Sphingolipids - Their Metabolic Pathways and - Limes-Institut-Bonn
... nerve growth factor,[17] and ganglioside GM3 inhibits tyrosine phosphorylation of the epidermal growth factor receptor.[18] Many physiological processes can be affected by GSLs, for example embryogenesis, neuronal cell and leukocyte differentiation, cell adhesion, and signal transduction.[19] Lipoph ...
... nerve growth factor,[17] and ganglioside GM3 inhibits tyrosine phosphorylation of the epidermal growth factor receptor.[18] Many physiological processes can be affected by GSLs, for example embryogenesis, neuronal cell and leukocyte differentiation, cell adhesion, and signal transduction.[19] Lipoph ...
Disease concepts and treatment by tribal healers of an Amazonian
... plant use, viewed by missionaries as compatible to Christian faith, was deemed acceptable but not strongly condoned. Concerning the present state of the spiritual aspects of Trio shamanism, Rivière commented in 1994 that the "old ideas have not disappeared" [35]. Anecdotal evidence reported by Hernd ...
... plant use, viewed by missionaries as compatible to Christian faith, was deemed acceptable but not strongly condoned. Concerning the present state of the spiritual aspects of Trio shamanism, Rivière commented in 1994 that the "old ideas have not disappeared" [35]. Anecdotal evidence reported by Hernd ...
10637_2014_106_MOESM1_ESM
... poor.(3) Chemotherapy is the standard of care for CRPC. Docetaxel has recently been considered the new standard cytotoxic agent based on the results of two randomized trials that reported a statistically significant increase in median survival.(4, 5) For patients that progressed despite docetaxel ba ...
... poor.(3) Chemotherapy is the standard of care for CRPC. Docetaxel has recently been considered the new standard cytotoxic agent based on the results of two randomized trials that reported a statistically significant increase in median survival.(4, 5) For patients that progressed despite docetaxel ba ...
Read - DIA
... in two Phase I trials. The study U24 was based exclusively on patient referals while study N25 implicated an active participation of the investigator in the clinical study conduct. Results: In study U24, 12 patients were to be enrolled in the study. Although 54 patients were refered by the offsite s ...
... in two Phase I trials. The study U24 was based exclusively on patient referals while study N25 implicated an active participation of the investigator in the clinical study conduct. Results: In study U24, 12 patients were to be enrolled in the study. Although 54 patients were refered by the offsite s ...
Get your patients off to the right start with insulin therapy
... LEVEMIR® is a recombinant human insulin analog for once- or twicedaily subcutaneous administration. Patients treated with LEVEMIR® once-daily should administer the dose with the evening meal or at bedtime. Patients who require twice-daily dosing can administer the evening dose with the evening meal, ...
... LEVEMIR® is a recombinant human insulin analog for once- or twicedaily subcutaneous administration. Patients treated with LEVEMIR® once-daily should administer the dose with the evening meal or at bedtime. Patients who require twice-daily dosing can administer the evening dose with the evening meal, ...
The bronchiectasis severity index and FACED score for bronchiectasis EDITORIAL
... scores reflect disease severity. So what is the relationship between the BSI and FACED scoring system? Should the BSI and FACED score be utilised alone or complementarily in clinical settings? In an editorial previously published in the European Respiratory Journal (ERJ), SALEH and HURST [14] commen ...
... scores reflect disease severity. So what is the relationship between the BSI and FACED scoring system? Should the BSI and FACED score be utilised alone or complementarily in clinical settings? In an editorial previously published in the European Respiratory Journal (ERJ), SALEH and HURST [14] commen ...
The Spirogram IDIOPATHIC PULMONARY FIBROSIS: New Approaches to Therapy
... Although several forms of therapy have been used to treat IPF over the past three decades, none have been shown clearly to be effective in randomized placebo-controlled trials. A recent study sponsored by the US National Institutes of Health (PANTHER) showed no benefit and substantially increased ri ...
... Although several forms of therapy have been used to treat IPF over the past three decades, none have been shown clearly to be effective in randomized placebo-controlled trials. A recent study sponsored by the US National Institutes of Health (PANTHER) showed no benefit and substantially increased ri ...
Counterpoint: Long-Term Antibiotic Therapy Improves Persistent
... been experimentally infected with B. burgdorferi by tick exposure, treatment with high doses of amoxicillin or doxycycline for 30 days diminished persistent infection but failed to eliminate it. Furthermore, when dogs were observed for a 500-day postinfection period (the equivalent of 3–4 human year ...
... been experimentally infected with B. burgdorferi by tick exposure, treatment with high doses of amoxicillin or doxycycline for 30 days diminished persistent infection but failed to eliminate it. Furthermore, when dogs were observed for a 500-day postinfection period (the equivalent of 3–4 human year ...
