Novel Antimicrobial Agents
... the possibility that we may have already exploited most of the broad-spectrum targets essential for bacterial survival in vivo. As academia and government agencies are being urged to become more involved in the process of antibiotic development, the time may be right to begin to exploit more unconve ...
... the possibility that we may have already exploited most of the broad-spectrum targets essential for bacterial survival in vivo. As academia and government agencies are being urged to become more involved in the process of antibiotic development, the time may be right to begin to exploit more unconve ...
Anti-TB - PharmaStreet
... • In the other 25% of active cases, the infection moves from the lungs, causing other kinds of TB, collectively denoted extrapulmonary tuberculosis. This occurs more commonly in immunosuppressed persons and young children. • Extrapulmonary infection sites include the pleura in tuberculosis pleurisy, ...
... • In the other 25% of active cases, the infection moves from the lungs, causing other kinds of TB, collectively denoted extrapulmonary tuberculosis. This occurs more commonly in immunosuppressed persons and young children. • Extrapulmonary infection sites include the pleura in tuberculosis pleurisy, ...
antipyretic activity of methanol extract of acacia leucophloea roxb bark
... Fever, or pyrexia, occurs when the body reaches a temperature above what is considered "average". Bear in mind, however, that this "average" temperature can vary from person to person within certain parameters. It is generally accepted fever exists at a temperature above 37 degrees Celsius when the ...
... Fever, or pyrexia, occurs when the body reaches a temperature above what is considered "average". Bear in mind, however, that this "average" temperature can vary from person to person within certain parameters. It is generally accepted fever exists at a temperature above 37 degrees Celsius when the ...
Clinical Rx Forum Volume 3 Issue 2
... clinicians with an assessment of the risk of teratogenicity of drugs during pregnancy.2 During that time, medications were less commonly used during pregnancy, in part due to the perception that pregnant women were young and healthy and did not require drug therapy. ...
... clinicians with an assessment of the risk of teratogenicity of drugs during pregnancy.2 During that time, medications were less commonly used during pregnancy, in part due to the perception that pregnant women were young and healthy and did not require drug therapy. ...
**z
... Absorption of drugs after oral administration may occur at the various body sites between the mouth and rectum. The higher up a drug is absorbed along the length of the alimentary tract, the more rapid will be its action, a desirable feature in most instances. The differences in the chemical and phy ...
... Absorption of drugs after oral administration may occur at the various body sites between the mouth and rectum. The higher up a drug is absorbed along the length of the alimentary tract, the more rapid will be its action, a desirable feature in most instances. The differences in the chemical and phy ...
3 Perinatal Pharmacology
... the maternal plasma half-life of these drugs is very short, and less drug will ultimately reach the fetus. Conversely, some drugs have long-lived metabolites which can reach the fetus. For example, normeperidine, a metabolite of meperidine, is twice as toxic as the parent compound but only half as a ...
... the maternal plasma half-life of these drugs is very short, and less drug will ultimately reach the fetus. Conversely, some drugs have long-lived metabolites which can reach the fetus. For example, normeperidine, a metabolite of meperidine, is twice as toxic as the parent compound but only half as a ...
... any other drug for that matter, has been responsible for changing the sensation of breathlessness directly, either at the peripheral or central processing level. In other words, the way in which it is perceived independent of changes in the mechanics and control of breathing. It seems more likely th ...
ICCVAM Test Method Evaluation Report: Appendix B2 December 2007 § 314.50
... quired to contain a summary of the ap plication in enough detail that the reader may gain a good general under standing of the data and information in the application, including an under standing of the quantitative aspects of the data. The summary is not required for supplements under § 314.70. ...
... quired to contain a summary of the ap plication in enough detail that the reader may gain a good general under standing of the data and information in the application, including an under standing of the quantitative aspects of the data. The summary is not required for supplements under § 314.70. ...
