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AusPAR: Retigabine - Therapeutic Goods Administration
AusPAR: Retigabine - Therapeutic Goods Administration

ICH E10
ICH E10

... prolongation of the QT interval. Because of its inverse relationship to heart rate, the measured QT interval is routinely corrected by means of various formulae to a less heart rate dependent value known as the QTc interval. It is not clear, however, whether arrhythmia development is more closely re ...
Moore - AL.com
Moore - AL.com

... and in many situations, focused on the use of the drug for atrial fibrillation and failed to warn prescribing physicians of the potential dangers associated with amiodarone toxicity and dangers to atrial fibrillation patients. Defendant Wyeth’s campaigns were so pervasive and effective that for an e ...
Anabolic Steroids hardcore info
Anabolic Steroids hardcore info

... During a cycle people may take a combination of two or more drugs. This combination is known as the stack or stacking. When stacking more than one steroid the dose of each can be reduced, with the same effects obtained. This is because more receptors are used than when using a single steroid. Some p ...
AusPAR: Docetaxel
AusPAR: Docetaxel

... An AusPAR is prepared for submissions that relate to new chemical entities, generic medicines, major variations, and extensions of indications. An AusPAR is a static document, in that it will provide information that relates to a submission at a particular point in time. A new AusPAR will be develop ...
- Journal of Allergy and Clinical Immunology
- Journal of Allergy and Clinical Immunology

... immunologically mediated. Unlike most adverse drug reactions, allergic drug reactions are unpredictable. Whereas some drug-induced allergic reactions may be easily classified into one of the four Gell and Coombs hypersensitivity categories, many others that appear to have an immunologic component ca ...
Core Aspects of Clinical Development and Trials in Chronic
Core Aspects of Clinical Development and Trials in Chronic

... events (i.e., diarrhea) tend to subside after the first dose. In general, there is very limited information on the pharmacokinetic-pharmacodynamic relationship for drugs for this indication. These first-in-man studies are typically followed by pilot dose-ranging safety and efficacy trials in the aff ...
Fixed combination of arthemether and lumefantrine
Fixed combination of arthemether and lumefantrine

... resistant falciparum malaria, was added to the Model List of Essential Drugs in 1999 (WHO, 2000a). Artemisinin-based combinations have several distinct advantages in that (i). they produce rapid clinical and parasitological cure; (ii). there is as yet no documented parasite resistance to them; (iii ...
SDCEP-Drug-Prescribing-For-Dentistry-3rd-Edition
SDCEP-Drug-Prescribing-For-Dentistry-3rd-Edition

... information provided in the BNF is accurate and up-to-date as at the date of publication, but changes do regularly occur and the Publisher does not warrant that it is accurate. The BNF is designed as a digest for rapid reference and it may not always include all information necessary for prescribing ...
Substance Abuse in WV (Special CME Issue)
Substance Abuse in WV (Special CME Issue)

... ramifications that cross all socioeconomic and demographic boundaries. In West Virginia it is ...
Codeine and breastfeeding: Is it safe and what are the alternatives?
Codeine and breastfeeding: Is it safe and what are the alternatives?

... cyanosis, and infant death (4, 10-12). A one-week-old infant was evaluated for conjunctivitis and in the process found to have bradycardia. The mother had ingested a single 30mg dose of codeine six days earlier. The infant’s heart rate normalized over 24 hours and remained stable over the next few m ...
Wise List - Janusinfo
Wise List - Janusinfo

... List’. The ‘Wise List’ is issued by the regional DTC. All principles for selecting drugs, communicating pharmacotherapeutic recommendations and monitoring the impact of the ‘Wise List’ on prescribing were documented in the protocols and the guidelines from the regional DTC. Our presentation is based ...
Statins - Consumer Health Choices
Statins - Consumer Health Choices

... can build up on the walls of blood vessels. This buildup is called plaque. It clogs the blood vessels and can lead to a heart attack or stroke. ...
AusPAR: Docetaxel - Therapeutic Goods Administration
AusPAR: Docetaxel - Therapeutic Goods Administration

... All formulations include polysorbate 80 (chemical structure shown in Figure 2) which is a sugar extensively modified by polyoxyethylene substitution and esterification. Polysorbate 80 is a non-ionic surfactant which forms micelles in water. ...
Committee on Drugs 1997;99;918 DOI: 10.1542/peds.99.6.918
Committee on Drugs 1997;99;918 DOI: 10.1542/peds.99.6.918

