Muddashetty RS, Nalavadi VC, Gross C, Yao X, Xing L, Laur O, Warren ST, and Bassell GJ. Reversible Inhibition of PSD-95 mRNA Translation by miR-125a, FMRP Phosphorylation, and mGluR Signaling. Molecular Cell 42: 673-688 (June 2011).
... mRNA translation by RISC components and miRNAs may be dynamically regulated by receptor signaling pathways. The ability of a cell to dynamically regulate RISC interactions with target mRNAs would allow for more precise temporal and spatial control of miRNA function than achieved solely by regulation ...
... mRNA translation by RISC components and miRNAs may be dynamically regulated by receptor signaling pathways. The ability of a cell to dynamically regulate RISC interactions with target mRNAs would allow for more precise temporal and spatial control of miRNA function than achieved solely by regulation ...
Two Anthranilate Synthase Genes in Arabidopsis
... ASAl and ASA2 are shown in Figure 4. For each gene, protein translation was assumed to begin at the first AUG codon downstream of the transcription start site(s). The ASAl gene is capable of encoding a protein of 595 amino acids with calculated molecular mass of 66212 D; ASA2 can encode a 69711-D pr ...
... ASAl and ASA2 are shown in Figure 4. For each gene, protein translation was assumed to begin at the first AUG codon downstream of the transcription start site(s). The ASAl gene is capable of encoding a protein of 595 amino acids with calculated molecular mass of 66212 D; ASA2 can encode a 69711-D pr ...
Ribosome readthrough
... The efficiency of translation termination (and the occurrence of readthrough) can vary depending on many factors 1) The efficiency of termination differs between normal stop codons and premature termination codons 2) Aminoglycosides can decrease the fidelity of translation, causing higher frequenci ...
... The efficiency of translation termination (and the occurrence of readthrough) can vary depending on many factors 1) The efficiency of termination differs between normal stop codons and premature termination codons 2) Aminoglycosides can decrease the fidelity of translation, causing higher frequenci ...
Chpt13_GeneticCode.doc
... the "language" of nucleic acids to that of proteins is the genetic code. Experiments testing the effects of frameshift mutations showed that the deletion or addition of 1 or 2 nucleotides caused a loss of function, whereas deletion or addition of 3 nucleotides allowed retention of considerable funct ...
... the "language" of nucleic acids to that of proteins is the genetic code. Experiments testing the effects of frameshift mutations showed that the deletion or addition of 1 or 2 nucleotides caused a loss of function, whereas deletion or addition of 3 nucleotides allowed retention of considerable funct ...
MicroRNAs act sequentially and asymmetrically to
... Christian Frokjaer-Jensen, Shawn Lockery and Oliver Hobert ...
... Christian Frokjaer-Jensen, Shawn Lockery and Oliver Hobert ...
Drosophila Genetics Simulation
... purine adenine (A) pairs with the pyrimidine uracil (U). The strand of mRNA travels out to the cytoplasm of the cell. In the cytoplasm a ribosome binds to the mRNA strand at a specific point called a start codon. The ribosome reads three mRNA nucleotides at a time—these base triplets are called codo ...
... purine adenine (A) pairs with the pyrimidine uracil (U). The strand of mRNA travels out to the cytoplasm of the cell. In the cytoplasm a ribosome binds to the mRNA strand at a specific point called a start codon. The ribosome reads three mRNA nucleotides at a time—these base triplets are called codo ...
Introduction to the Analysis of Microarray Data
... consists of a glass slide on which thousands of distinct DNA sequences have been affixed. Each dot (or “feature”) on the slide represents the sequence of a different plant gene. After the unbound probe is washed away, a special slide scanner excites each feature on the array with a laser and measure ...
... consists of a glass slide on which thousands of distinct DNA sequences have been affixed. Each dot (or “feature”) on the slide represents the sequence of a different plant gene. After the unbound probe is washed away, a special slide scanner excites each feature on the array with a laser and measure ...
Extensive tRNA gene changes in synthetic Brassica
... Transfer RNA (tRNA) is usually 75-95 bp in length, and is classed as non-coding RNA. It is ubiquitous in all organisms, and accounts for about 15% of all RNAs in the cell, in between rRNA (approximately 75%) and mRNA (about 5%) in abundance. The roles and functions of tRNA have been widely studied. ...
