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powders
powders

... In the use of this Aerohaler, inhalation by the patient causes a small ball to strike a cartridge containing the drug. The force of the ball shakes the proper amount of the powder free, permitting its inhalation. Another device, the Spin haler turbo-inhaler (Fisons), is a propeller-driven device de ...
Propoxyphene Assay
Propoxyphene Assay

... Propoxyphene and propoxyphene napsylate, a propoxyphene salt, are mildly effective narcotic analgesics used to treat mild to moderate pain. Propoxyphene is structurally related to methadone and produces central nervous system effects similar to those of morphine-like opioids. When given orally, prop ...
Disposal of Unwanted Medicines A Resource for Action in Your Community www.iiseagrant.org/unwantedmeds.org
Disposal of Unwanted Medicines A Resource for Action in Your Community www.iiseagrant.org/unwantedmeds.org

... Disposal to trash is considered to be an interim solution because medicines placed in landfills are likely to slow the transport of the chemicals to waterways or sludge, but landfill leachate ultimately reaches wastewater treatment plants and local streams and rivers (Barnes et al. 2004). Illinois-I ...
pdf
pdf

... Disposal to trash is considered to be an interim solution because medicines placed in landfills are likely to slow the transport of the chemicals to waterways or sludge, but landfill leachate ultimately reaches wastewater treatment plants and local streams and rivers (Barnes et al. 2004). Illinois-I ...
[4] The Liposomal Formulation of Doxorubicin
[4] The Liposomal Formulation of Doxorubicin

... used drugs for the treatment of both hematological and solid tumors. The therapy-limiting toxicity for this drug is cardiomyopathy, which may lead to congestive heart failure and death. Approximately 2% of patients who have received a cumulative (lifetime) doxorubicin dose of 450–500 mg=m2 will expe ...
PDF - AIDS Research and Therapy
PDF - AIDS Research and Therapy

... Background: Stavudine continues to be widely used in resource poor settings despite its toxicity. Our objective was to determine association between plasma stavudine concentrations and lipoatrophy, concentrations of glucose, lactate and triglycerides. Methods: Participants were enrolled in a cross-s ...
Dopamine Receptor Antagonists Reverse Amphetamine
Dopamine Receptor Antagonists Reverse Amphetamine

... to perform on DRL 10-sec task and then divided into four groups, which received separate types of double injections before the behavioral session. The four groups were the saline control group, the amphetamine alone group, the dopamine antagonist alone group, and the combination amphetamine and dopa ...
Potent inhibition of human cytochrome P450 3A isoforms
Potent inhibition of human cytochrome P450 3A isoforms

... (CBD), and cannabinol (CBN), the three major cannabinoids, on the activity of human cytochrome P450 (CYP) 3A enzymes. Furthermore, we investigated the kinetics and structural requirement for the inhibitory effect of CBD on the CYP3A activity. Main methods: Diltiazem N-demethylase activity of recombi ...
Methadone Poisoning
Methadone Poisoning

... Statistics, medical examiners listed methadone as contributing to 3,849 deaths in 2004, up from 790 in 1999. Approximately 82% of those deaths were listed as accidental and most deaths involved combinations of methadone with other drugs ...
Pharmacokinetics Pallasch, TJ Anes. Progress 35:133
Pharmacokinetics Pallasch, TJ Anes. Progress 35:133

... concentrations from the arterial to the venous blood of an organ from 0 to 1. If one, all drug is removed first pass if 0 non is removed by that organ. ...
GHB - CAP Members
GHB - CAP Members

... GHB and its analogues are abused for their euphoric and calming effects and because some people believe they build muscles and cause weight loss. GHB and its analogues are also misused for their ability to increase libido, suggestibility, passivity, and to cause amnesia (no memory of events while un ...
efficacy of topiramate in migraine prophylaxis
efficacy of topiramate in migraine prophylaxis

... may involve cortical spreading depression and the similar rate of decrease in regional cerebral blood flow observed in migraine patients with aura.1 Traditionally, migraine patients have been treated with valproate or carbamazepine as migraine prophylaxis. Although these agents offer headache relief ...
WHAT ARE THE POSSIBLE SIDE EFFECTS OF DICLOFENAC
WHAT ARE THE POSSIBLE SIDE EFFECTS OF DICLOFENAC

