Dealing with Garbage is the Immune System`s Main Job
... promotes antibody production by B cells to facilitate trash clearance. Dendritic cells at the site pick up garbage that contains PAMPS or DAMPS. They respond to the stimulus, spread a local cytokine alarm, mature, and then run to the lymph node to direct T cells to act. During their maturation and t ...
... promotes antibody production by B cells to facilitate trash clearance. Dendritic cells at the site pick up garbage that contains PAMPS or DAMPS. They respond to the stimulus, spread a local cytokine alarm, mature, and then run to the lymph node to direct T cells to act. During their maturation and t ...
Immune Strategies to Infection
... This occurs as a result of antigen presentation to naïve T cells at the lymph nodes, which get activated and then travel to the site of infection to elicit a response (cell mediated), or antigen may remain in the lymph nodes, activating B cells for antibody production (humoral). What determines whet ...
... This occurs as a result of antigen presentation to naïve T cells at the lymph nodes, which get activated and then travel to the site of infection to elicit a response (cell mediated), or antigen may remain in the lymph nodes, activating B cells for antibody production (humoral). What determines whet ...
The Immune System
... • Produced in bone marrow, mature in thymus. • Antigen must be presented in groove of HLA molecule. • Cytotoxic T cells destroy non-self protein-bearing cells. • Helper T cells secrete cytokines that control the immune response. ...
... • Produced in bone marrow, mature in thymus. • Antigen must be presented in groove of HLA molecule. • Cytotoxic T cells destroy non-self protein-bearing cells. • Helper T cells secrete cytokines that control the immune response. ...
The Immune System
... thymus. • Antigen must be presented in groove of HLA molecule. • Cytotoxic T cells destroy non-self protein-bearing cells. • Helper T cells secrete cytokines that control the immune response. ...
... thymus. • Antigen must be presented in groove of HLA molecule. • Cytotoxic T cells destroy non-self protein-bearing cells. • Helper T cells secrete cytokines that control the immune response. ...
Kuby Immunology 6/e - Dr. Jennifer Capers, PhD
... Various cytokines and inflammatory mediators act on local blood vessels 4 steps of extravasation: ○ Rolling, mediated by selectins ○ Activation by chemoattractant stimulus ○ Arrest and adhesion, mediated by integrins binding to Ig-family ○ Transendothelial migration ...
... Various cytokines and inflammatory mediators act on local blood vessels 4 steps of extravasation: ○ Rolling, mediated by selectins ○ Activation by chemoattractant stimulus ○ Arrest and adhesion, mediated by integrins binding to Ig-family ○ Transendothelial migration ...
Summary
... equipped to take up and process antigens. Under normal circumstances, antigens taken up by DC will be self antigens, or antigens from harmless bacteria, in which case DC will not become activated and will not activate effector cells of the adaptive immune system, i.e. the T- and B cells. When DC tak ...
... equipped to take up and process antigens. Under normal circumstances, antigens taken up by DC will be self antigens, or antigens from harmless bacteria, in which case DC will not become activated and will not activate effector cells of the adaptive immune system, i.e. the T- and B cells. When DC tak ...
acquired immunity
... Each human usually expresses: 3 types of MHC class I (A, B, C) and 3 types of MHC class II (DR, DP,DQ) ...
... Each human usually expresses: 3 types of MHC class I (A, B, C) and 3 types of MHC class II (DR, DP,DQ) ...
Antigenicity - immunology.unideb.hu
... • IgG - gamma (γ) heavy chains • IgM - mu (μ) heavy chains • IgA - alpha (α) heavy chains • IgD - delta (δ) heavy chains • IgE - epsilon (ε) heavy chains ...
... • IgG - gamma (γ) heavy chains • IgM - mu (μ) heavy chains • IgA - alpha (α) heavy chains • IgD - delta (δ) heavy chains • IgE - epsilon (ε) heavy chains ...
Lecture 4: Host Response to Infection
... Induction of the humoral and CMI responses involve parallel mechanisms: − Effectors arise from initially naïve precursor cells (B and T cells) − Precursors bear surface receptors with specificities generated at random (Ig, TcR) − Naïve precursors differentiate (acquire effector function) because of ...
... Induction of the humoral and CMI responses involve parallel mechanisms: − Effectors arise from initially naïve precursor cells (B and T cells) − Precursors bear surface receptors with specificities generated at random (Ig, TcR) − Naïve precursors differentiate (acquire effector function) because of ...
Lecture notes
... draining lymph nodes via the afferent lymphatics. Some antigen is carried free in the afferent lymph, whereas some is taken up in the infected tissues by dendritic cells (DC), which are activated to migrate into the lymphatics and thence to the draining lymph nodes. ...
