Pseudo-Replication of [GADV]-Proteins and Origin of Life
... represented by triplets but substantially implemented as singlets. The GNC code comprises four codons (1× 4× 1 = 41 = 4) and four [GADV]-amino acids. It could derive through formally triplet and substantially doublet SNS code, consisting of 16 codons (2× 4× 2 = 42 = 16) and 10 amino acids ([GADV]-am ...
... represented by triplets but substantially implemented as singlets. The GNC code comprises four codons (1× 4× 1 = 41 = 4) and four [GADV]-amino acids. It could derive through formally triplet and substantially doublet SNS code, consisting of 16 codons (2× 4× 2 = 42 = 16) and 10 amino acids ([GADV]-am ...
Fungal negative-stranded RNA virus that is related to bornaviruses
... mycoviruses are associated with latent infections, some hold great promise for exploitation as biological agents to control fungal diseases. For example, the hypovirus that infects the chestnut blight fungal pathogen Cryphonectria parasitica was used successfully to control chestnut blight in Europe ...
... mycoviruses are associated with latent infections, some hold great promise for exploitation as biological agents to control fungal diseases. For example, the hypovirus that infects the chestnut blight fungal pathogen Cryphonectria parasitica was used successfully to control chestnut blight in Europe ...
A glucose-responsive transcription factor that regulates
... a high-carbohydrate diet and shown to consist of a single polypeptide with an apparent molecular mass of 100 kDa. The amino acid sequences of four peptides generated by tryptic digestion were determined. Each peptide was found to match the Williams–Beuren syndrome critical region 14 protein (WBSCR14 ...
... a high-carbohydrate diet and shown to consist of a single polypeptide with an apparent molecular mass of 100 kDa. The amino acid sequences of four peptides generated by tryptic digestion were determined. Each peptide was found to match the Williams–Beuren syndrome critical region 14 protein (WBSCR14 ...
Apoptosis
... mitosis and apoptosis. For example, immune responses to infection are boosted by cell division and finely tuned and curtailed by apoptosis; cells of the gut and skin are renewed through cycles of mitosis and apoptosis; the lactating breast regresses post-lactation by apoptosis. ...
... mitosis and apoptosis. For example, immune responses to infection are boosted by cell division and finely tuned and curtailed by apoptosis; cells of the gut and skin are renewed through cycles of mitosis and apoptosis; the lactating breast regresses post-lactation by apoptosis. ...
Gene7-10
... 5. The lactose pathway operates by induction, when an inducer galactoside prevents the repressor from binding its operator; transcription and translation of the lacZ gene then produce galactosidase, the enzyme that metabolizes -galactosides. 6. Some promoters cannot be recognized by RNA polymerase ( ...
... 5. The lactose pathway operates by induction, when an inducer galactoside prevents the repressor from binding its operator; transcription and translation of the lacZ gene then produce galactosidase, the enzyme that metabolizes -galactosides. 6. Some promoters cannot be recognized by RNA polymerase ( ...
- Horizon Discovery
... defined changes into endogenous genes and rAAV vectors can stimulate homologous recombination (HR) up to 1000-fold over that seen using plasmids. rAAV incorporates targeted changes without the requirement of a double strand DNA-break (DSB), however it has been demonstrated that introduction of a DSB ...
... defined changes into endogenous genes and rAAV vectors can stimulate homologous recombination (HR) up to 1000-fold over that seen using plasmids. rAAV incorporates targeted changes without the requirement of a double strand DNA-break (DSB), however it has been demonstrated that introduction of a DSB ...
The gag proteins of human immunodeficiency virus type 1
... By these two processes - targeting the myristoylated forms of Pr55gag and Prl60gag-pol via a cytoplasmic pathway to the plasma membrane and use of the general transport pathway for transmembrane and secretory proteins for targeting of the HIV transmembrane components gpl20/gp41 - all structural and ...
... By these two processes - targeting the myristoylated forms of Pr55gag and Prl60gag-pol via a cytoplasmic pathway to the plasma membrane and use of the general transport pathway for transmembrane and secretory proteins for targeting of the HIV transmembrane components gpl20/gp41 - all structural and ...
Full-Text PDF
... stress. These genes can be classified into two groups: the first group includes genes related to cell metabolism and stress tolerance, and the second group consists of regulatory genes that encode protein kinases or phosphatases and transcription factors [2]. Transcription factors are DNA-binding pr ...
... stress. These genes can be classified into two groups: the first group includes genes related to cell metabolism and stress tolerance, and the second group consists of regulatory genes that encode protein kinases or phosphatases and transcription factors [2]. Transcription factors are DNA-binding pr ...
