Committee on Drugs 1997;99;918 DOI: 10.1542/peds.99.6.918
... circulation of these drugs is noted in adults, which affects drug response, especially with repeated dosing.3 The relative immaturity of hepatic enzyme systems that metabolize drugs in young children may enhance the risk of adverse effects of such medications, especially in infants younger than 6 mo ...
... circulation of these drugs is noted in adults, which affects drug response, especially with repeated dosing.3 The relative immaturity of hepatic enzyme systems that metabolize drugs in young children may enhance the risk of adverse effects of such medications, especially in infants younger than 6 mo ...
Relative Reinforcing Effects of Cocaine, Remifentanil, and Their
... returned to 10, and saline replaced the drug solution for at least one session. When the number of saline infusions decreased to less than 30 in a single session, the drug solution was again made available on fixed ratio 10, and the ratio series was repeated. Each dose of both drugs was made availab ...
... returned to 10, and saline replaced the drug solution for at least one session. When the number of saline infusions decreased to less than 30 in a single session, the drug solution was again made available on fixed ratio 10, and the ratio series was repeated. Each dose of both drugs was made availab ...
Do Children Receive Appropriate Treatment for
... One mother also had this to say: The use of ampicillin is good in curing wounds. When I mix this with palm kennel oil, it becomes very potent to heal all wounds within less than a week. Another mother mentioned an instance where she used gentian violet solution to treat a minor burn case at home bec ...
... One mother also had this to say: The use of ampicillin is good in curing wounds. When I mix this with palm kennel oil, it becomes very potent to heal all wounds within less than a week. Another mother mentioned an instance where she used gentian violet solution to treat a minor burn case at home bec ...
Effects of risperidone, amisulpride and nicotine on eye
... Clementz et al. 1995; Lencz et al. 1993), and in psychometric schizotypy (Ettinger et al. 2005; Gooding 1999; Holahan and O’Driscoll 2005; O’Driscoll et al. 1998). Second, several studies have investigated the effects of psychotropic drugs on oculomotor control in healthy volunteers and schizophreni ...
... Clementz et al. 1995; Lencz et al. 1993), and in psychometric schizotypy (Ettinger et al. 2005; Gooding 1999; Holahan and O’Driscoll 2005; O’Driscoll et al. 1998). Second, several studies have investigated the effects of psychotropic drugs on oculomotor control in healthy volunteers and schizophreni ...
Local Anesthesia in Dentistry
... supports the use of articaine in children under 4 years of age. However, anecdotal information and a report by Brickhouse et al in 200822, suggests that a quarter of dentists surveyed (n=373) used articaine regularly in children aged 2-3 years of age with no problems. Lidocaine’s prescribing informa ...
... supports the use of articaine in children under 4 years of age. However, anecdotal information and a report by Brickhouse et al in 200822, suggests that a quarter of dentists surveyed (n=373) used articaine regularly in children aged 2-3 years of age with no problems. Lidocaine’s prescribing informa ...
Prescribing Information Only Fluticasone Propionate Nasal Spray
... or perennial allergic rhinitis. The trials included 2,633 adults (1,439 men and 1,194 women) with a mean age of 37 (range, 18 to 79 years). A total of 440 adolescents (405 boys and 35 girls), mean age of 14 (range, 12 to 17 years), and 500 children (325 boys and 175 girls), mean age of 9 (range, 4 t ...
... or perennial allergic rhinitis. The trials included 2,633 adults (1,439 men and 1,194 women) with a mean age of 37 (range, 18 to 79 years). A total of 440 adolescents (405 boys and 35 girls), mean age of 14 (range, 12 to 17 years), and 500 children (325 boys and 175 girls), mean age of 9 (range, 4 t ...
Updating the Beers Criteria for Potentially Inappropriate Medication
... medication use in older adults are the Beers criteria and the Canadian criteria.12-14 The Beers criteria are based on expert consensus developed through an extensive literature review with a bibliography and questionnaire evaluated by nationally recognized experts in geriatric care, clinical pharmac ...
... medication use in older adults are the Beers criteria and the Canadian criteria.12-14 The Beers criteria are based on expert consensus developed through an extensive literature review with a bibliography and questionnaire evaluated by nationally recognized experts in geriatric care, clinical pharmac ...
Relationship between availability of emergency department
... remaining errors were either categorized as having no or minor impact on health outcome. The authors concluded that pre-admission medication reconciliation performed by ED-based pharmacists reduces commission and omission medication errors significantly in elderly patients with more than four routin ...
... remaining errors were either categorized as having no or minor impact on health outcome. The authors concluded that pre-admission medication reconciliation performed by ED-based pharmacists reduces commission and omission medication errors significantly in elderly patients with more than four routin ...
