PowerPoint 프레젠테이션
... family proteins such as p65 and p50. This phosphorylation is the signal for ubiquitination of IkB by a ubiquitin ligase (UbL). This produces IkB for degradation by the proteasomes, which then results in the release of NF-kB. The transcription factor is now free to become translocated to the nucleus ...
... family proteins such as p65 and p50. This phosphorylation is the signal for ubiquitination of IkB by a ubiquitin ligase (UbL). This produces IkB for degradation by the proteasomes, which then results in the release of NF-kB. The transcription factor is now free to become translocated to the nucleus ...
Immunology (A)
... T cells require co-stimulation for activation -- binding of the TCR to MHC/peptide (signal 1) is not enough to activate a T cell by itself.(3’) B7 and other costimulatory molecules on an APC binds to CD28 and other costimlatory molecules on the T cell to deliver a co-stimulatory signal (signal 2)(2’ ...
... T cells require co-stimulation for activation -- binding of the TCR to MHC/peptide (signal 1) is not enough to activate a T cell by itself.(3’) B7 and other costimulatory molecules on an APC binds to CD28 and other costimlatory molecules on the T cell to deliver a co-stimulatory signal (signal 2)(2’ ...
Poster
... Celiac disease (CD) is an inflammatory disease of the gastrointestinal tract. Many people are affected by this disease, but are undiagnosed. They dismiss the digestive and neurological symptoms as nothing more than malaise. Those who are diagnosed need a controlled, gluten-free diet to alleviate sym ...
... Celiac disease (CD) is an inflammatory disease of the gastrointestinal tract. Many people are affected by this disease, but are undiagnosed. They dismiss the digestive and neurological symptoms as nothing more than malaise. Those who are diagnosed need a controlled, gluten-free diet to alleviate sym ...
Immune Practice Test
... The first line of defense against pathogens is to a) block pathogen from entering the body. b) kill infected cells. c) send signals to increase immune cell formation. d) kill the pathogen. ...
... The first line of defense against pathogens is to a) block pathogen from entering the body. b) kill infected cells. c) send signals to increase immune cell formation. d) kill the pathogen. ...
Lecture exam #2 review guide: covered chapters 17, 22, 23
... APC (antigen presenting cells) - Dendritic cells and some macrophages. Type II MHC displays antigen to activate T cells. T-cells must be activated by APCs along with cytokines (safety) ▫ Plot out the “training” of a T-cell. Where does this occur? How must antigen be presented? What tests must a T-ce ...
... APC (antigen presenting cells) - Dendritic cells and some macrophages. Type II MHC displays antigen to activate T cells. T-cells must be activated by APCs along with cytokines (safety) ▫ Plot out the “training” of a T-cell. Where does this occur? How must antigen be presented? What tests must a T-ce ...
Document
... H-Y antigen. You use the α and β TCR genes for this H-2k-restricted TCR to prepare transgenic mice with either a H-2k or H-2d haplotype. The transgenic mice produce H-Y specific T-cells without any ...
... H-Y antigen. You use the α and β TCR genes for this H-2k-restricted TCR to prepare transgenic mice with either a H-2k or H-2d haplotype. The transgenic mice produce H-Y specific T-cells without any ...
35-2 Defense Against Infection Worksheet
... 10. A substance that triggers the immune response is known as a (n) 11. The main role of immune-system cells. ...
... 10. A substance that triggers the immune response is known as a (n) 11. The main role of immune-system cells. ...
Immunity in the gut
... As many pathogens enter the body via the intestinal mucosa, it is vital the gut-associated lymphoid tissues can provide effective immune responses when necessary. However, inappropriate responses against innocuous food and commensal antigens lead to inflammatory disorders such as coeliac disease and ...
... As many pathogens enter the body via the intestinal mucosa, it is vital the gut-associated lymphoid tissues can provide effective immune responses when necessary. However, inappropriate responses against innocuous food and commensal antigens lead to inflammatory disorders such as coeliac disease and ...
The Immune System
... produced in the bone marrow & stored in the thymus gland, giving its name it travels in the blood acting as a sentry identifying invaders by their antigens once identified another T-cell (helper) releases a chemical called interferons to call other WBC into action and lymphokines which activate the ...
... produced in the bone marrow & stored in the thymus gland, giving its name it travels in the blood acting as a sentry identifying invaders by their antigens once identified another T-cell (helper) releases a chemical called interferons to call other WBC into action and lymphokines which activate the ...
Immune System Notes: Part I
... (occurs before birth and is completed a few months after birth) Immature B cells produce antibodies while still in the bone marrow and insert these antibodies into their cell membranes (genes determine this) Antibody bearing B cells enter the blood stream and travel to the lymph nodes, spleen an ...
... (occurs before birth and is completed a few months after birth) Immature B cells produce antibodies while still in the bone marrow and insert these antibodies into their cell membranes (genes determine this) Antibody bearing B cells enter the blood stream and travel to the lymph nodes, spleen an ...
