One 2-fold axis of symmetry
... through 180˚ gives an indistinguishable structure. Thus, there is a 2-fold axis of symmetry, also called a dyad. In haemoglobin we are concerned with a tetramer. (Although there are two different subunits, and , we regard them as practically identical and qualify our statements by referring to ps ...
... through 180˚ gives an indistinguishable structure. Thus, there is a 2-fold axis of symmetry, also called a dyad. In haemoglobin we are concerned with a tetramer. (Although there are two different subunits, and , we regard them as practically identical and qualify our statements by referring to ps ...
PSI - European Bioinformatics Institute
... • Given a set of uncharacterised sequences, we usually want to know: ...
... • Given a set of uncharacterised sequences, we usually want to know: ...
Post Exercise Carbohydrates May Be Counter
... skeletal muscle protein synthesis and an overall net balance. 3 Exercise provides an adaptive response so that the body is able to make use of any nutrition supplied post exercise. Nutrient intake on its own provides a storage response so that if one is fed or receives an infusion of mixed amino aci ...
... skeletal muscle protein synthesis and an overall net balance. 3 Exercise provides an adaptive response so that the body is able to make use of any nutrition supplied post exercise. Nutrient intake on its own provides a storage response so that if one is fed or receives an infusion of mixed amino aci ...
Sequence-based analyses - Protein Information Resource
... http://pir.georgetown.edu/pirwww/search/blast.shtml ...
... http://pir.georgetown.edu/pirwww/search/blast.shtml ...
European Journal of Biochemistry
... should n o t grossly alter the conformation or localizatim of (Fig. I b). Subseqiiently. t h i s purified plasmid and p.iP79 D N A M C I W the protein. The following lines of evidence indicate that the wparately digested with Hglll and G o R I . Plasmid DX/\ fragments PhoE* protein is norinally fold ...
... should n o t grossly alter the conformation or localizatim of (Fig. I b). Subseqiiently. t h i s purified plasmid and p.iP79 D N A M C I W the protein. The following lines of evidence indicate that the wparately digested with Hglll and G o R I . Plasmid DX/\ fragments PhoE* protein is norinally fold ...
Membrane Fusion
... intermediate 2) Insertion of additional residues N-terminal to the transmembrane domains inhibits fusion ...
... intermediate 2) Insertion of additional residues N-terminal to the transmembrane domains inhibits fusion ...
Tying rings for sex
... extent, enough material was digested when pilus suspensions were exposed to high concentrations of the enzymes [12]. A time course of the tryptic digestion of pilin monitored by mass spectrometry revealed another feature unique to circular proteins: the molecular mass increases by 18 daltons when th ...
... extent, enough material was digested when pilus suspensions were exposed to high concentrations of the enzymes [12]. A time course of the tryptic digestion of pilin monitored by mass spectrometry revealed another feature unique to circular proteins: the molecular mass increases by 18 daltons when th ...
Comment in GO: This term is intended to
... macromolecular complex (GO:0032991) – A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. protein complex (GO:0043234) – Any macromolecular complex composed of two or more polypeptide subunits, whic ...
... macromolecular complex (GO:0032991) – A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. protein complex (GO:0043234) – Any macromolecular complex composed of two or more polypeptide subunits, whic ...
Chapter 15. Recognition of foreign molecules by the immune system
... Structural details and comparisons of the coreceptor-Lck complexes. In addition to metal coordination, hydrophobic cores stabilize the CD4 (A) and CD8 (B) complexes. In CD4, phosphorylation of Ser 408 (and to a lesser extent Ser415) promotes CD4 internalization. These residues are exposed in the co ...
... Structural details and comparisons of the coreceptor-Lck complexes. In addition to metal coordination, hydrophobic cores stabilize the CD4 (A) and CD8 (B) complexes. In CD4, phosphorylation of Ser 408 (and to a lesser extent Ser415) promotes CD4 internalization. These residues are exposed in the co ...
Chapter 2 - University of the Free State
... •At higher salt concentrations, weak interactions between the disordered water molecules are further disrupted, i.e., the molecules become even less ordered •transfer of a water molecule from the ordered environment next to the hydrophobic droplet to the disordered state, will have a larger ∆S compo ...
... •At higher salt concentrations, weak interactions between the disordered water molecules are further disrupted, i.e., the molecules become even less ordered •transfer of a water molecule from the ordered environment next to the hydrophobic droplet to the disordered state, will have a larger ∆S compo ...