Medications in Pregnancy and Lactation
... human teratogenic effects (Category X). This second installment concentrates on drugs with minimal or unknown human teratogenic effects. Table 2 lists some of the most common medications (in alphabetical order) with minimal or unknown human teratogenic effects. Categories A and B generally are consi ...
... human teratogenic effects (Category X). This second installment concentrates on drugs with minimal or unknown human teratogenic effects. Table 2 lists some of the most common medications (in alphabetical order) with minimal or unknown human teratogenic effects. Categories A and B generally are consi ...
ESMOLOL VERSUS DEXMEDETOMIDINE IN SCOLIOSIS SURGERY: STUDY ON INTRAOPERATIVE BLOOD LOSS
... study was to compare the effects of esmolol or dexmedetomidine on intraoperative blood loss, anesthetics consumption, intra operative hemodynamic and effects on spinal cord monitoring in patients undergoing scoliosis surgery. Methods: After obtaining institute review board approval and written infor ...
... study was to compare the effects of esmolol or dexmedetomidine on intraoperative blood loss, anesthetics consumption, intra operative hemodynamic and effects on spinal cord monitoring in patients undergoing scoliosis surgery. Methods: After obtaining institute review board approval and written infor ...
D-Cycloserine in Neuropsychiatric Diseases: A
... DCS has been used for over one-half a century in tuberculosis therapy, the doses used for this indication being clearly up to about 20 times higher than for modulation of neuroplasticity. The pharmacological properties and side effects are well known and have been described elsewhere (Goodman et al ...
... DCS has been used for over one-half a century in tuberculosis therapy, the doses used for this indication being clearly up to about 20 times higher than for modulation of neuroplasticity. The pharmacological properties and side effects are well known and have been described elsewhere (Goodman et al ...
HIGHLIGHTS OF PRESCRIBING INFORMATION ------------------------------CONTRAINDICATIONS-------------------------------
... Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogues alone or in combination, including didanosine and other antiretrovirals. A majority of these cases have been in women. Obesity and prolonged nucleoside exposure may ...
... Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogues alone or in combination, including didanosine and other antiretrovirals. A majority of these cases have been in women. Obesity and prolonged nucleoside exposure may ...
Issues around the Prescription of Half Tablets in Northern
... advantage is further a favourable profile of acute extrapyramidal side effects that occur in very rare cases [15]. Offlabel use, that is, unlabeled or unapproved use, is common in conditions such as agitation, anxiety, dementia, obsessivecompulsive disorders, psychosis [16], and delirium [17, 18]. B ...
... advantage is further a favourable profile of acute extrapyramidal side effects that occur in very rare cases [15]. Offlabel use, that is, unlabeled or unapproved use, is common in conditions such as agitation, anxiety, dementia, obsessivecompulsive disorders, psychosis [16], and delirium [17, 18]. B ...
VRX-03011, a novel 5-HT4 agonist, enhances memory and
... performance while none of the doses enhanced performance in the no-delay test. VRX-03011 (1 and 5 mg/kg) concomitantly enhanced hippocampal acetylcholine output and delayed spontaneous alternation scores compared to that of vehicle controls, but had no effect on hippocampal acetylcholine release und ...
... performance while none of the doses enhanced performance in the no-delay test. VRX-03011 (1 and 5 mg/kg) concomitantly enhanced hippocampal acetylcholine output and delayed spontaneous alternation scores compared to that of vehicle controls, but had no effect on hippocampal acetylcholine release und ...
Reporting Bias in Clinical Trials Investigating the Efficacy of Second
... results the FDA used to decide whether the trial was positive (ie, whether it could be used to support marketing approval). Data were extracted preferably from the statistical review but also from the medical review and administrative correspondence (eg, memos by team leaders). In cases in which mul ...
... results the FDA used to decide whether the trial was positive (ie, whether it could be used to support marketing approval). Data were extracted preferably from the statistical review but also from the medical review and administrative correspondence (eg, memos by team leaders). In cases in which mul ...
1 Phenol Synonym: carbolic acid CAS: 108-95
... Phenol is considered to be very toxic to humans through oral exposure, with symptoms including muscle weakness and tremors, loss of coordination, paralysis, convulsions, coma, and respiratory arrest. Among systemic symptoms of toxicity, e.g. nausea, diarrhea, hypotension, dysrhythmia, pulmonary edem ...
... Phenol is considered to be very toxic to humans through oral exposure, with symptoms including muscle weakness and tremors, loss of coordination, paralysis, convulsions, coma, and respiratory arrest. Among systemic symptoms of toxicity, e.g. nausea, diarrhea, hypotension, dysrhythmia, pulmonary edem ...
