Organic Compound proj
... research in the 1950 and 1960s to find a safer, more powerful alternative to aspirin. A team led by Stewart Adams, part of Boots, discovered that carboxylic acid was the agent in aspirin that gave the anti-inflammatory property. Therefore after synthesizing and testing more than 600 compounds create ...
... research in the 1950 and 1960s to find a safer, more powerful alternative to aspirin. A team led by Stewart Adams, part of Boots, discovered that carboxylic acid was the agent in aspirin that gave the anti-inflammatory property. Therefore after synthesizing and testing more than 600 compounds create ...
Nanocarriers for skin delivery of cosmetic antioxidants
... cosmetic formulations from herbal origin to support the health and integrity of the skin and its appendages has been steadily growing because consumers perceive these agents as natural, healthy, nontoxic and full of beneficial effects. Many cosmetic products based on botanical active ingredients pos ...
... cosmetic formulations from herbal origin to support the health and integrity of the skin and its appendages has been steadily growing because consumers perceive these agents as natural, healthy, nontoxic and full of beneficial effects. Many cosmetic products based on botanical active ingredients pos ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
... allyl, the Latin name for garlic. Four years later, Louis Pasteur in Paris showed that allyl could inhibit the growth of bacteria. This was a great discovery because 150 years ago, doctors had nothing to eradicate bacteria. .Garlic was used as a remedy for intestinal disorders, flatulence, worms, re ...
... allyl, the Latin name for garlic. Four years later, Louis Pasteur in Paris showed that allyl could inhibit the growth of bacteria. This was a great discovery because 150 years ago, doctors had nothing to eradicate bacteria. .Garlic was used as a remedy for intestinal disorders, flatulence, worms, re ...
5-Fluorouracil encapsulated alginate beads for the treatment of
... and its evaluation in vitro for developing an improved local delivery system for breast cancer treatment. The factors investigated were the physical appearance of the beads, the amount of 5-FU that could be encapsulated and the mean size of the beads produced. The in vitro release of 5-FU from the b ...
... and its evaluation in vitro for developing an improved local delivery system for breast cancer treatment. The factors investigated were the physical appearance of the beads, the amount of 5-FU that could be encapsulated and the mean size of the beads produced. The in vitro release of 5-FU from the b ...
Methamphetamine Action Plan
... and enhanced mood. The effects of methamphetamine are dose dependent, however, the following effects will occur at greater or lesser levels; euphoria, increased activity and energy levels, dis-inhibition, sense of well-being, increased confidence (often termed ‘bullet-proof’), decreased appetite and ...
... and enhanced mood. The effects of methamphetamine are dose dependent, however, the following effects will occur at greater or lesser levels; euphoria, increased activity and energy levels, dis-inhibition, sense of well-being, increased confidence (often termed ‘bullet-proof’), decreased appetite and ...
Buprenorphine Bluefish sublingual tablet ENG SmPC
... Before stabilization is achieved and opioid tolerance is fully developed, Buprenorphine Bluefish may have major influence on the ability to drive and use machines. ...
... Before stabilization is achieved and opioid tolerance is fully developed, Buprenorphine Bluefish may have major influence on the ability to drive and use machines. ...
An Investigation into the Distribution and Concentration of Drugs of
... Femoral blood is preferable in post-mortem toxicological analysis but may not always be available. Alternative specimens such as cardiac blood, vitreous humour, stomach contents, bile, urine, hair, bone, liver and muscle may be used. However, only limited data are available for the interpretation of ...
... Femoral blood is preferable in post-mortem toxicological analysis but may not always be available. Alternative specimens such as cardiac blood, vitreous humour, stomach contents, bile, urine, hair, bone, liver and muscle may be used. However, only limited data are available for the interpretation of ...
Fentanyl - CannAmm
... There were 665 deaths due to fentanyl overdose, this is one death every 3 days (2007- 2014) There are drastic increases in post modem detection and deaths caused by, or related to, fentanyl: • Alberta: 14 fold increase from 2011 to 2014 (cause or contributor) • British Columbia: 7 fold increase fr ...
... There were 665 deaths due to fentanyl overdose, this is one death every 3 days (2007- 2014) There are drastic increases in post modem detection and deaths caused by, or related to, fentanyl: • Alberta: 14 fold increase from 2011 to 2014 (cause or contributor) • British Columbia: 7 fold increase fr ...
The Science of Gua sha
... Manual therapies like Gua sha may be useful for many conditions but may become essential clinical options particularly for what are called ‘gaps in care’, i.e. when patients cannot or prefer not to take medicines for a problem, or when those medicines fail or are not available. It is well known tha ...