Immunosenescence and Its Aplications to Artificial Immune
... J.: Naive T cells are maintained by thymic output in early ages but by proliferation without phenotypic change after twenty. Immunology and Cell Biology (2003) 487-495 Wenisch, C., Patruta, S., Daxbrock, F., Krause, R., Horl, R.: Effect of age on human neutrophil function. ...
... J.: Naive T cells are maintained by thymic output in early ages but by proliferation without phenotypic change after twenty. Immunology and Cell Biology (2003) 487-495 Wenisch, C., Patruta, S., Daxbrock, F., Krause, R., Horl, R.: Effect of age on human neutrophil function. ...
Document
... As many pathogens enter the body via the intestinal mucosa, it is vital the gut-associated lymphoid tissues can provide effective immune responses when necessary. However, inappropriate responses against innocuous food and commensal antigens lead to inflammatory disorders such as coeliac disease and ...
... As many pathogens enter the body via the intestinal mucosa, it is vital the gut-associated lymphoid tissues can provide effective immune responses when necessary. However, inappropriate responses against innocuous food and commensal antigens lead to inflammatory disorders such as coeliac disease and ...
Marginal zone B cells – super potent, and super dangerous? Heike
... The immune system is our best weapon in the fight against viruses and harmful bacteria. It possesses the amazing ability to distinguish between foreign substances and the body's own substances and cells. However, sometimes the immune system does not work properly and makes the serious mistake of att ...
... The immune system is our best weapon in the fight against viruses and harmful bacteria. It possesses the amazing ability to distinguish between foreign substances and the body's own substances and cells. However, sometimes the immune system does not work properly and makes the serious mistake of att ...
File - BIOLOGY Mound
... • Lymphocytes (Helper T cells) bind to the presented antigen and are activated. • Lymphocytes (B cells) produce different antibodies and also bind to pathogens and attach antigens to their surface. • T cells which recognize the antigen on the B cells, send a signal message to the specific B cells to ...
... • Lymphocytes (Helper T cells) bind to the presented antigen and are activated. • Lymphocytes (B cells) produce different antibodies and also bind to pathogens and attach antigens to their surface. • T cells which recognize the antigen on the B cells, send a signal message to the specific B cells to ...
File
... cell’s membrane 3. The pores allow a “signal” molecule from the NK cell to enter the target cell and trigger a genetically controlled series of events 4. The target cell then switches on a “suicide” gene, and “suicide” proteins are released 5. “Suicide” proteins function as self-destructive (degrada ...
... cell’s membrane 3. The pores allow a “signal” molecule from the NK cell to enter the target cell and trigger a genetically controlled series of events 4. The target cell then switches on a “suicide” gene, and “suicide” proteins are released 5. “Suicide” proteins function as self-destructive (degrada ...
Immune System
... 3. Antigens are particles which can stimulate receptors on lymphocytes only part of the foreign invader is antigenic 4. Antibodies are proteins produced by lymphocytes light chain binds antigen Fig. 13.13 heavy chain binds to “destructive” processes in body Q: Is the light chain or the heavy c ...
... 3. Antigens are particles which can stimulate receptors on lymphocytes only part of the foreign invader is antigenic 4. Antibodies are proteins produced by lymphocytes light chain binds antigen Fig. 13.13 heavy chain binds to “destructive” processes in body Q: Is the light chain or the heavy c ...
The_Specific_Immune_Response
... the body that is recognised as foreign. They may kill the invading organism itself, or they may kill body cells that have been infected with the organism. The cells literally line up, membrane to membrane, then the killer cell punches holes in the other cell’s membrane. It loses cytoplasm and dies. ...
... the body that is recognised as foreign. They may kill the invading organism itself, or they may kill body cells that have been infected with the organism. The cells literally line up, membrane to membrane, then the killer cell punches holes in the other cell’s membrane. It loses cytoplasm and dies. ...
Document
... Central tolerance to self antigens is acquired during development through the elimination or silencing of lymphocytes capable of binding self antigens Peripheral tolerance is induced in mature lymphocytes in the periphery ...
... Central tolerance to self antigens is acquired during development through the elimination or silencing of lymphocytes capable of binding self antigens Peripheral tolerance is induced in mature lymphocytes in the periphery ...
lectyre1-Introductio..
... B cells • B cells display surface IgM which serves as antigen receptor • Surface IgD on some B cells also serves as an antigen receptor • Pre B cells are found in bone marrow and mature B cells are found circulating in ...
... B cells • B cells display surface IgM which serves as antigen receptor • Surface IgD on some B cells also serves as an antigen receptor • Pre B cells are found in bone marrow and mature B cells are found circulating in ...
T cell
T cells or T lymphocytes are a type of lymphocyte (in turn, a type of white blood cell) that plays a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T-cell receptor (TCR) on the cell surface. They are called T cells because they mature in the thymus (although some also mature in the tonsils). The several subsets of T cells each have a distinct function. The majority of human T cells rearrange their alpha/beta T cell receptors and are termed alpha beta T cells and are part of adaptive immune system. Specialized gamma delta T cells, which comprise a minority of T cells in the human body (more frequent in ruminants), have invariant TCR (with limited diversity), can effectively present antigens to other T cells and are considered to be part of the innate immune system.