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Medical Applications of Bioinformatics
Medical Applications of Bioinformatics

... • BLASTX makes automatic translation (in all 6 reading frames) of your DNA query sequence to compare with protein databanks • TBLASTN makes automatic translation of an entire DNA database to compare with your protein query sequence • Only make a DNA-DNA search if you are working with a sequence that ...
BCPS Biology Reteaching Guide Genetics Vocab Chart
BCPS Biology Reteaching Guide Genetics Vocab Chart

... heterozygous individuals. Must have two recessive alleles in order for the gene to be expressed ...
Chapter 2 Nutrition Study Questions
Chapter 2 Nutrition Study Questions

... Please explain the significance of trans fatty acids (90) • These are the result of taking a liquid fat and making it a solid through a process called hydrogenation. Hydrogenation of fat alters its physical properties and makes it stay fresh longer. • The disadvantage of hydrogenation is that it ma ...
An in vitro RNA synthesis reaction was set up and allowed to
An in vitro RNA synthesis reaction was set up and allowed to

... inserted between positions 22 and 23 (position of insertion is indicated by an arrow on the figure above). Give the sequence of the new peptide produced by mutant B. Label the amino and carboxy termini of the peptide. d) One of these two mutants is fully functional, while the other is not. Which mut ...
Basic Bioinformatics
Basic Bioinformatics

... – The organism’s survival depends on the protein being functional, which means having the proper amino acids sequence – Since the genetic code is degenerate, many different DNA sequences will give identical proteins. – The protein 3-dimensional structure is even more conserved, because it is more cl ...
Basic Bioinformatics - NIU Department of Biological Sciences
Basic Bioinformatics - NIU Department of Biological Sciences

... – The organism’s survival depends on the protein being functional, which means having the proper amino acids sequence – Since the genetic code is degenerate, many different DNA sequences will give identical proteins. – The protein 3-dimensional structure is even more conserved, because it is more cl ...
Basic Bioinformatics
Basic Bioinformatics

... – The organism’s survival depends on the protein being functional, which means having the proper amino acids sequence – Since the genetic code is degenerate, many different DNA sequences will give identical proteins. – The protein 3-dimensional structure is even more conserved, because it is more cl ...
Dr Ishtiaq Lecture at GC Faisalabad
Dr Ishtiaq Lecture at GC Faisalabad

... • Irinotecan is used as chemotherapeutic agent for the treatment of metastatic colorectal cancer. • It produces adverse drug reactions in some patients. • genotyping assay is carried out to mutations in UGT1A1 gene for irinotecan prescribing. (Personalized Medicine 2006, 3(4): 415-419) ...
Transcription AND Translation
Transcription AND Translation

... – Peptide bond formation takes place: the polypeptide connects to the amino acid in the A site of the tRNA molecule and the ribosome acts as a catalyst for the formation of the bond. – Translocation takes place: the ribosome now moves the tRNA (that remains) to the P site, and it brings the growing ...
File
File

... CONCEPT CHECK ...
Lab #7 Exoenzymes, Differential and Selective Media
Lab #7 Exoenzymes, Differential and Selective Media

... Starch is a polymer made up of amylose, a polymer of glucose units and amylopectin. Amylopectin is a branched polymer containing phosphate groups (Figure 21.1). Bacteria capable of hydrolyzing starch produce the enzyme amylase. This enzymatic hydrolysis forms shorter polysaccharides called dextrins, ...
Document
Document

... Taxonomists must be careful to build cladograms based on homologous structures Biochemical evidence (immunological studies) can also be used to create cladograms. Combined with morphological data these studies tend to give a more reliable phylogeny ...
Biology-Chapter8 (Biology
Biology-Chapter8 (Biology

... 1. Cells secrete proteins, often as enzymes, that have been engineered or directed by the DNA in the nucleus. Which processes are involved in protein synthesis? A. transfer to RNA, then to amino acids B. transcription into RNA, then translation into amino acids C. replication of DNA, then transcript ...
Clicker Review-DNAProtein Syn Mutation
Clicker Review-DNAProtein Syn Mutation