... Manual therapies like Gua sha may be useful for many conditions but may become essential clinical options particularly for what are called ‘gaps in care’, i.e. when patients cannot or prefer not to take medicines for a problem, or when those medicines fail or are not available. It is well known tha ...
Improving patient outcomes - Royal Pharmaceutical Society
... regular medication and is attending a hospital as a day patient for treatment of cancer In England, a NICE Clinical Guideline4 includes best practice advice on how to involve patients in decisions about prescribed medicines and how to support adherence. Interventions that have been investigated to d ...
... regular medication and is attending a hospital as a day patient for treatment of cancer In England, a NICE Clinical Guideline4 includes best practice advice on how to involve patients in decisions about prescribed medicines and how to support adherence. Interventions that have been investigated to d ...
Spreading of Semisolid Formulations: An Update
... final behavior, including their spreading qualities on the substrate. Spreadability can be measured with various types of viscometers and varies according to the formulator’s requirement. In suspension ointments, a logarithmic regression with a negative correlation was found between viscosity and de ...
... final behavior, including their spreading qualities on the substrate. Spreadability can be measured with various types of viscometers and varies according to the formulator’s requirement. In suspension ointments, a logarithmic regression with a negative correlation was found between viscosity and de ...
Unauthorized Research on Cluster Headache
... Perhaps the greatest triumph of unauthorized research on visionary plants and drugs to date is the discovery that small doses of LSD, psilocybin, and LSA (lysergic acid amide) are more effective than any conventional medication in treating the dismal disorder, cluster headache. Five years ago, no on ...
... Perhaps the greatest triumph of unauthorized research on visionary plants and drugs to date is the discovery that small doses of LSD, psilocybin, and LSA (lysergic acid amide) are more effective than any conventional medication in treating the dismal disorder, cluster headache. Five years ago, no on ...
Carisoprodol: an underrecognized drug of abuse in north India
... to our previous study [12] the most common initiator to carisoprodol intake was co-addicts (vs. local chemist), and the most common reason for initiating carisoprodol was for better “kick” (vs. to combat aches). Dose-dependent effect (general wellbeing→ hypomania→confusional state) and craving, tole ...
... to our previous study [12] the most common initiator to carisoprodol intake was co-addicts (vs. local chemist), and the most common reason for initiating carisoprodol was for better “kick” (vs. to combat aches). Dose-dependent effect (general wellbeing→ hypomania→confusional state) and craving, tole ...
Pobierz PDF - Problems of Forensic Sciences
... (tablets, capsules, and powders) seized by the police in narcotics cases. Gas chromatography coupled with mass spectrometry and high performance liquid chromatography were used for identification. Differentiation between two isomers: meta- and parachlorophenylpiperazine, i.e. 1-(3-chlorophenyl)piper ...
... (tablets, capsules, and powders) seized by the police in narcotics cases. Gas chromatography coupled with mass spectrometry and high performance liquid chromatography were used for identification. Differentiation between two isomers: meta- and parachlorophenylpiperazine, i.e. 1-(3-chlorophenyl)piper ...
Behavioral Profiles in Rats Distinguish Among “Ecstasy
... rodents (Pellow & File, 1986). The apparatus consisted of two black Plexiglas open arms (50 ⫻ 10 cm each), two closed arms (50 ⫻ 10 ⫻ 20 cm each) and a central platform (10 ⫻ 10 cm). The maze was elevated 70 cm above the floor. Each animal was placed at the center of the maze, facing one of the clos ...
... rodents (Pellow & File, 1986). The apparatus consisted of two black Plexiglas open arms (50 ⫻ 10 cm each), two closed arms (50 ⫻ 10 ⫻ 20 cm each) and a central platform (10 ⫻ 10 cm). The maze was elevated 70 cm above the floor. Each animal was placed at the center of the maze, facing one of the clos ...
“Robo-Tripping”: Dextromethorphan Abuse and its Anesthetic
... patient’s postoperative pain after septorhinoplasty was easily managed using conventional doses of intravenous followed by oral opioids despite his history of chronic dextromethorphan abuse, suggesting that clinically significant opioid tolerance did not occur. Finally, whether acute dextromethorpha ...
... patient’s postoperative pain after septorhinoplasty was easily managed using conventional doses of intravenous followed by oral opioids despite his history of chronic dextromethorphan abuse, suggesting that clinically significant opioid tolerance did not occur. Finally, whether acute dextromethorpha ...
Pharmacy Compounding: Defining the New Landscape for Safe
... Practitioner’s Prescription Drug Order based on the Practitioner/patient/Pharmacist relationship in the course of professional practice,” adding that “[c]ompounding includes the preparation of limited amounts of Drugs or Devices in anticipation of receiving Prescription Drug Orders based on routine, ...
