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multiple choice questions (MCQs)
multiple choice questions (MCQs)

...  A 26-year-old woman has been on antidepressant therapy for several months. ...
Psychotropic drug interactions
Psychotropic drug interactions

... such as digoxin, warfarin, sulfonylureas or phenytoin. Most psychotropics are protein-bound to a certain extent with the exception of lithium and gabapentin. Induction increases the metabolism of the substrate drug, causing reduced plasma levels. This is significant for drugs where a reduced plasma ...
The Effects of a Required Autopsy Exercise on Medical
The Effects of a Required Autopsy Exercise on Medical

... Drug interaction is a significant problem in patients who are on multiple medications especially in the geriatric population. We report an interesting case of drug interaction between warfarin and vaginal miconazole preparation, presenting as a small bowel intra-mural haematoma necessitating surgery ...
Principles of Drug Action
Principles of Drug Action

... 95% bound to plasma proteins. Steady state plasma concentration is reached after 7-10 days. The onset of anti-psychotic effect can take several weeks, but maximum effect may require several months. In treatment resistant schizophrenia, patients have been reported to continue to improve for at least ...
Common Drug Interactions Leading to Adverse Drug
Common Drug Interactions Leading to Adverse Drug

... formulated with tartaric acid to create an acidic environment for maximal dipyridamole absorption.5 Extent of Gastrointestinal Drug Metabolism A number of metabolizing enzymes along the small intestinal wall can significantly biotransform many compounds before they are absorbed into the systemic cir ...
Drug Safety Initiative - Psychiatric Medication Awareness Group
Drug Safety Initiative - Psychiatric Medication Awareness Group

... population. For phenytoin, changes in PK activity in metabolism and elimination do not allow the drug to efficiently be removed from the patient. ■ Elimination: Elimination is a major problem in the geriatric patient. Most medications are removed from the body through the kidney. Without the presenc ...
acpnews July/August 2005 - Alberta College of Pharmacists
acpnews July/August 2005 - Alberta College of Pharmacists

... information important to their practices, discussed pharmacy issues with other delegates and speakers, and caught up on news with classmates and colleagues. Much of the feedback particularly mentions the calibre of the speakers and the relevance of the topics. Videos of our award winners were a high ...
DrugRxn2011Im
DrugRxn2011Im

... Cautiously Administer Drug if Use is Essential ...
Formulation Tactics for the Delivery of Poorly Soluble Drugs
Formulation Tactics for the Delivery of Poorly Soluble Drugs

Product Development Issues of Powders for Injection
Product Development Issues of Powders for Injection

... primary pack allows the formulation of drugs that are thermolabile or unstable in aqueous solution. However, lyophilization normally yields an amorphous or partially amorphous product, which leads to solid-state instability (3). A more-stable crystalline stage can be obtained by crystallization in a ...
Presentation
Presentation

... nutrition, concomitant drug use or other strategy…. 2. Choice of drug according to factual criteria: pathophysiology, mechanism of action, the above conditions, characteristics of drug product…. Gunnar Alvan November 2002 ...
(Piportil Depot) Oct 2014
(Piportil Depot) Oct 2014

... but zuclopenthixol may be suitable for the treatment of agitated or aggressive patients whereas flupentixol can cause over-excitement in such patients. Zuclopenthixol decanoate may be more effective in preventing relapses than other conventional antipsychotic depot preparations. The incidence of ext ...
27 October 2014 Dear Colleagues Discontinuation of Piportil
27 October 2014 Dear Colleagues Discontinuation of Piportil

... but zuclopenthixol may be suitable for the treatment of agitated or aggressive patients whereas flupentixol can cause over-excitement in such patients. Zuclopenthixol decanoate may be more effective in preventing relapses than other conventional antipsychotic depot preparations. The incidence of ext ...
Pediatric Dosage Calculation
Pediatric Dosage Calculation

... Read a label • Some dosage questions will require you to read a drug label ...
Metabolizing Enzymes and Transporter Proteins: How
Metabolizing Enzymes and Transporter Proteins: How

