Drugs acting on sympathetic α and β receptors Agonists - Di-Et-Tri
... * Digoxin and fluoxetin inhibit appetite * Stimulation of appetite: most SSRI’s, TCA’s, Valproate, Cannabis Drug effects on nutrient absorption? ; Laxantives (some) ; (old) cholesterol lowering drugs (colestyramine) ; Orlistat Take care with already diminished uptake (mal-absorption syndrome) and de ...
... * Digoxin and fluoxetin inhibit appetite * Stimulation of appetite: most SSRI’s, TCA’s, Valproate, Cannabis Drug effects on nutrient absorption? ; Laxantives (some) ; (old) cholesterol lowering drugs (colestyramine) ; Orlistat Take care with already diminished uptake (mal-absorption syndrome) and de ...
Antidepressant drugs - Dr Lynch
... reversible MAOB – weak MAOA activity, little antidepressant activity Adverse effects similar to tricyclics but non-sedative. ? addiction syndrome for some older MAOIs. Cheese reaction, drug interaction, hepatotoxicity, neurotoxicity Fewer adverse effects for moclobemide ? Differential effects on dop ...
... reversible MAOB – weak MAOA activity, little antidepressant activity Adverse effects similar to tricyclics but non-sedative. ? addiction syndrome for some older MAOIs. Cheese reaction, drug interaction, hepatotoxicity, neurotoxicity Fewer adverse effects for moclobemide ? Differential effects on dop ...
Depression and Suicide
... reversible MAOB – weak MAOA activity, little antidepressant activity Adverse effects similar to tricyclics but non-sedative. ? addiction syndrome for some older MAOIs. Cheese reaction, drug interaction, hepatotoxicity, neurotoxicity Fewer adverse effects for moclobemide ? Differential effects on dop ...
... reversible MAOB – weak MAOA activity, little antidepressant activity Adverse effects similar to tricyclics but non-sedative. ? addiction syndrome for some older MAOIs. Cheese reaction, drug interaction, hepatotoxicity, neurotoxicity Fewer adverse effects for moclobemide ? Differential effects on dop ...
Document
... Briefly describe two ways in which the therapeutic and side effects of the atypical antipsychotic drug clozapine are similar to or different from those of the “classical” antipsychotics. For each difference or similarity, please provide the likely mechanism. ...
... Briefly describe two ways in which the therapeutic and side effects of the atypical antipsychotic drug clozapine are similar to or different from those of the “classical” antipsychotics. For each difference or similarity, please provide the likely mechanism. ...
Drugs and Toxicology
... is all that is necessary (“aggregate weight based law”) Quantitative analysis indicates how much of that sample is made up of a controlled substance (percentage of the total for each controlled substance present in a sample) © 2007 The McGraw-Hill Companies, all rights reserved. ...
... is all that is necessary (“aggregate weight based law”) Quantitative analysis indicates how much of that sample is made up of a controlled substance (percentage of the total for each controlled substance present in a sample) © 2007 The McGraw-Hill Companies, all rights reserved. ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... the rate of protein synthesis and degradation. This report has also been presented by Dworkin et al., (2003) when the albino rats were treated with panadol (an analgesic). The significant increase (P>0.05) in amylase activity showed in the animals administered with the drug may suggest that the drug ...
... the rate of protein synthesis and degradation. This report has also been presented by Dworkin et al., (2003) when the albino rats were treated with panadol (an analgesic). The significant increase (P>0.05) in amylase activity showed in the animals administered with the drug may suggest that the drug ...
- Integration of Psychiatry into Primary Health Care
... • Nil in general related to COPD – Consider co-morbidities (e.g. chronic renal failure) – Consider pharmacokinetic and pharmacodynamic changes with ongoing cigarette smoking • Bronchoconstriction • Induction of CYP1A2, 2B6, 2D6 ...
... • Nil in general related to COPD – Consider co-morbidities (e.g. chronic renal failure) – Consider pharmacokinetic and pharmacodynamic changes with ongoing cigarette smoking • Bronchoconstriction • Induction of CYP1A2, 2B6, 2D6 ...
MIGRAINE
... Ergotamine can be given by all routes. Orally undergoes extensive 1st pass metabolism. Sublingual has a bioavailability less than 1% Rectal route best method of absorption Nasal spray I.M. , SC, I.V. ...
... Ergotamine can be given by all routes. Orally undergoes extensive 1st pass metabolism. Sublingual has a bioavailability less than 1% Rectal route best method of absorption Nasal spray I.M. , SC, I.V. ...
PPT
... can be obtained from graded dose-response curve. In quantal dose response curve, ED50, TD50 and LD50 are potency variables. ...
... can be obtained from graded dose-response curve. In quantal dose response curve, ED50, TD50 and LD50 are potency variables. ...
Sustained Release Dosage Forms The Sustained
... that combine chemically with other agents forming complexes that may be slowly soluble in body fluids. ...
... that combine chemically with other agents forming complexes that may be slowly soluble in body fluids. ...
