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Understanding infectious disease
Understanding infectious disease

... Other infectious agents are more readily able to cause disease and may only be present in some herds. These are called primary pathogens. However, they may still be found in apparently healthy herds and animals. Animals with little or no immunity to these pathogens will often show severe signs of di ...
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... or inappropriate use of antimicrobial agents; however, the definitions used to classify drug resistance, as well as the public health control measures, vary. These pathogens are increasingly resistant to more drugs, and new descriptive terms such as multidrug resistant (MDR) and, for TB, extensively ...
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... to prevent the spread of the disease. Chagas: a parasitic disease, commonly transmitted through insects, blood transfusions or from mother to baby during pregnancy. If left untreated, the disease ...
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... How long will the disease persist in the population? Would vaccination prevent an epidemic? If so, what type of vaccination program is most efficient? What other measures could be taken to prevent an epidemic? Basic Reproductive Number, R0 Whether or not an epidemic occurs depends on many factors. A ...
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... completely but very small litters (1 or 2 piglets) can be produced if embryonic death occurs after 14 day, but before skin and bone are formed at 30-35 days. Later infection of the litter, once foetal structure is formed, leads to death of the foetuses and partial ...
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... Recent Influenza A infections Human infections with human influenza viruses H1N1 H1N2 H3N2 CDC: The 2014-2015 trivalent influenza vaccine is made from the hemagglutinin of the following three viruses: • an A/California/7/2009-like (H1N1) virus, • an A/Switzerland/9715293/ 2013- like (H3N2) virus • ...
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Live attenuated vaccines - WHO Vaccine Safety Basics

... Live attenuated vaccine (LAV)A vaccine prepared from living micro-organisms (viruses, bacteria currently available) that have been weakened under laboratory conditions. LAV vaccines will replicate in a vaccinated individual and produce an immune response but usually cause mild or no disease. are der ...
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vitamin c in the prophylaxis and therapy of infectious diseases

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... D. Anticipating emerging diseases: vector competence to novel viruses. Since the 1970’s, vector-borne emerging diseases have arisen as major public health issues throughout the world. Recent outbreaks of West Nile virus in North America and chikungunya virus in the Indian Ocean have emphasized the n ...
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... • Universal vaccination is now offered to all infants as part of the MMR regimen in the USA, UK and a number of other countries. • Some countries such as the Czech Republic continue to selectively vaccinate schoolgirls before they reach childbearing age. ...
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Eradication of infectious diseases



Eradication is the reduction of an infectious disease's prevalence in the global host population to zero. It is sometimes confused with elimination, which describes either the reduction of an infectious disease's prevalence in a regional population to zero, or the reduction of the global prevalence to a negligible amount. Further confusion arises from the use of the term eradication to refer to the total removal of a given pathogen from an individual (also known as clearance of an infection), particularly in the context of HIV and certain other viruses where such cures are sought.Selection of infectious diseases for eradication is based on rigorous criteria, as both biological and technical features determine whether a pathogenic organism is (at least potentially) eradicable. The targeted organism must not have a non-human reservoir (or, in the case of animal diseases, the infection reservoir must be an easily identifiable species, as in the case of rinderpest), and/or amplify in the environment. This implies that sufficient information on the life cycle and transmission dynamics is available at the time an eradication initiative is programmed. An efficient and practical intervention (e.g., a vaccine or antibiotic) must be available to interrupt transmission of the infective agent. Studies of measles in the pre-vaccination era led to the concept of the Critical community size, the size of the population below which a pathogen ceases to circulate. Use of vaccination programmes before the introduction of an eradication campaign can reduce the susceptible population. The disease to be eradicated should be clearly identifiable, and an accurate diagnostic tool should exist. Economic considerations, as well as societal and political support and commitment, are other crucial factors that determine eradication feasibility.Eight attempts have been made to date to eradicate infectious diseases: two successful programs targeting smallpox and rinderpest; four ongoing programs targeting poliomyelitis, yaws, dracunculiasis and malaria; and two former programs targeting hookworm and yellow fever. Five more infectious diseases have been identified as of April 2008 as potentially eradicable with current technology by the Carter Center International Task Force for Disease Eradication—measles, mumps, rubella, lymphatic filariasis and cysticercosis.
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