Protocol S1.
... HP0087 which presents limited homology with the NLPC-P60 domain. This domain is present in the p60 protein of Listeria monocytogenes which has a PG autolytic activity and was previously predicted to have an endopeptidase activity [5]. Moreover, HP0087 was predicted by Tomb and al. to be secreted [4] ...
... HP0087 which presents limited homology with the NLPC-P60 domain. This domain is present in the p60 protein of Listeria monocytogenes which has a PG autolytic activity and was previously predicted to have an endopeptidase activity [5]. Moreover, HP0087 was predicted by Tomb and al. to be secreted [4] ...
Viral evolution and the emergence of SARS
... hints at higher mutation rates; Sanz et al. 1999). On average, RNA polymerases produce almost one error in each replication cycle (Drake et al. 1998; Malpica et al. 2002), thus when populations of RNA viruses are large, they will produce a myriad of potentially adaptively useful genetic variation. S ...
... hints at higher mutation rates; Sanz et al. 1999). On average, RNA polymerases produce almost one error in each replication cycle (Drake et al. 1998; Malpica et al. 2002), thus when populations of RNA viruses are large, they will produce a myriad of potentially adaptively useful genetic variation. S ...
Oocyte-Specific Expression of Growth/Differentiation Factor-9
... during mammalian embryogenesis (13-l 8); and giiai cell-derived neurotrophic factor, which can promote the survival of midbrain dopaminergic neurons (19). The biologically active forms of these secreted factors are believed to be generated by proteolytic cleavage from a larger precursor protein. For ...
... during mammalian embryogenesis (13-l 8); and giiai cell-derived neurotrophic factor, which can promote the survival of midbrain dopaminergic neurons (19). The biologically active forms of these secreted factors are believed to be generated by proteolytic cleavage from a larger precursor protein. For ...
white - UWL faculty websites
... eukaryotic Traffic ATPases in that they transport their substrates into the cell rather than pumping molecules out of the cell (see Higgins, 1992). Comparison among Traffic ATPase proteins reveals that, although the conservation of amino acid sequence may be low between any two members of the family ...
... eukaryotic Traffic ATPases in that they transport their substrates into the cell rather than pumping molecules out of the cell (see Higgins, 1992). Comparison among Traffic ATPase proteins reveals that, although the conservation of amino acid sequence may be low between any two members of the family ...
Systems-wide Chicken DNA Microarrays, Gene Expression Profiling
... low Blast score. Although 33% of our EST are still classified as unknown genes, they are now assembled in highfidelity contigs, which provides a longer in silico cDNA sequence for future gene identification. About 26% of the unknown EST in the UD collection remain as unknown singlets. Alignment deta ...
... low Blast score. Although 33% of our EST are still classified as unknown genes, they are now assembled in highfidelity contigs, which provides a longer in silico cDNA sequence for future gene identification. About 26% of the unknown EST in the UD collection remain as unknown singlets. Alignment deta ...
Databases
... human genes and their products • Major emphasis on human disease • Links to many kinds of biomedical information • Sequence databases • OMIM, HGMD, MDB • Doctors’ Guide to the Internet July 2002 - CS Course Module: Introduction to Bioinformatics – CS 2001 ...
... human genes and their products • Major emphasis on human disease • Links to many kinds of biomedical information • Sequence databases • OMIM, HGMD, MDB • Doctors’ Guide to the Internet July 2002 - CS Course Module: Introduction to Bioinformatics – CS 2001 ...
Tissue-specific codon usage and the expression of
... mutations that have occurred between them. Although the aligned mouse and human sequences exhibit synonymous differences in 28% of their codons, these differences compensate in such a way so as to preserve the overall codon usage. This result suggests that there has been selection to preserve the co ...
... mutations that have occurred between them. Although the aligned mouse and human sequences exhibit synonymous differences in 28% of their codons, these differences compensate in such a way so as to preserve the overall codon usage. This result suggests that there has been selection to preserve the co ...
Identification of the Missing Links in Prokaryotic Pentose Oxidation
... as a sole carbon and energy source. At present, three main catabolic pathways have been described for pentoses. The first is present in Bacteria and uses isomerases, kinases, and epimerases to convert D- and L-arabinose (Ara) and D-xylose (Xyl) into D-xylulose 5-phosphate (Fig. 1A), which is further ...
... as a sole carbon and energy source. At present, three main catabolic pathways have been described for pentoses. The first is present in Bacteria and uses isomerases, kinases, and epimerases to convert D- and L-arabinose (Ara) and D-xylose (Xyl) into D-xylulose 5-phosphate (Fig. 1A), which is further ...
