AusPAR: Trastuzumab
... DNA coding for the humanised immunoglobulin light and heavy chains has been inserted. The drug substance manufacture consists of cell culture fermentation and purification. The master cell bank and the working cell bank remain the same when comparing the production process of trastuzumab SC used to ...
... DNA coding for the humanised immunoglobulin light and heavy chains has been inserted. The drug substance manufacture consists of cell culture fermentation and purification. The master cell bank and the working cell bank remain the same when comparing the production process of trastuzumab SC used to ...
Appendix D: Commonly Used Antihypertensive Drugs 1
... Reference Drug Program. Drugs included in the RDP are comparable agents of the same therapeutic class. Patients receive full coverage of drugs designated as the Reference Drug(s) of the therapeutic class. Other drugs in the same RDP category are covered up to the price of the Reference Drug; No cove ...
... Reference Drug Program. Drugs included in the RDP are comparable agents of the same therapeutic class. Patients receive full coverage of drugs designated as the Reference Drug(s) of the therapeutic class. Other drugs in the same RDP category are covered up to the price of the Reference Drug; No cove ...
NL-2854 Final SmPC - updated for national phase in NL - CBG-MEB
... In such patients the risk of treatment should be considered in relation to possible benefit and clinical monitoring is recommended. If CK levels are significantly elevated at baseline (>5xULN) treatment should not be started. Whilst on Treatment Patients should be asked to report inexplicable muscle ...
... In such patients the risk of treatment should be considered in relation to possible benefit and clinical monitoring is recommended. If CK levels are significantly elevated at baseline (>5xULN) treatment should not be started. Whilst on Treatment Patients should be asked to report inexplicable muscle ...
Intravenous medications in the Emergency Department
... at high doses). Has antiarrhythmic properties and acts to ↓HR, ↓BP, and ↓ contractility in a dose-‐ related manner. Used for Tx of SVT with RVR or HTN Onset of action: 2-‐10 minutes. Du ...
... at high doses). Has antiarrhythmic properties and acts to ↓HR, ↓BP, and ↓ contractility in a dose-‐ related manner. Used for Tx of SVT with RVR or HTN Onset of action: 2-‐10 minutes. Du ...
Methylergonovine Heathcare Professional Letter
... include sufficient number of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in response between the elderly and younger patients. In general dose selection for an elderly patient should ...
... include sufficient number of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in response between the elderly and younger patients. In general dose selection for an elderly patient should ...
here - Farmavita.Net
... acuity cannot be monitored. Patients with Pulmonary Tuberculosis and HIV lnfection: The response of the immunologically impaired host to treatment may not be as satisfactory as that of a person with normal host responsiveness. For this reason, therapeutic decisions for the impaired host must be indi ...
... acuity cannot be monitored. Patients with Pulmonary Tuberculosis and HIV lnfection: The response of the immunologically impaired host to treatment may not be as satisfactory as that of a person with normal host responsiveness. For this reason, therapeutic decisions for the impaired host must be indi ...
JUL -9 2235 ‘Y?
... Appendix 2 of the new information sent May 18, 1998), BioResponse contacted 2 physicians directly supervising 13C supplementation. These responses from physicians following and evaluating RRP patients on 13C supplementation are summarized in Appendix 111, These patients have been adding encapsulated ...
... Appendix 2 of the new information sent May 18, 1998), BioResponse contacted 2 physicians directly supervising 13C supplementation. These responses from physicians following and evaluating RRP patients on 13C supplementation are summarized in Appendix 111, These patients have been adding encapsulated ...
levetiracetam in sodium chloride injection
... compatible and chemically stable for at least 24 hours when mixed with lorazepam, diazepam, and valproate sodium and stored at controlled room temperature 15° to 30°C (59° to 86°F). ...
... compatible and chemically stable for at least 24 hours when mixed with lorazepam, diazepam, and valproate sodium and stored at controlled room temperature 15° to 30°C (59° to 86°F). ...
(embelin)-a second solid gold of india
... combination of embelin and silver sulphadiazine formulation respectively. In contradict to the above observations; Radhakrishnan & co-workers [52] observed inhibitory effect of wound healing in invitro wound healing model studies using fibroblast as well as endothelial cells. However, the reasons fo ...
... combination of embelin and silver sulphadiazine formulation respectively. In contradict to the above observations; Radhakrishnan & co-workers [52] observed inhibitory effect of wound healing in invitro wound healing model studies using fibroblast as well as endothelial cells. However, the reasons fo ...
hydromorphone hydrochloride ciir
... tricyclic antidepressants or other CNS depressants (including alcohol) concomitantly with hydromorphone hydrochloride may exhibit an additive CNS depression. When such combined therapy is contemplated, the dose of one or both agents should be reduced. Pregnancy: Pregnancy Category C. Hydromorphone h ...
