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Boletín Latinoamericano y del Caribe de Plantas Medicinales y
Boletín Latinoamericano y del Caribe de Plantas Medicinales y

... of the region, related to the central subject of the Bulletin ...
Intravenous Anesthesia 1991
Intravenous Anesthesia 1991

... hypotension. Patients in hypovolemic shock should not be induced with propofol. Premedication with opioids decreases the propofol dose necessary for induction of anesthesia, decreases the hemodynamic response to noxious stimuli such as laryngoscopy and intubation, and increases the likelihood of hyp ...
field and action potential recordings in heart slices
field and action potential recordings in heart slices

... sensitive, predictive, and informative, they usually suffer from a low throughput. One promising approach to overcome this limitation constitutes the synchronous recording of bioelectrical signals from multiple cardiac tissue slices, a technique which has been recently optimised (Bussek et al., 2009 ...
Comparison of Anti-Xa and Dilute Russell Viper Venom Time
Comparison of Anti-Xa and Dilute Russell Viper Venom Time

... method for determining rivaroxaban levels (Figure 2, C). COMMENT Although routine laboratory monitoring is not required when patients are administered rivaroxaban, there are several clinical situations where determination of the level of anticoagulation is of value. There have been recent reports ev ...
AusPAR Nivolumab  - Therapeutic Goods Administration
AusPAR Nivolumab - Therapeutic Goods Administration

... depending on: (a) BRAF V600 tumour status, and (b) the patient’s clinical stability. The NCCN did recommend nivolumab (among other options) as first line therapy in all settings, but did not endorse nivolumab + ipilimumab combination therapy. It may be argued disease control by BRAF inhibitors is tr ...
Position Paper: Ipecac Syrup
Position Paper: Ipecac Syrup

... minutes. These results are difficult to interpret because of the small number of volunteers who ingested only 12 dosage forms of the study drugs. There were very large ranges for AUC values (4 – 110% and 26 –150% for acetaminophen, 0– 89% and 38– 149% for tetracycline, and 0 –95% and 7 –155% for ami ...
Clinical and pharmacological evaluation of buprenorphine and
Clinical and pharmacological evaluation of buprenorphine and

... suppress withdrawal in highly dependent subjects. More recent substitution and challenge studies of partial agonists of morphine were conducted with volunteers dependent on 60 mg morphine sulfate given in four daily 15 mg s.c. or i.m. doses. At this dose, sufficient effects were produced to reliably ...
Diagnosis, Prevention and Management of Statin Adverse Effects
Diagnosis, Prevention and Management of Statin Adverse Effects

... • Offending statin can be documented to be ineffective at achieving goal (note: this does not exclude trial of this particular statin in the future or use of this agent at lower doses as chronic therapy). • Symptoms have not resolved or increase after a reasonable drug holiday raising the possibilit ...
MDMA powder
MDMA powder

... pain relief and improved quality of life.[15] In the United States, no research on MDMA was allowed at all, from 1985 until 1992, when the FDA approved Dr. Charles Grob to conduct human studies.[16] In the year 2000, Doctor Jose Carlos Bouso performed the first clinical trial of MDMA for use in trea ...
PDF
PDF

... frequent feature in alcoholics and addicted patients during acute and chronic withdrawal (Heinz et al., 1994), as well as in cocaine, stimulant, and cannabis abusers (Gawin et al., 1988; Miller et al., 1993; Bovasso, 2001). In a study performed by Heinz et al. (1994), it was found that anhedonia, dy ...
Special Contribution Acetaminophen-Induced Hepatotoxicity: Still an
Special Contribution Acetaminophen-Induced Hepatotoxicity: Still an

... the GSH/oxidized glutathione (GSSG) ratio (Jaeschke, 1990; Lores Arnaiz et al., 1995; Amimoto et al., 1995) in animal livers. These endogenous antioxidants, especially α-Toc, CoQ 9 H 2 and CoQ10H2 scavenge lipid peroxyl radicals and consequently their own levels decrease (Matsura et al., 1992a, 1992 ...
Restless Legs Syndrome
Restless Legs Syndrome

... several years. People with early symptoms are more likely to have other family members with RLS than people who develop RLS later in life. Symptoms tend to worsen faster when RLS occurs later in life. RLS that occurs later in life is also more likely to result from an underlying condition or illness ...
Opinion of the Scientific Panel on Dietetic Products, Nutrition and
Opinion of the Scientific Panel on Dietetic Products, Nutrition and