- Asian Journal of Pharmaceutical Technology and
... Geriatrics is the branch of general medicine concerned with the clinical, preventive, remedial and social aspects of illness in the elderly. Officially the term elderly or geriatrics refers to the person or patient aged 65 years and above. The term elderly is always related to physical incapacity, b ...
... Geriatrics is the branch of general medicine concerned with the clinical, preventive, remedial and social aspects of illness in the elderly. Officially the term elderly or geriatrics refers to the person or patient aged 65 years and above. The term elderly is always related to physical incapacity, b ...
"…in language understandable to the subject…"-
... In its 1995 Information Sheets for Institutional Review Boards and Clinical Investigators, the FDA required that "the information that is given to the subject or representative shall be in language understandable to the subject or the representative," and that "technical and medical terminology shou ...
... In its 1995 Information Sheets for Institutional Review Boards and Clinical Investigators, the FDA required that "the information that is given to the subject or representative shall be in language understandable to the subject or the representative," and that "technical and medical terminology shou ...
New (and emerging) Psychoactive Substances (NPS)
... that are relatively new to recreational drug markets. This term captures all NPS as well as drugs that may not be newly invented, but have recently experienced a resurgence of or increase in use (e.g. 2C-B, DMT). The NPS market has grown rapidly over the past decade and currently encompasses hundred ...
... that are relatively new to recreational drug markets. This term captures all NPS as well as drugs that may not be newly invented, but have recently experienced a resurgence of or increase in use (e.g. 2C-B, DMT). The NPS market has grown rapidly over the past decade and currently encompasses hundred ...
Homeopathic Medicine - Health Vista Home Page
... Homeopathy is 100% compatible with other medications and will not interfere with the effectiveness of other medicines. Other medications may lessen the effects of homeopathy. Many remedies can be affected by strong odors, steroids or caffeine. (www. 1-800homeopathy.com) ...
... Homeopathy is 100% compatible with other medications and will not interfere with the effectiveness of other medicines. Other medications may lessen the effects of homeopathy. Many remedies can be affected by strong odors, steroids or caffeine. (www. 1-800homeopathy.com) ...
Systemic meds and ocular side effects revised
... • Obtain a baseline exam to include a visual field test, color vision test, dilated fundus and optic nerve exam, and visual acuity. • If any visual symptoms occur, patients should discontinue the medication and see an ophthalmologist. ...
... • Obtain a baseline exam to include a visual field test, color vision test, dilated fundus and optic nerve exam, and visual acuity. • If any visual symptoms occur, patients should discontinue the medication and see an ophthalmologist. ...
Use of Medically-Important Antimicrobial Compounds in Animal
... A restricted number of new antibiotics are being developed and becoming available in the supply chain. Only two systemic antibacterial agents have been approved for use in humans by the U.S. FDA since 2008, compared to sixteen that were approved from 1983‐1987. Furthermore, there have been no new ...
... A restricted number of new antibiotics are being developed and becoming available in the supply chain. Only two systemic antibacterial agents have been approved for use in humans by the U.S. FDA since 2008, compared to sixteen that were approved from 1983‐1987. Furthermore, there have been no new ...
Document
... Grandfathering for Step Therapy Most of your existing prescriptions for Branded medications will be exempted from the application of the 4D Step Therapy requirement during the initial conversion period. This grandfathering provision will apply for long-term maintenance Branded medications which are ...
... Grandfathering for Step Therapy Most of your existing prescriptions for Branded medications will be exempted from the application of the 4D Step Therapy requirement during the initial conversion period. This grandfathering provision will apply for long-term maintenance Branded medications which are ...
Etifoxine (Stresam®) for chemotherapy-induced pain?
... consequence of cancer chemotherapy. In particular vinca alkaloids, taxanes and platinum drugs, which are often used for the treatment of solid tumors, cause severe and often dose-limiting painful neuropathies [2]. And the pain generally responds poorly to conventional analgesic treatment. The study ...