Product Monograph
... has been seen in animal studies. The hematopoietic effects occurred at oral doses of 40 and 80 mg/kg/day in dogs and rats, respectively (at exposures approximately 0.6 times in the dog and equal in the rat to the expected human exposure based on AUC). Hematopoietic effects were reversible, although ...
... has been seen in animal studies. The hematopoietic effects occurred at oral doses of 40 and 80 mg/kg/day in dogs and rats, respectively (at exposures approximately 0.6 times in the dog and equal in the rat to the expected human exposure based on AUC). Hematopoietic effects were reversible, although ...
Determining the subjective and physiological effects
... these studies provide a basis for further investigation into the stimulant-like effects of BZP. To date, there is very little data published about the subjective effects of BZP other than that produced by Campbell and Bye and that reported anecdotally by individuals on drug culture-related websites ...
... these studies provide a basis for further investigation into the stimulant-like effects of BZP. To date, there is very little data published about the subjective effects of BZP other than that produced by Campbell and Bye and that reported anecdotally by individuals on drug culture-related websites ...
Testosterone Cypionate Injection, USP
... Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking. There have been postmarketing reports of venous thromboembolic events, including deep vein thrombosis (DV ...
... Geriatric patients treated with androgens may be at an increased risk of developing prostatic hypertrophy and prostatic carcinoma although conclusive evidence to support this concept is lacking. There have been postmarketing reports of venous thromboembolic events, including deep vein thrombosis (DV ...
Hycodan® (hydrocodone bitartrate) - Bristol
... measures as necessary. The benefit to risk ratio should be carefully considered, especially in children with respiratory embarrassment (e.g. croup). Estimation of dosage relative to the child's age and weight is of great importance. Use in Patients with Chronic Pulmonary Disease: Monitor patients wi ...
... measures as necessary. The benefit to risk ratio should be carefully considered, especially in children with respiratory embarrassment (e.g. croup). Estimation of dosage relative to the child's age and weight is of great importance. Use in Patients with Chronic Pulmonary Disease: Monitor patients wi ...
Mylan`s Authorized Generic to EpiPen® (epinephrine injection, USP
... drugs in terms of dosage, safety, strength, quality, the way they work and the way they are administered. An AG is a brand-name prescription drug – already approved by FDA – and marketed as a generic under a private label. The AG is sold and distributed as a generic product. Unlike a standard generi ...
... drugs in terms of dosage, safety, strength, quality, the way they work and the way they are administered. An AG is a brand-name prescription drug – already approved by FDA – and marketed as a generic under a private label. The AG is sold and distributed as a generic product. Unlike a standard generi ...
Body Temperature and Analgesic Effects of Selective Mu and Kappa
... Accepted for publication December 5, 1996 ...
... Accepted for publication December 5, 1996 ...
Early Diagnosis and Treatment of Discoid Lupus Erythematosus BRIEF REPORT
... available in the United States but is freely available in other countries like the United Kingdom. It is customary to start hydroxychloroquine at a dose of 200 mg per day for an adult and, if there are no untoward gastrointestinal or other side effects, to increase the dose to twice a day. No more t ...
... available in the United States but is freely available in other countries like the United Kingdom. It is customary to start hydroxychloroquine at a dose of 200 mg per day for an adult and, if there are no untoward gastrointestinal or other side effects, to increase the dose to twice a day. No more t ...
A New Therapeutic Option for Metastatic Breast Cancer
... More than a million women are diagnosed with breast cancer annually worldwide. Death from breast cancer is usually a result of chemotherapy‑resistant metastatic disease. Eribulin mesylate is a recent addition to the therapeutic armamentarium for treating locally advanced or metastatic breast cancer ...
... More than a million women are diagnosed with breast cancer annually worldwide. Death from breast cancer is usually a result of chemotherapy‑resistant metastatic disease. Eribulin mesylate is a recent addition to the therapeutic armamentarium for treating locally advanced or metastatic breast cancer ...
Bilastine
Bilastine (trade name Bilaxten) is a second generation antihistamine drug for the treatment of allergic rhinoconjunctivitis and urticaria (hives).It exerts its effect as a selective histamine H1 receptor antagonist, and has a effectiveness similar to cetirizine, fexofenadine and desloratadine. It was developed in Spain by FAES Farma.Bilastine is approved in the European Union for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria, but it is not approved by the U.S. Food and Drug Administration for any use in the United States. Bilastine meets the current European Academy of Allergy and Clinical Immunology (EAACI) and Allergic Rhinitis and its Impact of Asthma (ARIA) criteria for medication used in the treatment of allergic rhinitis.Bilastine has been effective in the treatment of ocular symptoms and diseases of allergies, including rhinoconjuctivitis. Additionally, bilastine has been shown to improve quality of life, and all nasal and ocular symptoms related to allergic rhinitis.