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Perioperative management of ambulatory surgical patients
Perioperative management of ambulatory surgical patients

... to mimic naturally occurring peptides released in response to carbohydrate or fat intake. These drugs are unlikely to cause hypoglycemia, unless combined with other drugs such as a sulfonylurea [21,27,28]. This group includes the oral DPP-4 inhibitor (Januvia) and the injectables exenatide (Byett ...
Pancreatitis
Pancreatitis

... What is the sphincter of Oddi? What common pain medication causes spasms of this sphinter? Which digestive enzymes are secreted by the pancreas? What is the hallmark lab abnormality in pancreatitis? ...
Congenital hyperinsulinism
Congenital hyperinsulinism

... a signal transduction system whereby metabolic changes in the b-cell are linked to regulated insulin secretion.24 The metabolic changes are linked to regulated insulin secretion by potassium channels (KATP) located in the pancreatic b-cell membrane.25 Each KATP channel consists of a heteromultimeric ...
Name Date ______ Lab genetic engineering using bacteria In this
Name Date ______ Lab genetic engineering using bacteria In this

... be inserted into the bacterial plasmid. This recombinant DNA is then put into a bacterial cell where it can be duplicated quickly at a low cost because bacteria reproduce quickly. ...
Presentation
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... 1. Improve A1C and other measures of quality care ...
Children’s Emergency Services
Children’s Emergency Services

... 4. Reduction of bones including splitting and crutch walking 5. Enemas 6. NG tube placement 7. Suctioning (nasopharyngeal, oral, tracheal, endotracheal) 8. Assist with resuscitation (intubation, chest compressions, fluid/blood/medication administration) 9. Lumbar Puncture 10. Conscious sedation 11. ...
Obesity and Bariatric Surgery
Obesity and Bariatric Surgery

... Obesity is regarded as a chronic medical disease with serious health implications caused by a complex set of factors. MICRONUTRIENTS AND OBESITY Obesity is a complex, multi-faceted, chronic disease involving social, environmental, genetic, physiological, metabolic, behavioral and psychological compo ...
Assessment and Management of Patients With Diabetes Mellitus
Assessment and Management of Patients With Diabetes Mellitus

...  Implantable and inhalant insulin delivery  Transplantation of pancreatic cells ...
PSI 10 Best Practices
PSI 10 Best Practices

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ISMP Medication Safety Alert
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A Newsletter for Those Who Care for Children
A Newsletter for Those Who Care for Children

... and developing rapidly, placing an additional demand on the pancreas to produce additional insulin. This newsletter will compare the pathophysiology of type 1 versus type 2 diabetes. Pediatric risk factors for type 2 diabetes will be described, which are key for healthcare providers to note during p ...
Diabetes Management in the Hospital: Case Studies
Diabetes Management in the Hospital: Case Studies

... d) Begin fast acting analog = 50% TDI divided by 3 (give 3 times a day immediately before meals). e) Continue IV insulin infusion for 2 hours after initiation of subcutaneous therapy. f) Refer to Subcutaneous Insulin Standing Orders for administration times and dosage adjustments. g) Refer patient f ...
Glycaemic Control in Type 2 Diabetes
Glycaemic Control in Type 2 Diabetes

... First introduced in the late 1950s the biguanide Metformin decreases hepatic glucose production and may improve peripheral glucose disposal, thus decreasing insulin resistance. Activation of the energy-regulating enzyme AMP-kinase in liver and muscle is a principal mode of action although it has bee ...
A (Very) - Diabetes in Control
A (Very) - Diabetes in Control