Interventions for Treating Persons with Dementia Objectives
... principles to provide constructive engagement, meaningful activity, and practice of skills to older adults. – Uses principles from the Montessori classroom to help older adults maintain independence and learn new skills older adults maintain independence and learn new skills. – Camp and other rese ...
... principles to provide constructive engagement, meaningful activity, and practice of skills to older adults. – Uses principles from the Montessori classroom to help older adults maintain independence and learn new skills older adults maintain independence and learn new skills. – Camp and other rese ...
University of Toronto Lupus Clinic Newsletter
... Heart Disease in SLE – A Major Focus A major focus of our research over the last few years has been in the area of heart disease in SLE patients. Women with SLE are known to develop atherosclerotic heart disease (thickening of arteries) earlier than the general population. Because of these changes, ...
... Heart Disease in SLE – A Major Focus A major focus of our research over the last few years has been in the area of heart disease in SLE patients. Women with SLE are known to develop atherosclerotic heart disease (thickening of arteries) earlier than the general population. Because of these changes, ...
New developments to optimize postprandial glucose control with
... approaching the time–action profile of endogenous insulin secretion. Indeed, the time-topeak insulin levels vary between 45 and 90 min after subcutaneous injection, and the time to the maximal glucose-lowering effect varies between 85 and 198 min after injection (Table 1) . Consequently, postprandia ...
... approaching the time–action profile of endogenous insulin secretion. Indeed, the time-topeak insulin levels vary between 45 and 90 min after subcutaneous injection, and the time to the maximal glucose-lowering effect varies between 85 and 198 min after injection (Table 1) . Consequently, postprandia ...
brochure - Butler Hospital
... This brochure should provide you with the essential information on CADASIL. Since this is a rare and relatively new disease, information for patients and family members is still quite sparse—to our knowledge there is no book of advice for lay people. Web sites on the Internet can be of inconsistent ...
... This brochure should provide you with the essential information on CADASIL. Since this is a rare and relatively new disease, information for patients and family members is still quite sparse—to our knowledge there is no book of advice for lay people. Web sites on the Internet can be of inconsistent ...
DIABETES KNOWLEDGE AND MEDICATION ADHERENCE AMONG GERIATRIC PATIENT WITH Original Article
... three times daily.Adherence rates were also found to be decreased to 41%, 35%, and 30% in patients who received none, one, and two previous medications, respectively [25]. Thus, higher medication adherence rate observed among geriatrics in this study could be contributed to the fact that majority of ...
... three times daily.Adherence rates were also found to be decreased to 41%, 35%, and 30% in patients who received none, one, and two previous medications, respectively [25]. Thus, higher medication adherence rate observed among geriatrics in this study could be contributed to the fact that majority of ...
AusPAR: Dulaglutide rch - Therapeutic Goods Administration
... population) by 2030. There are 183 million people with undiagnosed diabetes. T2DM has a complex pathophysiology that is characterised by deficient insulin activity arising from decreased insulin secretion secondary to β cell failure, compromised insulin action in peripheral target tissues (insulin r ...
... population) by 2030. There are 183 million people with undiagnosed diabetes. T2DM has a complex pathophysiology that is characterised by deficient insulin activity arising from decreased insulin secretion secondary to β cell failure, compromised insulin action in peripheral target tissues (insulin r ...
Perspective Paul M Lantos
... backache, fatigue, irritability and cognitive dysfunction (particularly perceived difficulty with memory and concentration). While some patients have objective cognitive deficits, many who subjectively complain of cognitive dysfunction are found to be normal when formally tested [3,7,61–65] . The at ...
... backache, fatigue, irritability and cognitive dysfunction (particularly perceived difficulty with memory and concentration). While some patients have objective cognitive deficits, many who subjectively complain of cognitive dysfunction are found to be normal when formally tested [3,7,61–65] . The at ...
Diagnosis and treatment of Wilson disease: An update
... Weight of evidence/opinion is in favor of usefulness/ efficacy. Usefulness/efficacy is less well established by evidence/opinion. Conditions for which there is evidence and/or general agreement that a procedure/treatment is not useful/ effective and in some cases may be harmful. ...
... Weight of evidence/opinion is in favor of usefulness/ efficacy. Usefulness/efficacy is less well established by evidence/opinion. Conditions for which there is evidence and/or general agreement that a procedure/treatment is not useful/ effective and in some cases may be harmful. ...
2016 Biopharmaceutical Research Industry Profile
... FDA approved several new medicines for pediatric patients in 2015, including many offering treatment options for conditions that previously had few or no options. The first therapy for the treatment of a rare, progressive, metabolic disease called hypophosphatasia (HPP) was approved.27 In its most s ...