... Practitioner’s Prescription Drug Order based on the Practitioner/patient/Pharmacist relationship in the course of professional practice,” adding that “[c]ompounding includes the preparation of limited amounts of Drugs or Devices in anticipation of receiving Prescription Drug Orders based on routine, ...
Cp min = 8mg /l
... plasma conc of phenytoin is within the therapeutic range , to prevent any undesirable side effects associated with increased level of phenytoin in plasma). The time to sample phenytoin varies from patient to patient , depending mainly on the disease state the patient is treated from and his clinic ...
... plasma conc of phenytoin is within the therapeutic range , to prevent any undesirable side effects associated with increased level of phenytoin in plasma). The time to sample phenytoin varies from patient to patient , depending mainly on the disease state the patient is treated from and his clinic ...
NIMC User Guide (PDF 2MB) - Australian Commission on Safety
... members of its Health Services Medication Advisory Group (formerly the National Inpatient Medication Chart Oversight Committee) for their significant contribution to this document. Finally, the Commission acknowledges all the users of the NIMC that suggest improvements and participate in audits, all ...
... members of its Health Services Medication Advisory Group (formerly the National Inpatient Medication Chart Oversight Committee) for their significant contribution to this document. Finally, the Commission acknowledges all the users of the NIMC that suggest improvements and participate in audits, all ...
cardiopulmonary, biochemical, and haematological changes after
... values for PCV and Hb returned to the base line and the values for WBC showed a non-significant increase at 24 h. Pooling of circulating blood cells in the spleen and other reservoirs secondary to decreased sympathetic activity could be the reason for a decrease in Hb, PCV, and WBC (8, 17). The decr ...
... values for PCV and Hb returned to the base line and the values for WBC showed a non-significant increase at 24 h. Pooling of circulating blood cells in the spleen and other reservoirs secondary to decreased sympathetic activity could be the reason for a decrease in Hb, PCV, and WBC (8, 17). The decr ...
Steady-state bioequivalence studies of two memantine tablet and
... detection in plasma samples taken at the steady state after 22 days of once-daily dosing. The arithmetic mean (SD) pharmacokinetic parameters in the studies A and B were: AUC0-0τ,ss 768 (141) vs. 727 (99) and 807 (154) vs. 836 (156) ng/ml h, Cmax,ss 37.3 (6.1) vs. 35.2 (4.5) and 39.2 (7.3) vs. 40.6 ...
... detection in plasma samples taken at the steady state after 22 days of once-daily dosing. The arithmetic mean (SD) pharmacokinetic parameters in the studies A and B were: AUC0-0τ,ss 768 (141) vs. 727 (99) and 807 (154) vs. 836 (156) ng/ml h, Cmax,ss 37.3 (6.1) vs. 35.2 (4.5) and 39.2 (7.3) vs. 40.6 ...
Statins Transport, side effects and cytoxicity_Rev2
... with the lactones having a higher metabolic rate. [17,18] While it has been found that rosuvastatin is not significantly metabolized by the CYP enzymes, and is largely excreted unchanged, this situation is complicated by the finding that glucuronidation products of simvastatin acid, cerivastatin aci ...
... with the lactones having a higher metabolic rate. [17,18] While it has been found that rosuvastatin is not significantly metabolized by the CYP enzymes, and is largely excreted unchanged, this situation is complicated by the finding that glucuronidation products of simvastatin acid, cerivastatin aci ...
pharmacology basic principles
... SA of GI tract, mixing of contents, pH differences at different levels; can be destroyed by acid (eg. Some penicillins) and enzymes (eg. Insulin is hydrolysed) and microbial activity INH: can be used from agents that vaporize easily (eg. Amyl nitrite) or can be dispersed in aqueous droplets (eg. Erg ...
... SA of GI tract, mixing of contents, pH differences at different levels; can be destroyed by acid (eg. Some penicillins) and enzymes (eg. Insulin is hydrolysed) and microbial activity INH: can be used from agents that vaporize easily (eg. Amyl nitrite) or can be dispersed in aqueous droplets (eg. Erg ...
Paracetamol - A Review of Three Routes of Administration - e
... A placebo is a pharmacologically inert substance that may have a medical effect based solely on the power of suggestion. This is known as the placebo effect. By comparing drugs to a placebo, the pharmacological effects of the study drug are identified. ...
... A placebo is a pharmacologically inert substance that may have a medical effect based solely on the power of suggestion. This is known as the placebo effect. By comparing drugs to a placebo, the pharmacological effects of the study drug are identified. ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.