CASSIA TORA ETHANOL INDUCED ULCER Research Article
... Effect of HECT on gastric content, pH, free acidity and total acidity is shown in Table 1. Ethanol caused the accumulation of gastric secretions of 2.16±0.44 ml with pH 2.84±0.25 in Control group. Free acidity and Total acidity in the control group were found to be 70.83±2.38 mEq/l and 151.67±7.03 m ...
... Effect of HECT on gastric content, pH, free acidity and total acidity is shown in Table 1. Ethanol caused the accumulation of gastric secretions of 2.16±0.44 ml with pH 2.84±0.25 in Control group. Free acidity and Total acidity in the control group were found to be 70.83±2.38 mEq/l and 151.67±7.03 m ...
(amphetamine, ephedrine, ecstasy) by LC-MS, GC-MS and CE-MS
... Derivatization of amphetamines for GC In the case of GC the peaks of stimulating amines are very often spread out and distorted ("called tailing") and therefore the derivatization is carried out to improve the shape of the peaks, and reduce unwanted sorption of analytes to the stationary phase. The ...
... Derivatization of amphetamines for GC In the case of GC the peaks of stimulating amines are very often spread out and distorted ("called tailing") and therefore the derivatization is carried out to improve the shape of the peaks, and reduce unwanted sorption of analytes to the stationary phase. The ...
The Essential Medicinal Chemistry of Curcumin
... for therapeutic benefit and is the compound used as a proposed “lead” structure for medicinal chemistry investigations. This Miniperspective will not attempt to address the potential therapeutic effects of even more complex turmeric extracts or preparations thereof but instead focuses on the reported ...
... for therapeutic benefit and is the compound used as a proposed “lead” structure for medicinal chemistry investigations. This Miniperspective will not attempt to address the potential therapeutic effects of even more complex turmeric extracts or preparations thereof but instead focuses on the reported ...
Impact of Ignoring Extraction Ratio When Predicting Drug
... Supplemental material to this article can be found at: http://dmd.aspetjournals.org/content/suppl/2010/08/19/dmd.110.034736.DC1 ...
... Supplemental material to this article can be found at: http://dmd.aspetjournals.org/content/suppl/2010/08/19/dmd.110.034736.DC1 ...
Infant Feeding Guidelines for Drug Using Mothers
... Prolactin appears to stimulate the production and secretion of breast milk, whereas oxytocin stimulates the contraction of the myoepithelial cells that surround breast alveoli. Milk then enters the ducts to be ejected, the “letdown reflex” occurs, and milk is expelled from the breast. Adrenocorticot ...
... Prolactin appears to stimulate the production and secretion of breast milk, whereas oxytocin stimulates the contraction of the myoepithelial cells that surround breast alveoli. Milk then enters the ducts to be ejected, the “letdown reflex” occurs, and milk is expelled from the breast. Adrenocorticot ...
Guidelines for Registration of Fixed
... finished pharmaceutical product (FDC-FPP) may be less than that of separate products given concurrently, and there are simpler logistics of distribution. Improved patient adherence and reduced development of resistance in the case of antimicrobials can be difficult to prove, but may be additional be ...
... finished pharmaceutical product (FDC-FPP) may be less than that of separate products given concurrently, and there are simpler logistics of distribution. Improved patient adherence and reduced development of resistance in the case of antimicrobials can be difficult to prove, but may be additional be ...
Using the Placebo Effect in Clinical Practice Definitions of placebo
... deceptive only when the physician himself knows they are without specific effect but keeps the patient in the dark.” 15 • “Experiments involving humans are now subjected to increasingly careful safeguards for the people at risk, but it will be a long time before the practice of deceiving experimenta ...
... deceptive only when the physician himself knows they are without specific effect but keeps the patient in the dark.” 15 • “Experiments involving humans are now subjected to increasingly careful safeguards for the people at risk, but it will be a long time before the practice of deceiving experimenta ...
An Evaluation of Drugs Used in the Control of Stressful Stimuli in
... of drugs in the mitigation or prevention of stress in domestic, wild and laboratory animals. For ethical and other reasons, such studies in humans are not conducted. However, the results of these studies may find applications in humans. The choice of these drugs as antistressors is either empirical, ...