... regard to total phytosterols, now >97%, major phytosterols, now >88% and sitostanol, now 1534%. In addition, Reducol™ obtained by the new process was found to have a lower average content of minor sterols including stigmasterol, 7.0% (3.4-9.8%) compared with 9.3% (4.614.7%) for Reducol™ obtained by ...
BOTULINUM TOXINS A AND B
BOTULINUM TOXINS A AND B

... They are not interchangeable and, therefore, the units of biological activity cannot be compared to nor converted into units of any other botulinum toxin products assessed with any other specific Botulinum Toxins A and B: Drug Policy (Effective 02/01/2014) ...
Antiemesis - proLekare.cz
Antiemesis - proLekare.cz

... Any clinician seeking to apply or consult the NCCN Guidelines is expected to use independent medical judgment in the context of individual clinical circumstances to determine any patient’s care or treatment. The National Comprehensive Cancer Network® (NCCN®) makes no representations or warranties of ...
Osteomyelitis: an overview of antimicrobial therapy Diana Gomes , Margarida Pereira
Osteomyelitis: an overview of antimicrobial therapy Diana Gomes , Margarida Pereira

... most common causative organism responsible for more than 50% of osteomyelitis cases. Osteomyelitis treatment implies the administration of high doses of antibiotics (AB) by means of endovenous and oral routes and should take a period of at least 6 weeks. Local drug delivery systems, using non-biodeg ...
Milk Thistle and Its Derivative Compounds: A Review of
Milk Thistle and Its Derivative Compounds: A Review of

Pain Management: Trigeminal Neuralgia
Pain Management: Trigeminal Neuralgia

... trigeminal neuralgia; however none of the theories explain the process completely. Theories regarding pathogenesis may ultimately be classified as either central or peripheral.3 Central theories are based on the similarity of trigeminal neuralgia to focal epilepsy and emphasize the role of deafferen ...
Effects of D-002 (Beeswax Alcohols) on Concentrations of
Effects of D-002 (Beeswax Alcohols) on Concentrations of

... induced gastric ulcer in rats. Methods and Findings: Rats were randomized into six groups: a negative control that only received the vehicle and five groups with ethanol induced gastric ulcer: a positive control (vehicle-treated), three treated with D-002 (25, 100 and 200 mg/kg) and one with omepraz ...
Everolimus Novartis tablet ENG SmPC
Everolimus Novartis tablet ENG SmPC

... Hepatic transplant patients should have their tacrolimus exposure reduced to minimise calcineurinrelated renal toxicity. The tacrolimus dose should be reduced starting approximately 3 weeks after initiating co-administration with Everolimus Novartis, based on targeted tacrolimus blood trough concent ...
04_Intravenous infusion
04_Intravenous infusion

... concentration of a drug with one compartment PK resulting from the administration of an IV infusion (K0= Css∙Cl ) and a loading bolus (LD= Css∙Vd) that was given at the start of the infusion ...
Print - Arteriosclerosis, Thrombosis, and Vascular Biology
Print - Arteriosclerosis, Thrombosis, and Vascular Biology

... level fell by 77% and their cholesterol level by 41%. The fall in very low density lipoprotein (VLDL) cholesterol level was reciprocated by increments in the cholesterol level in both LDL and high density lipoproteins (HDL); the rise in HDL was confined to HDL3. LDL catabolism was examined before an ...
one  that I'm not aware
one that I'm not aware

... OTC products ...
PrCIPRO® XL - Bayer Canada
PrCIPRO® XL - Bayer Canada

... Crystalluria related to ciprofloxacin has been reported only rarely in man because human urine is usually acidic. Crystals have been observed in the urine of laboratory animals, usually from alkaline urine. Patients receiving ciprofloxacin should be well hydrated and alkalinity of the urine should b ...
PrCIPRO® XL
PrCIPRO® XL

... Crystalluria related to ciprofloxacin has been reported only rarely in man because human urine is usually acidic. Crystals have been observed in the urine of laboratory animals, usually from alkaline urine. Patients receiving ciprofloxacin should be well hydrated and alkalinity of the urine should b ...
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Bilastine



Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
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