
Integrated Logic Systems
... Includes web site for ILS module Bioinformatics group: Structural protein interactions and functional annotation with ontologies, textmining, rules Example: Ontology-based literature search at ww.gopubmed.org ...
... Includes web site for ILS module Bioinformatics group: Structural protein interactions and functional annotation with ontologies, textmining, rules Example: Ontology-based literature search at ww.gopubmed.org ...
CE_Helen_sweet tooth_draft - 2009 Sophomore Reading and
... sugar that ultimately signal the brain to stop eating (Gramza).” In other words, people with sweet tooth may have “a need to eat more sugar to feel full (Starr).” In sum, it is proved that human preference for sugars is determined majorly by the Ile as position 110 in GLUT2 instead of other outer in ...
... sugar that ultimately signal the brain to stop eating (Gramza).” In other words, people with sweet tooth may have “a need to eat more sugar to feel full (Starr).” In sum, it is proved that human preference for sugars is determined majorly by the Ile as position 110 in GLUT2 instead of other outer in ...
Information Retrieval Performance and Method
... using the list of AD-related genes/proteins derived earlier as queries, and to parse out drug terms in the retrieved articles later. Here, we particularly withhold the urge of expediently retrieving PubMed abstracts using a conventional query term such as “Alzheimer”. Instead, we built a PubMed quer ...
... using the list of AD-related genes/proteins derived earlier as queries, and to parse out drug terms in the retrieved articles later. Here, we particularly withhold the urge of expediently retrieving PubMed abstracts using a conventional query term such as “Alzheimer”. Instead, we built a PubMed quer ...
Anaplastic Large Cell Lymphoma:- a clinico
... 4. Therapy of peripheral T / NK neoplasm’s – Haem 06 5. Aggressive Peripheral T cell lymphomas – Haem 05 6. Auto hematopoietic SCT in peripheral T cell lymphoma using uniform high dose regimen – Smith et al – BMT 2007 7. Clinical characteristics, Rx outcome and survival of 36 adult pts with 1’ ALCL, ...
... 4. Therapy of peripheral T / NK neoplasm’s – Haem 06 5. Aggressive Peripheral T cell lymphomas – Haem 05 6. Auto hematopoietic SCT in peripheral T cell lymphoma using uniform high dose regimen – Smith et al – BMT 2007 7. Clinical characteristics, Rx outcome and survival of 36 adult pts with 1’ ALCL, ...
Self-Subunit Swapping Occurs in Another Gene Type of Cobalt
... and Rhodococcus sp. N-774 [26]. A proposed metal-binding motif, CXCC, in the NHase activator of Rhodococcus sp. N-771 has been identified, and the activators for Fe-type NHases have been shown to act as metallochaperones [27]. Recently, a cobalt-containing NHase in Rhodococcus rhodochrous J1, which ...
... and Rhodococcus sp. N-774 [26]. A proposed metal-binding motif, CXCC, in the NHase activator of Rhodococcus sp. N-771 has been identified, and the activators for Fe-type NHases have been shown to act as metallochaperones [27]. Recently, a cobalt-containing NHase in Rhodococcus rhodochrous J1, which ...
Many transcription factors recognize DNA shape
... alter binding sites of structural proteins and chromatin modifiers. Approach: CRISPR edit sites identified by TargetFinder, then test chromatin and expression. ...
... alter binding sites of structural proteins and chromatin modifiers. Approach: CRISPR edit sites identified by TargetFinder, then test chromatin and expression. ...
Exercise 8
... Transformation of bacteria is the process in which the cell takes up a molecule of DNA from the environment and incorporates at least some its information into its own heredity. The DNA may contain information that improves the ability of the bacterium to survive and multiply in a given environment, ...
... Transformation of bacteria is the process in which the cell takes up a molecule of DNA from the environment and incorporates at least some its information into its own heredity. The DNA may contain information that improves the ability of the bacterium to survive and multiply in a given environment, ...