... Aspirin When Diclo (diclofenac sodium) is administered with aspirin, its protein binding is reduced. The clinical significance of this interaction is not known; however, as with other NSAIDs, concomitant administration of diclofenac and aspirin is not generally recommended because of the potential o ...
Pentazocine - e-SAFE
Pentazocine - e-SAFE

... Pentazocine is an effective analgesic post myocardial infarction and may cause a rise in systolic blood pressure in contrast to the hypotensive effect of other opioids. However the associated rise in pulmonary artery pressure, left ventricular end-diastolic pressure and left ventricular minute work ...
Haloperidol and Slot Machine Gambling
Haloperidol and Slot Machine Gambling

... DA release) to variations in monetary reward in PG subjects, strengthening the payoff–bet size correlation in these subjects under the drug. In controls, haloperidol would be expected to promote a within-session decline in reward-related responding as it does in healthy animals (Sanger & Perrault 19 ...
a complimentary source PDF.
a complimentary source PDF.

... We recorded the numbers of participants having one or more CHD events (defined as fatal or non-fatal myocardial infarction or sudden cardiac death but excluding “silent” infarcts) and one or more strokes (haemorrhagic and ischaemic strokes could not be distinguished). We also recorded the numbers of ...
sedative effect of acepromazine micro dose in yintang
sedative effect of acepromazine micro dose in yintang

... study. I hope they may be proud since all the effort they endured to pay and to support my studies merge into what I am and will be as a professional upon completion of my degree. A high school professor once said to me that the world does not give you opportunities but it is you who give yourself o ...
Clenbuterol toxicity: a NSW Poisons Information Centre experience
Clenbuterol toxicity: a NSW Poisons Information Centre experience

... the veterinary product that is being used. However, it was not possible to determine where this product was being sourced. The misuse of this drug poses the secondary risk of accidental poisoning of children. It is often taken in doses far exceeding the safe therapeutic doses in humans, and order-of ...
Queensland Health Presentation Template - Dark Blue
Queensland Health Presentation Template - Dark Blue

...  A synthetic primary opioid agonist and potent narcotic analgesic with rapid onset and short duration. ...
Is the Role of the Small Intestine in First
Is the Role of the Small Intestine in First

... (Bond and Levitt, 1979; Bond et al., 1979). It has also been demonstrated that approximately 60 to 70% of the intestinal blood flow is distributed to the epithelial mucosal cells of cats and rats (Biber et al., 1973; Gore and Bohlen, 1977). Because only part of the intestinal blood flow reaches the ...
The Serotonin Syndrome - Department of Psychiatry
The Serotonin Syndrome - Department of Psychiatry

... autonomic hyperactivity, and neuromuscular abnormalities, but not all of these findings are consistently present in all patients with the disorder (Fig. 1).5,6 Signs of excess serotonin range from tremor and diarrhea in mild cases to delirium, neuromuscular rigidity, and hyperthermia in life-threate ...
The use of injectable nonsteroidal anti
The use of injectable nonsteroidal anti

... or tissue necrosis with IM diclofenac have been documented by several case reports.11-16,18,19 Death as a result has been reported.18,19 Intramuscular diclofenac was shown to result in local reddening and induration in nearly all subjects in comparison with 19.4% in IM piroxicam. 16,25 In addition, ...
Is the Role of the Small Intestine in First
Is the Role of the Small Intestine in First

Inverted U-Shaped Dose-Response Curve of the
Inverted U-Shaped Dose-Response Curve of the

... The purpose of this study was to investigate whether the anxiolytic effect of cannabidiol (CBD) in humans follows the same pattern of an inverted U-shaped dose-effect curve observed in many animal studies. Sixty healthy subjects of both sexes aged between 18 and 35 years were randomly assigned to fi ...


... normalize their distribution, and compared by ANOVA for multiple comparisons (for Phase 1) and by Student's t-test for paired data (for Phases 2 and 3). In Phase 1, four subjects (Nos. 11–14) failed to achieve a 15% fall in FEV1 when the maximum concentration of methacholine was administered and the ...
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Pharmacognosy



Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.
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