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Quest For Quality
Quest For Quality

... Chronic pain: How has pain changed the patient’s life? What could you do before that pain keeps you from doing now? c) End of life: Is there anything you want to accomplish before death that pain would keep you from doing? F. Adjust treatment plan based on response: Level of function/QOL, pain relie ...
Sirolimus fact sheet
Sirolimus fact sheet

... The Elecsys Sirolimus assay is used as an aid in the management of kidney transplant patients receiving sirolimus therapy. Organ transplant patients are prescribed with immunosuppressant drugs (ISD) like e.g. sirolimus so that the immune system does not reject the newly transplanted organ. ISD assay ...
Treatment Options for Acute Migraine
Treatment Options for Acute Migraine

... Treatment Options for Acute Migraine serotonin antagonist pizotifen or a calcium channel blocker (usually verapamil or flunarizine) are used as first-line preventive therapies, even though their clinical profiles are suboptimal. These drugs may be best used as second-line therapies, unless coindicat ...
IRB Terms Glossary
IRB Terms Glossary

... Confounding Factor: Any factor that might serve as an alternative explanation for a study’s result; confounding factors include non-randomized samples, selection bias, and any arbitrary differences between people that are being compared. Contraindicated: Disadvantageous, perhaps dangerous; a treatme ...
Peridex and PerioMed Oral Rinse Brochure
Peridex and PerioMed Oral Rinse Brochure

... inflammation following treatment with Peridex oral rinse should not be used as a major indicator of underlying periodontitis. 2. Peridex oral rinse can cause staining of oral surfaces, such as tooth surfaces, restorations, and the dorsum of the tongue. Not all patients will experience a visu ...
Product Monograph - Ask Novartis Pharma
Product Monograph - Ask Novartis Pharma

... Any chloride deficit during thiazide therapy is generally mild and usually does not require specific treatment except under extraordinary circumstances (as in liver disease or renal disease). Dilutional hyponatremia may occur in edematous patients in hot weather; appropriate therapy is water restric ...
platelet function testing-guided antiplatelet therapy
platelet function testing-guided antiplatelet therapy

... was used in GRAVITAS to identify clopidogrel low-responders defined a high proportion of patients with HPR who did not exhibit any greater thrombotic risk compared to the control cohort of clopidogrel normal responders in the observational substudy. According to a post hoc analysis of the GRAVITAS re ...
Subsys Prescribing Information
Subsys Prescribing Information

...  Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals (2.1)  Individualize dosing based on the severity of pain, patient response, prior analgesic experience, and risk factors for addiction, abuse, and misuse. ...
update on antiplatelet therapy in the treatment and prevention
update on antiplatelet therapy in the treatment and prevention

... Voluntary Professor of Family Medicine and Community Health University of Miami Miller School of Medicine ...
Hydrocodone Bitartrate
Hydrocodone Bitartrate

... antitussive, hydrocodone is prescribed for a limited duration to manage cough and upper respiratory symptoms associated with the common cold or allergies in adults and pediatric patients 6 years of age and older. In isolated cases, hydrocodone may be prescribed for an extended time period in those ...
The prokinetic cinitapride has no clinically relevant pharmacokinetic
The prokinetic cinitapride has no clinically relevant pharmacokinetic

... maximum daily doses for ketoconazole, the higher single dose posology is not used clinically and has been shown to have itself a significant effect on the QTc interval (Chaikin et al., 2005) that would confound the object of the study. In any event, the dose of 200 mg even once daily has been used f ...
Effects of ()-HA-966, CGS-19755, Phencyclidine, and Dizocilpine on
Effects of ()-HA-966, CGS-19755, Phencyclidine, and Dizocilpine on

... the repeated acquisition procedure after 6 to 8 months of training. Values of baseline percent errors and response rates were very similar across animals. In baseline sessions, most errors were made as the first few reinforcers were earned (i.e., reinforcers 1–3, or 5–15 correct sequences). Comparis ...
Substitution treatment Methadone 2 stage Engl
Substitution treatment Methadone 2 stage Engl

... 3.5. The objectives of the treatment From a physician point of view, the most important objective is to "maintain contact with the system of assistance ", followed by "the improvement of the self-image ". The objective of abstinence is of little importance for the physicians working in Brussels’s i ...
CDR Pharmacoeconomic Review Report for Botox (Migraine)
CDR Pharmacoeconomic Review Report for Botox (Migraine)

