weeks. If tolerated, patients may have their dose increased to 6.25, 12.5, and 25 mg twice daily over successive intervals of at least 2 weeks. Patients should be maintained on lower doses if higher doses are not tole ...
Irritable bowel syndrome: symptomatic treatment versus integrative
Irritable bowel syndrome: symptomatic treatment versus integrative

... intestines which, in turn, reduce visceral hypersensitivity (Camilleri, 2001). There have been three main randomized, double-blind, placebo-controlled trials in which the use of Tegaserod was compared with placebo in patients suffering from IBS-C (Müller-Lissner, Fumagalli, Bardhan, Pace, Pecher, Na ...
Uniseed Overview and Investments November 2014 1
Uniseed Overview and Investments November 2014 1

... – Betahistine has a long history of safe use in adults – It is proposed to complete preclinical studies and progress the drug into human clinical trials in OME. – Formulation development of a nasal spray completed – Phase 1a trial completed; Phase 1b trial to start ...
NEUROPHARMACOLOGY
NEUROPHARMACOLOGY

... b) Cross-dependence: refers to the ability of a drug to prevent withdrawal symptoms arising from chronic use of another drug. e.g. codeine was often used for this purpose in the past by heroin users when heroin was not available c) Psychological dependence: book uses “Psychic dependence”; strong des ...
FDA-Approved Treatments for Alzheimer`s
FDA-Approved Treatments for Alzheimer`s

... — are from a class of drugs called “cholinesterase inhibitors.” These drugs prevent the breakdown of a chemical messenger in the brain that is important for learning and memory. The fourth drug, memantine, regulates the activity of a different chemical messenger in the brain that is also important f ...
5 points
5 points

... Design a dosing regimen (dose and dosing interval) for gentamicin to achieve steady state peak and trough concentrations of 20 mg/L and 6 mg/L, respectively, assuming a short-term infusion of 2 hour infusion duration. The approximation for gentamicin volume of distribution is 0.25 L/kg. The patient ...
IV-phenytoin-in-SE-version 3.1 final
IV-phenytoin-in-SE-version 3.1 final

... 3. What dose of phenytoin should be used? The BNF3 recommends for adults a dose of 20 mg/kg (maximum 2 grams) by slow intravenous injection or infusion (with blood pressure and ECG monitoring), 20 mg/kg (max. 2 g) at a rate not exceeding 1 mg/kg/minute (max. 50 mg per minute), as a loading dose. As ...
Diapositivo 1
Diapositivo 1

... After repeated opioid exposure: • The neuron increases its supply of enzymes and ATP molecules. • It produces enough cAMP to offset the inhibitory effect of the drug. ...
Adrenergic Receptor Agonists
Adrenergic Receptor Agonists

... effects. Indirect acting agonists work at the nerve terminal to promote the release and/or block the reuptake of endogenous neurotransmitters. These agents have little activity if these neurotransmitters are depleted. Cocaine and amphetamine interact with cell surface monoamine transporters for dopa ...
Ibogaine
Ibogaine

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Bilastine



Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
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