... consequence of cancer chemotherapy. In particular vinca alkaloids, taxanes and platinum drugs, which are often used for the treatment of solid tumors, cause severe and often dose-limiting painful neuropathies [2]. And the pain generally responds poorly to conventional analgesic treatment. The study ...
ppt
... Metabolism and Toxicology Finding a substance that shows an effect in vitro does not mean that this is a suitable drug candidate as well. The vast majority of chemical substances undergo biochemical transformations inside the body (metabolisms). Some of these reactions lead to degradation products ( ...
... Metabolism and Toxicology Finding a substance that shows an effect in vitro does not mean that this is a suitable drug candidate as well. The vast majority of chemical substances undergo biochemical transformations inside the body (metabolisms). Some of these reactions lead to degradation products ( ...
Meeting Minutes AAPIFDA Pediatric Exclusivity Provisions of the FDA Modernization
... AAP recommended that a drug be placed on the list using the following criteria: severity, morbidity, mortality of condition for which drug is intended, documented or anticipated use in children, therapeutic index (e.g., risk of adverse effects), presence or absence of equivalent drug already availab ...
... AAP recommended that a drug be placed on the list using the following criteria: severity, morbidity, mortality of condition for which drug is intended, documented or anticipated use in children, therapeutic index (e.g., risk of adverse effects), presence or absence of equivalent drug already availab ...
APPLICATIONS OF METABOLOMICS
... necessarily comprehensive) metabolic changes caused by a biological perturbation. The term 'metabonomics' is rarely used to describe research not directly related to human disease or nutrition. In practice, within the field of human disease research there is still a large degree of overlap in the wa ...
... necessarily comprehensive) metabolic changes caused by a biological perturbation. The term 'metabonomics' is rarely used to describe research not directly related to human disease or nutrition. In practice, within the field of human disease research there is still a large degree of overlap in the wa ...
L11- ANTIPLATELET DRUGS
... have slow onset of action (3 - 5 days). Pro-drugs, they have to be activated in the liver. bound to plasma proteins ...
... have slow onset of action (3 - 5 days). Pro-drugs, they have to be activated in the liver. bound to plasma proteins ...
Toxicological Findings in Cases of Alleged Drug
... interest. The media have adopted the term ‘date-rape’ to describe such cases although many of these cases are clearly not ‘dates’. Toxicology practitioners generally prefer to use the term DFSA instead which can be defined as the use of a drug, noxious substance or chemical agent to facilitate sexua ...
... interest. The media have adopted the term ‘date-rape’ to describe such cases although many of these cases are clearly not ‘dates’. Toxicology practitioners generally prefer to use the term DFSA instead which can be defined as the use of a drug, noxious substance or chemical agent to facilitate sexua ...
Overview of FDA`s Regulatory Framework for PET Drugs
... Non-Critical Quality Attributes • Some product attributes may not be critical to the safety or efficacy of the product, but nevertheless are important in assessing the ongoing quality of the product and to assure that the manufacturing process is in control – Radionuclidic purity (sometimes) – Cert ...
... Non-Critical Quality Attributes • Some product attributes may not be critical to the safety or efficacy of the product, but nevertheless are important in assessing the ongoing quality of the product and to assure that the manufacturing process is in control – Radionuclidic purity (sometimes) – Cert ...
drugs acting on the respiratory system bronchial asthma
... preferable for the relief of acute attack of bronchial asthma. - Administered by inhalation or subcutaneously. Side effects include arrhythmia and worsening of angina pectoris, increase blood pressure, tremors etc. Contraindication: - hypertension, arrhythmia, 2- Ephedrine: compared to epinephrine, ...
... preferable for the relief of acute attack of bronchial asthma. - Administered by inhalation or subcutaneously. Side effects include arrhythmia and worsening of angina pectoris, increase blood pressure, tremors etc. Contraindication: - hypertension, arrhythmia, 2- Ephedrine: compared to epinephrine, ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.