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DISSOLUTION ENHANCEMENT OF TELMISARTAN BY LIQUISOLID COMPACTS  , Research Article
DISSOLUTION ENHANCEMENT OF TELMISARTAN BY LIQUISOLID COMPACTS , Research Article

... is associated with the melting point of the drug and indicated the crystalline nature of telmisartan (figure 1). The thermogram of DCT (figure 2) exhibited endothermic peak at 270°C, which is the peak of the drug, indicated that there is no interaction between the drug and excipients used in the for ...
Safe and Effective Use of Psychotropic Drugs
Safe and Effective Use of Psychotropic Drugs

... refractory schizophrenia, but are contraindicated for patients who have a high probability of developing diabetes mellitus because of the reported risk these drugs have of causing diabetes mellitus. The use of quetiapine may reduce the problems of various adverse reactions common to typical antipsyc ...
ISMP Medication Safety Alert
ISMP Medication Safety Alert

... some respiratory therapy departments have been using a single metered dose inhaler (MDI) canister to administer medication to multiple patients. Proponents cite significant cost savings, efficiency, and fewer treatment delays, while advocating that crosscontamination is unlikely if the nozzle is dis ...
Elixir - Donnatal
Elixir - Donnatal

Illicit Internet availability of drugs subject to recall and patient safety
Illicit Internet availability of drugs subject to recall and patient safety

... for sale online. The first five pages of search results were examined and results were divided into three different marketing categories (see Table 1 for categories and definitions). Websites that were engaged in direct-to-patient sales (‘‘DTP’’) were also assessed for potential risk status by deter ...
The Extent and Implications of Poly
The Extent and Implications of Poly

... the major intoxicant in drivers. The Road Traffic Act 1994 set the legal limits of alcohol at 80 mg/100ml in blood and 107mg/100ml in urine. Increasingly, intoxication with drugs other than alcohol has been recognised, even though driving under the influence of drugs has been illegal under statute s ...
Urine Drug Screen
Urine Drug Screen

... are nasal inhalation (snorting) and smoking of the free-base form of the drug (Crack). Opiates are a class of natural and semi-synthetic drugs that include morphine, codeine and heroin. Opiates affect the central nervous system and produce feelings of euphoria. Abusers of opiates develop both a phys ...
Tiered 15/30/50 Var Pharmacy Plan
Tiered 15/30/50 Var Pharmacy Plan

... after a number of years. At that time any drug company can produce the drug, and the manufacturer must pass the same strict FDA standards of quality and product safety as the original manufacturer. Generic drugs are less expensive than brand name drugs because there is more competition and there is ...
Consumer Updates > Antibacterial Soap? You Can Skip It -
Consumer Updates > Antibacterial Soap? You Can Skip It -

SEMINAR ON DRUG EXCIPIENT COMPATIBILTY STUDY (As a …
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... o Place the drug in the solution of additives. o Both flint and amber vials are used. o This will provide information about -Susceptibility to oxidation. -Susceptibility to light exposure. -Susceptibility to heavy metals. o In case of oral liquids, compatibility with ethanol, glycerin ,sucrose, pres ...
FY M.Pharm Medicinal Natural Products
FY M.Pharm Medicinal Natural Products

... process development; Mathematical approach to pharmacokinetic modeling; one-compartment open models and data analysis; multiple-dose pharmacokinetics; twocompartment open models; physiological pharmacokinetic models; nonlinear pharmacokinetics; metabolite pharmacokinetics; pharmacokinetic-pharmacody ...
MICROSPONGE DRUG DELIVERY SYSTEM
MICROSPONGE DRUG DELIVERY SYSTEM

syllebus
syllebus

... (i) (i) Prescriptions –Reading and understanding of prescription; Latin terms commonly used (Detailed study is not necessary), Modern methods of prescribing, adoption of metric system. Calculations involved in dispensing. (ii) (ii) Incompatibilities in Prescriptions –Study of various types of incomp ...
Rebamipide - PIO Nas - Badan Pengawas Obat dan Makanan
Rebamipide - PIO Nas - Badan Pengawas Obat dan Makanan

... 2. Clinically Efficacy in Acute Gastritis and Acute Exacerbation of Chronic Gastritis MUCOSTA Tablets were studied in patients with acute gastritis or acute exacerbation of chronic gastritis. The drug achieved an 80% (370/461) global efficacy rate in the patient evaluated, with 76% (351/461) showing ...
Guidelines for the Use of Buprenorphine (Buprenex) in Rodents
Guidelines for the Use of Buprenorphine (Buprenex) in Rodents