Description of the KDD-Cup 2004 Protein Data
... computes numerous protein features based on the input sequence (for detailed description of the features see below). The different features are combined to assign a global score of similarity to other fully annotated proteins, suggesting likely templates for modeling. LOOPP is also building atomical ...
... computes numerous protein features based on the input sequence (for detailed description of the features see below). The different features are combined to assign a global score of similarity to other fully annotated proteins, suggesting likely templates for modeling. LOOPP is also building atomical ...
Essential amino acids - Feed-to-Food
... • When steam is used, the temperature of pellets after leaving the die is generally higher • Amino acids were determined with HPLC using the AccQTag method. This method is based on a in comparison with that of the conditioned meal due to the frictional heat in the die derivatizing reagent developed ...
... • When steam is used, the temperature of pellets after leaving the die is generally higher • Amino acids were determined with HPLC using the AccQTag method. This method is based on a in comparison with that of the conditioned meal due to the frictional heat in the die derivatizing reagent developed ...
Acetylcholine Receptor-associated 43K Protein Contains Covalently
... to play a key role in the maintenance of nAchR clusters is a specialized network of structural proteins localized to the cytoplasmic membrane face of the clusters (25, 52). Among proteins that have been identifed in this meshwork in muscle are ~t-actinin (4), filamin (4), vinculin (4), talin (54), a ...
... to play a key role in the maintenance of nAchR clusters is a specialized network of structural proteins localized to the cytoplasmic membrane face of the clusters (25, 52). Among proteins that have been identifed in this meshwork in muscle are ~t-actinin (4), filamin (4), vinculin (4), talin (54), a ...
sorghum protein - Simply Sorghum
... • Sorghum is an important source of plant-based protein, containing 10.62 g/100 g. • Plant-based protein sources, like sorghum, are high in fiber, vitamins and antioxidants, which promote bone, heart and immune health. • Phytochemical compounds, including condensed tannins and anthocyanins, mainl ...
... • Sorghum is an important source of plant-based protein, containing 10.62 g/100 g. • Plant-based protein sources, like sorghum, are high in fiber, vitamins and antioxidants, which promote bone, heart and immune health. • Phytochemical compounds, including condensed tannins and anthocyanins, mainl ...
2.7 DNA Transcription_translation
... Because of hydrogen bonds, tRNA actually twists and folds into a three-dimensional molecule tRNA is roughly L-shaped ...
... Because of hydrogen bonds, tRNA actually twists and folds into a three-dimensional molecule tRNA is roughly L-shaped ...
Sporopollenin biosynthetic enzymes interact and constitute a
... After washing, proteins were eluted and the presence of the preys in the protein complexes was tested by immunoblotting using specific antibodies. Results are presented in Figure 2. When ACOS5 was used as bait, PKSA and TKPR1 were found in protein complexes bound to the affinity beads whereas no pre ...
... After washing, proteins were eluted and the presence of the preys in the protein complexes was tested by immunoblotting using specific antibodies. Results are presented in Figure 2. When ACOS5 was used as bait, PKSA and TKPR1 were found in protein complexes bound to the affinity beads whereas no pre ...
Proteomic sensitivity to dietary manipulations in rainbow trout
... were found in free amino acid pools in either liver or muscle between diets. Protein extraction followed by high-resolution two-dimensional electrophoresis, coupled with gel image analysis, allowed identification and expression of hundreds of protein. Individual proteins of interest were then subjec ...
... were found in free amino acid pools in either liver or muscle between diets. Protein extraction followed by high-resolution two-dimensional electrophoresis, coupled with gel image analysis, allowed identification and expression of hundreds of protein. Individual proteins of interest were then subjec ...
Signaling by Serine/Threonine Kinase Receptors
... Receptors with intrinsic serine/threonine kinase activity ...
... Receptors with intrinsic serine/threonine kinase activity ...
Document
... Genome projects 2045 ongoing projects, 348 completed, mostly from microbes (228 with more than 1500 genes, more or less correctly annotated) 144,116,054,623 nucleotides at International Nucleotide Sequence Database Collaboration (INSDC) Microbes make 50% of the Earth protoplasm 40-50% coding DNA se ...
