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C) Familial Hypercholesterolaemia
C) Familial Hypercholesterolaemia

... Statins come in tablet form and work by slowing down the production of cholesterol in the liver, which is where most of the body’s cholesterol is made. Statins are thoroughly tested and very effective at lowering cholesterol, LDL in particular. They are generally well tolerated, and reassuringly hav ...
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fulltext

... and SNr. The GABA neurons of the GPi are tonically active, hence continuously inhibiting the thalamus from activating the frontal cortex from initiating movement. However, with a decision to move, the striatal MSNs becomes activated by glutamatergic projections from the cortex and DArgic projections ...
Authors’ Reply to Whitlock: Perispinal Etanercept
Authors’ Reply to Whitlock: Perispinal Etanercept

... or clinical investigation of tumor necrosis factor (TNF) mechanisms involving the brain, i.e. in neuroinflammation research [1–16]. One of the aims of our 2014 review was to bring together the increasing scientific evidence, from multiple fields of investigation and multiple academic centers that su ...
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Medicare JH Local Coverage Article A52018

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Neuropsychopharmacology

Neuropsychopharmacology, an interdisciplinary science related to psychopharmacology (how drugs affect the mind) and fundamental neuroscience, is the study of the neural mechanisms that drugs act upon to influence behavior. It entails research of mechanisms of neuropathology, pharmacodynamics (drug action), psychiatric illness, and states of consciousness. These studies are instigated at the detailed level involving neurotransmission/receptor activity, bio-chemical processes, and neural circuitry. Neuropsychopharmacology supersedes psychopharmacology in the areas of ""how"" and ""why"", and additionally addresses other issues of brain function. Accordingly, the clinical aspect of the field includes psychiatric (psychoactive) as well as neurologic (non-psychoactive) pharmacology-based treatments.Developments in neuropsychopharmacology may directly impact the studies of anxiety disorders, affective disorders, psychotic disorders, degenerative disorders, eating behavior, and sleep behavior.The way fundamental processes of the brain are being discovered is creating a field on par with other “hard sciences” such as chemistry, biology, and physics, so that eventually it may be possible to repair mental illness with ultimate precision. An analogy can be drawn between the brain and an electronic device: neuropsychopharmacology is tantamount to revealing not only the schematic diagram, but the individual components, and every principle of their operation. The bank of amassed detail and complexity involved is huge; mere samples of some of the details are given in this article.
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