OFLOMED® 200 mg Tablets Dear patient, Please read
... inflammation, or rupture of a tendon, if any symptom of an allergic reaction occurs or if severe diarrhea occurs during treatment. -This drug should be used with caution in patients with a known or suspected central nervous system disorder that may predispose to seizures or in the presence of other ...
... inflammation, or rupture of a tendon, if any symptom of an allergic reaction occurs or if severe diarrhea occurs during treatment. -This drug should be used with caution in patients with a known or suspected central nervous system disorder that may predispose to seizures or in the presence of other ...
Designing concept maps for a precise and objective
... study the monographs for each drug in the set, section by section, comparing the properties of each drug with those of the new drug. This process is time-consuming and unrealistic. The national and international drug agencies (EMA [1], Afssaps [2], HAS [3], FDA [4]) publish evaluation reports for ea ...
... study the monographs for each drug in the set, section by section, comparing the properties of each drug with those of the new drug. This process is time-consuming and unrealistic. The national and international drug agencies (EMA [1], Afssaps [2], HAS [3], FDA [4]) publish evaluation reports for ea ...
Jay Williams, PhD`s Blog
... At the 2014 annual meeting of the American College of Gastroenterologists, Dr. James Ehrlich presented data proving that 38% BPF significantly improved liver structure and function in patients with both metabolic syndrome and fatty liver disease. The study involved authors from 3 continents and was ...
... At the 2014 annual meeting of the American College of Gastroenterologists, Dr. James Ehrlich presented data proving that 38% BPF significantly improved liver structure and function in patients with both metabolic syndrome and fatty liver disease. The study involved authors from 3 continents and was ...
Introduction to Basic Therapeutics Module
... • Understand computer assisted learning in experimental Pharmacology • Briefly overview the concept of pharmacology ...
... • Understand computer assisted learning in experimental Pharmacology • Briefly overview the concept of pharmacology ...
完全沒有, 有一點,相當多,非常多
... clinically significant side effects, whereas others may have no therapeutic response. ...
... clinically significant side effects, whereas others may have no therapeutic response. ...
OTC Drugs, Herbal Remedies and Other Stuff Chapter 14
... Effective for people with problems; may not have much effect for “normals” ...
... Effective for people with problems; may not have much effect for “normals” ...
Detection of the pharmaceutical agent glaucine as a recreational drug
... and quantification. The measured serum concentration of 0.7 mg/L should therefore only be considered an approximation. Extended toxicological screening did not detect ethanol or any other drugs, except for cyclizine, which was administered in the ED. Glaucine is an antitussive agent used therapeutic ...
... and quantification. The measured serum concentration of 0.7 mg/L should therefore only be considered an approximation. Extended toxicological screening did not detect ethanol or any other drugs, except for cyclizine, which was administered in the ED. Glaucine is an antitussive agent used therapeutic ...
Family Education Rights and Privacy Act (FERPA)
... drugs, and is not intended to be an exhaustive or final statement of all possible health consequences of substance abuse. Alcohol: Alcohol consumption has acute effects on the body and causes a number of marked changes in behavior. Even low doses may significantly impair judgment and coordination. A ...
... drugs, and is not intended to be an exhaustive or final statement of all possible health consequences of substance abuse. Alcohol: Alcohol consumption has acute effects on the body and causes a number of marked changes in behavior. Even low doses may significantly impair judgment and coordination. A ...
Sedatives
... because recovery is more rapid when compared with thiopental. Has been referred to as "milk of amnesia" because of the milk-like appearance of its iv preparation. Not scheduled, easy to obtain, and wears off quickly, so is abused. Most likely by medical staff because access & skill. ...
... because recovery is more rapid when compared with thiopental. Has been referred to as "milk of amnesia" because of the milk-like appearance of its iv preparation. Not scheduled, easy to obtain, and wears off quickly, so is abused. Most likely by medical staff because access & skill. ...
Drug Combination Analysis - Civilized Software, Inc.
... D1 in the presence of drug D2 , which itself has an independent effect. When a12 is 0, there is no interaction. The greater a12 and e12 are, the greater is the dose-dependent potentiation effect of drug D2 on drug D1 . When a12 is negative, drug D2 has an inhibitory effect on drug D1 . Fitting such ...
... D1 in the presence of drug D2 , which itself has an independent effect. When a12 is 0, there is no interaction. The greater a12 and e12 are, the greater is the dose-dependent potentiation effect of drug D2 on drug D1 . When a12 is negative, drug D2 has an inhibitory effect on drug D1 . Fitting such ...
Advisory Committee Mtgs. Sample PPT
... The Regulation • 21 CFR 361 Prescription Drugs for Human Use Generally Recognized as Safe and Effective and Not ...
... The Regulation • 21 CFR 361 Prescription Drugs for Human Use Generally Recognized as Safe and Effective and Not ...
File
... pharmacokinetic parameters • The two basic pharmacokinetics parameters are volume of distribution and Clearance • (A good strategy for understanding the topic of pharmacokinetics is to read on the following and tackle the examples) ...
... pharmacokinetic parameters • The two basic pharmacokinetics parameters are volume of distribution and Clearance • (A good strategy for understanding the topic of pharmacokinetics is to read on the following and tackle the examples) ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.