... Genome projects 2045 ongoing projects, 348 completed, mostly from microbes (228 with more than 1500 genes, more or less correctly annotated) 144,116,054,623 nucleotides at International Nucleotide Sequence Database Collaboration (INSDC) Microbes make 50% of the Earth protoplasm 40-50% coding DNA se ...
Localization of Low-sulfur Keratin Proteins in the Wool Follicle Using
... The location of proteins in thin sections of sheep skin reacting with the panel of monoclonal antibodies was investigated using indirect immunofluorescent. The results are listed in Table I and shown schematically in Fig. 3. Despite the disadvantage that the monoclonal antibodies all recognize more ...
... The location of proteins in thin sections of sheep skin reacting with the panel of monoclonal antibodies was investigated using indirect immunofluorescent. The results are listed in Table I and shown schematically in Fig. 3. Despite the disadvantage that the monoclonal antibodies all recognize more ...
The archaeal origins of the eukaryotic translational system
... both the full 67- and the 33-protein subset of only those common to Archaea and Eukarya provided a clear three-way separation between Eukarya, Crenarchaea and Euryarchaea (Figure 4b). The same relationship was obtained using only the blocks common to both Eukarya and Archaea found in the 34 universa ...
... both the full 67- and the 33-protein subset of only those common to Archaea and Eukarya provided a clear three-way separation between Eukarya, Crenarchaea and Euryarchaea (Figure 4b). The same relationship was obtained using only the blocks common to both Eukarya and Archaea found in the 34 universa ...
Protein import into the nucleus - Universitätsklinikum des Saarlandes
... The nuclear pore complex (NPC) is the site of all transport of macromolecules between the cytoplasm and the nucleoplasm. This review will focus on new findings on protein import into the nucleus. Export of proteins and import/export of R N A have been reviewed recently [1-4]. Molecules of up to ,~ 5 ...
... The nuclear pore complex (NPC) is the site of all transport of macromolecules between the cytoplasm and the nucleoplasm. This review will focus on new findings on protein import into the nucleus. Export of proteins and import/export of R N A have been reviewed recently [1-4]. Molecules of up to ,~ 5 ...
Protein
Proteins (/ˈproʊˌtiːnz/ or /ˈproʊti.ɨnz/) are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within living organisms, including catalyzing metabolic reactions, DNA replication, responding to stimuli, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than about 20-30 residues, are rarely considered to be proteins and are commonly called peptides, or sometimes oligopeptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residues in a protein is defined by the sequence of a gene, which is encoded in the genetic code. In general, the genetic code specifies 20 standard amino acids; however, in certain organisms the genetic code can include selenocysteine and—in certain archaea—pyrrolysine. Shortly after or even during synthesis, the residues in a protein are often chemically modified by posttranslational modification, which alters the physical and chemical properties, folding, stability, activity, and ultimately, the function of the proteins. Sometimes proteins have non-peptide groups attached, which can be called prosthetic groups or cofactors. Proteins can also work together to achieve a particular function, and they often associate to form stable protein complexes.Once formed, proteins only exist for a certain period of time and are then degraded and recycled by the cell's machinery through the process of protein turnover. A protein's lifespan is measured in terms of its half-life and covers a wide range. They can exist for minutes or years with an average lifespan of 1–2 days in mammalian cells. Abnormal and or misfolded proteins are degraded more rapidly either due to being targeted for destruction or due to being unstable.Like other biological macromolecules such as polysaccharides and nucleic acids, proteins are essential parts of organisms and participate in virtually every process within cells. Many proteins are enzymes that catalyze biochemical reactions and are vital to metabolism. Proteins also have structural or mechanical functions, such as actin and myosin in muscle and the proteins in the cytoskeleton, which form a system of scaffolding that maintains cell shape. Other proteins are important in cell signaling, immune responses, cell adhesion, and the cell cycle. Proteins are also necessary in animals' diets, since animals cannot synthesize all the amino acids they need and must obtain essential amino acids from food. Through the process of digestion, animals break down ingested protein into free amino acids that are then used in metabolism.Proteins may be purified from other cellular components using a variety of techniques such as ultracentrifugation, precipitation, electrophoresis, and chromatography; the advent of genetic engineering has made possible a number of methods to facilitate purification. Methods commonly used to study protein structure and function include immunohistochemistry, site-directed mutagenesis, X-ray crystallography, nuclear magnetic resonance and mass spectrometry.