... HLA studies show that patients diagnosed with diabetes in the first 6 months of life are very likely to have monogenic neonatal diabetes rather than type 1 diabetes (Except IPEX-related). Neonatal diabetes is a rare disorder – incidence of between 1 in 215,000-500,000 live births – Several genes are ...
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... b. IM c. As retention enema d. PO or via NG tube 3. Which of the following IV orders should the nurse question if written for a patient cirrhosis of the liver? a. “IV of D5W to infuse at 75 ml/hour.” b. “IV LR@ 100 mg/hour.” c. “IV D5NS to infuse over 8 hours.” d. “IV 1 liter @ 100 ml per hour.” Que ...
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... 'Diabetes' is the abbreviated term for a condition known as 'diabetes mellitus'. There are two main forms of diabetes in the general population, type 1 and type 2. A third type, known as 'gestational diabetes' is associated with pregnancy. All forms of diabetes involve a reduced ability of the body ...
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... 6. During a teaching session, the nurse tells the client that 50% to 60% of daily calories should come from carbohydrates. What should the nurse say about the types of carbohydrates that can be eaten? a. Simple carbohydrates are absorbed more c. Simple sugars should never be consumed rapidly than co ...
Summary Putting it All Together
Summary Putting it All Together

...  Diuretics are powerful in their ability to decrease brain volume and, therefore, to decrease ICP. Mannitol, an osmotic diuretic, is the most common diuretic used. Mannitol is a sugar alcohol that draws water out from the brain into the intravascular compartment. It has a rapid onset of action and ...
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Diabetic Ketoacidosis DKA
Diabetic Ketoacidosis DKA

... adults and people in their teenage years. DKA can develop in a new-onset type I diabetic or a diabetic who misses insulin doses9. Often it occurs with poor insulin compliance and lack of knowledge about managing insulin administration in acute illness. The patient who is feeling unwell may believe t ...
- Hamad Medical Corporation
- Hamad Medical Corporation

... the patient may receive saline rather than insulin for a few hours, resulting in higher-than-expected glucose levels and titration of insulin to higher doses The result would then be an unexpectedly low glucose several hours later Other details of administration, such as type of IV tubing used and h ...
Diabetes and Eating Disorders
Diabetes and Eating Disorders

... binge/purge less often, meet criteria for anorexia but is normal WT or have regular menses, purging after eating small amounts of food, chewing/spitting, milder subthreshold variants.  Most people with ED & Type 1 Diabetes will be in the ED-NOS category ...
Part 1: Blood Glucose Test Strips in People with Type 2
Part 1: Blood Glucose Test Strips in People with Type 2

... ‘initial’ restriction pathway. This recommendation was consistent with the findings of the Cochrane Review (2012) that indicate a minimal clinical benefit in improving blood glucose control at six months, which disappeared after 12 months’ follow-up. ...
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... Important Tests for Type 2 Diabetes ...
Dr Shahjada Selim
Dr Shahjada Selim

... Viruses + other environmental agents have been shown to be triggering factors. Viruses can damage beta cells by: 1.Direct invasion. 2.Triggering an auto immune response. ...
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Artificial pancreas



The artificial pancreas is a technology in development to help people with diabetes automatically control their blood glucose level by providing the substitute endocrine functionality of a healthy pancreas.There are several important exocrine (digestive) and endocrine (hormonal) functions of the pancreas, but it is the lack of insulin production which is the motivation to develop a substitute. While the current state of insulin replacement therapy is appreciated for its life-saving capability, the task of manually managing the blood sugar level with insulin alone is arduous and inadequate.The goal of the artificial pancreas is two-fold:to improve insulin replacement therapy until glycemic control is practically normal as evident by the avoidance of the complications of hyperglycemia, and to ease the burden of therapy for the insulin-dependent.Different approaches under consideration include: the medical equipment approach—using an insulin pump under closed loop control using real-time data from a continuous blood glucose sensor. the bioengineering approach—the development of a bio-artificial pancreas consisting of a biocompatible sheet of encapsulated beta cells. When surgically implanted, the islet sheet will behave as the endocrine pancreas and will be viable for years. the gene therapy approach—the therapeutic infection of a diabetic person by a genetically engineered virus which causes a DNA change of intestinal cells to become insulin-producing cells.
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