... Transfer RNA (tRNA) is usually 75-95 bp in length, and is classed as non-coding RNA. It is ubiquitous in all organisms, and accounts for about 15% of all RNAs in the cell, in between rRNA (approximately 75%) and mRNA (about 5%) in abundance. The roles and functions of tRNA have been widely studied. ...
Document
... The transcriber is RNA polymerase It binds to one DNA strand at a site called the promoter It then moves along the DNA pairing complementary nucleotides It disengages at a stop signal Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
... The transcriber is RNA polymerase It binds to one DNA strand at a site called the promoter It then moves along the DNA pairing complementary nucleotides It disengages at a stop signal Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
The Living World - Chapter 9 - McGraw Hill Higher Education
... The transcriber is RNA polymerase It binds to one DNA strand at a site called the promoter It then moves along the DNA pairing complementary nucleotides It disengages at a stop signal Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
... The transcriber is RNA polymerase It binds to one DNA strand at a site called the promoter It then moves along the DNA pairing complementary nucleotides It disengages at a stop signal Copyright ©The McGraw-Hill Companies, Inc. Permission required for reproduction or display ...
chapt06b_lecture
... protomers, heart (H) and muscle (M). Of the five LDH isozymes, LDH1 (H4) and LDH2 (H3M) are found only in heart muscle and red blood cells. Again, electrophoresis patterns can be used to diagnose an infarct. The next slide shows normal and abnormal patterns for LDH1-5. 6P2-34 ...
... protomers, heart (H) and muscle (M). Of the five LDH isozymes, LDH1 (H4) and LDH2 (H3M) are found only in heart muscle and red blood cells. Again, electrophoresis patterns can be used to diagnose an infarct. The next slide shows normal and abnormal patterns for LDH1-5. 6P2-34 ...
CD99 and CD99L2 are Mediators of Homotypic Adhesion in Human
... – H3K79: ambiguous, but known to activate Hoxa9 transcription – Bivalence: both activating and silencing modifications present. ...
... – H3K79: ambiguous, but known to activate Hoxa9 transcription – Bivalence: both activating and silencing modifications present. ...
splice sites at the termini generating a novel intron from a dSpm
... The A2 transcription unit was characterized. Comparison with the genomic clones shows that A2 is a gene devoid of introns. The dSpm element of the a2-ml (original state) allele has perfect terinini; in contrast, the dSpm of the class II state allele lacks all of the tnpA binding motifs at one end, b ...
... The A2 transcription unit was characterized. Comparison with the genomic clones shows that A2 is a gene devoid of introns. The dSpm element of the a2-ml (original state) allele has perfect terinini; in contrast, the dSpm of the class II state allele lacks all of the tnpA binding motifs at one end, b ...
Using dynamics-based comparisons to predict nucleic acid binding
... Dynamics-based alignment establishes one-to-one correspondences between groups of amino acids experiencing similar large-scale motions in two given proteins. The method, described in detail in Zen et al. (2008), is based on an iterative scheme which starts with a tentative selection of the amino aci ...
... Dynamics-based alignment establishes one-to-one correspondences between groups of amino acids experiencing similar large-scale motions in two given proteins. The method, described in detail in Zen et al. (2008), is based on an iterative scheme which starts with a tentative selection of the amino aci ...
Gene silencing in Caenorhabditis elegans by transitive RNA
... al. 2000), double-stranded RNA-binding proteins (Tabara et al. 2002), as well as additional Argonaute members (Tabara et al. 1999; Fagard et al. 2000). In several organisms, Argonaute homologs are not required to produce siRNAs, suggesting this family may function downstream of dsRNA processing (Par ...
... al. 2000), double-stranded RNA-binding proteins (Tabara et al. 2002), as well as additional Argonaute members (Tabara et al. 1999; Fagard et al. 2000). In several organisms, Argonaute homologs are not required to produce siRNAs, suggesting this family may function downstream of dsRNA processing (Par ...
