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Scientific Committee on Emerging and Zoonotic Diseases
Scientific Committee on Emerging and Zoonotic Diseases

... This paper will first discuss how the surveillance systems processing the above-mentioned types of data may be useful in detecting clusters of unusual infectious diseases in humans locally. The latter part of this paper gives an account of the monitoring of unusual disease clusters outside Hong Kong ...
Molecular Evolution and Phylogeography of Co
Molecular Evolution and Phylogeography of Co

... clusters. In contrast, all Italian IHNV isolates fell within genogroup E, for which only a single genetic cluster was identified. More striking was that IHNV has evolved more rapidly than VHSV (mean rates of 11 and 7.3 × 10−4 nucleotide substitutions per site, per year, respectively), indicating tha ...
Immunity and Pathogen Competition
Immunity and Pathogen Competition

... •This is likely to be the case with rhinovirus infection because symptoms occur only after significant virus spread and may even by caused in part by the immune responses themselves Even though “acquired resistance” would spread quickly on an epidemiological level, it is not likely that a newly gen ...
Hendra virus - NSW Department of Primary Industries
Hendra virus - NSW Department of Primary Industries

... In some cases the onset of signs is more gradual, and horses have survived for several days before being euthanased on welfare grounds. Occasionally a horse will survive the infection. The reported mortality rate in infected horses is greater than 70%. ...
Testing Services for Veterinary Vaccines - Sigma
Testing Services for Veterinary Vaccines - Sigma

... Of paramount importance in ensuring the safety of live and inactivated veterinary vaccines is their characterization and demonstration of freedom from extraneous agents. Biological substrates, ingredients and products for veterinary vaccines produced in vivo and in vitro must be investigated for the ...
Novel antibody binding determinants on the capsid surface of
Novel antibody binding determinants on the capsid surface of

... post-electroporation. Extensive CPE were observed at both the first and second passages. At least two independent clones of each virus were rescued. However, only one clone in each case was used for further characterization. In order to prove that the expected viruses had been rescued, reverse trans ...
Hepatitis A
Hepatitis A

... Virus might be replicating ...
Amino acid sequence identity between the HA1 of influenza A
Amino acid sequence identity between the HA1 of influenza A

... HA and neuraminidase of relevant epidemic strains (Maassab et al., 1985). Such viruses are under trial as live attenuated influenza vaccines (Wright et al., 1982; Murphy & Clements, 1989). Because potential reference and vaccine strains of virus may also be initially isolated in mammalian cells of d ...
- LSHTM Research Online
- LSHTM Research Online

... outer capsid proteins, VP2 and VP5, to form mature progeny virions prior to virus egress [41,42]. To understand each step of virus infection more in detail, such as dynamic and multi-step viral entry and intercellular transport of viral proteins, viruses and relevant cellular components are chemical ...
No evidence for a role of modified live virus vaccines in the
No evidence for a role of modified live virus vaccines in the

... confirmed by the partial DNA sequences of isolates from tissues of dogs dying of CPV infection during 1978 and 1979. All three capsid protein gene regions could be analysed from viruses from five dogs (838}78, 1887}78, 1703}79, 2522}79 and 2645}79), and none was an intermediate between CPV and FPV. ...
Recognition and Management of Bioterrorism Infections
Recognition and Management of Bioterrorism Infections

... blood cell count is typically normal or slightly elevated with a left shift.1 Rapid diagnostic testing for influenza can be considered. Cultures of blood and pleural fluid should be obtained. Notifying public health authorities of all confirmed cases of anthrax is mandatory. Laboratory resources fro ...
epidemiology - Devon County Council
epidemiology - Devon County Council

... most likely mechanism of the infection being introduced into the UK. Humans, horses and other animal species are believed to be dead-end hosts, i.e. there is no spread from them to other people or animals. It is possible that a recently infected horse or person, incubating the infection, could have ...
Viral Hepatitis in Infants and Children
Viral Hepatitis in Infants and Children

... High population density Daycare centers and minor epidemics ...
6-Enterically transmitted hepatitis
6-Enterically transmitted hepatitis

...  Usually starts suddenly with anorexia, malaise , nausea , ...
Myxomatosis
Myxomatosis

... of the animal. MYXV strains with different degrees of pathogenicity have arisen since the introduction of MYXV into rabbit populations and these circulate in the field. Mild and attenuated strains cause the amyxomatous (respiratory) form of the disease especially in farmed animals. Wild rabbits act ...
Since the early 70`s a variety of pathological conditions in domestic
Since the early 70`s a variety of pathological conditions in domestic

... belonged to Beta-CoV genus, severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), and caused severe respiratory diseases with case fatality rates of 9% and 36% respectively. The evolutionary origin of SARS-CoV, which was firstly detecte ...
Appendix A: Calculations of transition rates in the outcome tree
Appendix A: Calculations of transition rates in the outcome tree

... The Q fever acute illness is similar to the acute illness of influenza A(H1N1) pdm09, which is used as a proxy for Q fever acute illness, but is different in two aspects. First, those under 15 years of age are far less frequently symptomatic (12.5%) than cases that are over 15 years of age (40%) [1] ...
Hepatitis C Test Menu - Sonora Quest Laboratories
Hepatitis C Test Menu - Sonora Quest Laboratories

... Scores, on a scale of 0.0 to 1.0, are assigned a Metavir scale indicating the level of fibrosis or inflammation present. Please note that this test is not available for patients <2 years old. ...
4. Serological Diagnosis of Infectious Diseases
4. Serological Diagnosis of Infectious Diseases

... Gummas are localized areas of granulomatous inflammation found on bones, skin and subcutaneous tissue. Contain lymphocytes, plasma cells and perivascular inflammation. ...
Culex mosquitoes are experimentally unable to
Culex mosquitoes are experimentally unable to

... mosquitoes and 170 Cx. quinquefasciatus examined for vector competence. Mosquitoes were orally infected with an Asian genotype ZIKV (strain NC-2014–5132), originally isolated from a patient in New Caledonia in April 2014. The ZIKV strain is phylogenetically closely related to those currently circula ...
Pneumonia
Pneumonia

... Risks: age extremes, hospitalized pts, intubated, tracheostomy, immunosuppressed, recent surgery, pts with cystic fibrosis, IVDU (who are prone to tricuspid valve endocarditis with resultant embolic pneumonia) ...
The Avian Influenza
The Avian Influenza

... H9N2, Hong Kong, 2003 : H9N2 infection was confirmed in a child in Hong Kong. The child was hospitalized but recovered. H7N2, New York, 2003: In November 2003, a patient with serious underlying medical conditions was admitted to a hospital in New York with respiratory symptoms. One of the initial la ...
Viral hepatitis
Viral hepatitis

... – RT-PCR of faeces. ...
Chapter 21
Chapter 21

... – Known to jump from animals to humans; human-to-human transmission is very limited • Seen some cases the USA recently – Disease closely resembles smallpox in symptoms and mortality rate – Prevention by smallpox vaccination ...
J V , Apr. 2006, p. 3675–3678 Vol. 80, No. 7
J V , Apr. 2006, p. 3675–3678 Vol. 80, No. 7

... which the PFU reaches 50% of its final value, estimated here by averaging the total PFU at 11, 12, and 14 h. The width of the distribution about the mean was likewise estimated by noting the points at which the PFU reached 16 and 84% of its final value, corresponding to plus and minus 1 standard dev ...
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