... tricyclic antidepressants or other CNS depressants (including alcohol) concomitantly with hydromorphone hydrochloride may exhibit an additive CNS depression. When such combined therapy is contemplated, the dose of one or both agents should be reduced. Pregnancy: Pregnancy Category C. Hydromorphone h ...
Committee on Drugs 1998;101;1079 Pediatrics
... hypertensive episodes, severe mood swings, cerebrovascular accidents, myocardial infarction, and repeated spontaneous abortions.45,46,49 –53 Infant characteristics that may be associated with maternal drug use include prematurity;11,52 unexplained intrauterine growth retardation;50,52 neurobehaviora ...
... hypertensive episodes, severe mood swings, cerebrovascular accidents, myocardial infarction, and repeated spontaneous abortions.45,46,49 –53 Infant characteristics that may be associated with maternal drug use include prematurity;11,52 unexplained intrauterine growth retardation;50,52 neurobehaviora ...
Chapter-3 Drug and Excipients profile
... intravenous preparation for human use, but extrapolation from dog studies would suggest a fairly low and variable systemic bioavailability. When Isotretinoin is taken with food, the bioavailability is doubled relative to fasting conditions. Distribution Isotretinoin is extensively bound to plasma pr ...
... intravenous preparation for human use, but extrapolation from dog studies would suggest a fairly low and variable systemic bioavailability. When Isotretinoin is taken with food, the bioavailability is doubled relative to fasting conditions. Distribution Isotretinoin is extensively bound to plasma pr ...
Systematic Review of Combined Angiotensin
... effective, thereby increasing angiotensin II levels, which could be inhibited by the addition of an angiotensin receptor blocker. We conducted a meta-analysis of randomized trials with searches of MEDLINE, EMBASE, and Cochrane databases. Overall, the combination of an ACE inhibitor and an angiotensi ...
... effective, thereby increasing angiotensin II levels, which could be inhibited by the addition of an angiotensin receptor blocker. We conducted a meta-analysis of randomized trials with searches of MEDLINE, EMBASE, and Cochrane databases. Overall, the combination of an ACE inhibitor and an angiotensi ...
• Increase in Blood Pressure: Monitor blood pressure and... at appropriate intervals. Use with caution in patients for
... who elects to use ADDERALL XR for extended periods should periodically re-evaluate the long-term usefulness of the drug for the individual patient. 2 DOSAGE and ADMINISTRATION 2.1 Dosing Considerations for all Patients Individualize the dosage according to the therapeutic needs and response of the p ...
... who elects to use ADDERALL XR for extended periods should periodically re-evaluate the long-term usefulness of the drug for the individual patient. 2 DOSAGE and ADMINISTRATION 2.1 Dosing Considerations for all Patients Individualize the dosage according to the therapeutic needs and response of the p ...
Risperdal/Risperdal M-Tab/ Risperdal Consta (risperidone)
... At lower dosages, Risperdal is generally well tolerated. Common side effects include sedation, dizziness, headache, nausea, vomiting, constipation, insomnia, and agitation. There is a higher incidence of extrapyramidal symptoms (EPS) when the dosage of Risperdal exceeds 6 mg/day. EPS are neurologica ...
... At lower dosages, Risperdal is generally well tolerated. Common side effects include sedation, dizziness, headache, nausea, vomiting, constipation, insomnia, and agitation. There is a higher incidence of extrapyramidal symptoms (EPS) when the dosage of Risperdal exceeds 6 mg/day. EPS are neurologica ...
Inhibition and induction of human cytochrome P450 (CYP) enzymes
... metabolic routes of a compound have been elucidated and a method is available for their quantitation in in vitro incubations, it is possible to employ ` diagnostic ’ inhibitors (table 2) and to look which of them, and at which concentrations, inhibit metabolic routes. It is also possible to use enzy ...
... metabolic routes of a compound have been elucidated and a method is available for their quantitation in in vitro incubations, it is possible to employ ` diagnostic ’ inhibitors (table 2) and to look which of them, and at which concentrations, inhibit metabolic routes. It is also possible to use enzy ...
Antipsychotic dosing: found in translation
... as it routinely treats adherence/nonadherence as dichotomous and fails to address patterns of nonadherence.67 The PET data with drugs like clozapine and quetiapine indicated that the threshold did not have to be sustained over 24 hours, whereas the depot literature indicated that levels below this t ...
... as it routinely treats adherence/nonadherence as dichotomous and fails to address patterns of nonadherence.67 The PET data with drugs like clozapine and quetiapine indicated that the threshold did not have to be sustained over 24 hours, whereas the depot literature indicated that levels below this t ...
