The Oxidosqualene Cyclase from the Oomycete Saprolegnia
... is significantly truncated (Warrilow et al., 2014). Both gene products possess the Y,N,V triad that is believed to determine enzyme specificity. It is, however, unclear if both proteins are catalytically active enzymes, as there is limited information on the other protein features required for LAS a ...
... is significantly truncated (Warrilow et al., 2014). Both gene products possess the Y,N,V triad that is believed to determine enzyme specificity. It is, however, unclear if both proteins are catalytically active enzymes, as there is limited information on the other protein features required for LAS a ...
Introduction to Bioinformatics 2. Biology Background
... The Expect value (E) is a parameter that describes the number of hits one can "expect" to see just by chance when searching a database of a particular size. It decreases exponentially with the Score (S) that is assigned to a match between two sequences. Essentially, the E value describes the random ...
... The Expect value (E) is a parameter that describes the number of hits one can "expect" to see just by chance when searching a database of a particular size. It decreases exponentially with the Score (S) that is assigned to a match between two sequences. Essentially, the E value describes the random ...
A-level Biology Mark scheme Unit 05
... AQA retains the copyright on all its publications. However, registered schools/colleges for AQA are permitted to copy material from this booklet for their own internal use, with the following important exception: AQA cannot give permission to schools/colleges to photocopy any material that is acknow ...
... AQA retains the copyright on all its publications. However, registered schools/colleges for AQA are permitted to copy material from this booklet for their own internal use, with the following important exception: AQA cannot give permission to schools/colleges to photocopy any material that is acknow ...
Ch. 25
... • Oxidation is the removal of electrons from a molecule and results in a decrease in the energy content of the molecule. Because most biological oxidations involve the loss of hydrogen atoms, they are called dehydrogenation reactions. • When a substance is oxidized, the liberated hydrogen atoms do n ...
... • Oxidation is the removal of electrons from a molecule and results in a decrease in the energy content of the molecule. Because most biological oxidations involve the loss of hydrogen atoms, they are called dehydrogenation reactions. • When a substance is oxidized, the liberated hydrogen atoms do n ...
(RYR1) in a malignant hyperthermia Italian family
... residues 1641-243716 and 1635-263617 are essential for the conduction properties of the calcium release channel. Therefore, the novel mutation described here lies in a portion of the molecule crucial for its function. The identification of novel mutations in the RYR1 gene associated with the MHS phe ...
... residues 1641-243716 and 1635-263617 are essential for the conduction properties of the calcium release channel. Therefore, the novel mutation described here lies in a portion of the molecule crucial for its function. The identification of novel mutations in the RYR1 gene associated with the MHS phe ...
Lecture 12 Proteins Classification of protein Proteins are classified
... They are insoluble in neutral solvents. Coagulated proteins Coagulated proteins are insoluble products formed by the action of heat or alcohol on natural proteins e.g., cooked meat and cooked albumin. Secondary-derived proteins These proteins are formed in the progressive hydrolytic cleavage ...
... They are insoluble in neutral solvents. Coagulated proteins Coagulated proteins are insoluble products formed by the action of heat or alcohol on natural proteins e.g., cooked meat and cooked albumin. Secondary-derived proteins These proteins are formed in the progressive hydrolytic cleavage ...
Supplementary Figure 1
... evolution; therefore the branch lengths correspond to amino acid substitutions per time unit. Evidently, UbS27a domains are less conserved than ribosomal S27a domains or homologs to SUMO1, despite the presence of a hypervariable loop at the N-terminus of SUMO1. Particularly indicative of a high rate ...
... evolution; therefore the branch lengths correspond to amino acid substitutions per time unit. Evidently, UbS27a domains are less conserved than ribosomal S27a domains or homologs to SUMO1, despite the presence of a hypervariable loop at the N-terminus of SUMO1. Particularly indicative of a high rate ...
... biochemical, cytogenetic and molecular markers are used to unveil genetic diversity in crop plants [7]. Diversity studies using genetic markers reveal polymorphisms and provide insights about crop genetic relationships and phylogenetic origins. Morphological markers rely on phenotypic variations whi ...
Krebs Cycle
... • Oxidation is the removal of electrons from a molecule and results in a decrease in the energy content of the molecule. Because most biological oxidations involve the loss of hydrogen atoms, they are called dehydrogenation reactions. • When a substance is oxidized, the liberated hydrogen atoms do n ...