Alfalfa Cyclins: Differential Expression during the Cell
... suspension cultured cells that were induced to form somatic embryos with redundant oligonucleotides encoding the conserved amino acid sequences K-Y-E-E-M(I)-Y-Pfor the cyclin A and B type and I-L-V(I)-D-W-L-Vfor the cyclin B class (see Methods for the nucleotide sequences). Positive colonies were is ...
... suspension cultured cells that were induced to form somatic embryos with redundant oligonucleotides encoding the conserved amino acid sequences K-Y-E-E-M(I)-Y-Pfor the cyclin A and B type and I-L-V(I)-D-W-L-Vfor the cyclin B class (see Methods for the nucleotide sequences). Positive colonies were is ...
Genome sequence of Aspergillus luchuensis
... Genes that encoded polypeptides longer than 100 amino acids were used in the analysis. Genes that shared homology with 2 COGs were counted redundantly in each COG. a Genes that shared homology with COGs other than R/S were excluded. ...
... Genes that encoded polypeptides longer than 100 amino acids were used in the analysis. Genes that shared homology with 2 COGs were counted redundantly in each COG. a Genes that shared homology with COGs other than R/S were excluded. ...
Dicot and monocot plants differ in retinoblastoma
... The present study supports the view that the retinoblastoma functions are shared by two distinct retinoblastoma-related (RBR) protein subfamilies in the monocot cereal species, whereas dicot plants have only a single RBR protein. Genes encoding RBR proteins were identified and characterized in alfalf ...
... The present study supports the view that the retinoblastoma functions are shared by two distinct retinoblastoma-related (RBR) protein subfamilies in the monocot cereal species, whereas dicot plants have only a single RBR protein. Genes encoding RBR proteins were identified and characterized in alfalf ...
Dear teacher/student
... different databases. When looking for proteins, the best databases are Swiss-Prot and Uniprot KB. Enter the name of the protein in the search bar. 2. You will probably end up with several hits. All proteins in this list are somehow related to the protein in your query. Use the description to determi ...
... different databases. When looking for proteins, the best databases are Swiss-Prot and Uniprot KB. Enter the name of the protein in the search bar. 2. You will probably end up with several hits. All proteins in this list are somehow related to the protein in your query. Use the description to determi ...
Towards mechanistic models of plant organ growth
... from genome-wide and molecular genetics studies in order to come to a mechanistic understanding of plant growth regulation. This approach will have to be able to cope with, on the one hand, the sheer number of genes involved and, on the other hand, the frequently non-linear interactions resulting fr ...
... from genome-wide and molecular genetics studies in order to come to a mechanistic understanding of plant growth regulation. This approach will have to be able to cope with, on the one hand, the sheer number of genes involved and, on the other hand, the frequently non-linear interactions resulting fr ...
Document
... Larkin, R.M., Alonso, J.M., Ecker, J.R., and Chory, J. (2003). GUN4, a regulator of chlorophyll synthesis and intracellular signaling. Science 299: 902–906. Ankele E, Kindgren P, Pesquet E, Strand A (2007) In vivo visualization of Mg-Protoporphyrin IX, a coordinator of photosynthetic gene expression ...
... Larkin, R.M., Alonso, J.M., Ecker, J.R., and Chory, J. (2003). GUN4, a regulator of chlorophyll synthesis and intracellular signaling. Science 299: 902–906. Ankele E, Kindgren P, Pesquet E, Strand A (2007) In vivo visualization of Mg-Protoporphyrin IX, a coordinator of photosynthetic gene expression ...
Hexose MonoPhosphate (HMP) shunt pathway
... drug reduction, and as a cofactor for some non-synthetic enzymatic reactions. In addition, HMP is used for the production of ribose for nucleotide and nucleic acid synthesis. The hexose monophosphate pathway also allows the entry of some carbohydrates into the glycolytic ...
... drug reduction, and as a cofactor for some non-synthetic enzymatic reactions. In addition, HMP is used for the production of ribose for nucleotide and nucleic acid synthesis. The hexose monophosphate pathway also allows the entry of some carbohydrates into the glycolytic ...