MPA Spring Convention 2017 Edited
MPA Spring Convention 2017 Edited

... 1. Partial Fills - A prescription for a controlled substance in schedule II may be partially filled if— a) it is not prohibited by State law b) the prescription is written and filled in accordance with this title, regulations prescribed by the Attorney General, and State law c) the partial fill is r ...
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... AUC = Area Under the Curve – a measure of exposure to the drug t1/2 = Half-Life - the time taken for the plasma concentration to fall by half its original value ...
Ildong Pharmaceutical Receives a Marketing and
Ildong Pharmaceutical Receives a Marketing and

... This announcement contains forward-looking statements. These statements are based on expectations in light of the information currently available, assumptions that are subject to risks and uncertainties which could cause actual results to differ materially from these statements. Risks and uncertaint ...
Medicinal Chemistry Strategies to Address Bioactivation Liabilities in
Medicinal Chemistry Strategies to Address Bioactivation Liabilities in

... panel recommended lowering that amount to 625 milligrams. The current maximum total daily dose is 4 grams; the panel recommended reducing that as well, to 3.25 grams or less.” “People vary in their responses, so it's hard to say what an overdose is for any particular individual. Poison control exper ...
Economic Consequences of Drug Abuse in Sri Lanka
Economic Consequences of Drug Abuse in Sri Lanka

... for treatments. These people are not considered in this study as they were not recorded in the relevant reports. These people do not consume government facilities or medical treatments for drug abuse. But they may create negative economic externalities to the society through crimes and productivity ...
Dr. Carl Davis presentation
Dr. Carl Davis presentation

... by direct elimination (biliary and/or renal) or by enzyme-mediated metabolism – Generally this is a detoxication process that prevents accumulation of bioactive compounds in the body • can also produce reactive metabolites and toxicity • The contribution of these processes to total clearance of a dr ...
New Drug Application (NDA) Checklist
New Drug Application (NDA) Checklist

... copy of the general index of the entire application; (v) an index specific to that particular review section; (vi) letters of reference or authorization, if appropriate; and (vii) patent information. Applicants may request supplies of the jackets (with appropriate color coding) from the FDA or an ap ...
FORMULATION AND OPTIMISATION OF GASTRO RETENTIVE DRUG DELIVERY SYSTEM CONTAINING GLIPIZIDE
FORMULATION AND OPTIMISATION OF GASTRO RETENTIVE DRUG DELIVERY SYSTEM CONTAINING GLIPIZIDE

... patients with type II diabetes mellitus, glipizide GITS is at least as effective as the immediate-release formulation of glipizide in providing glycaemic control, and may have a greater effect on fasting plasma glucose levels4. ...
ABSTRACT:
ABSTRACT:

... can be achieved through an abbreviated application-utilizing data generated for the original drug application, or on the basis by which it was approved. However, a new drug delivered by inhalation would be subject to regulations governing NDAs and would require a complete package for review by regul ...
Drug A
Drug A

... 1- the pathways involved in drug absorption is complicated 2- drug is exposed to harsh gastrointestinal (GI) environments that may limit its absorption. Some drugs are absorbed from the stomach but, the duodenum is a major site of entry to the systemic circulation because of its larger absorptive su ...
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Compounding

Pharmaceutical compounding (done in compounding pharmacies) is the creation of a particular pharmaceutical product to fit the unique need of a patient. To do this, compounding pharmacists combine or process appropriate ingredients using various tools. This may be done for medically necessary reasons, such as to change the form of the medication from a solid pill to a liquid, to avoid a non-essential ingredient that the patient is allergic to, or to obtain the exact dose(s) needed or deemed best of particular active pharmaceutical ingredient(s). It may also be done for more optional reasons, such as adding flavors to a medication or otherwise altering taste or texture. Compounding is most routine in the case of intravenous/parenteral medication, typically by hospital pharmacists, but is also offered by privately owned compounding pharmacies and certain retail pharmacies for various forms of medication. Whether routine or rare, intravenous or oral, etc., when a given drug product is made or modified to have characteristics that are specifically prescribed for an individual patient, it is known as ""traditional"" compounding.Due to the rising cost of compounding and the shortage of drugs, many hospitals have shown a tendency to rely more upon large-scale compounding pharmacies to meet their regular requirement, particularly of sterile-injectable medications. When compounding is done on bulk production of a given formulation rather than patient-specific production, it is known as ""non-traditional"" compounding (which, as discussed below, is arguably not ""compounding"" but rather ""manufacturing""). This development raises concerns about patient safety and makes a case for proper regulatory control and monitoring.
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