... • Oxidation is the removal of electrons from a molecule and results in a decrease in the energy content of the molecule. Because most biological oxidations involve the loss of hydrogen atoms, they are called dehydrogenation reactions. • When a substance is oxidized, the liberated hydrogen atoms do n ...
Identification of eight novel coagulation factor XIII subunit A
... residues that were found to be mutated in our patient cohort. Detailed views of the local molecular environments of each of the individual wild-type residues at each of these positions are shown in Figure 2(A-F). Tyr167 is situated in the !-sandwich domain. It is the first amino acid of the short !- ...
... residues that were found to be mutated in our patient cohort. Detailed views of the local molecular environments of each of the individual wild-type residues at each of these positions are shown in Figure 2(A-F). Tyr167 is situated in the !-sandwich domain. It is the first amino acid of the short !- ...
Genetic Algorithms: A Tutorial
... Obviously this depends on the problem! GA’s often encode solutions as fixed length “bitstrings” (e.g. 101110, 111111, 000101) Each bit represents some aspect of the proposed solution to the problem For GA’s to work, we need to be able to “test” any string and get a “score” indicating how “good” that ...
... Obviously this depends on the problem! GA’s often encode solutions as fixed length “bitstrings” (e.g. 101110, 111111, 000101) Each bit represents some aspect of the proposed solution to the problem For GA’s to work, we need to be able to “test” any string and get a “score” indicating how “good” that ...
Chapter 26 Nutrition and Metabolism *Lecture PowerPoint
... • Net protein utilization—the percentage of amino acids in a protein that the human body uses – 70% to 90% of animal proteins – 40% to 70% of plant proteins • 14 oz of rice and beans provides same amount of usable protein as 4 oz hamburger ...
... • Net protein utilization—the percentage of amino acids in a protein that the human body uses – 70% to 90% of animal proteins – 40% to 70% of plant proteins • 14 oz of rice and beans provides same amount of usable protein as 4 oz hamburger ...
HSAN1 - Deater Foundation, Inc.
... Sensory neurons carry information about the environment, such as pressure, touch, temperature, and pain to the spinal cord. From there, signals get carried to the brain to tell the body what sensation is being detected. ...
... Sensory neurons carry information about the environment, such as pressure, touch, temperature, and pain to the spinal cord. From there, signals get carried to the brain to tell the body what sensation is being detected. ...
annotated slides Power Point
... transferase or translocator activity are related to disease state • Symptons include muscle cramping during exercise, severe weakness and death. • Affects muscles, kidney, and heart tissues. • Muscle weakness related to importance of fatty acids as long term energy source • People with this disease ...
... transferase or translocator activity are related to disease state • Symptons include muscle cramping during exercise, severe weakness and death. • Affects muscles, kidney, and heart tissues. • Muscle weakness related to importance of fatty acids as long term energy source • People with this disease ...
Secondary metabolism is a term for pathways and products
... are found across all species within broad phylogenetic groupings, and are produced using the same pathway (or nearly the same pathway) in all these species. Secondary metabolites, by contrast, are often species-specific (or found in only a small set of species in a narrow phylogenetic group), and wi ...
... are found across all species within broad phylogenetic groupings, and are produced using the same pathway (or nearly the same pathway) in all these species. Secondary metabolites, by contrast, are often species-specific (or found in only a small set of species in a narrow phylogenetic group), and wi ...
Molecular Aspects of Hereditary Sensory
... Sensory neurons carry information about the environment, such as pressure, touch, temperature, and pain to the spinal cord. From there, signals get carried to the brain to tell the body what sensation is being detected. ...
... Sensory neurons carry information about the environment, such as pressure, touch, temperature, and pain to the spinal cord. From there, signals get carried to the brain to tell the body what sensation is being detected. ...
Biology and computers
... Short stretches of 5 hydrophilic residues often indicate loop or random coil regions (not essential for structure) and therefore gap penalties are reduced reduced for such stretches. Gap penalties for closely related sequences are lowered compared to more distantly related sequences (“once a gap alw ...
... Short stretches of 5 hydrophilic residues often indicate loop or random coil regions (not essential for structure) and therefore gap penalties are reduced reduced for such stretches. Gap penalties for closely related sequences are lowered compared to more distantly related sequences (“once a gap alw ...