Nematode lecture
... Functions of Parasitism Proteins Nematodes need to penetrate and migrate through the roots ! ...
... Functions of Parasitism Proteins Nematodes need to penetrate and migrate through the roots ! ...
Gene Section PRUNE (prune exopolyphosphatase) Atlas of Genetics and Cytogenetics
... be divided into two main groups on the basis of a Cterminal motif that is very well conserved within each group, but not across the groups. All the members of this super-family possess four other motifs that contain highly conserved charged residues predicted to be responsible for binding ions and c ...
... be divided into two main groups on the basis of a Cterminal motif that is very well conserved within each group, but not across the groups. All the members of this super-family possess four other motifs that contain highly conserved charged residues predicted to be responsible for binding ions and c ...
Analysis of sequence variations of Calpastatin gene of inhibitory
... leading to fillet degradation. Calpastatin (CAST), an endogenous inhibitor inhibits the ability of calpains to destroy cellular proteins which in association with each other determine how the muscle tissue grows or wastes away. Rainbow trout CAST-L & CAST-S V1 has two inhibitory domains and CAST-S ...
... leading to fillet degradation. Calpastatin (CAST), an endogenous inhibitor inhibits the ability of calpains to destroy cellular proteins which in association with each other determine how the muscle tissue grows or wastes away. Rainbow trout CAST-L & CAST-S V1 has two inhibitory domains and CAST-S ...
Gene Section ANLN (anillin, actin binding protein) Atlas of Genetics and Cytogenetics
... complex is likely to be essential for the growthpromoting pathway and aggressive features of lung cancers as well as for cell division. Moreover n-ANLN whose nuclear localization and stability are regulated by PI3K/AKT signaling, appears to regulate the malignant potential of cancer cells. ...
... complex is likely to be essential for the growthpromoting pathway and aggressive features of lung cancers as well as for cell division. Moreover n-ANLN whose nuclear localization and stability are regulated by PI3K/AKT signaling, appears to regulate the malignant potential of cancer cells. ...
DNA in Action! A 3D Swarm-based Model of a Gene Regulatory
... RNA polymerase (Pol ), the initiator of transcription, is represented as a dark brown sphere (Fig. 5). RNA polymerase has a natural affinity for DNA and is usually found near or on the DNA, which we have incorporated into the model. Once RNA polymerase attaches to a DNA region, it starts scanning al ...
... RNA polymerase (Pol ), the initiator of transcription, is represented as a dark brown sphere (Fig. 5). RNA polymerase has a natural affinity for DNA and is usually found near or on the DNA, which we have incorporated into the model. Once RNA polymerase attaches to a DNA region, it starts scanning al ...
24.8 brief comms MH - Department of Entomology
... has a matching sequence; the small RNA intermediates of this process can also modify gene expression in the nucleus1. Here we show that a single episode of RNAi in the nematode Caenorhabditis elegans can induce transcriptional silencing effects that are inherited indefinitely in the absence of the o ...
... has a matching sequence; the small RNA intermediates of this process can also modify gene expression in the nucleus1. Here we show that a single episode of RNAi in the nematode Caenorhabditis elegans can induce transcriptional silencing effects that are inherited indefinitely in the absence of the o ...
Attack of the Viruses!
... • Prions are composed of proteins but have no nucleic acid to carry genetic information. ...
... • Prions are composed of proteins but have no nucleic acid to carry genetic information. ...
Optimization of Electroporation Conditions for Jurkat Cells - Bio-Rad
... optimization of electroporation conditions prove to be challenging and time consuming. With the introduction of the Gene Pulser MXcell electroporation system, optimal electroporation conditions can be determined quickly, allowing scientists to perform experiments with minimal delay. In this note, we ...
... optimization of electroporation conditions prove to be challenging and time consuming. With the introduction of the Gene Pulser MXcell electroporation system, optimal electroporation conditions can be determined quickly, allowing scientists to perform experiments with minimal delay. In this note, we ...
Endogenous retrovirus
Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). ERVs are a subclass of a type of gene called a transposon, which can be packaged and moved within the genome to serve a vital role in gene expression and in regulation. Researchers have suggested that retroviruses evolved from a type of transposable gene called a retrotransposon, which includes ERVs; these genes can mutate and instead of moving to another location in the genome they can become exogenous or pathogenic. This means that all ERVs may not have originated as an insertion by a retrovirus but that some may have been the source for the genetic information in the retroviruses they resemble.