Gene Section RAP1B (RAP1B, member of RAS oncogene family)
... Rap1 is bound to membranes. In many cell types, it is found in a perinuclear compartment overlapping the Golgi. Rap1 proteins (A and B) are phosphorylated near the C-ter by cAMP-dependent protein kinase. This results in translocation of part of the Rap1 pool to the cytosol. ...
... Rap1 is bound to membranes. In many cell types, it is found in a perinuclear compartment overlapping the Golgi. Rap1 proteins (A and B) are phosphorylated near the C-ter by cAMP-dependent protein kinase. This results in translocation of part of the Rap1 pool to the cytosol. ...
p53 gene mutation: software and database
... types of cancer. As of September 1995, this database contains over 4200 mutations. This substantial increase since our previous report can enable epidemiological analyses which were not previously possible. In order to capture all these new data, the software permitting analysis has been improved. T ...
... types of cancer. As of September 1995, this database contains over 4200 mutations. This substantial increase since our previous report can enable epidemiological analyses which were not previously possible. In order to capture all these new data, the software permitting analysis has been improved. T ...
Replication Protein A (RPA1a) Is Required for Meiotic and Somatic
... DNA double-strand break (DSB) repair is particularly important in maintaining the integrity of genome among individuals and shuffling genetic information among population, because DSBs are generated not only in meiotic cells but also from the action of certain endogenous or exogenous DNA-damaging ag ...
... DNA double-strand break (DSB) repair is particularly important in maintaining the integrity of genome among individuals and shuffling genetic information among population, because DSBs are generated not only in meiotic cells but also from the action of certain endogenous or exogenous DNA-damaging ag ...
C485 Exam I
... reaction used to activate and form this tag. Comment on the energy requirements for this reaction. Why is this necessary? See figure 23.3. This reaction requires the equivalent of 2 ATP cleavages (ATP goes to AMP and 2Pi) because you are making a thioester bond, which is energetically higher in ener ...
... reaction used to activate and form this tag. Comment on the energy requirements for this reaction. Why is this necessary? See figure 23.3. This reaction requires the equivalent of 2 ATP cleavages (ATP goes to AMP and 2Pi) because you are making a thioester bond, which is energetically higher in ener ...
C274/SQP363 NATIONAL QUALIFICATIONS Biology
... 4. The diagram below represents part of a protein molecule. amino acid ...
... 4. The diagram below represents part of a protein molecule. amino acid ...
11.2 Meiosis
... 1. Homologous chromosomes separate & are pulled to opposite ends 2. Chromosomes do not separate at centromeres D. Telophase I 1. The two new cells contain half the number of chromosomes 2. Called reduction division III. Meiosis II A. Identical to stages of mitosis with a few exceptions 1. Chromosome ...
... 1. Homologous chromosomes separate & are pulled to opposite ends 2. Chromosomes do not separate at centromeres D. Telophase I 1. The two new cells contain half the number of chromosomes 2. Called reduction division III. Meiosis II A. Identical to stages of mitosis with a few exceptions 1. Chromosome ...
Course Outline - Athol Murray College of Notre Dame
... 2.1 Explain how carbon-based molecules interact with each other through hydrogen bonding. 2.2 Compare mono-, di-, and polysaccharides and then provide examples of their usefulness to a living system. 2.3 Describe the relationship between fatty acids and fats by providing examples to illustrate when ...
... 2.1 Explain how carbon-based molecules interact with each other through hydrogen bonding. 2.2 Compare mono-, di-, and polysaccharides and then provide examples of their usefulness to a living system. 2.3 Describe the relationship between fatty acids and fats by providing examples to illustrate when ...
Journal of Biotechnology
... The 37.2 kb bmy gene cluster is an insertion within the FZB42 genome, which is separated by only 25 kb from the fengycin gene cluster. It comprises four genes (bmyD, bmyA, bmyB and bmyC) without orthologues in B. subtilis 168 (Fig. 3). The first gene bmyD encodes a putative malonyl coenzyme A transac ...
... The 37.2 kb bmy gene cluster is an insertion within the FZB42 genome, which is separated by only 25 kb from the fengycin gene cluster. It comprises four genes (bmyD, bmyA, bmyB and bmyC) without orthologues in B. subtilis 168 (Fig. 3). The first gene bmyD encodes a putative malonyl coenzyme A transac ...
Protein Family Classification with Neural Networks
... it achieved the best results of our models. It had slightly better performance than the LSTM and biLSTM models, but this might be due to the particular instantiation of hyperparameters. However, the GRU model was training 10% faster than the LSTM models. For the convolution networks, we saw a gain f ...
... it achieved the best results of our models. It had slightly better performance than the LSTM and biLSTM models, but this might be due to the particular instantiation of hyperparameters. However, the GRU model was training 10% faster than the LSTM models. For the convolution networks, we saw a gain f ...
Data Correlation Details: Enrichment Analysis
... be seen by looking at a single, existing experiment. These results may be interesting in themselves (eg, associations between different treatment factors, or between a treatment and an existing known pathway or protein family), or may be used to guide further research and experimentation.1,2 The pri ...