Anne Ye - A Critical Review of Computational Protein Design Strategies: Progress, Limitations, and Improvements
... that cannot be present in the global minimum energy conformation (GMEC). Briefly, for each amino acid at a given position, two rotamers, or side chain conformations, are compared with respect to the sum of the side chain-backbone energy (for that particular amino acid) and the minimum side chain-sid ...
... that cannot be present in the global minimum energy conformation (GMEC). Briefly, for each amino acid at a given position, two rotamers, or side chain conformations, are compared with respect to the sum of the side chain-backbone energy (for that particular amino acid) and the minimum side chain-sid ...
Medical Genetics: An Overview
... numbers of mtDNA molecules in each mitochondrion as well. Each molecule of the mitochondrial genome consists exclusively of 37 genes. Though it constitutes very tiny fraction of the whole genome, mtDNA is indispensable for life because it codes, with other nuclear genes, for proteins that mediate AT ...
... numbers of mtDNA molecules in each mitochondrion as well. Each molecule of the mitochondrial genome consists exclusively of 37 genes. Though it constitutes very tiny fraction of the whole genome, mtDNA is indispensable for life because it codes, with other nuclear genes, for proteins that mediate AT ...
BioPerf: A Benchmark Suite to Evaluate High-Performance
... To allow computer architecture researchers to explore and evaluate their designs on these emerging applications, we developed BioPerf, a suite of representative applications assembled from the computational biology community, where the codes are carefully selected to span a breadth of algorithms and ...
... To allow computer architecture researchers to explore and evaluate their designs on these emerging applications, we developed BioPerf, a suite of representative applications assembled from the computational biology community, where the codes are carefully selected to span a breadth of algorithms and ...
Lecture3_HomologyAndAlignment2014_10sept
... • Proteins are composed of twenty amino acids, and physical-chemical properties of individual amino acids vary considerably. • can be based on any property of amino acids: size, polarity, charge, hydrophobicity. • Evolutionary substitution matrices – empirically derived by assessment of frequencies ...
... • Proteins are composed of twenty amino acids, and physical-chemical properties of individual amino acids vary considerably. • can be based on any property of amino acids: size, polarity, charge, hydrophobicity. • Evolutionary substitution matrices – empirically derived by assessment of frequencies ...
Amino Acid Composition in Fillets of Mirror Crossbreds Common
... crossing). These breeds were the Hungarian mirror carp (M2) for pure breed production, Hungarian mirror line (L15), the Israeli breed (DOR70) and the Northern mirror carp (M72). The scaly hybrid of the Ropsha (ROP) and the Tataj (TAT) carp was used as a control. The fish were reared under standard c ...
... crossing). These breeds were the Hungarian mirror carp (M2) for pure breed production, Hungarian mirror line (L15), the Israeli breed (DOR70) and the Northern mirror carp (M72). The scaly hybrid of the Ropsha (ROP) and the Tataj (TAT) carp was used as a control. The fish were reared under standard c ...
1 - Medical Mastermind Community
... Fatty acid synthesis occurs within the cytosol, while fatty acid degradation occurs within the mitochondrial matrix. Three carbon units are added as malonyl-CoA in fatty acid synthesis, while two carbon units are liberated as acetyl-CoA in fatty acid degradation. NADPH is the electron donor in fatty ...
... Fatty acid synthesis occurs within the cytosol, while fatty acid degradation occurs within the mitochondrial matrix. Three carbon units are added as malonyl-CoA in fatty acid synthesis, while two carbon units are liberated as acetyl-CoA in fatty acid degradation. NADPH is the electron donor in fatty ...
Genetic code
The genetic code is the set of rules by which information encoded within genetic material (DNA or mRNA sequences) is translated into proteins by living cells. Biological decoding is accomplished by the ribosome, which links amino acids in an order specified by mRNA, using transfer RNA (tRNA) molecules to carry amino acids and to read the mRNA three nucleotides at a time. The genetic code is highly similar among all organisms and can be expressed in a simple table with 64 entries.The code defines how sequences of these nucleotide triplets, called codons, specify which amino acid will be added next during protein synthesis. With some exceptions, a three-nucleotide codon in a nucleic acid sequence specifies a single amino acid. Because the vast majority of genes are encoded with exactly the same code (see the RNA codon table), this particular code is often referred to as the canonical or standard genetic code, or simply the genetic code, though in fact some variant codes have evolved. For example, protein synthesis in human mitochondria relies on a genetic code that differs from the standard genetic code.While the genetic code determines the protein sequence for a given coding region, other genomic regions can influence when and where these proteins are produced.