Renal Dose Adjustment per Pharmacy
Renal Dose Adjustment per Pharmacy

... for contacting the provider to suggest alternatives. D. If the medication is not on the renal dosing list (see Table 1), the pharmacist is responsible for contacting the prescriber for approval if dosing adjustment is needed. E. If the original ordered dose is not appropriate for the indication, the ...
Routes of drug administration
Routes of drug administration

... (cf. stomach - acidic). Thus a drug may be more stable. Sunday, May 14, 2017 ...
STATUS DECISION OF CONTROLLED AND NON
STATUS DECISION OF CONTROLLED AND NON

... and are not controlled under the CDSA. California Poppy extract is from a plant named Eschscholzia californica Cham.(papveraceae), the extracts of which have been reported to contain various compounds such as alkaloids, amino acids, and tannins. Studies on alcoholic extracts of E. californica Cham. ...
Nanocochleate - a new approach in lipid drug delivery
Nanocochleate - a new approach in lipid drug delivery

... most  non‐hospitalized,  non‐acute  care  patients.  Drug  delivery  systems  that  allow  oral  delivery  improve  patient  compliance  and  facilitate  treatment  outside  the  hospital,  which  has  a  significant  impact  on  healthcare  economics.  Recently,  many  drug  delivery  platforms hav ...
- Premier University of Technology
- Premier University of Technology

... i. Hematological, pathological and biochemical investigations as markers of major organ damage and their effect on drug therapy decisions. 7. Concept of essential drugs and rational drug use. 8. Concept of therapeutic drug monitoring. 9. General principles of clinical toxicology 10. Drug treatment d ...
USA Product Label
USA Product Label

... Panacur® Granules 22.2% did not cause toxicity when administered to weaned pups at doses equal to 5 times the recommended daily dose and for 2 times the duration of treatment. ADVERSE REACTIONS Another benzimidazole has been reported to cause hepatoxicity clinically in canines. However, this effect ...
WAUSAU HOSPITAL DRUG FORMULARY 2010
WAUSAU HOSPITAL DRUG FORMULARY 2010

... Parenteral Nutrition. Working in concert with Clinical Nutrition, pharmacists provide recommendations to prescribers regarding parenteral nutrition formulation, and will participate in monitoring and follow-up of nutrition therapy. On request, the pharmacist will complete the ordering process for th ...
Cardiovascular drugs: some important interaction
Cardiovascular drugs: some important interaction

... concentrations of CYP2D6 substrates ...
No Slide Title
No Slide Title

... Drug wholesalers, retailers, pharmacies & hospitals unless engaged in manufacturing operations beyond the usual dispensing or selling of drugs at retail ...
Herbal Remedies: Drug-Herb Interactions
Herbal Remedies: Drug-Herb Interactions

... b e e n used for medicinal purposes since the beginning of recorded time. Although most people in the United States believe that herbs are harmless plants, about one third of our drugs (including digitalis, morphine, atropine, and several chemotherapeutic agents) were developed from plants. So, inde ...
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Compounding

Pharmaceutical compounding (done in compounding pharmacies) is the creation of a particular pharmaceutical product to fit the unique need of a patient. To do this, compounding pharmacists combine or process appropriate ingredients using various tools. This may be done for medically necessary reasons, such as to change the form of the medication from a solid pill to a liquid, to avoid a non-essential ingredient that the patient is allergic to, or to obtain the exact dose(s) needed or deemed best of particular active pharmaceutical ingredient(s). It may also be done for more optional reasons, such as adding flavors to a medication or otherwise altering taste or texture. Compounding is most routine in the case of intravenous/parenteral medication, typically by hospital pharmacists, but is also offered by privately owned compounding pharmacies and certain retail pharmacies for various forms of medication. Whether routine or rare, intravenous or oral, etc., when a given drug product is made or modified to have characteristics that are specifically prescribed for an individual patient, it is known as ""traditional"" compounding.Due to the rising cost of compounding and the shortage of drugs, many hospitals have shown a tendency to rely more upon large-scale compounding pharmacies to meet their regular requirement, particularly of sterile-injectable medications. When compounding is done on bulk production of a given formulation rather than patient-specific production, it is known as ""non-traditional"" compounding (which, as discussed below, is arguably not ""compounding"" but rather ""manufacturing""). This development raises concerns about patient safety and makes a case for proper regulatory control and monitoring.
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