... be seen by looking at a single, existing experiment. These results may be interesting in themselves (eg, associations between different treatment factors, or between a treatment and an existing known pathway or protein family), or may be used to guide further research and experimentation.1,2 The pri ...
Y genetic variation and phenotypic diversity in health and disease
... A male-biased sexual dimorphism exists in the incidence and prevalence of many cardiovascular diseases [38]. Blood pressure is a risk factor associated with cardiovascular disease, and rodent models of hypertension have identified ChrY as a contributor to hypertension in males. A rat model was used ...
... A male-biased sexual dimorphism exists in the incidence and prevalence of many cardiovascular diseases [38]. Blood pressure is a risk factor associated with cardiovascular disease, and rodent models of hypertension have identified ChrY as a contributor to hypertension in males. A rat model was used ...
In Vitro Translation Systems – Protein expression
... The 1-Step Human High-Yield IVT Kits are cell-free protein expression systems that provide all of the essential components required for transcription and translation. The kits are optimized with Accessory Proteins and Reaction Mixes that support protein synthesis using a DNA template. The advantages ...
... The 1-Step Human High-Yield IVT Kits are cell-free protein expression systems that provide all of the essential components required for transcription and translation. The kits are optimized with Accessory Proteins and Reaction Mixes that support protein synthesis using a DNA template. The advantages ...
Document
... see that over time the percentage of tumor free mice go down. Ras is another important oncogene. The same thing happens when you put this into a transgenic mouse, but it happens more quickly than Myc. If you put the two of them together in the same mouse the rate increases again. They are able to to ...
... see that over time the percentage of tumor free mice go down. Ras is another important oncogene. The same thing happens when you put this into a transgenic mouse, but it happens more quickly than Myc. If you put the two of them together in the same mouse the rate increases again. They are able to to ...
Phenotypes in the Mouse Genome Database: functional screens to
... • alleles of different genes can interact to produce unique phenotypes • genetic background can greatly influence mutant phenotypes • imprinted genes/alleles influence phenotype ...
... • alleles of different genes can interact to produce unique phenotypes • genetic background can greatly influence mutant phenotypes • imprinted genes/alleles influence phenotype ...
Myriad myPath® Melanoma Technical Specifications
... This gene expression signature is intended for the in vitro analysis of melanocytic neoplasms to aid in the diagnosis of the lesion as benign or malignant. This is an adjunctive assay and should be used in conjunction with clinical data and histopathological features. Summary and Explanation Melanom ...
... This gene expression signature is intended for the in vitro analysis of melanocytic neoplasms to aid in the diagnosis of the lesion as benign or malignant. This is an adjunctive assay and should be used in conjunction with clinical data and histopathological features. Summary and Explanation Melanom ...
Classification and Diagnostic Prediction of Cancers using
... Feature extraction was performed in a model dependent way due to relatively few samples. This was achieved by monitoring the sensitivity of classification to a change in the expression level of each gene, using the 3750 previously calibrated models. ...
... Feature extraction was performed in a model dependent way due to relatively few samples. This was achieved by monitoring the sensitivity of classification to a change in the expression level of each gene, using the 3750 previously calibrated models. ...
(Sex Linked Traits) and 5 (Pedigree Charts)
... sexlinked trait a gene carried on the sex chromosome that is present in both sexes; one copy in one sex, two copies in the other ...
... sexlinked trait a gene carried on the sex chromosome that is present in both sexes; one copy in one sex, two copies in the other ...
Genetic Counseling and Breeding Management of
... In Bilye's pedigree, an inbreeding coefficient based on four generations computes to 7.81%. This is not significantly different from the estimate based on the first-cousin mating alone. Inbreeding coefficients based on increasing numbers of generations are as follows: five generations, 13.34%; six g ...
... In Bilye's pedigree, an inbreeding coefficient based on four generations computes to 7.81%. This is not significantly different from the estimate based on the first-cousin mating alone. Inbreeding coefficients based on increasing numbers of generations are as follows: five generations, 13.34%; six g ...
Chromosome Number
... If the three genetic loci occur in close sequence on the chromosome - Crossing over very UNlikely to occur between loci - Allelic patterns of grandparents will likely to be preserved in parental gametes ...
... If the three genetic loci occur in close sequence on the chromosome - Crossing over very UNlikely to occur between loci - Allelic patterns of grandparents will likely to be preserved in parental gametes ...
Case study I: DNA copy number changes
... Copy number variations (CNVs) Approx. 12% of the human genome consists of copy number variations ...
... Copy number variations (CNVs) Approx. 12% of the human genome consists of copy number variations ...
Educator's Resource Guide 4226 Biology 1 s 4-5
... ▶ Where two or more alleles for a gene exist, some may be dominant and others recessive. ▶ In sexually reproducing organisms, offspring receive a copy of each gene from each parent. The alleles segregate when forming gametes. ▶ Alleles for different genes usually segregate independently. ...
... ▶ Where two or more alleles for a gene exist, some may be dominant and others recessive. ▶ In sexually reproducing organisms, offspring receive a copy of each gene from each parent. The alleles segregate when forming gametes. ▶ Alleles for different genes usually segregate independently. ...