... of drugs in the mitigation or prevention of stress in domestic, wild and laboratory animals. For ethical and other reasons, such studies in humans are not conducted. However, the results of these studies may find applications in humans. The choice of these drugs as antistressors is either empirical, ...
Methysergide Potentiates the Hyperactivity Produced by MDMA in
... hydrochloride (provided by the National Institute on Drug Abuse) and methysergide maleate were dissolved in saline ...
... hydrochloride (provided by the National Institute on Drug Abuse) and methysergide maleate were dissolved in saline ...
prediction of human hepatic clearance from in vivo animal
... efficacy and safety profiles of the drug. Safe and efficient drug candidates must therefore be selected before clinical trials. On the other hand, there is growing awareness of the key roles that pharmacokinetics and drug metabolism play as determinants of in vivo action. In these situations, early ...
... efficacy and safety profiles of the drug. Safe and efficient drug candidates must therefore be selected before clinical trials. On the other hand, there is growing awareness of the key roles that pharmacokinetics and drug metabolism play as determinants of in vivo action. In these situations, early ...
DRI® Barbiturate Assay - Thermo Fisher Scientific
... The Mandatory Guidelines for Federal Workplace Drug Testing Programs; Final Guidelines recommends that specimens that do not receive an initial test within 7 days of arrival in the laboratory should be placed into secure refrigeration units. Samples within a pH range of 3 to 11 are suitable for test ...
... The Mandatory Guidelines for Federal Workplace Drug Testing Programs; Final Guidelines recommends that specimens that do not receive an initial test within 7 days of arrival in the laboratory should be placed into secure refrigeration units. Samples within a pH range of 3 to 11 are suitable for test ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) ISSN: 2278-3008.
... mice capable of remaining on to top for 3min or more, in three successive trials were selected for the study. The selected animals were divided into 3 groups (n=6). Methanolic extract of solanum pubescens at the dose of 300mg/kg were injected intra peritoneally into group I, group II, received contr ...
... mice capable of remaining on to top for 3min or more, in three successive trials were selected for the study. The selected animals were divided into 3 groups (n=6). Methanolic extract of solanum pubescens at the dose of 300mg/kg were injected intra peritoneally into group I, group II, received contr ...
GAO WOMEN’S HEALTH Women Sufficiently Represented in New
... safety, and that analyses of sex differences should be reported in new drug applications. The 1998 regulation has the force of law, but it is less specific than the guidance. The regulation requires that safety and efficacy data already collected be presented separately for men and women in new drug ...
... safety, and that analyses of sex differences should be reported in new drug applications. The 1998 regulation has the force of law, but it is less specific than the guidance. The regulation requires that safety and efficacy data already collected be presented separately for men and women in new drug ...
Sikh
... • Marijuana produces mild analgesic effects (pain relief), but it is not related pharmacologically to opiates like drugs. • Marijuana produces hallucinations at high doses, but its structure does not resemble LSD or any other drug formally categorized as hallucinogen. ...
... • Marijuana produces mild analgesic effects (pain relief), but it is not related pharmacologically to opiates like drugs. • Marijuana produces hallucinations at high doses, but its structure does not resemble LSD or any other drug formally categorized as hallucinogen. ...
Archives of Medical Research
... hydrogen peroxide is transformed by catalase into water. When an excessive quantity of superoxide radical is produced, it can induce severe tissue damage (17). Several experimental models have been used in order to study the ability of some drugs to eliminate free radicals (13). Among the most frequ ...
... hydrogen peroxide is transformed by catalase into water. When an excessive quantity of superoxide radical is produced, it can induce severe tissue damage (17). Several experimental models have been used in order to study the ability of some drugs to eliminate free radicals (13). Among the most frequ ...
How to Deliver Respiratory Treatments to Neonates by
... reducing signs of inflammation between systemically administered corticosteroids and traditional methods.8 In human medicine, inhaled corticosteroids have been shown to be highly effective in controlling inflammatory conditions. Furthermore, all act by binding a common glucocorticoid receptor, but the ...
