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Cytokines and Chemokines
Cytokines and Chemokines

... Cell adhesion molecules • CAM: A group of proteins involved in adhesion of cell to cell or cell to extra-cellular matrix (ECM), such as ...
The Clinical Research of Chimeric Antigen
The Clinical Research of Chimeric Antigen

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... Tolerance or immunity can also be influenced by the tissue microenvironment Immuno-suppressive mediators are secreted by the foetus and placenta (eg TGF-b) and prevent “rejection” Can we manipulate the immune system to avoid rejection of liver or kidney grafts? ...
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The Human Immune System: Basics and then some…
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... or dead pathogen, which to certainare diseases… allows body to do its primary immune response without the risk of It’s because after every encounter with a pathogen, bothsickness. the T cells and the B cells actual differentiate into an inactive form of their parent cell. They remain inactive until ...
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Document
Document

... 1. The white blood cells recognize ‘foreign' molecules or so called antigens, such as microbes, pollen grains or the toxins made by bacteria. 2. The presence of antigens in the body stimulates the immune system to produce antibodies. Each type of antigen causes the production of new antibodies speci ...
Feather Evolution
Feather Evolution

... Cost and convenience are considered the two major obstacles to large-scale use of antibodies against PCSK9. The importance of inconvenience as a barrier to antibody therapy may be overstated. Clinical experience with immunotherapy for allergy relief indicates that many patients will tolerate regular ...
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Monoclonal antibody



Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.
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