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The Suprachiasmatic Nucleus Gets Split: Why Does Cortisol
The Suprachiasmatic Nucleus Gets Split: Why Does Cortisol

... sensitivity to ACTH (3). Adrenal sensitivity is modulated by splanchnic neural activity (4, 5). Taken together, these findings have led to the hypothesis that rhythms in adrenal secretion of glucocorticoids are regulated by not only pituitary ACTH but also sympathetic adrenal innervation (6, 7). In ...
The Role Of Preclinical Models In The Development Of Psychotropic
The Role Of Preclinical Models In The Development Of Psychotropic

... cognitive fragmentation. The hypothetical construct of attentional filtering has been defined operationally and explored in multiple paradigms and in both human and animal studies. For example, numerous studies of schizophrenia patients have demonstrated deficits in behavioral habituation, which is ...
Movement Disorders Induced by Gastrointestinal Drugs: Two
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... initial positive benefits, in the absence of adverse effects, the nizatidine dosage was increased to 300 mg twice a day. Within 4 days after this dosage increase, the patient started pacing and could not sit still. Mild Parkinsonism was also present. Concern for these extrapyramidal symptoms led to ...
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ANTI-ARRHYTHMIC DRUGS

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Phosholipase C-Related Inactive Protein Is Involved in Trafficking of
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Drug-Induced Hyperandrogenism

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this PDF file

... Category A: A risk to the fetus has not been demonstrated in controlled studies in women in the first trimester and there is no evidence of risk in later trimester and the possibility of fetal harm appears remote e.g. cyproheptadine [7]. Category B: A fetal risk has not been demonstrated in animal st ...
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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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