Central Dogma of Genetics
... The Prokaryotic Transcription Process: Initiation of Transcription • Promoters in E. coli generally involve two DNA sequences, centered at -35bp and -10bp upstream from the +1 start site of transcription. • The common E. coli promoter that is used for most transcription has these consensus sequence ...
... The Prokaryotic Transcription Process: Initiation of Transcription • Promoters in E. coli generally involve two DNA sequences, centered at -35bp and -10bp upstream from the +1 start site of transcription. • The common E. coli promoter that is used for most transcription has these consensus sequence ...
Pax1/Pax9-Related Genes in an Agnathan Vertebrate, Lampetra
... of each orthologue are rather well conserved within vertebrates (Krauss et al., 1991; Püschel et al., 1992; Glardon et al., 1997, 1998). In larger scale evolution including changes in the body plan, however, regulatory genes usually have acquired additional expression domains in crown groups that e ...
... of each orthologue are rather well conserved within vertebrates (Krauss et al., 1991; Püschel et al., 1992; Glardon et al., 1997, 1998). In larger scale evolution including changes in the body plan, however, regulatory genes usually have acquired additional expression domains in crown groups that e ...
Problem Set Four
... Q3. The figure below represents the chromosome map of an F- E. coli strain carrying mutations in genes required for lactose catabolism (lac), tryptophan biosynthesis (trp), tyrosine biosynthesis (tyr), and isoleucine biosynthesis (ilv). The strain is also resistant to streptomycin due to a mutation ...
... Q3. The figure below represents the chromosome map of an F- E. coli strain carrying mutations in genes required for lactose catabolism (lac), tryptophan biosynthesis (trp), tyrosine biosynthesis (tyr), and isoleucine biosynthesis (ilv). The strain is also resistant to streptomycin due to a mutation ...
Hexose MonoPhosphate (HMP) shunt pathway
... drug reduction, and as a cofactor for some non-synthetic enzymatic reactions. In addition, HMP is used for the production of ribose for nucleotide and nucleic acid synthesis. The hexose monophosphate pathway also allows the entry of some carbohydrates into the glycolytic ...
... drug reduction, and as a cofactor for some non-synthetic enzymatic reactions. In addition, HMP is used for the production of ribose for nucleotide and nucleic acid synthesis. The hexose monophosphate pathway also allows the entry of some carbohydrates into the glycolytic ...
animal biotechnology
... one of the world's leading companies dedicated to the discovery, analysis, manufacture and commercialization of proteins. LSBC's activities are built around an integrated suite of ultrasensitive, industrial-scale technologies created to realize the full commercial and pharmaceutical potential of bio ...
... one of the world's leading companies dedicated to the discovery, analysis, manufacture and commercialization of proteins. LSBC's activities are built around an integrated suite of ultrasensitive, industrial-scale technologies created to realize the full commercial and pharmaceutical potential of bio ...
Smooth Muscle Actin (1A4) Monoclonal Antibody
... **Research Use Only (RUO)** This product is sold for laboratory research use only, not for human or in-vivo use. ...
... **Research Use Only (RUO)** This product is sold for laboratory research use only, not for human or in-vivo use. ...
regulation of a bacteriophage t4 late gene, soc, which
... early from two promoters located about 750 and 1250 base pairs (bp) upstream, as well as late from a late promoter-like sequence immediately upstream from the soc-coding sequence (see Figure 1). T h e 1050- and 1550-base early transcripts (marked with closed circles in Figure 3) found both in del(39 ...
... early from two promoters located about 750 and 1250 base pairs (bp) upstream, as well as late from a late promoter-like sequence immediately upstream from the soc-coding sequence (see Figure 1). T h e 1050- and 1550-base early transcripts (marked with closed circles in Figure 3) found both in del(39 ...