... draining lymph nodes via the afferent lymphatics. Some antigen is carried free in the afferent lymph, whereas some is taken up in the infected tissues by dendritic cells (DC), which are activated to migrate into the lymphatics and thence to the draining lymph nodes. ...
(white blood cells).
... T cells and B cells are the major cellular components of the adaptive immune response T cells are involved in cell-mediated immunity B cells are primarily responsible for humoral immunity (relating to antibodies) The function of T cells and B cells is to recognize specific “non-self” antigens, durin ...
... T cells and B cells are the major cellular components of the adaptive immune response T cells are involved in cell-mediated immunity B cells are primarily responsible for humoral immunity (relating to antibodies) The function of T cells and B cells is to recognize specific “non-self” antigens, durin ...
Lecture 18
... – Their main function is to process antigen material and present it on the surface to other cells of the immune system, thus functioning as antigen-presenting cells ...
... – Their main function is to process antigen material and present it on the surface to other cells of the immune system, thus functioning as antigen-presenting cells ...
The Specific/Adaptive Immune Response
... –Cells infected with viruses and other intracellular pathogens –Abnormal cells, such as cancer cells Helper T Cells (TH Cells) –Distinguished by the CD4 cell-surface glycoprotein –Function to “help” regulate the activities of B cells and cytotoxic T cells during an immune response –Secrete various s ...
... –Cells infected with viruses and other intracellular pathogens –Abnormal cells, such as cancer cells Helper T Cells (TH Cells) –Distinguished by the CD4 cell-surface glycoprotein –Function to “help” regulate the activities of B cells and cytotoxic T cells during an immune response –Secrete various s ...
The immune response against dying tumor cells: avoid
... sacrifice via programmed cell death (PCD) of infected cells; a response that is found in all metazoan phyla including plants (which do not possess any mobile cells and hence lack an immune system). In mammals, microbial invasion does not only trigger PCD of infected cells but also elicits an immune ...
... sacrifice via programmed cell death (PCD) of infected cells; a response that is found in all metazoan phyla including plants (which do not possess any mobile cells and hence lack an immune system). In mammals, microbial invasion does not only trigger PCD of infected cells but also elicits an immune ...
Ovplyvnenie imunitnej odpovede
... • Reinstilation – stimulised cells specifically target tumor. IL-2 can increase proliferation of anti tumor T cells in vivo ...
... • Reinstilation – stimulised cells specifically target tumor. IL-2 can increase proliferation of anti tumor T cells in vivo ...
Foundations in Microbiology
... when presented in association with an MHC carrier. • T cells secrete cytokines that act on other cells. • Sensitized T cells proliferate into long-lasting memory T cells. ...
... when presented in association with an MHC carrier. • T cells secrete cytokines that act on other cells. • Sensitized T cells proliferate into long-lasting memory T cells. ...
Chapter 8 Immune Organs
... immune system consisting of lymphocytes and APCs (such as Langerhan’s cell) ...
... immune system consisting of lymphocytes and APCs (such as Langerhan’s cell) ...
CfE Higher Human Biology Unit 4 – Immunology and Public Health
... cells causing vasodilation and increased capillary permeability. The increased blood flow and secretion of cytokines leads to an accumulation of phagocytes and the delivery of antimicrobial proteins and clotting elements to the site of infection. I can describe the structure of Phagocytes and apopto ...
... cells causing vasodilation and increased capillary permeability. The increased blood flow and secretion of cytokines leads to an accumulation of phagocytes and the delivery of antimicrobial proteins and clotting elements to the site of infection. I can describe the structure of Phagocytes and apopto ...
THE IMMUNE SYSTEM
... antigens for phagocytes • Some work as antitoxins i.e. they block toxins for e.g. those causing diphtheria and tetanus • Some attach to bacterial flagella making them less active and easier for phagocytes to ...
... antigens for phagocytes • Some work as antitoxins i.e. they block toxins for e.g. those causing diphtheria and tetanus • Some attach to bacterial flagella making them less active and easier for phagocytes to ...
T cell
T cells or T lymphocytes are a type of lymphocyte (in turn, a type of white blood cell) that plays a central role in cell-mediated immunity. They can be distinguished from other lymphocytes, such as B cells and natural killer cells (NK cells), by the presence of a T-cell receptor (TCR) on the cell surface. They are called T cells because they mature in the thymus (although some also mature in the tonsils). The several subsets of T cells each have a distinct function. The majority of human T cells rearrange their alpha/beta T cell receptors and are termed alpha beta T cells and are part of adaptive immune system. Specialized gamma delta T cells, which comprise a minority of T cells in the human body (more frequent in ruminants), have invariant TCR (with limited diversity), can effectively present antigens to other T cells and are considered to be part of the innate immune system.