... reducing signs of inflammation between systemically administered corticosteroids and traditional methods.8 In human medicine, inhaled corticosteroids have been shown to be highly effective in controlling inflammatory conditions. Furthermore, all act by binding a common glucocorticoid receptor, but the ...
Anti-inflammatory, Antinociceptive, Antipyretic and
... Recent ongoing research is directed to find natural products that possess therapeutic effects and devoid of side effects. Inflammation, analgesia, pyrexia and gastric disturbances are associated with several pathological conditions. The present study aimed to investigate the anti-inflammatory, antin ...
... Recent ongoing research is directed to find natural products that possess therapeutic effects and devoid of side effects. Inflammation, analgesia, pyrexia and gastric disturbances are associated with several pathological conditions. The present study aimed to investigate the anti-inflammatory, antin ...
Development and validation of an in vitro–in vivo correlation for
... 0.1 M HCl and pH 6.8 phosphate buffer dissolution media at both 50 and 100 rpm. • A good linear regression relationship was observed between the dissolution testing using pH 6.8 phosphate buffer at 50 rpm and the percents absorbed for the combined data of the two dosage forms ...
... 0.1 M HCl and pH 6.8 phosphate buffer dissolution media at both 50 and 100 rpm. • A good linear regression relationship was observed between the dissolution testing using pH 6.8 phosphate buffer at 50 rpm and the percents absorbed for the combined data of the two dosage forms ...
The Thai Professional Award
... Big Risk for Pharmaceutical Industry It can take as long as 15-20 years and cost as much as $800 million to develop and market a new drug. ...
... Big Risk for Pharmaceutical Industry It can take as long as 15-20 years and cost as much as $800 million to develop and market a new drug. ...
An anti-epileptic and anti-Parkinson`s disease agent zonisamide
... other causes, as well as for treating neuromuscular disorders in humans. This work was published online in PLOS ONE on November 16, 2015. Research Background For peripheral neuropathies due to injuries and some other causes, local administrations of the nerve growth factor (NGF), brain-derived neuro ...
... other causes, as well as for treating neuromuscular disorders in humans. This work was published online in PLOS ONE on November 16, 2015. Research Background For peripheral neuropathies due to injuries and some other causes, local administrations of the nerve growth factor (NGF), brain-derived neuro ...
Rational Drug Design Approach for Overcoming Drug Resistance
... Department of Biomolecular Sciences, UMIST, Manchester M60 1QD, U.K., School of Biological Sciences, University of Manchester, Manchester M13 9PT, U.K., National Science and Technology Development Agency, Rama VI Road, Bangkok 10400, Thailand, and Department of Biochemistry, Faculty of Science, Mahi ...
... Department of Biomolecular Sciences, UMIST, Manchester M60 1QD, U.K., School of Biological Sciences, University of Manchester, Manchester M13 9PT, U.K., National Science and Technology Development Agency, Rama VI Road, Bangkok 10400, Thailand, and Department of Biochemistry, Faculty of Science, Mahi ...
A comparative bioequivalence study of two prolonged
... to extensive presystemic metabolism in the liver. However, due to the large therapeutic window and common individual dose adjustments, these differences among subjects are not clinically relevant. Peak plasma concentrations are achieved within 2 to 3 hours after drug administration [4,7], and bioava ...
... to extensive presystemic metabolism in the liver. However, due to the large therapeutic window and common individual dose adjustments, these differences among subjects are not clinically relevant. Peak plasma concentrations are achieved within 2 to 3 hours after drug administration [4,7], and bioava ...
1 Revised manuscript Published in Colloids and Surfaces A
... 600 °C to avoid possible contamination presenting surface activity. Doubly distilled water checked by its conductivity (<5 mS) and surface tension (>72.0 mNm-1 at 23 ± 0.5 °C) was the subphase in the Langmuir balance experiments. 2.2 Preparation of nanoparticles and drug encapsulation PLGA nanoparti ...
... 600 °C to avoid possible contamination presenting surface activity. Doubly distilled water checked by its conductivity (<5 mS) and surface tension (>72.0 mNm-1 at 23 ± 0.5 °C) was the subphase in the Langmuir balance experiments. 2.2 Preparation of nanoparticles and drug encapsulation PLGA nanoparti ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.