The DNA sequence of the gene and genetic control sites for the
... frequently follows the sequence ala-X-ala (13) although there is considerable variation in the cleavage site sequence. The five Bacillus signal sequences previously reported include four for which the cleavage site is known from comparisons between the sequence of the precursor protein inferred from ...
... frequently follows the sequence ala-X-ala (13) although there is considerable variation in the cleavage site sequence. The five Bacillus signal sequences previously reported include four for which the cleavage site is known from comparisons between the sequence of the precursor protein inferred from ...
Standard PDF - Wiley Online Library
... fibre length together with the chemical composition of wood are critical factors that determine its material properties and hence its suitability for a specific end use in the wood-processing industry. Wood structure is established during xylogenesis as a result of cambial activity. Wood is formed t ...
... fibre length together with the chemical composition of wood are critical factors that determine its material properties and hence its suitability for a specific end use in the wood-processing industry. Wood structure is established during xylogenesis as a result of cambial activity. Wood is formed t ...
Mycorrhiza
... tissues at different developmental stages and under varying environmental conditions (for a review, see Büttner and Sauer 2000; Lemoine 2000; Williams et al. 2000). These transporters are members of the major facilitator superfamily, which is characterised by a common structural motif consisting of ...
... tissues at different developmental stages and under varying environmental conditions (for a review, see Büttner and Sauer 2000; Lemoine 2000; Williams et al. 2000). These transporters are members of the major facilitator superfamily, which is characterised by a common structural motif consisting of ...
Gene regulatory network

A gene regulatory network or genetic regulatory network (GRN) is a collection of regulators thatinteract with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins.The regulator can be DNA, RNA, protein and their complex. The interaction can be direct or indirect (through their transcribed RNA or translated protein).In general, each mRNA molecule goes on to make a specific protein (or set of proteins). In some cases this protein will be structural, and will accumulate at the cell membrane or within the cell to give it particular structural properties. In other cases the protein will be an enzyme, i.e., a micro-machine that catalyses a certain reaction, such as the breakdown of a food source or toxin. Some proteins though serve only to activate other genes, and these are the transcription factors that are the main players in regulatory networks or cascades. By binding to the promoter region at the start of other genes they turn them on, initiating the production of another protein, and so on. Some transcription factors are inhibitory.In single-celled organisms, regulatory networks respond to the external environment, optimising the cell at a given time for survival in this environment. Thus a yeast cell, finding itself in a sugar solution, will turn on genes to make enzymes that process the sugar to alcohol. This process, which we associate with wine-making, is how the yeast cell makes its living, gaining energy to multiply, which under normal circumstances would enhance its survival prospects.In multicellular animals the same principle has been put in the service of gene cascades that control body-shape. Each time a cell divides, two cells result which, although they contain the same genome in full, can differ in which genes are turned on and making proteins. Sometimes a 'self-sustaining feedback loop' ensures that a cell maintains its identity and passes it on. Less understood is the mechanism of epigenetics by which chromatin modification may provide cellular memory by blocking or allowing transcription. A major feature of multicellular animals is the use of morphogen gradients, which in effect provide a positioning system that tells a cell where in the body it is, and hence what sort of cell to become. A gene that is turned on in one cell may make a product that leaves the cell and diffuses through adjacent cells, entering them and turning on genes only when it is present above a certain threshold level. These cells are thus induced into a new fate, and may even generate other morphogens that signal back to the original cell. Over longer distances morphogens may use the active process of signal transduction. Such signalling controls embryogenesis, the building of a body plan from scratch through a series of sequential steps. They also control and maintain adult bodies through feedback processes, and the loss of such feedback because of a mutation can be responsible for the cell proliferation that is seen in cancer. In parallel with this process of building structure, the gene cascade turns on genes that make structural proteins that give each cell the physical properties it needs.It has been suggested that, because biological molecular interactions are intrinsically stochastic, gene networks are the result of cellular processes and not their cause (i.e. cellular Darwinism). However, recent experimental evidence has favored the attractor view of cell fates.