... protein synthesis? 1. DNA 2. mRNA 3. tRNA 4. Both 1 and 2 5. Both 2 and 3 6. 6. All of the above ...
Download PDF
Download PDF

... Biochemistry is the study of the variety of chemical structures and chemical reactions that occur in living organisms. In order to truly understand the detailed mechanisms of these diverse reactions, one must assimilate aspects of organic chemistry, inorganic chemistry, and physical chemistry and ap ...
CH 8. DNA: The Universal Molecule of Life
CH 8. DNA: The Universal Molecule of Life

...  The chromosome number is more or less than that in the normal diploid or haploid cell.  Results in the addition or loss of whole chromosomes from a cell.  Normally in meiosis, homologous chromosomes come together and then segregate into separate cells, so that the gametes finish up with only one ...
Lecture 17 Protein synthesis pp101-110
Lecture 17 Protein synthesis pp101-110

... 3.13 A protein’s specific shape determines its function • A polypeptide chain contains hundreds or thousands of amino acids linked by peptide ...
Topic 4 revision notes - Mr Cartlidge`s Saigon Science Blog
Topic 4 revision notes - Mr Cartlidge`s Saigon Science Blog

... Explain that different sequences of amino acids give different shapes to protein molecules ...
here
here

... folding models have proved to be NP hard even in the 2-D case. ...
File
File

... rRNA – contains codes to make new riobsomes DNA – carries the amino acids to the ribosomes tRNA – combines with proteins to make up ribosomes mRNA – carries genetic codes from nucleus to the ribosomes ...
Unit 5: Hypercholesterolemia Section 1: Cholesterol A lipid that
Unit 5: Hypercholesterolemia Section 1: Cholesterol A lipid that

... A kind of fat often found in plant products that contains numerous double bonds between the carbons in the hydrocarbon tails of the fatty acids. A kind of fat, often found in meat & other animal products, which cannot incorporate any additional hydrogen atoms. A fatty acid in which all carbons in th ...
Protein Car Synthesis
Protein Car Synthesis

... The role of a Ribosome is to facilitate the translation of mRNA using tRNA into chains of Amino Acids (proteins synthesis). The function of the RNA Polymerase enzyme is to transcribe DNA code into a corresponding chain of RNA. One Gene codes for one polypeptide chain (protein). Cells use gene regula ...
workshop module 6: dna, rna and proteins - Peer
workshop module 6: dna, rna and proteins - Peer

... helix. The complementary copy is called mRNA or “messenger RNA,” and the process of forming RNA from DNA is called transcription. The mRNA leaves the nucleus where it is threaded into a ribosome. The ribosome is made of rRNA (ribosomal RNA) and proteins. The ribosome then reads the sequence of the m ...
Mechanism of ribonuclease
Mechanism of ribonuclease

... Mechanism of ribonuclease ...
RNA STRUCTURE - mbbsclub.com
RNA STRUCTURE - mbbsclub.com

... percent of the RNA in the cell.  The most heterogeneous type of RNA in size and base sequence.  The mRNA carries genetic information from the nuclear DNA to the cytosol, where it is used as the template for protein synthesis. ...
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Expanded genetic code



An expanded genetic code is an artificially modified genetic code in which one or more specific codons have been re-allocated to encode an amino acid that is not among the 22 encoded proteinogenic amino acids.The key prerequisites to expand the genetic code are: the non-standard amino acid to encode, an unused codon to adopt, a tRNA that recognises this codon, and a tRNA synthase that recognises only that tRNA and only the non-standard amino acid.Expanding the genetic code is an area of research of synthetic biology, an applied biological discipline whose goal is to engineer living systems for useful purposes. The genetic code expansion enriches the repertoire of useful tools available to science.
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