VetyFormula2009
... pints etc). SI stands for Systeme Internationale and it is now recognized as the standard system for measurement in most disciplines around the world. The SI system defines a base unit for a particular measurement (for example the gram for measuring weight) and a prefix (e.g. kilo, milli) when the a ...
... pints etc). SI stands for Systeme Internationale and it is now recognized as the standard system for measurement in most disciplines around the world. The SI system defines a base unit for a particular measurement (for example the gram for measuring weight) and a prefix (e.g. kilo, milli) when the a ...
adderall xr - Shire Canada
... Pharmacokinetic studies of ADDERALL XR (mixed salts amphetamine extended-release capsules) have been conducted in healthy adult and pediatric (aged 6-12 years) subjects, and adolescent (aged 13-17 years) and pediatric patients with ADHD. ADDERALL XR capsules contain dextroamphetamine (d-amphetamine) ...
... Pharmacokinetic studies of ADDERALL XR (mixed salts amphetamine extended-release capsules) have been conducted in healthy adult and pediatric (aged 6-12 years) subjects, and adolescent (aged 13-17 years) and pediatric patients with ADHD. ADDERALL XR capsules contain dextroamphetamine (d-amphetamine) ...
Effects of IV and ICV Hypocretin-1 (Orexin A)
... Figure 1—Effects of a single (upper 2 panels) and repeated (lower panels) intravenous (IV) injections of hypocretin-1 on cataplexy in Hcrtr2-mutated narcoleptic Dobermans. The severity of cataplectic attacks in 6 genetically narcoleptic dogs was evaluated using the Food Elicited Cataplexy Test. Mean ...
... Figure 1—Effects of a single (upper 2 panels) and repeated (lower panels) intravenous (IV) injections of hypocretin-1 on cataplexy in Hcrtr2-mutated narcoleptic Dobermans. The severity of cataplectic attacks in 6 genetically narcoleptic dogs was evaluated using the Food Elicited Cataplexy Test. Mean ...
Levalbuterol HCl Inhalation Solution 0.31 m Levalbuterol
... 3. Use of Anti-Inflammatory Agents: The use of beta-adrenergic agonist bronchodilators alone may not be adequate to control asthma in many patients. Early consideration should be given to adding anti-inflammatory agents, e.g., corticosteroids, to the therapeutic regimen. 4. Cardiovascular Effects: L ...
... 3. Use of Anti-Inflammatory Agents: The use of beta-adrenergic agonist bronchodilators alone may not be adequate to control asthma in many patients. Early consideration should be given to adding anti-inflammatory agents, e.g., corticosteroids, to the therapeutic regimen. 4. Cardiovascular Effects: L ...
Martindale: The Complete Drug Reference
... form of powder, capsules containing powder or enteric-coated granules (which may be opened before use and the contents sprinkled on soft food), enteric-coated tablets, or granules. If pancreatic enzymes are mixed with liquids or food the resulting mixture should not be allowed to stand for more than ...
... form of powder, capsules containing powder or enteric-coated granules (which may be opened before use and the contents sprinkled on soft food), enteric-coated tablets, or granules. If pancreatic enzymes are mixed with liquids or food the resulting mixture should not be allowed to stand for more than ...
Patient`s Instructions for Use Albuterol Sulfate Inhalation Solution
... Beta-Blockers: Beta-adrenergic receptor blocking agents not only block the pulmonary effect of beta-agonists, such as Albuterol Sulfate Inhalation Solution, but may produce severe bronchospasm in asthmatic patients. Therefore, patients with asthma should not normally be treated with betablockers. Ho ...
... Beta-Blockers: Beta-adrenergic receptor blocking agents not only block the pulmonary effect of beta-agonists, such as Albuterol Sulfate Inhalation Solution, but may produce severe bronchospasm in asthmatic patients. Therefore, patients with asthma should not normally be treated with betablockers. Ho ...
Standardization and toxicological satudies of Butea frondosa
... Freedom from insect infestation and contamination has become an important consideration in storage of grain and to maintain a high quality product. This is also an issue to herbal medicine, therefore, for the determination of pest in herbal medicine the classical method of analysis is used during ex ...
... Freedom from insect infestation and contamination has become an important consideration in storage of grain and to maintain a high quality product. This is also an issue to herbal medicine, therefore, for the determination of pest in herbal medicine the classical method of analysis is used during ex ...
A Brief History of Great Discoveries in Pharmacology: In Celebration
... Although pharmacology is a discipline with a rich and enduring heritage, present-day pharmacology is quite a different discipline than the more traditional subject I studied as a graduate student in the early 1960s. The discipline is now deeply rooted in molecular biology and molecular genetics, bot ...
... Although pharmacology is a discipline with a rich and enduring heritage, present-day pharmacology is quite a different discipline than the more traditional subject I studied as a graduate student in the early 1960s. The discipline is now deeply rooted in molecular biology and molecular genetics, bot ...