Authors` pre-proof version - University of Connecticut
... closely related to the donor are still living. However, in ancient transfers that have occurred before the divergence of major domains, or even prior to the time of LUCA, close relatives of donor lineages are usually extinct, making it difficult or even impossible to determine transfer scenarios. Ge ...
... closely related to the donor are still living. However, in ancient transfers that have occurred before the divergence of major domains, or even prior to the time of LUCA, close relatives of donor lineages are usually extinct, making it difficult or even impossible to determine transfer scenarios. Ge ...
Cell-Free Protein Expression Systems
... Rabbit Reticulocyte Lysate (RRL), Nuclease-Treated, is optimized for mRNA translation by the addition of several supplements. These include hemin, which prevents activation of the heme-regulated eIF-2a kinase; an energy-generating system consisting of phosphocreatine kinase and phosphocreatine; and ...
... Rabbit Reticulocyte Lysate (RRL), Nuclease-Treated, is optimized for mRNA translation by the addition of several supplements. These include hemin, which prevents activation of the heme-regulated eIF-2a kinase; an energy-generating system consisting of phosphocreatine kinase and phosphocreatine; and ...
The Invention of Proteomic Code and mRNA
... idea was, of course, rejected because it proposed that even the “non-sense” DNA strand might be expressed and makes some sense, which was an absurdity at that time. An early effort to confirm this theory, using (rather undeveloped) bioinformatical methods, failed [37]. There was a short come-back of ...
... idea was, of course, rejected because it proposed that even the “non-sense” DNA strand might be expressed and makes some sense, which was an absurdity at that time. An early effort to confirm this theory, using (rather undeveloped) bioinformatical methods, failed [37]. There was a short come-back of ...
Function of ribosomes and glutamyl-tRNA isoacceptors
... Function of glutamyl-tRNA &oacceptors in polysomal protein synthesis In a previous report, it was shown that changes in the relatige amounts of the muscle glutamylt R N A isoacceptors take place over the course of the regeneration process [6]. Three glutamyl-tRNA species could be separated by RPC-5 ...
... Function of glutamyl-tRNA &oacceptors in polysomal protein synthesis In a previous report, it was shown that changes in the relatige amounts of the muscle glutamylt R N A isoacceptors take place over the course of the regeneration process [6]. Three glutamyl-tRNA species could be separated by RPC-5 ...
Journal of Bacteriology
... host-specific nod gene products, resulting in effective nodules on a limited range of host plants (1, 16, 38, 48). Other nod genes identified in R. leguminosarum bv. viciae are nodlJ, nodMNT (6, 54, 55), and nodO (11, 15). Mutations in these genes have more or less severe effects on nodulation, depe ...
... host-specific nod gene products, resulting in effective nodules on a limited range of host plants (1, 16, 38, 48). Other nod genes identified in R. leguminosarum bv. viciae are nodlJ, nodMNT (6, 54, 55), and nodO (11, 15). Mutations in these genes have more or less severe effects on nodulation, depe ...
DNA and RNA:
... This control comes from the genetic information stored in the cell’s deoxyribonucleic acid (DNA) molecule(s). The DNA molecule contains a type of blueprint for making the many different types of proteins that the cell needs. The portion of the DNA strand that codes for a particular protein is called ...
... This control comes from the genetic information stored in the cell’s deoxyribonucleic acid (DNA) molecule(s). The DNA molecule contains a type of blueprint for making the many different types of proteins that the cell needs. The portion of the DNA strand that codes for a particular protein is called ...
Using the Hepatitis C Virus RNA-Dependent RNA Polymerase as a
... 5. Catalytic Mechanism and Polymerase Reaction Steps All known polymerases synthesize nucleic acid in the 51 to 31 direction [9]. Thus, replication in positive-stranded RNA viruses occurs via a negative-stranded intermediate. The polymerase reaction has three stages: initiation, elongation and termi ...
... 5. Catalytic Mechanism and Polymerase Reaction Steps All known polymerases synthesize nucleic acid in the 51 to 31 direction [9]. Thus, replication in positive-stranded RNA viruses occurs via a negative-stranded intermediate. The polymerase reaction has three stages: initiation, elongation and termi ...