... FDA approved several new medicines for pediatric patients in 2015, including many offering treatment options for conditions that previously had few or no options. The first therapy for the treatment of a rare, progressive, metabolic disease called hypophosphatasia (HPP) was approved.27 In its most s ...
Designing Clinical Trials to Evaluate Mucus
... more similar to how an established therapy is used clinically, it is likely that subjects with stable disease will have slower progression of clinical measures, thus requiring a greater sample size and longer duration of observation to reach clinical and statistical significance. Older patients with ...
... more similar to how an established therapy is used clinically, it is likely that subjects with stable disease will have slower progression of clinical measures, thus requiring a greater sample size and longer duration of observation to reach clinical and statistical significance. Older patients with ...
Diagnosis and Treatment of Diffuse Interstitial Lung Diseases
... characteristics, each form of DILD has its own clinical peculiarities (see the specific characteristics of the different forms of DILD). As DILD progresses, pulmonary hypertension may develop and lead to chronic cor pulmonale (edema, hepatomegaly, and jugular venous distension). It is also essential ...
... characteristics, each form of DILD has its own clinical peculiarities (see the specific characteristics of the different forms of DILD). As DILD progresses, pulmonary hypertension may develop and lead to chronic cor pulmonale (edema, hepatomegaly, and jugular venous distension). It is also essential ...
Beyond the Scope Spring 2015 - UCLA Division of Digestive Diseases
... The main ways we do that are through research and innovation, as illustrated in this issue of Beyond the Scope. Beginning on page 2, we list the many sessions during which our faculty are presenting at Digestive Disease Week (DDW) 2015 in Washington, DC. This event, the world’s largest gathering of ...
... The main ways we do that are through research and innovation, as illustrated in this issue of Beyond the Scope. Beginning on page 2, we list the many sessions during which our faculty are presenting at Digestive Disease Week (DDW) 2015 in Washington, DC. This event, the world’s largest gathering of ...
WWW.KPDS.ORG
... E) While a blow powerful enough to fracture the jaw may cause bleeding within the skull ...
... E) While a blow powerful enough to fracture the jaw may cause bleeding within the skull ...
Acute Chest Syndrome of Sickle Cell Disease
... been demonstrated that any pediatric patient with sickle cell disease and fever who presents to the emergency department or clinic would benefit from a chest radiograph, as the clinical assessment of such patients was inadequate to identify ACS in many cases.53 One study of adults suggests that rout ...
... been demonstrated that any pediatric patient with sickle cell disease and fever who presents to the emergency department or clinic would benefit from a chest radiograph, as the clinical assessment of such patients was inadequate to identify ACS in many cases.53 One study of adults suggests that rout ...
the gerontological society of america workgroup on cognitive
... (Okura et al., 2011; Schulz & Beach, 1999; Spillman & Long, 2009). Thus, it is important to maintain the highest possible level of physical functioning and to reduce behavioral symptoms in people with dementia so that they can remain at home longer. In the context of this report, more systematic det ...
... (Okura et al., 2011; Schulz & Beach, 1999; Spillman & Long, 2009). Thus, it is important to maintain the highest possible level of physical functioning and to reduce behavioral symptoms in people with dementia so that they can remain at home longer. In the context of this report, more systematic det ...
Diagnosis and management of adult coeliac disease: guidelines
... atrophy) combined with positive serology (IgA-EMA, tissue transglutaminase (TTG) or IgG-DGP) may also represent CD (‘probable CD’), and in these circumstances a trial with GFD may be considered to further support the diagnosis of CD. HLA status may also aid diagnosis. Differential diagnoses of lymph ...
... atrophy) combined with positive serology (IgA-EMA, tissue transglutaminase (TTG) or IgG-DGP) may also represent CD (‘probable CD’), and in these circumstances a trial with GFD may be considered to further support the diagnosis of CD. HLA status may also aid diagnosis. Differential diagnoses of lymph ...
CURRICULUM VITAE - Test - University of South Florida
... Source: National Institutes of Neurological Disorders and Stroke (NINDS) Title of Project: “Natural history of and genetic modifiers in Spinocerebellar Ataxias (SCA)” Dates of Project: 2010 - 2013 Total Budget: $15,000 Aims: The primary objective of this study is to bring together a group of experts ...
... Source: National Institutes of Neurological Disorders and Stroke (NINDS) Title of Project: “Natural history of and genetic modifiers in Spinocerebellar Ataxias (SCA)” Dates of Project: 2010 - 2013 Total Budget: $15,000 Aims: The primary objective of this study is to bring together a group of experts ...