... and/or antipyretics. Some nonprescription preparaThe recommendations in this statement do not indicate an exclusive course of treatment or serve as a standard of medical care. Variations, taking into account individual circumstances, may be appropriate. PEDIATRICS (ISSN 0031 4005). Copyright © 1997 ...
Afghanistan Synthetic Drugs Situation Assessment
Afghanistan Synthetic Drugs Situation Assessment

... purity and, in addition to methamphetamine, may contain a variety of other substances. Crystalline methamphetamine is usually of a much higher purity than the tablet form. Presently, methamphetamine might be sold under various street names in Afghanistan (see Table 1, Chapter 1). New psychoactive s ...
Glucosamine + Chondroitin with Manganese
Glucosamine + Chondroitin with Manganese

... Cartilage Composition: Glucosamine promotes the synthesis of the glycosaminoglycan chondroitin sulfate. Chondroitin sulfate is responsible for building the ground substance of cartilage, molecules known as proteoglycans. Studies have indicated that glucosamine HCl has the ability to support healthy ...
Problems of anabolic steroids in sport.
Problems of anabolic steroids in sport.

... the actual doping substance to be identified, the gas chromatographic/mass spectrometric technique was required and unfortunately not all drugs had been examined by this technique to produce definitive tests. Thus action was not taken on results which for a few years represented research operations. ...
Nessun titolo diapositiva
Nessun titolo diapositiva

... • Control Group: 1-3 µL of 100-300 µm beads injected • Dose ranging study: 1-3 µL of loaded 100-300 µm beads injected. Histogical evaluation 12 days post-tumour implant • Survival study: 1 µL of 100-300 µm loaded beads injected. Animal activity and well-being assessed twice daily. Euthanised if low ...
myostimulant effect of leaves of cassia occidentalis
myostimulant effect of leaves of cassia occidentalis

... Originally from South America (Ake-Assi, 1983), Cassia occidentalis (Caesalpiniaceae) has become a pantropical species thanks to its great capacity for expansion. In West Africa and particularly in Senegal and Côte d'Ivoire, it is found around villages and in fields where it can be a formidable weed ...
Review Article Pro- and Anticonvulsant Effects of Anesthetics (Part 11)
Review Article Pro- and Anticonvulsant Effects of Anesthetics (Part 11)

... than 75% of the patients (176,181). The well-known EEG activating effects of N,O cannot be ruled out as an additive factor in these two reports. Furthermore, correlation between EEG and clinical seizure activity may have been prevented by concomitant nondepolarizing neuromuscular blockade. Interesti ...
Instructions for Use
Instructions for Use

... the following adverse effects have been reported most frequently: rash, edema, headache, dizziness, asthenia, nausea, vomiting, and diarrhea. Other adverse effects that have been reported include: seizure, ataxia, dyspnea, abdominal pain, paresthesia, urticaria, and contact dermatitis. In case of ac ...
LOCAL DRUG DELIVERY IN PERIODONTICS: A STRATEGIC INTERVENTION Review Article
LOCAL DRUG DELIVERY IN PERIODONTICS: A STRATEGIC INTERVENTION Review Article

... mechanical debridement to disrupt the subgingival flora and provide clean, smooth and biologically compatible root surfaces. Unfortunately, in some instances, the complex anatomy of the root and the contours of the lesion may hamper the treatment and prevent sufficient reduction of the bacterial loa ...
RESEARCH NOTE–PRESCRIBING DIAMORPHINE FOR MEDICAL
RESEARCH NOTE–PRESCRIBING DIAMORPHINE FOR MEDICAL

... by a license holder, a practitioner, or a pharmacist. A pharmacist may supply the drug to a patient only on the authority of an appropriate prescription where special regulations apply. These concern the handwriting of the prescriber, the dose, the form, the strength of the preparation, and the tota ...
schering-plough gmp consent decree puts drug
schering-plough gmp consent decree puts drug

... Services (HHS) Secretary Tommy Thompson requesting that the department, which oversees the FDA, investigate Schering-Plough for allegedly shipping asthma drug inhalers that may not have contained the active ingredient. “If you knowingly ship out products without active ingredient, as we believe they ...
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Pharmacognosy



Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.
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