... different in other jurisdictions and, if used outside of Canada, it is at the user’s risk. This disclaimer and any questions or matters of any nature arising from or relating to the content or use (or misuse) of this document will be governed by and interpreted in accordance with the laws of the Pro ...
United Kingdom Veterinary Medicines Directorate Woodham Lane
United Kingdom Veterinary Medicines Directorate Woodham Lane

... No teratogenicity, foetotoxicity or toxic effects on fertility, gestation, viability or lactation were found in rats when treated at up to 90 mg/kg/day from day 14 prior to mating. No adverse effects on foetuses occurred in rabbits dosed from day 7 – 17 of gestation with up to 90 mg/kg/day but an in ...
Neonatal Abstinence Syndrome Case Study
Neonatal Abstinence Syndrome Case Study

... delivery, technical issues around collecting urine from the baby may influence results. Those include the challenges of obtaining a urine from the standard urine collection bag, the type of screen done by the lab at UNM versus Tricore labs, and the degree of urine concentration by the baby. The tech ...
Menopause 4-5-11 - UNC School of Medicine
Menopause 4-5-11 - UNC School of Medicine

QA168_7Renal replacement therapiesOct15 final
QA168_7Renal replacement therapiesOct15 final

... soluble metabolites, which are then renally excreted. These may be removed by RRT, but often data are lacking on the amounts removed and the toxicity of the metabolites (8,9). Non-renal clearance – The pharmacokinetics of some drugs which undergo hepatic clearance via CYP3A4 and via drug transporter ...
SPHAERANTHUS INDICUS INDUCED DIABETIC RATS Research Article
SPHAERANTHUS INDICUS INDUCED DIABETIC RATS Research Article

... The comparable effect of the S. indicus extract with glibenclamide (Figure 1) may suggest similar mode of action, since alloxan permanently destroys the pancreatic -cells and the extracts lowered blood glucose level in alloxan induced rats to significant level. This indicates that the extracts poss ...
alcoholism pharmacotherapy
alcoholism pharmacotherapy

... Naltrexone, an opioid antagonist, was originally developed for use in the prevention of relapse in detoxified opiate addicts. Naltrexone has a half-life of approximately 4 hours, and 6-�-naltrexol, its major metabolite, has a half-life of 12 hours. Rapidly absorbed, naltrexone reaches peak plasma le ...
Editorial Response: Single Daily Dosing of Aminoglycosides
Editorial Response: Single Daily Dosing of Aminoglycosides

... time required for resolution of the surrogate markers of infection. These investigators dosed aminoglycosides with use of individualized pharmacokinetic monitoring on an 8-hour, 12hour, or 24-hour schedule, depending on renal function, to optimize the postdistributional Cmax/MIC ratio and limit rena ...
Effects of amiodarone on thyroid function
Effects of amiodarone on thyroid function

... Dronedarone was approved by the FDA in 2009 for the treatment of atrial fibrillation (1). This drug has similar electrophysiologic properties to those of amiodarone (10), but does not contain iodine. The DIONYSOS study demonstrated that there was significantly lower incidence of thyroid dysfunction ...
ARIA Oncology Information System
ARIA Oncology Information System

... When the patient arrives for radiation treatment, his approved plan is simply loaded from the Varian system database. All reference images, treatment fields, MLC and related console parameters are available for the therapist. After treatment, radiation dose is immediately recorded. For chemotherapy ...
Design and evaluation of edible gels of alendronate ISSN:2320-2831
Design and evaluation of edible gels of alendronate ISSN:2320-2831

... The main mechanism for the absorption of the drug into oral mucosa is via passive diffusion into the lipoidal membrane 3. The absorption of the drug through the sublingual route is 3 to 10 times greater than oral route and is only surpassed by hypodermic injection. For these formulations, the small ...
CIPROXIN Tablets PI
CIPROXIN Tablets PI

... Maximum serum concentrations are attained 1 to 2 hours after oral dosing. Mean concentrations 12 hours after dosing with 250, 500 or 750 mg are 0.1, 0.2 and 0.4 µg/mL respectively. Metabolism Ciprofloxacin is also metabolised. Four metabolites have been identified in human urine which together accou ...
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Bilastine



Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.
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